| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| EGCG | Adenomyosis | 1 | PM | 23703534 | 📋 | Epigallocatechin-3-gallate reduces myometrial infiltration, uterine hyperactivity, and stress levels and alleviates generalized hyperalgesia in mice induced with adenomyosis |
| EGCG | Breast Cancer | 34 | PM | 38201092 | 📋 | Comparative Anticancer Potential of Green Tea Extract and Epigallocatechin-3-gallate on Breast Cancer Spheroids |
| EGCG | Breast Cancer | 33 | PM | 37833751 | 📋 | EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells |
| EGCG | Breast Cancer | 32 | PM | 37445915 | 📋 | The Potential Role of Epigallocatechin-3-Gallate (EGCG) in Breast Cancer Treatment |
| EGCG | Breast Cancer | 28 | PM | 35325850 | 📋 | The influence of antioxidant dietary-derived polyphenolic combination on breast cancer: Molecular study |
| EGCG | Breast Cancer | 27 | PM | 34473289 | 📋 | Anticancer potential of (-)-epicatechin in a triple-negative mammary gland model |
| EGCG | Breast Cancer | 26 | PM | 33801973 | 📋 | EGCG Inhibits Adipose-Derived Mesenchymal Stem Cells Differentiation into Adipocytes and Prevents a STAT3-Mediated Paracrine Oncogenic Control of Triple-Negative Breast Cancer Cell Invasive Phenotype |
| EGCG | Breast Cancer | 25 | PM | 33745223 | 📋 | CCN5 activation by free or encapsulated EGCG is required to render triple-negative breast cancer cell viability and tumor progression |
| EGCG | Breast Cancer | 24 | PM | 33319659 | 📋 | The Role of EGCG in Breast Cancer Prevention and Therapy |
| EGCG | Breast Cancer | 18 | PM | 33113766 | 📋 | Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers |
| EGCG | Breast Cancer | 17 | PM | 33083333 | 📋 | Assessment Synergistic Effects of Integrated Therapy with Epigallocatechin-3-Gallate (EGCG) & Arsenic Trioxide and Irradiation on Breast Cancer Cell Line |
| EGCG | Breast Cancer | 13 | PM | 32290071 | 📋 | Green Tea Polyphenol EGCG Attenuates MDSCs-mediated Immunosuppression Through Canonical and Non-Canonical Pathways in a 4T1 Murine Breast Cancer Model |
| EGCG | Breast Cancer | 11 | PM | 31404982 | 📋 | The Inhibitory Effect of (-)-Epigallocatechin-3-Gallate on Breast Cancer Progression via Reducing SCUBE2 Methylation and DNMT Activity |
| EGCG | Breast Cancer | 1 | PM | 29040973 | 📋 | Sulforaphane and Epigallocatechin Gallate Restore Estrogen Receptor Expression by Modulating Epigenetic Events in the Breast Cancer Cell Line MDA-MB-231: A Systematic Review and Meta-Analysis |
| EGCG | Breast Cancer | 31 | PM | 28927122 | 📋 | Mechanism of EGCG promoting apoptosis of MCF-7 cell line in human breast cancer |
| EGCG | Breast Cancer | 3 | PM | 28646740 | 📋 | Epigallocatechin-3-gallate Promotes Apoptosis in Human Breast Cancer T47D Cells Through Down-Regulation of PI3K/AKT and Telomerase |
| EGCG | Breast Cancer | 16 | PM | 26273208 | 📋 | Phytochemicals Modulate Carcinogenic Signaling Pathways in Breast and Hormone-Related Cancers |
| EGCG | Breast Cancer | 6 | PM | 25550533 | 📋 | Curcumin and Epigallocatechin Gallate Inhibit the Cancer Stem Cell Phenotype via Down-Regulation of STAT3-NFκB Signaling |
| EGCG | Breast Cancer | 10 | PM | 25243063 | 📋 | Increased Chemopreventive Effect by Combining Arctigenin, Green Tea Polyphenol and Curcumin in Prostate and Breast Cancer Cells |
| EGCG | Breast Cancer | 7 | PM | 25242081 | 📋 | Epigallocatechin-3-gallate Potentiates the Effect of Curcumin in Inducing Growth Inhibition and Apoptosis of Resistant Breast Cancer Cells |
| EGCG | Breast Cancer | 29 | PM | 24039951 | 📋 | Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells |
| EGCG | Breast Cancer | 30 | PM | 23664836 | 📋 | Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism |
