| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Metformin | Diabetes | 24 | PM | 37414069 | 📋 | Safety and effectiveness of metformin plus lifestyle intervention compared with lifestyle intervention alone in preventing progression to diabetes in a Chinese population with impaired glucose regulation: a multicentre, open-label, randomised controlled trial |
| Metformin | Diabetes | 23 | PM | 37354076 | 📋 | Oxidative brain and cerebellum injury in diabetes and prostate cancer model: Protective effect of metformin |
| Metformin | Diabetes | 21 | PM | 37229936 | 📋 | Dihydromyricetin promotes GLP-1 release and glucose uptake by STC-1 cells and enhances the effects of metformin upon STC-1 cells and diabetic mouse model |
| Metformin | Diabetes | 20 | PM | 37094549 | 📋 | Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases |
| Metformin | Diabetes | 19 | PM | 37055870 | 📋 | Antihypertensive and antihyperglycemic effects of combinations of losartan with metformin and/or glibenclamide in desoxycorticosterone acetate and streptozotocin-induced hypertensive diabetic rats |
| Metformin | Diabetes | 18 | PM | 36496468 | 📋 | Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide- induced diabetic rats |
| Metformin | Diabetes | 17 | PM | 36347820 | 📋 | Metformin promotes smear conversion in tuberculosis-diabetes comorbidity and construction of prediction models |
| Metformin | Diabetes | 16 | PM | 35843348 | 📋 | Metformin use and brain atrophy in nondemented elderly individuals with diabetes |
| Metformin | Diabetes | 3 | PM | 35300567 | 📋 | Effects of Capsaicin on the Hypoglycemic Regulation of Metformin and Gut Microbiota Profiles in Type 2 Diabetic Rats |
| Metformin | Diabetes | 13 | PM | 35056687 | 📋 | Development and Greenness Assessment of HPLC Method for Studying the Pharmacokinetics of Co-Administered Metformin and Papaya Extract |
| Metformin | Diabetes | 4 | PM | 34900765 | 📋 | The impact of cichorium intybus L. On GDF-15 level in obese diabetic albino mice as compared with metformin effect |
| Metformin | Diabetes | 6 | PM | 34568732 | 📋 | The effects of gallic acid and metformin on male reproductive dysfunction in diabetic mice induced by methylglyoxal: An experimental study |
| Metformin | Diabetes | 7 | PM | 34345595 | 📋 | Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed streptozotocin-induced diabetic rats |
| Metformin | Diabetes | 15 | PM | 32532388 | 📋 | Metformin and Berberine suppress glycogenolysis by inhibiting glycogen phosphorylase and stabilizing the molecular structure of glycogen in db/db mice |
| Metformin | Diabetes | 2 | PM | 32184858 | 📋 | In-vitro Synergistic Effect of Metformin and Berberine on High Glucose-induced Lipogenesis |
| Metformin | Diabetes | 10 | PM | 32180335 | 📋 | Citrus fruit-derived flavonoid naringenin and the expression of hepatic organic cation transporter 1 protein in diabetic rats treated with metformin |
| Metformin | Diabetes | 9 | PM | 31792920 | 📋 | Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells |
| Metformin | Diabetes | 8 | PM | 30981189 | 📋 | Antidiabetic Effect of Mangiferin in Combination With Oral Hypoglycemic Agents Metformin and Gliclazide |
| Metformin | Diabetes | 22 | PM | 29228766 | 📋 | The effects of addition of coenzyme Q10 to metformin on sirolimus-induced diabetes mellitus |
| Metformin | Diabetes | 5 | PM | 27551311 | 📋 | Comparative anti-inflammatory and lipid-normalizing effects of metformin and omega-3 fatty acids through modulation of transcription factors in diabetic rats |
| Metformin | Diabetes | 11 | PM | 27247923 | 📋 | Nigella sativa seed decreases endothelial dysfunction in streptozotocin-induced diabetic rat aorta |
| Metformin | Diabetes | 14 | PM | 26941537 | 📋 | Bio-enhancing Effect of Piperine With Metformin on Lowering Blood Glucose Level in Alloxan Induced Diabetic Mice |
