| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Naringenin | Acute Liver Injury | 2 | PM | 38582338 | 📋 | Naringenin inhibits APAP-induced acute liver injury through activating PPARA-dependent signaling pathway |
| Naringenin | Acute Liver Injury | 1 | PM | 35065059 | 📋 | Naringenin affords protection against lipopolysaccharide/D-galactosamine-induced acute liver failure: Role of autophagy |
| Naringenin | Acute Pancreatitis | 2 | PM | 36713830 | 📋 | Naringenin protects against acute pancreatitis-associated intestinal injury by inhibiting NLRP3 inflammasome activation via AhR signaling |
| Naringenin | Acute Pancreatitis | 1 | PM | 29849486 | 📋 | Naringenin Protects against Acute Pancreatitis in Two Experimental Models in Mice by NLRP3 and Nrf2/HO-1 Pathways |
| Naringenin | Aging Liver | 1 | PM | 27587005 | 📋 | Citrus flavanones naringenin and hesperetin improve antioxidant status and membrane lipid compositions in the liver of old-aged Wistar rats |
| Naringenin | Colitis | 1 | PM | 30802726 | 📋 | Naringenin promotes recovery from colonic damage through suppression of epithelial tumor necrosis factor-α production and induction of M2-type macrophages in colitic mice |
| Naringenin | Colitis | 2 | PM | 26370586 | 📋 | Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents |
| Naringenin | Colon Cancer | 3 | PM | 34738632 | 📋 | Diosmin in combination with naringenin enhances apoptosis in colon cancer cells |
| Naringenin | Colon Cancer | 1 | PM | 29345053 | 📋 | Naringenin (4,5,7-trihydroxyflavanone) suppresses the development of precancerous lesions via controlling hyperproliferation and inflammation in the colon of Wistar rats |
| Naringenin | Colon Cancer | 2 | PM | 23137376 | 📋 | Multidrug resistance reversal and apoptosis induction in human colon cancer cells by some flavonoids present in citrus plants |
| Naringenin | Colorectal Cancer | 3 | PM | 38583080 | 📋 | A narrative review on therapeutic potential of naringenin in colorectal cancer: Focusing on molecular and biochemical processes |
| Naringenin | Colorectal Cancer | 2 | PM | 26157550 | 📋 | Anti-Proliferative Effect of Naringenin through p38-Dependent Downregulation of Cyclin D1 in Human Colorectal Cancer Cells |
| Naringenin | Colorectal Cancer | 1 | PM | 26074733 | 📋 | Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer |
| Naringenin | Constipation | 1 | PM | 29207043 | 📋 | Naringenin induces laxative effects by upregulating the expression levels of c-Kit and SCF, as well as those of aquaporin 3 in mice with loperamide-induced constipation |
| Naringenin | Gastric Ulcer | 1 | PM | 34769415 | 📋 | The Gastroprotective Effect of Naringenin against Ethanol-Induced Gastric Ulcers in Mice through Inhibiting Oxidative and Inflammatory Responses |
| Naringenin | Helicobacter Pylori Infection | 1 | PM | 32832762 | 📋 | Growth-Inhibiting, Bactericidal, Antibiofilm, and Urease Inhibitory Activities of Hibiscus rosa sinensis L. Flower Constituents toward Antibiotic Sensitive- and Resistant-Strains of Helicobacter pylori |
| Naringenin | Hepatic Encephalopathy | 2 | PM | 36625308 | 📋 | Naringenin mitigates thioacetamide-induced hepatic encephalopathy in rats: targeting the JNK/Bax/caspase-8 apoptotic pathway |
| Naringenin | Hepatic Encephalopathy | 1 | PM | 35289256 | 📋 | Promising effects of naringenin and melatonin against hepatic encephalopathy impairments induced by bile duct ligation in male rats |
| Naringenin | Hepatic Fibrosis | 5 | PM | 38576562 | 📋 | Naringenin alleviates liver fibrosis by triggering autophagy-dependent ferroptosis in hepatic stellate cells |
| Naringenin | Hepatic Fibrosis | 4 | PM | 36406329 | 📋 | Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway |
| Naringenin | Hepatic Fibrosis | 1 | PM | 32125927 | 📋 | Naringenin Ameliorate Carbon Tetrachloride-Induced Hepatic Damage Through Inhibition of Endoplasmic Reticulum Stress and Autophagy in Rats |
| Naringenin | Hepatic Fibrosis | 2 | PM | 31618621 | 📋 | Naringenin attenuates the progression of liver fibrosis via inactivation of hepatic stellate cells and profibrogenic pathways |
| Naringenin | Hepatic Fibrosis | 3 | PM | 28706418 | 📋 | Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways |
| Naringenin | Hepatic Steatosis | 2 | PM | 34516703 | 📋 | Does naringenin supplementation improve lipid profile, severity of hepatic steatosis and probability of liver fibrosis in overweight/obese patients with NAFLD? A randomised, double-blind, placebo-controlled, clinical trial |
| Naringenin | Hepatic Steatosis | 1 | PM | 29183361 | 📋 | Naringenin attenuates hepatitis B virus X protein-induced hepatic steatosis |
| Naringenin | Hepatitis B | 1 | PM | 29183361 | 📋 | Naringenin attenuates hepatitis B virus X protein-induced hepatic steatosis |
| Naringenin | Hepatitis C | 1 | PM | 31039496 | 📋 | Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus-infected liver |