| EGCG | Breast Cancer | 23 | PM | 23646788 | 📋 | Epigallocatechin-3-Gallate (EGCG) inhibits cell proliferation and migratory behaviour of triple negative breast cancer cells |
| EGCG | Breast Cancer | 2 | PM | 22280355 | 📋 | Anti-cancer Activities of Tea epigallocatechin-3-gallate in Breast Cancer Patients Under Radiotherapy |
| EGCG | Breast Cancer | 20 | PM | 20596647 | 📋 | Inhibition of catechol-Omicron-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG |
| EGCG | Breast Cancer | 21 | PM | 20446926 | 📋 | (-)-Epigallocatechin-3-gallate down-regulates EGFR, MMP-2, MMP-9 and EMMPRIN and inhibits the invasion of MCF-7 tamoxifen-resistant cells |
| EGCG | Breast Cancer | 9 | PM | 20149610 | 📋 | (-)-Epigallocatechin-3-gallate Downregulates Pg-P and BCRP in a Tamoxifen Resistant MCF-7 Cell Line |
| EGCG | Breast Cancer | 12 | PM | 18813800 | 📋 | Suppression of Cell Proliferation and Gene Expression by Combinatorial Synergy of EGCG, Resveratrol and Gamma-Tocotrienol in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells |
| EGCG | Breast Cancer | 15 | PM | 18454305 | 📋 | Biochanin A Inhibits Breast Cancer Tumor Growth in a Murine Xenograft Model |
| EGCG | Breast Cancer | 14 | PM | 18098290 | 📋 | The Combination of Epigallocatechin Gallate and Curcumin Suppresses ER Alpha-Breast Cancer Cell Growth in Vitro and in Vivo |
| EGCG | Breast Cancer | 22 | PM | 18061364 | 📋 | (-)-Epigallocatechin-3-gallate downregulates estrogen receptor alpha function in MCF-7 breast carcinoma cells |
| EGCG | Breast Cancer | 19 | PM | 18059161 | 📋 | Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells |
| EGCG | Breast Cancer | 8 | PM | 17575143 | 📋 | Activation of FOXO3a by the Green Tea Polyphenol epigallocatechin-3-gallate Induces Estrogen Receptor Alpha Expression Reversing Invasive Phenotype of Breast Cancer Cells |
| EGCG | Breast Cancer | 5 | PM | 16519995 | 📋 | Green Tea Polyphenols and Its Constituent Epigallocatechin Gallate Inhibits Proliferation of Human Breast Cancer Cells in Vitro and in Vivo |
| EGCG | Breast Cancer | 4 | PM | 15756018 | 📋 | Growth Inhibitory and Antimetastatic Effect of Green Tea Polyphenols on Metastasis-Specific Mouse Mammary Carcinoma 4T1 Cells in Vitro and in Vivo Systems |
| EGCG | Cervical Cancer | 10 | PM | 37544940 | 📋 | EGCG attenuate EGF triggered matrix abundance and migration in HPV positive and HPV negative cervical cancer cells |
| EGCG | Cervical Cancer | 8 | PM | 34126197 | 📋 | Suppressing effects of Green tea extract and Epigallocatechin-3-gallate (EGCG) on TGF-β- induced Epithelial-to-mesenchymal transition via ROS/Smad signaling in human cervical cancer cells |
| EGCG | Cervical Cancer | 7 | PM | 33257842 | 📋 | A novel cancer preventative botanical mixture, TriCurin, inhibits viral transcripts and the growth of W12 cervical cells harbouring extrachromosomal or integrated HPV16 DNA |
| EGCG | Cervical Cancer | 6 | PM | 33117625 | 📋 | Epigallocatechin gallate inhibits HeLa cells by modulation of epigenetics and signaling pathways |
| EGCG | Cervical Cancer | 4 | PM | 31013600 | 📋 | Enoxacin and Epigallocatechin Gallate (EGCG) Act Synergistically to Inhibit the Growth of Cervical Cancer Cells in Culture |
| EGCG | Cervical Cancer | 1 | PM | 30783443 | 📋 | Epigallocatechin Gallate Inhibits Cell Growth and Regulates miRNA Expression in Cervical Carcinoma Cell Lines Infected With Different High-Risk Human Papillomavirus Subtypes |
| EGCG | Cervical Cancer | 3 | PM | 30390323 | 📋 | Theaflavin and epigallocatechin-3-gallate Synergistically Induce Apoptosis Through Inhibition of PI3K/Akt Signaling Upon Depolymerizing Microtubules in HeLa Cells |
| EGCG | Cervical Cancer | 2 | PM | 26554336 | 📋 | Epigallocatechin-3-gallate Shows Anti-Proliferative Activity in HeLa Cells Targeting Tubulin-Microtubule Equilibrium |
