| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Cannabidiol | Alzheimer's Disease | 35 | PM | 38785534 | 📋 | Modulation of Oxidative Stress and Neuroinflammation by Cannabidiol (CBD): Promising Targets for the Treatment of Alzheimer's Disease |
| Cannabidiol | Alzheimer's Disease | 34 | PM | 38590254 | 📋 | Cannabidiol improves the cognitive function of SAMP8 AD model mice involving the microbiota-gut-brain axis |
| Cannabidiol | Alzheimer's Disease | 33 | PM | 38067101 | 📋 | Assessing Cannabidiol as a Therapeutic Agent for Preventing and Alleviating Alzheimer's Disease Neurodegeneration |
| Cannabidiol | Alzheimer's Disease | 32 | PM | 37959001 | 📋 | An In Silico Study for Expanding the Utility of Cannabidiol in Alzheimer's Disease Therapeutic Development |
| Cannabidiol | Alzheimer's Disease | 31 | PM | 37892128 | 📋 | The Main Therapeutic Applications of Cannabidiol (CBD) and Its Potential Effects on Aging with Respect to Alzheimer's Disease |
| Cannabidiol | Alzheimer's Disease | 30 | PM | 37602231 | 📋 | Synergetic effect of β-asarone and cannabidiol against Aβ aggregation in vitro and in vivo |
| Cannabidiol | Alzheimer's Disease | 29 | PM | 36544841 | 📋 | The gut microbiota in neurodegenerative diseases: revisiting possible therapeutic targets for cannabidiol |
| Cannabidiol | Alzheimer's Disease | 24 | PM | 36238565 | 📋 | Effect of long-term cannabidiol on learning and anxiety in a female Alzheimer's disease mouse model |
| Cannabidiol | Alzheimer's Disease | 23 | PM | 35628181 | 📋 | Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation |
| Cannabidiol | Alzheimer's Disease | 28 | PM | 35385645 | 📋 | Effect of Cannabidiol on the Neural Glyoxalase Pathway Function and Longevity of Several C. elegans Strains Including a C. elegans Alzheimer's Disease Model |
| Cannabidiol | Alzheimer's Disease | 27 | PM | 35202719 | 📋 | Cannabidiol (CBD) treatment improves spatial memory in 14-month-old female TAU58/2 transgenic mice |
| Cannabidiol | Alzheimer's Disease | 26 | PM | 35181336 | 📋 | Cannabidiol protects against Alzheimer's disease in C. elegans via ROS scavenging activity of its phenolic hydroxyl groups |
| Cannabidiol | Alzheimer's Disease | 25 | PM | 35163003 | 📋 | Cannabidiol Treatment Improves Glucose Metabolism and Memory in Streptozotocin-Induced Alzheimer's Disease Rat Model: A Proof-of-Concept Study |
| Cannabidiol | Alzheimer's Disease | 22 | PM | 34944028 | 📋 | Cannabidiol Inhibits Tau Aggregation In Vitro |
| Cannabidiol | Alzheimer's Disease | 21 | PM | 34573232 | 📋 | Understanding the Modulatory Effects of Cannabidiol on Alzheimer's Disease |
| Cannabidiol | Alzheimer's Disease | 20 | PM | 33817834 | 📋 | Cannabidiol regulates CB1-pSTAT3 signaling for neurite outgrowth, prolongs lifespan, and improves health span in Caenorhabditis elegans of Aβ pathology models |
| Cannabidiol | Alzheimer's Disease | 19 | PM | 33797364 | 📋 | Roles of Cannabidiol in the treatment and prevention of Alzheimer's disease by multi-target actions |
| Cannabidiol | Alzheimer's Disease | 18 | PM | 33096116 | 📋 | Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq |
| Cannabidiol | Alzheimer's Disease | 17 | PM | 32640965 | 📋 | Impact of Cannabis-Based Medicine on Alzheimer's Disease by Focusing on the Amyloid β- Modifications: A Systematic Study |
| Cannabidiol | Alzheimer's Disease | 9 | PM | 32210795 | 📋 | From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases |
| Cannabidiol | Alzheimer's Disease | 2 | PM | 29574668 | 📋 | Cannabidiol Reverses Deficits in Hippocampal LTP in a Model of Alzheimer's Disease |
