| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Hawthorn | Acute Liver Injury | 1 | PM | 30058501 | 📋 | Hepatoprotective Effects of Algerian Crataegus oxyacantha Leaves |
| Hawthorn | Colitis | 2 | PM | 34712949 | 📋 | Chemoprevention with a tea from hawthorn ( Crataegus oxyacantha) leaves and flowers attenuates colitis in rats by reducing inflammation and oxidative stress |
| Hawthorn | Colitis | 1 | PM | 33774071 | 📋 | Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism |
| Hawthorn | Colorectal Cancer | 2 | PM | 36686366 | 📋 | Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells |
| Hawthorn | Colorectal Cancer | 1 | PM | 26495895 | 📋 | Crataegus azarolus Leaves Induce Antiproliferative Activity, Cell Cycle Arrest, and Apoptosis in Human HT-29 and HCT-116 Colorectal Cancer Cells |
| Hawthorn | Diarrhea | 1 | PM | 33320393 | 📋 | Protective effects of Crataegus azarolus L. berries aqueous extract against castor oil-induced diarrhea, oxidative stress, and inflammation in rat |
| Hawthorn | Dysbiosis | 1 | PM | 36425260 | 📋 | The Hypolipidemic Effect of Hawthorn Leaf Flavonoids through Modulating Lipid Metabolism and Gut Microbiota in Hyperlipidemic Rats |
| Hawthorn | Dyspepsia | 1 | PM | 33476053 | 📋 | LC-MS based plasma metabolomics study of the intervention effect of different polar parts of Hawthorn on gastrointestinal motility disorder rats |
| Hawthorn | Functional Dyspepsia | 1 | PM | 34710267 | 📋 | Digestion-Promoting Effects and Mechanisms of Dashanzha Pill Based on Raw and Charred Crataegi Fructus |
| Hawthorn | Gastric Ulcer | 1 | PM | 18698794 | 📋 | Anti-inflammatory, gastroprotective, free-radical-scavenging, and antimicrobial activities of hawthorn berries ethanol extract |
| Hawthorn | Gastrointestinal Cancer | 1 | PM | 38327605 | 📋 | Effect of Shan Zha (Hawthorn or Crataegus) on gastrointestinal cancer: A network pharmacology and molecular docking study |
| Hawthorn | Hepatic Fibrosis | 1 | PM | 33255507 | 📋 | Hawthorn Herbal Preparation from Crataegus oxyacantha Attenuates In Vivo Carbon Tetrachloride -Induced Hepatic Fibrosis via Modulating Oxidative Stress and Inflammation |
| Hawthorn | Hepatic Steatosis | 1 | PM | 34585409 | 📋 | Crataegus aronia prevents high-fat diet-induced hepatic steatosis in rats by activating AMPK-induced suppression of SREBP1 and activation of PPARα |
| Hawthorn | Hepatic Steatosis | 2 | PM | 24626737 | 📋 | A diet formula of Puerariae radix, Lycium barbarum, Crataegus pinnatifida, and Polygonati rhizoma alleviates insulin resistance and hepatic steatosis in CD-1 mice and HepG2 cells |
| Hawthorn | Inflammatory Bowel Disease | 1 | PM | 33774071 | 📋 | Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism |
| Hawthorn | Liver Cancer | 1 | PM | 29534982 | 📋 | Phenylpropanoids from the fruit of Crataegus pinnatifida exhibit cytotoxicity on hepatic carcinoma cells through apoptosis induction |
| Hawthorn | Liver Disease | 1 | PM | 35215517 | 📋 | Potential Roles and Key Mechanisms of Hawthorn Extract against Various Liver Diseases |
| Hawthorn | MAFLD | 6 | PM | 38601914 | 📋 | A study on the treatment effects of Crataegus pinnatifida polysaccharide on non-alcoholic fatty liver in mice by modulating gut microbiota |
| Hawthorn | MAFLD | 5 | PM | 34585409 | 📋 | Crataegus aronia prevents high-fat diet-induced hepatic steatosis in rats by activating AMPK-induced suppression of SREBP1 and activation of PPARα |
| Hawthorn | MAFLD | 1 | PM | 33435558 | 📋 | Protective Effects of Polyphenol Enriched Complex Plants Extract on Metabolic Dysfunctions Associated with Obesity and Related Nonalcoholic Fatty Liver Diseases in High Fat Diet-Induced C57BL/6 Mice |
| Hawthorn | MAFLD | 4 | PM | 30375253 | 📋 | Crataegus aronia enhances sperm parameters and preserves testicular architecture in both control and non-alcoholic fatty liver disease-induced rats |
| Hawthorn | MAFLD | 3 | PM | 29719880 | 📋 | Ethanol Extract of Crataegus Oxyacantha L. Ameliorate Dietary Non-Alcoholic Fatty Liver Disease in Rat |
| Hawthorn | MAFLD | 2 | PM | 27424611 | 📋 | Protective and therapeutic effects of Crataegus aronia in non-alcoholic fatty liver disease |