| EGCG | Cervical Cancer | 9 | PM | 24065519 | 📋 | EGCG suppresses Fused Toes Homolog protein through p53 in cervical cancer cells |
| EGCG | Cervical Cancer | 5 | PM | 12804120 | 📋 | A Major Constituent of Green Tea, EGCG, Inhibits the Growth of a Human Cervical Cancer Cell Line, CaSki Cells, Through Apoptosis, G(1) Arrest, and Regulation of Gene Expression |
| EGCG | Cholestasis of Pregnancy | 1 | PM | 28477356 | 📋 | Epigallocatechin-3-gallate ameliorates intrahepatic cholestasis of pregnancy by inhibiting matrix metalloproteinase-2 and matrix metalloproteinase-9 |
| EGCG | Choriocarcinoma | 1 | PM | 27208402 | 📋 | Green Tea (-)-Epigallocatechin Gallate Induced Growth Inhibition of Human Placental Choriocarcinoma Cells |
| EGCG | Endometrial Cancer | 3 | PM | 33113766 | 📋 | Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers |
| EGCG | Endometrial Cancer | 2 | PM | 29024813 | 📋 | A Prodrug of Green Tea Polyphenol (-)-epigallocatechin-3-gallate (Pro-EGCG) Serves as a Novel Angiogenesis Inhibitor in Endometrial Cancer |
| EGCG | Endometrial Cancer | 1 | PM | 19321194 | 📋 | Regulation of Vascular Endothelial Growth Factor in Endometrial Tumour Cells by Resveratrol and EGCG |
| EGCG | Endometriosis | 1 | PM | 34620005 | 📋 | Therapeutic effects of green tea on endometriosis |
| EGCG | Endometriosis | 2 | PM | 32840012 | 📋 | Effect of epigallocatechin-3-gallate on the status of DNA methylation of E-cadherin promoter region on endometriosis mouse |
| EGCG | Endometritis | 1 | PM | 36056792 | 📋 | Epigallocatechin-3-gallate (EGCG) attenuates inflammatory responses and oxidative stress in lipopolysaccharide (LPS)-induced endometritis via silent information regulator transcript-1 (SIRT1)/nucleotide oligomerization domain (NOD)-like receptor pyrin domain-containing 3 (NLRP3) pathway |
| EGCG | Gestational Diabetes | 1 | PM | 28266082 | 📋 | Dietary epigallocatechin 3-gallate supplement improves maternal and neonatal treatment outcome of gestational diabetes mellitus: a double-blind randomised controlled trial |
| EGCG | Gynecological Disorders | 1 | PM | 38398883 | 📋 | Epigallocatechin Gallate for the Treatment of Benign and Malignant Gynecological Diseases-Focus on Epigenetic Mechanisms |
| EGCG | Infertility Female | 3 | PM | 38010042 | 📋 | Epigallocatechin-3-gallate improves the quality of maternally aged oocytes |
| EGCG | Infertility Female | 2 | PM | 34318927 | 📋 | Epigallocatechin-3-gallate stimulates StAR expression and progesterone production in human granulosa cells through the 67-kDa laminin receptor-mediated CREB signaling pathway |
| EGCG | Infertility Female | 1 | PM | 33707939 | 📋 | Epigallocatechin-3-Gallate Promotes the in vitro Maturation and Embryo Development Following IVF of Porcine Oocytes |
| EGCG | Ovarian Cancer | 9 | PM | 38313051 | 📋 | S100A4/NF-κB axis mediates the anticancer effect of epigallocatechin-3-gallate in platinum-resistant ovarian cancer |
| EGCG | Ovarian Cancer | 8 | PM | 38038884 | 📋 | Epigallocatechin gallate inhibits ovarian cancer cell growth and induces cell apoptosis via activation of FOXO3A |
| EGCG | Ovarian Cancer | 7 | PM | 37189618 | 📋 | Epigallocatechin-3-Gallate Prevents the Acquisition of a Cancer Stem Cell Phenotype in Ovarian Cancer Tumorspheres through the Inhibition of Src/JAK/STAT3 Signaling |
| EGCG | Ovarian Cancer | 6 | PM | 33116412 | 📋 | The Potential Roles of Epigallocatechin-3-Gallate in the Treatment of Ovarian Cancer: Current State of Knowledge |
| EGCG | Ovarian Cancer | 5 | PM | 33113766 | 📋 | Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers |
| EGCG | Ovarian Cancer | 4 | PM | 32236585 | 📋 | PTEN/AKT/mTOR Signaling Mediates Anticancer Effects of epigallocatechin‑3‑gallate in Ovarian Cancer |