| Cannabidiol | Alzheimer's Disease | 8 | PM | 28981597 | 📋 | Effects of Cannabidiol Interactions With Wnt/β-catenin Pathway and PPARγ on Oxidative Stress and Neuroinflammation in Alzheimer's Disease |
| Cannabidiol | Alzheimer's Disease | 11 | PM | 28412918 | 📋 | Neurological Aspects of Medical Use of Cannabidiol |
| Cannabidiol | Alzheimer's Disease | 15 | PM | 28217094 | 📋 | In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease |
| Cannabidiol | Alzheimer's Disease | 12 | PM | 28025562 | 📋 | Cannabidiol Modulates the Expression of Alzheimer's Disease-Related Genes in Mesenchymal Stem Cells |
| Cannabidiol | Alzheimer's Disease | 16 | PM | 27471947 | 📋 | The Therapeutic Potential of the Phytocannabinoid Cannabidiol for Alzheimer's Disease |
| Cannabidiol | Alzheimer's Disease | 7 | PM | 27137221 | 📋 | Pharmacological Management of Agitation and Aggression in Alzheimer's Disease: A Review of Current and Novel Treatments |
| Cannabidiol | Alzheimer's Disease | 5 | PM | 27110749 | 📋 | Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview |
| Cannabidiol | Alzheimer's Disease | 3 | PM | 25125475 | 📋 | Cannabis-based Medicine Reduces Multiple Pathological Processes in AβPP/PS1 Mice |
| Cannabidiol | Alzheimer's Disease | 4 | PM | 17592514 | 📋 | Cannabidiol in Vivo Blunts Beta-Amyloid Induced Neuroinflammation by Suppressing IL-1beta and iNOS Expression |
| Cannabidiol | Alzheimer's Disease | 13 | PM | 16490313 | 📋 | Cannabidiol Inhibits Inducible Nitric Oxide Synthase Protein Expression and Nitric Oxide Production in Beta-Amyloid Stimulated PC12 Neurons Through p38 MAP Kinase and NF-kappaB Involvement |
| Cannabidiol | Alzheimer's Disease | 14 | PM | 16389547 | 📋 | The Marijuana Component Cannabidiol Inhibits Beta-Amyloid-Induced Tau Protein Hyperphosphorylation Through Wnt/beta-catenin Pathway Rescue in PC12 Cells |
| Cannabidiol | Alzheimer's Disease | 10 | PM | 15728830 | 📋 | Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation |
| Cannabidiol | Alzheimer's Disease | 6 | PM | 15030397 | 📋 | Neuroprotective Effect of Cannabidiol, a Non-Psychoactive Component From Cannabis Sativa, on Beta-Amyloid-Induced Toxicity in PC12 Cells |
| Cannabidiol | Alzheimer's Disease | 1 | PM | 9309469 | 📋 | Effects of Dronabinol on Anorexia and Disturbed Behavior in Patients With Alzheimer's Disease |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 1 | PM | 30520038 | 📋 | Effects of Cannabinoids in Amyotrophic Lateral Sclerosis (ALS) Murine Models: A Systematic Review and Meta-Analysis |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 8 | PM | 27714895 | 📋 | Gingival Stromal Cells as an In Vitro Model: Cannabidiol Modulates Genes Linked With Amyotrophic Lateral Sclerosis |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 5 | PM | 24703394 | 📋 | Changes in Endocannabinoid Receptors and Enzymes in the Spinal Cord of SOD1(G93A) Transgenic Mice and Evaluation of a Sativex(®) -Like Combination of Phytocannabinoids: Interest for Future Therapies in Amyotrophic Lateral Sclerosis |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 9 | PM | 20439484 | 📋 | Cannabis and Amyotrophic Lateral Sclerosis: Hypothetical and Practical Applications, and a Call for Clinical Trials |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 7 | PM | 20353778 | 📋 | The Endocannabinoid System in the Inflammatory and Neurodegenerative Processes of Multiple Sclerosis and of Amyotrophic Lateral Sclerosis |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 10 | PM | 18781981 | 📋 | The Endocannabinoid