| Metformin | Diabetes | 12 | PM | 21584245 | 📋 | The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content |
| Metformin | Diabetes | 1 | PM | 18543386 | 📋 | Scutellaria Baicalensis Enhances the Anti-Diabetic Activity of Metformin in Streptozotocin-Induced Diabetic Wistar Rats |
| Metformin | Endocrine Disorders | 1 | PM | 38098114 | 📋 | Safety and antitumor activity of metformin plus lanreotide in patients with advanced gastro-intestinal or lung neuroendocrine tumors: the phase Ib trial MetNET2 |
| Metformin | Glucose Metabolism Disorder | 4 | PM | 37209947 | 📋 | Metabolic Complications of Glucocorticoids - Prevention by Metformin |
| Metformin | Glucose Metabolism Disorder | 3 | PM | 37094549 | 📋 | Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases |
| Metformin | Glucose Metabolism Disorder | 2 | PM | 36593662 | 📋 | Metformin modulates the gut microbiome in a mice model of high-fat diet-induced glycolipid metabolism disorder |
| Metformin | Glucose Metabolism Disorder | 1 | PM | 32532388 | 📋 | Metformin and Berberine suppress glycogenolysis by inhibiting glycogen phosphorylase and stabilizing the molecular structure of glycogen in db/db mice |
| Metformin | Hyperprolactinemia | 3 | PM | 37297964 | 📋 | The Effect of Metformin on Plasma Prolactin Levels in Young Women with Autoimmune Thyroiditis |
| Metformin | Hyperprolactinemia | 2 | PM | 36739860 | 📋 | Myo-Inositol Potentiates the Inhibitory Effect of Metformin on Prolactin Levels |
| Metformin | Hyperprolactinemia | 1 | PM | 35721320 | 📋 | Metformin in the Treatment of Amisulpride-Induced Hyperprolactinemia: A Clinical Trial |
| Metformin | Hyperprolactinemia | 4 | PM | 29169197 | 📋 | Sex-Dependent Effect of Metformin on Serum Prolactin Levels In Hyperprolactinemic Patients With Type 2 Diabetes: A Pilot Study |
| Metformin | Hyperthyroidism | 1 | PM | 35354137 | 📋 | The neuroprotective effect of alpha lipoic acid and/or metformin against the behavioral and neurochemical changes induced by hypothyroidism in rat |
| Metformin | Hypothyroidism | 3 | PM | 36404819 | 📋 | Metformin and alpha lipoic acid ameliorate hypothyroidism and its complications in adult male rats |
| Metformin | Hypothyroidism | 2 | PM | 35852011 | 📋 | Thyroid antibody titers and hypothalamic-pituitary-thyroid axis activity in levothyroxine-treated women with autoimmune subclinical hypothyroidism receiving atorvastatin or metformin |
| Metformin | Hypothyroidism | 1 | PM | 31948119 | 📋 | Both Matricaria chamomilla and Metformin Extract Improved the Function and Histological Structure of Thyroid Gland in Polycystic Ovary Syndrome Rats through Antioxidant Mechanism |
| Metformin | Insulin Resistance | 24 | PM | 38091524 | 📋 | Combination therapy of metformin and morin attenuates insulin resistance, inflammation, and oxidative stress in skeletal muscle of high-fat diet-fed mice |
| Metformin | Insulin Resistance | 23 | PM | 37969194 | 📋 | Metformin ameliorates insulin resistance, thyroid nodules and thyroid function |
| Metformin | Insulin Resistance | 22 | PM | 37584610 | 📋 | Metformin and exercise effects on postprandial insulin sensitivity and glucose kinetics in pre-and-diabetic adults |
| Metformin | Insulin Resistance | 21 | PM | 37583410 | 📋 | A Pilot Study to Assess Effect of Metformin Therapy on Prevention of Double Diabetes in Indian Adolescents with Type-1 Diabetes |
| Metformin | Insulin Resistance | 20 | PM | 36500596 | 📋 | Combined Effects of Lycopene and Metformin on Decreasing Oxidative Stress by Triggering Endogenous Antioxidant Defenses in Diet-Induced Obese Mice |
| Metformin | Insulin Resistance | 19 | PM | 36361210 | 📋 | Overweight and Obese Adult Patients Show Larger Benefits from Concurrent Training Compared with Pharmacological Metformin Treatment on Insulin Resistance and Fat Oxidation |
| Metformin | Insulin Resistance | 18 | PM | 36058289 | 📋 | Metformin alleviates long-term high-fructose diet-induced skeletal muscle insulin resistance in rats by regulating purine nucleotide cycle |