| Naringenin | Hepatitis C | 2 | PM | 29684853 | 📋 | Naringenin improve hepatitis C virus infection induced insulin resistance by increase PTEN expression via p53-dependent manner |
| Naringenin | Hepatitis C | 3 | PM | 18393287 | 📋 | Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin |
| Naringenin | Inflammatory Bowel Disease | 2 | PM | 30301267 | 📋 | Citrus aurantium L. and Its Flavonoids Regulate TNBS-Induced Inflammatory Bowel Disease through Anti-Inflammation and Suppressing Isolated Jejunum Contraction |
| Naringenin | Inflammatory Bowel Disease | 1 | PM | 26370586 | 📋 | Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents |
| Naringenin | Intestinal Injury | 1 | PM | 36713830 | 📋 | Naringenin protects against acute pancreatitis-associated intestinal injury by inhibiting NLRP3 inflammasome activation via AhR signaling |
| Naringenin | Intestinal Permeability | 1 | PM | 33667286 | 📋 | Naringenin prevents TNF-α-induced gut-vascular barrier disruption associated with inhibiting the NF-κB-mediated MLCK/p-MLC and NLRP3 pathways |
| Naringenin | Liver Cancer | 1 | PM | 37298981 | 📋 | Naringenin Induces HepG2 Cell Apoptosis via ROS-Mediated JAK-2/STAT-3 Signaling Pathways |
| Naringenin | Liver Cancer | 2 | PM | 31665932 | 📋 | Quercetin and naringenin abate diethylnitrosamine/acetylaminofluorene-induced hepatocarcinogenesis in Wistar rats: the roles of oxidative stress, inflammation and cell apoptosis |
| Naringenin | Liver Damage | 1 | PM | 36615393 | 📋 | Naringenin Prevents Oxidative Stress and Inflammation in LPS-Induced Liver Injury through the Regulation of LncRNA-mRNA in Male Mice |
| Naringenin | Liver Damage | 2 | PM | 30324121 | 📋 | Antioxidant Potential of Naringenin Helps to Protect Liver Tissue from Streptozotocin-Induced Damage |
| Naringenin | Liver Disease | 1 | PM | 29713125 | 📋 | Beneficial effects of naringenin in liver diseases: Molecular mechanisms |
| Naringenin | MAFLD | 7 | PM | 37861538 | 📋 | Exploration of potential targets and mechanisms of naringenin in the treatment of nonalcoholic fatty liver disease through network pharmacology |
| Naringenin | MAFLD | 6 | PM | 34860705 | 📋 | Effects of naringenin supplementation on cardiovascular risk factors in overweight/obese patients with nonalcoholic fatty liver disease: a pilot double-blind, placebo-controlled, randomized clinical trial |
| Naringenin | MAFLD | 4 | PM | 34516703 | 📋 | Does naringenin supplementation improve lipid profile, severity of hepatic steatosis and probability of liver fibrosis in overweight/obese patients with NAFLD? A randomised, double-blind, placebo-controlled, clinical trial |
| Naringenin | MAFLD | 3 | PM | 34163366 | 📋 | Naringenin Attenuates Non-Alcoholic Fatty Liver Disease by Enhancing Energy Expenditure and Regulating Autophagy via AMPK |
| Naringenin | MAFLD | 5 | PM | 32879962 | 📋 | A Comprehensive Systematic Review of the Effects of Naringenin, a Citrus-Derived Flavonoid, on Risk Factors for Nonalcoholic Fatty Liver Disease |
| Naringenin | MAFLD | 2 | PM | 31758699 | 📋 | Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-κB pathway in mice |
| Naringenin | MAFLD | 1 | PM | 28718703 | 📋 | Nanoliposome improves inhibitory effects of naringenin on nonalcoholic fatty liver disease in mice |
| Naringenin | Non-Alcoholic Steatohepatitis | 2 | PM | 38107095 | 📋 | Naringenin prevents non-alcoholic steatohepatitis by modulating the host metabolome and intestinal microbiome in MCD diet-fed mice |
| Naringenin | Non-Alcoholic Steatohepatitis | 1 | PM | 33234364 | 📋 | Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe -/- mice: role of SIRT1 |
| Naringenin | Oral Cancer | 4 | PM | 35596593 | 📋 | Naringenin induces endoplasmic reticulum stress-mediated cell apoptosis and autophagy in human oral squamous cell carcinoma cells |
| Naringenin | Oral Cancer | 3 | PM | 35044489 | 📋 | Naringenin potentiates anti-tumor immunity against oral cancer by inducing lymph node CD169-positive macrophage activation and cytotoxic T cell infiltration |
| Naringenin | Oral Cancer | 1 | PM | 25256786 | 📋 | Myricetin and naringenin inhibit human squamous cell carcinoma proliferation and migration in vitro |
| Naringenin | Oral Cancer | 2 | PM | 18444138 | 📋 | Inhibition of oral carcinogenesis by citrus flavonoids |
| Naringenin | Pancreatic Cancer | 2 | PM | 31005717 | 📋 | Combined administration of naringenin and hesperetin with optimal ratio maximizes the anti-cancer effect in human pancreatic cancer via down regulation of FAK and p38 signaling pathway |
| Naringenin | Pancreatic Cancer | 1 | PM | 27838343 | 📋 | Naringenin causes ASK1-induced apoptosis via reactive oxygen species in human pancreatic cancer cells |
| Naringenin | Tongue Cancer | 1 | PM | 38178673 | 📋 | Naringenin-induced Oral Cancer Cell Apoptosis Via ROS-mediated Bid and Bcl-xl Signaling Pathway |
| Naringenin | Ulcerative Colitis | 1 | PM | 31220438 | 📋 | Flavonoids from Citrus aurantium ameliorate TNBS-induced ulcerative colitis through protecting colonic mucus layer integrity |