System in Amyotrophic Lateral Sclerosis |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 6 | PM | 17241118 | 📋 | The CB2 Cannabinoid Agonist AM-1241 Prolongs Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis When Initiated at Symptom Onset |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 2 | PM | 16781706 | 📋 | AM1241, a Cannabinoid CB2 Receptor Selective Compound, Delays Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 3 | PM | 16183560 | 📋 | Cannabinol Delays Symptom Onset in SOD1 (G93A) Transgenic Mice Without Affecting Survival |
| Cannabidiol | Amyotrophic Lateral Sclerosis | 4 | PM | 15204022 | 📋 | Amyotrophic Lateral Sclerosis: Delayed Disease Progression in Mice by Treatment With a Cannabinoid |
| Cannabidiol | CDKL5 Deficiency Disorder | 2 | PM | 38654472 | 📋 | Cannabidiol attenuates seizure susceptibility and behavioural deficits in adult CDKL5R59X knock-in mice |
| Cannabidiol | CDKL5 Deficiency Disorder | 1 | PM | 33754312 | 📋 | Highly Purified Cannabidiol for Epilepsy Treatment: A Systematic Review of Epileptic Conditions Beyond Dravet Syndrome and Lennox-Gastaut Syndrome |
| Cannabidiol | Dravet Syndrome | 21 | PM | 38500226 | 📋 | The efficacy and safety of cannabidiol (CBD) in pediatric patients with Dravet Syndrome: a narrative review of clinical trials |
| Cannabidiol | Dravet Syndrome | 20 | PM | 37290534 | 📋 | Disease-modifying effects of cannabidiol, β-caryophyllene and their combination in Syn1-Cre/Scn1aWT/A1783V mice, a preclinical model of Dravet syndrome |
| Cannabidiol | Dravet Syndrome | 19 | PM | 34992485 | 📋 | Channelopathy of Dravet Syndrome and Potential Neuroprotective Effects of Cannabidiol |
| Cannabidiol | Dravet Syndrome | 18 | PM | 34486101 | 📋 | Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain |
| Cannabidiol | Dravet Syndrome | 17 | PM | 34406656 | 📋 | Add-on cannabidiol in patients with Dravet syndrome: Results of a long-term open-label extension trial |
| Cannabidiol | Dravet Syndrome | 16 | PM | 34308420 | 📋 | Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome |
| Cannabidiol | Dravet Syndrome | 15 | PM | 34265088 | 📋 | Time to onset of cannabidiol treatment effects in Dravet syndrome: Analysis from two randomized controlled trials |
| Cannabidiol | Dravet Syndrome | 14 | PM | 34093420 | 📋 | Results From an Italian Expanded Access Program on Cannabidiol Treatment in Highly Refractory Dravet Syndrome and Lennox-Gastaut Syndrome |
| Cannabidiol | Dravet Syndrome | 13 | PM | 34052628 | 📋 | Two-center experience of cannabidiol use in adults with Dravet syndrome |
| Cannabidiol | Dravet Syndrome | 11 | PM | 33908026 | 📋 | New therapeutic approach in Dravet syndrome and Lennox-Gastaut syndrome with cannabidiol |
| Cannabidiol | Dravet Syndrome | 10 | PM | 33395525 | 📋 | Cannabichromene, Related Phytocannabinoids, and 5-Fluoro-cannabichromene Have Anticonvulsant Properties in a Mouse Model of Dravet Syndrome |
| Cannabidiol | Dravet Syndrome | 9 | PM | 33372424 | 📋 | Cannabidiol for Treating Lennox-Gastaut Syndrome and Dravet Syndrome in Korea |
| Cannabidiol | Dravet Syndrome | 8 | PM | 33026899 | 📋 | Practical use of pharmaceutically purified oral cannabidiol in Dravet syndrome and Lennox-Gastaut syndrome |
| Cannabidiol | Dravet Syndrome | 1 | PM | 32040850 | 📋 | Adjunctive Cannabidiol in Patients With Dravet Syndrome: A Systematic Review and Meta-Analysis of Efficacy and Safety |
| Cannabidiol | Dravet Syndrome | 6 | PM | 30938373 | 📋 | Cannabidiol as Adjunctive Treatment of Seizures Associated With Lennox-Gastaut Syndrome and Dravet Syndrome |