| Metformin | Insulin Resistance | 16 | PM | 35986566 | 📋 | Rapamycin/metformin co-treatment normalizes insulin sensitivity and reduces complications of metabolic syndrome in type 2 diabetic mice |
| Metformin | Insulin Resistance | 17 | PM | 35985506 | 📋 | Metformin, testosterone, or both in men with obesity and low testosterone: A double-blind, parallel-group, randomized controlled trial |
| Metformin | Insulin Resistance | 15 | PM | 35890109 | 📋 | Metabolic Action of Metformin |
| Metformin | Insulin Resistance | 14 | PM | 35822185 | 📋 | Combination of electroacupuncture and pharmacological treatment improves insulin resistance in women with polycystic ovary syndrome: Double-blind randomized clinical trial |
| Metformin | Insulin Resistance | 3 | PM | 35326230 | 📋 | Combination Effects of Metformin and a Mixture of Lemon Balm and Dandelion on High-Fat Diet-Induced Metabolic Alterations in Mice |
| Metformin | Insulin Resistance | 12 | PM | 35145895 | 📋 | Aqueous and alcoholic extracts of Artemisia annua L. improved insulin resistance via decreasing TNF-alpha, IL-6 and free fatty acids in high-fat diet/streptozotocin-induced diabetic mice |
| Metformin | Insulin Resistance | 8 | PM | 34579018 | 📋 | Perilla Seed Oil Alleviates Gut Dysbiosis, Intestinal Inflammation and Metabolic Disturbance in Obese-Insulin-Resistant Rats |
| Metformin | Insulin Resistance | 10 | PM | 34407851 | 📋 | Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis |
| Metformin | Insulin Resistance | 1 | PM | 34375188 | 📋 | Astaxanthin Attenuates Adiponectin, Calprotectin, miRNA222 and miRNA378 in Obesity induced by High-Fat Diet in Rats |
| Metformin | Insulin Resistance | 2 | PM | 34371883 | 📋 | Effect of a New Formulation of Nutraceuticals as an Add-On to Metformin Monotherapy for Patients with Type 2 Diabetes and Suboptimal Glycemic Control: A Randomized Controlled Trial |
| Metformin | Insulin Resistance | 13 | PM | 32080865 | 📋 | Combination of metformin and berberine represses the apoptosis of sebocytes in high-fat diet-induced diabetic hamsters and an insulin-treated human cell line |
| Metformin | Insulin Resistance | 5 | PM | 31005715 | 📋 | Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility |
| Metformin | Insulin Resistance | 11 | PM | 29205344 | 📋 | Synergistic actions of vitamin D and metformin on skeletal muscles and insulin resistance of type 2 diabetic rats |
| Metformin | Insulin Resistance | 9 | PM | 27482073 | 📋 | Beneficial Effects of Combined Resveratrol and Metformin Therapy in Treating Diet-Induced Insulin Resistance |
| Metformin | Insulin Resistance | 6 | PM | 24026800 | 📋 | Grape Seed Proanthocyanidins and Metformin Act by Different Mechanisms to Promote Insulin Signaling in Rats Fed High Calorie Diet |
| Metformin | Insulin Resistance | 7 | PM | 21584245 | 📋 | The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content |
| Metformin | Insulin Resistance | 4 | PM | 19535835 | 📋 | Insulin Sensitizing Actions of Fenugreek Seed Polyphenols, Quercetin & Metformin in a Rat Model |
| Metformin | Pituitary Tumor | 2 | PM | 38147953 | 📋 | Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway |
| Metformin | Pituitary Tumor | 1 | PM | 28962892 | 📋 | Effects of metformin on cell growth and AMPK activity in pituitary adenoma cell cultures, focusing on the interaction with adenylyl cyclase activating signals |
| Metformin | Polycystic Ovary Syndrome | 73 | PM | 38735598 | 📋 | Spirulina versus metformin for controlling some insulin signaling pathway genes in induced polycystic ovary syndrome rat model |
| Metformin | Polycystic Ovary Syndrome | 72 | PM | 38484797 | 📋 | Effects of melatonin and metformin on the ovaries of rats with polycystic ovary syndrome |
