| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Calycosin | Acute Liver Failure | 1 | PM | 37506138 | 📋 | Calycosin inhibits hepatocyte apoptosis in acute liver failure by suppressing the TLR4/NF-κB pathway: An in vitro study |
| Calycosin | Acute Pancreatitis | 1 | PM | 34908806 | 📋 | Calycosin attenuates severe acute pancreatitis-associated acute lung injury by curtailing high mobility group box 1 - induced inflammation |
| Calycosin | Acute Pancreatitis | 2 | PM | 29890468 | 📋 | Calycosin alleviates cerulein-induced acute pancreatitis by inhibiting the inflammatory response and oxidative stress via the p38 MAPK and NF-κB signal pathways in mice |
| Calycosin | Colon Cancer | 1 | PM | 36755950 | 📋 | Uncovering the effects and molecular mechanism of Astragalus membranaceus (Fisch.) Bunge and its bioactive ingredients formononetin and calycosin against colon cancer: An integrated approach based on network pharmacology analysis coupled with experimental validation and molecular docking |
| Calycosin | Colorectal Cancer | 1 | PM | 35842774 | 📋 | Calycosin suppresses colorectal cancer progression by targeting ERβ, upregulating PTEN, and inhibiting PI3K/Akt signal pathway |
| Calycosin | Colorectal Cancer | 2 | PM | 27393650 | 📋 | Calycosin induces apoptosis in colorectal cancer cells, through modulating the ERβ/MiR-95 and IGF-1R, PI3K/Akt signaling pathways |
| Calycosin | Gastric Cancer | 1 | PM | 33883905 | 📋 | Calycosin Induces Gastric Cancer Cell Apoptosis via the ROS-Mediated MAPK/STAT3/NF-κB Pathway |
| Calycosin | Hepatic Fibrosis | 2 | PM | 36207725 | 📋 | Overexpression of estrogen receptor β inhibits cellular functions of human hepatic stellate cells and promotes the anti-fibrosis effect of calycosin via inhibiting STAT3 phosphorylation |
| Calycosin | Hepatic Fibrosis | 1 | PM | 32474674 | 📋 | Hepatoprotective effect and possible mechanism of phytoestrogen calycosin on carbon tetrachloride-induced liver fibrosis in mice |
| Calycosin | Hepatic Fibrosis | 3 | PM | 28190475 | 📋 | Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor |
| Calycosin | Hepatic Steatosis | 1 | PM | 35490724 | 📋 | Calycosin-7-O-β-D-glucoside attenuates palmitate-induced lipid accumulation in hepatocytes through AMPK activation |
| Calycosin | Intestinal Permeability | 1 | PM | 35795283 | 📋 | Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress |
| Calycosin | Liver Cancer | 2 | PM | 34186122 | 📋 | Enhancement of interferon gamma stability as an anticancer therapeutic protein against hepatocellular carcinoma upon interaction with calycosin |
| Calycosin | Liver Cancer | 1 | PM | 33188878 | 📋 | Calycosin induces mitochondrial-dependent apoptosis and cell cycle arrest, and inhibits cell migration through a ROS-mediated signaling pathway in HepG2 hepatocellular carcinoma cells |
| Calycosin | Non-Alcoholic Steatohepatitis | 1 | PM | 28190475 | 📋 | Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor |
| Calycosin | Pancreatic Cancer | 1 | PM | 35968328 | 📋 | MUC1 is responsible for the pro-metastatic potential of calycosin in pancreatic ductal adenocarcinoma |