| Cannabidiol | Dravet Syndrome | 4 | PM | 30582156 | 📋 | Long-term Cannabidiol Treatment in Patients With Dravet Syndrome: An Open-Label Extension Trial |
| Cannabidiol | Dravet Syndrome | 12 | PM | 30250864 | 📋 | A prospective open-label trial of a CBD/THC cannabis oil in dravet syndrome |
| Cannabidiol | Dravet Syndrome | 7 | PM | 29929108 | 📋 | The Adult Motor Phenotype of Dravet Syndrome Is Associated With Mutation of the STXBP1 Gene and Responds Well to Cannabidiol Treatment |
| Cannabidiol | Dravet Syndrome | 5 | PM | 28973916 | 📋 | Cannabidiol Attenuates Seizures and Social Deficits in a Mouse Model of Dravet Syndrome |
| Cannabidiol | Dravet Syndrome | 3 | PM | 28538134 | 📋 | Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome |
| Cannabidiol | Dravet Syndrome | 2 | PM | 27069631 | 📋 | Analysis of Endocannabinoid Signaling Elements and Related Proteins in Lymphocytes of Patients With Dravet Syndrome |
| Cannabidiol | Epidermolysis Bullosa | 1 | PM | 30347109 | 📋 | Combined Tetrahydrocannabinol and Cannabidiol to Treat Pain in Epidermolysis Bullosa: A Report of Three Cases |
| Cannabidiol | Fragile X Syndrome | 1 | PM | 36624400 | 📋 | Role of the endocannabinoid system in fragile X syndrome: potential mechanisms for benefit from cannabidiol treatment |
| Cannabidiol | Huntington's Disease | 7 | PM | 29562549 | 📋 | Cannabinoids for Treatment of Dystonia in Huntington's Disease |
| Cannabidiol | Huntington's Disease | 1 | PM | 27159993 | 📋 | A Double-Blind, Randomized, Cross-Over, Placebo-Controlled, Pilot Trial With Sativex in Huntington's Disease |
| Cannabidiol | Huntington's Disease | 2 | PM | 25252936 | 📋 | Neuroprotective Properties of Cannabigerol in Huntington's Disease: Studies in R6/2 Mice and 3-nitropropionate-lesioned Mice |
| Cannabidiol | Huntington's Disease | 4 | PM | 22860209 | 📋 | Sativex-like Combination of Phytocannabinoids Is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington's Disease: Role of CB1 and CB2 Receptors |
| Cannabidiol | Huntington's Disease | 3 | PM | 21674569 | 📋 | Neuroprotective Effects of Phytocannabinoid-Based Medicines in Experimental Models of Huntington's Disease |
| Cannabidiol | Huntington's Disease | 5 | PM | 19228959 | 📋 | Cannabidiol Targets Mitochondria to Regulate Intracellular Ca2+ Levels |
| Cannabidiol | Huntington's Disease | 6 | PM | 17672854 | 📋 | Cannabidiol Reduced the Striatal Atrophy Caused 3-nitropropionic Acid in Vivo by Mechanisms Independent of the Activation of Cannabinoid, Vanilloid TRPV1 and Adenosine A2A Receptors |
| Cannabidiol | Rett Syndrome | 1 | PM | 33010341 | 📋 | Chronic treatment with cannabidiolic acid (CBDA) reduces thermal pain sensitivity in male mice and rescues the hyperalgesia in a mouse model of Rett syndrome |
| Cannabidiol | Tuberous Sclerosis | 4 | PM | 35175622 | 📋 | Time to Onset of Cannabidiol (CBD) Treatment Effect and Resolution of Adverse Events in Tuberous Sclerosis Complex: Post Hoc Analysis of Randomized Controlled Phase 3 Trial GWPCARE6 |
| Cannabidiol | Tuberous Sclerosis | 3 | PM | 34957550 | 📋 | Long-term cannabidiol treatment for seizures in patients with tuberous sclerosis complex: An open-label extension trial |
| Cannabidiol | Tuberous Sclerosis | 2 | PM | 33346789 | 📋 | Add-On Cannabidiol Treatment for Drug-Resistant Seizures in Tuberous Sclerosis Complex: A Placebo-Controlled Randomized Clinical Trial |
| Cannabidiol | Tuberous Sclerosis | 1 | PM | 27696387 | 📋 | Cannabidiol as a New Treatment for Drug-Resistant Epilepsy in Tuberous Sclerosis Complex |