| Metformin | Polycystic Ovary Syndrome | 71 | PM | 38425153 | 📋 | Efficacy of metformin combined with vitamin D in the treatment of polycystic ovarian syndrome: A meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 70 | PM | 38397951 | 📋 | The Comparative Effects of Myo-Inositol and Metformin Therapy on the Clinical and Biochemical Parameters of Women of Normal Weight Suffering from Polycystic Ovary Syndrome |
| Metformin | Polycystic Ovary Syndrome | 69 | PM | 38155665 | 📋 | Comparative effects of acupuncture and metformin on insulin sensitivity in overweight/obese and lean women with polycystic ovary syndrome and insulin resistance: a post hoc analysis of a randomized trial |
| Metformin | Polycystic Ovary Syndrome | 68 | PM | 38131036 | 📋 | Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients |
| Metformin | Polycystic Ovary Syndrome | 67 | PM | 37931721 | 📋 | Lavender and metformin effectively propagate progesterone levels in patients with polycystic ovary syndrome: A randomized, double-blind clinical trial |
| Metformin | Polycystic Ovary Syndrome | 66 | PM | 37791160 | 📋 | Role of Metformin in Polycystic Ovary Syndrome (PCOS)-Related Infertility |
| Metformin | Polycystic Ovary Syndrome | 65 | PM | 37736515 | 📋 | Investigation of the effects of astaxanthin in experimental polycystic ovary syndrome (PCOS) in rats |
| Metformin | Polycystic Ovary Syndrome | 64 | PM | 37575860 | 📋 | Myoinositol Versus Metformin in the Treatment of Polycystic Ovarian Syndrome: A Systematic Review |
| Metformin | Polycystic Ovary Syndrome | 63 | PM | 37554096 | 📋 | Metformin and combined oral contraceptive pills in the management of polycystic ovary syndrome: a systematic review and meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 62 | PM | 37536294 | 📋 | The impact of metformin with or without lifestyle modification versus placebo on polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials |
| Metformin | Polycystic Ovary Syndrome | 61 | PM | 37406658 | 📋 | Low dose of liraglutide combined with metformin leads to a significant weight loss in Chinese Han women with polycystic ovary syndrome: a retrospective study |
| Metformin | Polycystic Ovary Syndrome | 60 | PM | 37381009 | 📋 | The effects of metformin on anti-Müllerian hormone levels in patients with polycystic ovary syndrome: a systematic review and meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 59 | PM | 37354674 | 📋 | METFORMIN EFFECTS ON NEUREGULIN-1 IN POLYCYSTIC OVARIAN WOMEN |
| Metformin | Polycystic Ovary Syndrome | 58 | PM | 37354673 | 📋 | METFORMIN EFFECTS ON BLOOD LEVELS OF GREMLIN-1 IN POLYCYSTIC OVARIAN WOMEN |
| Metformin | Polycystic Ovary Syndrome | 52 | PM | 37275752 | 📋 | Protective effect of astaxanthin and metformin in the liver of rats in which the polycystic ovary syndrome model was formed by giving letrozole |
| Metformin | Polycystic Ovary Syndrome | 51 | PM | 37265016 | 📋 | A randomized controlled trial comparing myoinositol with metformin versus metformin monotherapy in polycystic ovary syndrome |
| Metformin | Polycystic Ovary Syndrome | 50 | PM | 37244286 | 📋 | Metformin inhibits ovarian granular cell pyroptosis through the miR-670-3p/NOX2/ROS pathway |
| Metformin | Polycystic Ovary Syndrome | 49 | PM | 37166881 | 📋 | THE THERAPEUTIC EFFECT OF ORAL INSULIN SENSITIZER METFORMIN ON LIPID PROFILE IN WOMEN WITH POLYCYSTIC OVARY SYNDROME |
| Metformin | Polycystic Ovary Syndrome | 48 | PM | 37148410 | 📋 | Effects of myo-inositol vs. metformin on hormonal and metabolic parameters in women with PCOS: a meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 47 | PM | 36916886 | 📋 | Immunomodulatory effects of metformin treatment in pregnant women with PCOS |
| Metformin | Polycystic Ovary Syndrome | 46 | PM | 36763111 | 📋 | Influence of metformin on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized clinical trials |
| Metformin | Polycystic Ovary Syndrome | 45 | PM | 36755918 | 📋 | Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis |
| Metformin | Polycystic Ovary Syndrome | 44 | PM | 36618831 | 📋 | The effects of melatonin and metformin on histological characteristics of the ovary and uterus in letrozole-induced polycystic ovarian syndrome mice: A stereological study |
| Metformin | Polycystic Ovary Syndrome | 43 | PM | 36351033 | 📋 | Nasturtium officinale L. and metformin alleviate the estradiol -induced polycystic ovary syndrome with synergistic effects through modulation of Bax/Bcl-2/p53/caspase-3 signaling pathway and anti-inflammatory and anti-oxidative effects |
| Metformin | Polycystic Ovary Syndrome | 42 | PM | 36322951 | 📋 | Therapeutic metformin concentrations positively regulate proliferation in endometrial epithelial cells (EECs) via mTOR activation and augmented mitochondrial strength |
| Metformin | Polycystic Ovary Syndrome | 41 | PM | 36299963 | 📋 | A Comparative Study of Luteinizing Hormone Levels in Polycystic Ovarian Syndrome With Hyperandrogenism: Metformin Versus Oral Contraceptive Pills |
| Metformin | Polycystic Ovary Syndrome | 40 | PM | 36285403 | 📋 | Effectiveness of inositol, metformin and their combination in women with PCOS undergoing assisted reproduction: systematic review and meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 39 | PM | 36225721 | 📋 | Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials |
| Metformin | Polycystic Ovary Syndrome | 38 | PM | 36176868 | 📋 | Role of Metformin in the Management of Polycystic Ovarian Syndrome-Associated Acne: A Systematic Review |
| Metformin | Polycystic Ovary Syndrome | 37 | PM | 36147577 | 📋 | Canagliflozin combined with metformin versus metformin monotherapy for endocrine and metabolic profiles in overweight and obese women with polycystic ovary syndrome: A single-center, open-labeled prospective randomized controlled trial |
| Metformin | Polycystic Ovary Syndrome | 36 | PM | 36129662 | 📋 | The Effect of Oral Antidiabetic Drugs on Improving the Endocrine and Metabolic States in Women with Polycystic Ovary Syndrome: A Systematic Review and Network Meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 35 | PM | 36062569 | 📋 | Effect of probiotics combined with metformin on improvement of menstrual and metabolic patterns in women with polycystic ovary syndrome: a randomized clinical trial |
| Metformin | Polycystic Ovary Syndrome | 34 | PM | 35893386 | 📋 | Metformin Improves the Hepatic Steatosis Index in Non-Obese Patients with Polycystic Ovary Syndrome |
| Metformin | Polycystic Ovary Syndrome | 33 | PM | 35822185 | 📋 | Combination of electroacupuncture and pharmacological treatment improves insulin resistance in women with polycystic ovary syndrome: Double-blind randomized clinical trial |
| Metformin | Polycystic Ovary Syndrome | 32 | PM | 35770635 | 📋 | [Metformin improves polycystic ovary syndrome and activates female germline stem cells in mice] |
| Metformin | Polycystic Ovary Syndrome | 31 | PM | 35748536 | 📋 | Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome |
| Metformin | Polycystic Ovary Syndrome | 30 | PM | 35621312 | 📋 | Efficacy and safety of metformin in pregnant women with polycystic ovary syndrome: a systematic review with meta-analysis of randomized and non-randomized controlled trials |
| Metformin | Polycystic Ovary Syndrome | 27 | PM | 35605922 | 📋 | Effects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome in Wistar rats |
| Metformin | Polycystic Ovary Syndrome | 15 | PM | 35535444 | 📋 | Effects of N-acetylcysteine and metformin treatment on the stereopathological characteristics of uterus and ovary |
| Metformin | Polycystic Ovary Syndrome | 12 | PM | 35501295 | 📋 | Combination of alpha lipoic acid and metformin supplement improve assisted reproductive technologies outcomes in polycystic ovary syndrome patients |