| EGCG | Ovarian Cancer | 3 | PM | 23333498 | 📋 | Epigallocatechin Gallate and Sulforaphane Combination Treatment Induce Apoptosis in Paclitaxel-Resistant Ovarian Cancer Cells Through hTERT and Bcl-2 Down-Regulation |
| EGCG | Ovarian Cancer | 2 | PM | 16402374 | 📋 | Epigallocatechin-3-gallate Delivers Hydrogen Peroxide to Induce Death of Ovarian Cancer Cells and Enhances Their Cisplatin Susceptibility |
| EGCG | Ovarian Cancer | 1 | PM | 15350370 | 📋 | Anticancer Effects of (-)-epigallocatechin-3-gallate on Ovarian Carcinoma Cell Lines |
| EGCG | Preeclampsia | 5 | PM | 38838579 | 📋 | Epigallocatechin gallate (EGCG) alleviates inflammation and endothelial dysfunction and improves pregnancy outcomes in preeclampsia (PE)-like rats via eNOS/Nrf2/HO-1 pathway |
| EGCG | Preeclampsia | 4 | PM | 38397756 | 📋 | EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of Preeclampsia |
| EGCG | Preeclampsia | 2 | PM | 35211881 | 📋 | The Efficacy Mechanism of Epigallocatechin Gallate against Pre-Eclampsia based on Network Pharmacology and Molecular Docking |
| EGCG | Preeclampsia | 1 | PM | 33056943 | 📋 | Epigallocatechin Gallate (EGCG) Improves Anti-Angiogenic State, Cell Viability, and Hypoxia-Induced Endothelial Dysfunction by Downregulating High Mobility Group Box 1 (HMGB1) in Preeclampsia |
| EGCG | Preeclampsia | 3 | PM | 28726273 | 📋 | Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia: A double-blind, randomized and placebo-controlled clinical study |
| EGCG | Reproductive Toxicity Female | 2 | PM | 35981663 | 📋 | Epigallocatechin-3-gallate attenuates cyclophosphamide-induced damage in mouse ovarian tissue via suppressing inflammation, apoptosis, and expression of phosphorylated Akt, FOXO3a and rpS6 |
| EGCG | Reproductive Toxicity Female | 1 | PM | 34601223 | 📋 | Epigallocatechin gallate and theaflavins independently alleviate cyclophosphamide-induced ovarian damage by inhibiting the overactivation of primordial follicles and follicular atresia |
| EGCG | Uterine Leiomyomas | 11 | PM | 38837949 | 📋 | Advancements and Emerging Therapies in the Medical Management of Uterine Fibroids: A Comprehensive Scoping Review |
| EGCG | Uterine Leiomyomas | 10 | PM | 37958957 | 📋 | Evidence-Based Approach for Secondary Prevention of Uterine Fibroids (The ESCAPE Approach) |
| EGCG | Uterine Leiomyomas | 9 | PM | 37739343 | 📋 | The combination of natural compounds Crila and epigallocatechin gallate (EGCG) showed enhanced antiproliferative effects on human uterine fibroid cells compared to single treatments |
| EGCG | Uterine Leiomyomas | 7 | PM | 37231028 | 📋 | Targeting fibrotic signaling pathways by EGCG as a therapeutic strategy for uterine fibroids |
| EGCG | Uterine Leiomyomas | 6 | PM | 34658291 | 📋 | Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: a pilot, prospective, daily-diary based study |
| EGCG | Uterine Leiomyomas | 5 | PM | 33877649 | 📋 | Uterine fibroids treatment: do we have new valid alternative? Experiencing the combination of vitamin D plus epigallocatechin gallate in childbearing age affected women |
| EGCG | Uterine Leiomyomas | 4 | PM | 33797759 | 📋 | Nutraceuticals in fibroid management after ulipristal acetate administration: An observational study on patients' compliance |
| EGCG | Uterine Leiomyomas | 3 | PM | 32423112 | 📋 | The Evolving Role of Natural Compounds in the Medical Treatment of Uterine Fibroids |
| EGCG | Uterine Leiomyomas | 2 | PM | 32271452 | 📋 | Vitamin D Plus Epigallocatechin Gallate: A Novel Promising Approach for Uterine Myomas |
| EGCG | Uterine Leiomyomas | 8 | PM | 23950663 | 📋 | Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study |
| EGCG | Uterine Leiomyomas | 1 | PM | 19083394 | 📋 | Chemoprevention of Fibroid Tumors by [-]-epigallocatechin-3-gallate in Quail |
