| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Hydroxytyrosol | Acute Liver Injury | 1 | PM | 32572943 | 📋 | Hydroxytyrosol suppresses LPS-induced intrahepatic inflammatory responses via inhibition of ERK signaling pathway activation in acute liver injury |
| Hydroxytyrosol | Colitis | 1 | PM | 35133830 | 📋 | Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome |
| Hydroxytyrosol | Colon Cancer | 1 | PM | 29137335 | 📋 | Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells |
| Hydroxytyrosol | Colorectal Cancer | 2 | PM | 34149875 | 📋 | Discovery of hydroxytyrosol as thioredoxin reductase 1 inhibitor to induce apoptosis and G 1/S cell cycle arrest in human colorectal cancer cells via ROS generation |
| Hydroxytyrosol | Colorectal Cancer | 3 | PM | 33687886 | 📋 | A Comparison of the Anti-Cancer Effects of Free and PLGA-PAA Encapsulated Hydroxytyrosol on the HT-29 Colorectal Cancer Cell Line |
| Hydroxytyrosol | Colorectal Cancer | 1 | PM | 32943925 | 📋 | Effects of Hydroxytyrosol on Expression of Apoptotic Genes and Activity of Antioxidant Enzymes in LS180 Cells |
| Hydroxytyrosol | Colorectal Cancer | 4 | PM | 21437031 | 📋 | Effects of olive oil polyphenols on fatty acid synthase gene expression and activity in human colorectal cancer cells |
| Hydroxytyrosol | Gastrointestinal Disorders | 1 | PM | 36834520 | 📋 | Hydroxytyrosol and Its Potential Uses on Intestinal and Gastrointestinal Disease |
| Hydroxytyrosol | Helicobacter Pylori Infection | 1 | PM | 35992644 | 📋 | Extra virgin olive oil inhibits Helicobacter pylori growth in vitro and the development of mice gastric mucosa lesions in vivo |
| Hydroxytyrosol | Hepatic Fibrosis | 1 | PM | 36145170 | 📋 | Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis |
| Hydroxytyrosol | Hepatic Steatosis | 2 | PM | 30321750 | 📋 | Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2 |
| Hydroxytyrosol | Hepatic Steatosis | 1 | PM | 29747118 | 📋 | Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice |
| Hydroxytyrosol | Intestinal Permeability | 1 | PM | 35133830 | 📋 | Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome |
| Hydroxytyrosol | Liver Cancer | 1 | PM | 35229750 | 📋 | Hydroxytyrosol [2-(3,4-dihydroxyphenyl)-ethanol], a natural phenolic compound found in the olive, alters Ca 2+ signaling and viability in human HepG2 hepatoma cells |
| Hydroxytyrosol | Liver Damage | 1 | PM | 38680105 | 📋 | Hydroxytyrosol ameliorates stress-induced liver injury through activating autophagy via HDAC1/2 inhibition |
| Hydroxytyrosol | MAFLD | 1 | PM | 33060043 | 📋 | Antioxidant activity of Hydroxytyrosol and Vitamin E reduces systemic inflammation in children with paediatric NAFLD |
| Hydroxytyrosol | MAFLD | 5 | PM | 32889748 | 📋 | Quercetin and hydroxytyrosol as modulators of hepatic steatosis: A NAFLD-on-a-chip study |
| Hydroxytyrosol | MAFLD | 2 | PM | 30588836 | 📋 | The Antioxidant Effects of Hydroxytyrosol and Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease, in a Clinical Trial: A New Treatment? |
| Hydroxytyrosol | MAFLD | 3 | PM | 30057681 | 📋 | Attenuation of High-Fat Diet-Induced Rat Liver Oxidative Stress and Steatosis by Combined Hydroxytyrosol- (HT-) Eicosapentaenoic Acid Supplementation Mainly Relies on HT |
| Hydroxytyrosol | MAFLD | 4 | PM | 28386616 | 📋 | Molecular adaptations underlying the beneficial effects of hydroxytyrosol in the pathogenic alterations induced by a high-fat diet in mouse liver: PPAR-α and Nrf2 activation, and NF-κB down-regulation |
| Hydroxytyrosol | Pancreatic Cancer | 2 | PM | 34858184 | 📋 | Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor |
| Hydroxytyrosol | Pancreatic Cancer | 1 | PM | 30004416 | 📋 | The Olive Biophenols Oleuropein and Hydroxytyrosol Selectively Reduce Proliferation, Influence the Cell Cycle, and Induce Apoptosis in Pancreatic Cancer Cells |
| Hydroxytyrosol | Pancreatitis | 1 | PM | 32842687 | 📋 | Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury |
| Hydroxytyrosol | Ulcerative Colitis | 3 | PM | 35248848 | 📋 | Hydroxytyrosol alleviates dextran sodium sulfate-induced colitis by inhibiting NLRP3 inflammasome activation and modulating gut microbiota in vivo |
| Hydroxytyrosol | Ulcerative Colitis | 2 | PM | 34463261 | 📋 | Hydroxytyrosol alleviate intestinal inflammation, oxidative stress and apoptosis resulted in ulcerative colitis |
| Hydroxytyrosol | Ulcerative Colitis | 1 | PM | 27016717 | 📋 | Oleic acid, hydroxytyrosol and n-3 fatty acids collectively modulate colitis through reduction of oxidative stress and IL-8 synthesis; in vitro and in vivo studies |