| Metformin | Polycystic Ovary Syndrome | 23 | PM | 35444350 | 📋 | Histomorphological Changes in a Rat Model of Polycystic Ovary Syndrome and the Contribution of Stevia Leaf Extract in Modulating the Ovarian Fibrosis, VEGF, and TGF-β Immunoexpressions: Comparison with Metformin |
| Metformin | Polycystic Ovary Syndrome | 25 | PM | 35363325 | 📋 | Short period-administration of myo-inositol and metformin on hormonal and glycolipid profiles in patients with polycystic ovary syndrome: a systematic review and updated meta-analysis of randomized controlled trials |
| Metformin | Polycystic Ovary Syndrome | 28 | PM | 35310326 | 📋 | Metformin effects on zonulin level in polycystic ovarian women |
| Metformin | Polycystic Ovary Syndrome | 4 | PM | 35251851 | 📋 | Study on the Effect of Berberine, Myoinositol, and Metformin in Women with Polycystic Ovary Syndrome: A Prospective Randomised Study |
| Metformin | Polycystic Ovary Syndrome | 1 | PM | 35152800 | 📋 | Apigenin exerts protective effect and restores ovarian function in dehydroepiandrosterone induced polycystic ovary syndrome rats: a biochemical and histological analysis |
| Metformin | Polycystic Ovary Syndrome | 29 | PM | 34865304 | 📋 | Gestational weight gain, appetite regulating hormones, and metformin treatment in polycystic ovary syndrome: A longitudinal, placebo-controlled study |
| Metformin | Polycystic Ovary Syndrome | 20 | PM | 34752810 | 📋 | The anti-androgenic effect of quercetin on hyperandrogenism and ovarian dysfunction induced in a dehydroepiandrosterone rat model of polycystic ovary syndrome |
| Metformin | Polycystic Ovary Syndrome | 26 | PM | 34665453 | 📋 | The effect of metformin and myoinositol on metabolic outcomes in women with polycystic ovary syndrome: role of body mass and adiponectin in a randomized controlled trial |
| Metformin | Polycystic Ovary Syndrome | 21 | PM | 34538551 | 📋 | Mechanism of quercetin on the improvement of ovulation disorder and regulation of ovarian CNP/NPR2 in PCOS model rats |
| Metformin | Polycystic Ovary Syndrome | 24 | PM | 34407851 | 📋 | Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 9 | PM | 34298098 | 📋 | Ameliorative effects of fisetin in letrozole-induced rat model of polycystic ovary syndrome |
| Metformin | Polycystic Ovary Syndrome | 10 | PM | 34286169 | 📋 | A Pilot Trial: Fish Oil and Metformin Effects on ApoB-Remnants and Triglycerides in Women With Polycystic Ovary Syndrome |
| Metformin | Polycystic Ovary Syndrome | 19 | PM | 34032731 | 📋 | Therapeutic effects of puerarin on polycystic ovary syndrome: A randomized trial in Chinese women |
| Metformin | Polycystic Ovary Syndrome | 2 | PM | 33876387 | 📋 | The Effect of Astaxanthin and Metformin on Oxidative Stress in Granulosa Cells of BALB C Mouse Model of Polycystic Ovary Syndrome |
| Metformin | Polycystic Ovary Syndrome | 8 | PM | 33861440 | 📋 | Therapeutic Effect of Curcumin in Women with Polycystic Ovary Syndrome Receiving Metformin: A Randomized Controlled Trial |
| Metformin | Polycystic Ovary Syndrome | 3 | PM | 33555077 | 📋 | Synergic effect of bee pollen and metformin on proliferation and apoptosis of granulosa cells: Rat model of polycystic ovary syndrome |
| Metformin | Polycystic Ovary Syndrome | 13 | PM | 32877649 | 📋 | The ameliorative effects of marjoram in dehydroepiandrosterone induced polycystic ovary syndrome in rats |
| Metformin | Polycystic Ovary Syndrome | 6 | PM | 31948119 | 📋 | Both Matricaria chamomilla and Metformin Extract Improved the Function and Histological Structure of Thyroid Gland in Polycystic Ovary Syndrome Rats through Antioxidant Mechanism |
| Metformin | Polycystic Ovary Syndrome | 16 | PM | 31749393 | 📋 | Comparison of the Efficacy Between NAC and Metformin in Treating PCOS Patients: A Meta-Analysis |
| Metformin | Polycystic Ovary Syndrome | 17 | PM | 30814814 | 📋 | Comparison of Metformin and N Acetylcysteine on Clinical, Metabolic Parameter and Hormonal Profile in Women With Polycystic Ovarian Syndrome |
| Metformin | Polycystic Ovary Syndrome | 5 | PM | 30538756 | 📋 | The Effect of Berberine on Polycystic Ovary Syndrome Patients With Insulin Resistance (PCOS-IR): A Meta-Analysis and Systematic Review |
| Metformin | Polycystic Ovary Syndrome | 14 | PM | 30369967 | 📋 | Effects of Moringa oleifera on Insulin Levels and Folliculogenesis in Polycystic Ovary Syndrome Model with Insulin Resistance |
| Metformin | Polycystic Ovary Syndrome | 57 | PM | 29434814 | 📋 | Metformin and pioglitazone combination therapy ameliorate polycystic ovary syndrome through AMPK/PI3K/JNK pathway |
| Metformin | Polycystic Ovary Syndrome | 54 | PM | 28941255 | 📋 | Effects of placebo-controlled insulin-sensitizing drugs on hormonal parameters in polycystic ovary syndrome patients: A network meta-analysis |
| Metformin | Polycystic Ovary Syndrome | 56 | PM | 28834135 | 📋 | The Pharmacogenetics of Metformin in Women with Polycystic Ovary Syndrome: A Randomized Trial |
| Metformin | Polycystic Ovary Syndrome | 7 | PM | 28479753 | 📋 | The Effect of Metformin and Cinnamon on Serum Anti-Mullerian Hormone in Women Having PCOS: A Double-Blind, Randomized, Controlled Trial |
| Metformin | Polycystic Ovary Syndrome | 22 | PM | 27923406 | 📋 | Ameliorative Effects of Rutin Against Metabolic, Biochemical and Hormonal Disturbances in Polycystic Ovary Syndrome in Rats |
| Metformin | Polycystic Ovary Syndrome | 18 | PM | 25482371 | 📋 | N-Acetylcysteine Improves Oocyte and Embryo Quality in Polycystic Ovary Syndrome Patients Undergoing Intracytoplasmic Sperm Injection: An Alternative to Metformin |
| Metformin | Polycystic Ovary Syndrome | 55 | PM | 24196302 | 📋 | Assessment of ovarian stromal blood flow after metformin treatment in women with polycystic ovary syndrome |
| Metformin | Polycystic Ovary Syndrome | 53 | PM | 23869585 | 📋 | The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment |
| Metformin | Polycystic Ovary Syndrome | 11 | PM | 19933994 | 📋 | Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome |
| Metformin | Thyroid Cancer | 6 | PM | 37864896 | 📋 | Integration of metabolomics and transcriptomics reveals metformin suppresses thyroid cancer progression via inhibiting glycolysis and restraining DNA replication |
| Metformin | Thyroid Cancer | 5 | PM | 37773165 | 📋 | Will metformin use lead to a decreased risk of thyroid cancer? A systematic review and meta-analyses |
| Metformin | Thyroid Cancer | 3 | PM | 36873273 | 📋 | Effect of metformin alone and in combination with etoposide and epirubicin on proliferation, apoptosis, necrosis, and migration of B-CPAP and SW cells as thyroid cancer cell lines |
| Metformin | Thyroid Cancer | 2 | PM | 36815657 | 📋 | Metformin and 2-Deoxy-d-glucose synergistically inhibit the viability of thyroid papillary carcinoma with BRAF mutation by ROS-dependent PI3K/AKT signaling pathway |
| Metformin | Thyroid Cancer | 4 | PM | 32791889 | 📋 | Metformin Reduces Thyroid Cancer Tumor Growth in the Metastatic Niche of Bone by Inhibiting Osteoblastic RANKL Productions |
| Metformin | Thyroid Cancer | 1 | PM | 28791253 | 📋 | Potential Role of Metabolic Intervention in the Management of Advanced Differentiated Thyroid Cancer |
| Metformin | Thyroid Disorders | 2 | PM | 36555150 | 📋 | Metformin Attenuates Inflammation and Fibrosis in Thyroid-Associated Ophthalmopathy |
| Metformin | Thyroid Disorders | 1 | PM | 36297423 | 📋 | Effects of Slow-Acting Metformin Treatment on the Hormonal and Morphological Thyroid Profile in Patients with Insulin Resistance |
| Metformin | Thyroid Nodules | 2 | PM | 37969194 | 📋 | Metformin ameliorates insulin resistance, thyroid nodules and thyroid function |
| Metformin | Thyroid Nodules | 1 | PM | 36297423 | 📋 | Effects of Slow-Acting Metformin Treatment on the Hormonal and Morphological Thyroid Profile in Patients with Insulin Resistance |
