| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Bromelain | Acute Liver Injury | 1 | PM | 36227279 | 📋 | Bromelain ameliorates D-galactosamine-induced acute liver injury: role of SIRT1/LKB1/AMPK, GSK3β/Nrf2 and NF-κB p65/TNF-α/caspase-8, -9 signalling pathways |
| Bromelain | Biliary Tract Cancer | 1 | PM | 26935541 | 📋 | Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines |
| Bromelain | Celiac Disease | 1 | PM | 37803248 | 📋 | Bromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells |
| Bromelain | Colitis | 1 | PM | 20848493 | 📋 | Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis |
| Bromelain | Colon Cancer | 1 | PM | 36837502 | 📋 | ACE2-Inhibitory Effects of Bromelain and Ficin in Colon Cancer Cells |
| Bromelain | Colon Cancer | 2 | PM | 23620673 | 📋 | Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21) |
| Bromelain | Colorectal Cancer | 4 | PM | 37262048 | 📋 | Cytotoxic properties of unfractionated and fractionated bromelain alone or in combination with chemotherapeutic agents in colorectal cancer cells |
| Bromelain | Colorectal Cancer | 3 | PM | 34094682 | 📋 | Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T |
| Bromelain | Colorectal Cancer | 2 | PM | 30657763 | 📋 | Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy |
| Bromelain | Colorectal Cancer | 1 | PM | 30460115 | 📋 | Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis |
| Bromelain | Colorectal Cancer | 5 | PM | 24123777 | 📋 | The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects |
| Bromelain | Food Poisoning | 1 | PM | 35893899 | 📋 | Exploring the Binding Interaction of Active Compound of Pineapple against Foodborne Bacteria and Novel Coronavirus (SARS-CoV-2) Based on Molecular Docking and Simulation Studies |
| Bromelain | Gastric Cancer | 1 | PM | 23620673 | 📋 | Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21) |
| Bromelain | Gastrointestinal Cancer | 1 | PM | 25425315 | 📋 | Bromelain and N-acetylcysteine Inhibit Proliferation and Survival of Gastrointestinal Cancer Cells in Vitro: Significance of Combination Therapy |
| Bromelain | Hepatic Fibrosis | 1 | PM | 37269556 | 📋 | Bromelain mitigates liver fibrosis via targeting hepatic stellate cells in vitro and in vivo |
| Bromelain | Inflammatory Bowel Disease | 1 | PM | 34387509 | 📋 | Anti-inflammatory properties of a proprietary bromelain extract (Bromeyal™) after in vitro simulated gastrointestinal digestion |
| Bromelain | Inflammatory Bowel Disease | 2 | PM | 20848493 | 📋 | Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis |
| Bromelain | Intestinal Injury | 1 | PM | 37692988 | 📋 | Therapeutic effect of bromelain and papain on intestinal injury induced by indomethacin in male rats |
| Bromelain | Intestinal Spasm | 1 | PM | 21689210 | 📋 | Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice |
| Bromelain | Liver Cancer | 2 | PM | 33735410 | 📋 | Cytotoxic Effect of Bromelain on HepG2 Hepatocellular Carcinoma Cell Line |
| Bromelain | Liver Cancer | 1 | PM | 33312377 | 📋 | Enhancing the potency of chemotherapeutic agents by combination with bromelain and N-acetylcysteine - an in vitro study with pancreatic and hepatic cancer cells |
| Bromelain | MAFLD | 3 | PM | 35684129 | 📋 | New Mechanisms of Bromelain in Alleviating Non-Alcoholic Fatty Liver Disease-Induced Deregulation of Blood Coagulation |
| Bromelain | MAFLD | 2 | PM | 32531862 | 📋 | Bromelain Reduces the Non-Alcoholic Fatty Liver Disease and Periodontal Damages Caused by Ligature-Induced Periodontitis |
| Bromelain | MAFLD | 1 | PM | 32443556 | 📋 | Bromelain Confers Protection Against the Non-Alcoholic Fatty Liver Disease in Male C57bl/6 Mice |
| Bromelain | Oral and Dental Health | 1 | PM | 21356017 | 📋 | Stain removal efficacy of a novel dentifrice containing papain and Bromelain extracts--an in vitro study |
| Bromelain | Oral Cancer | 1 | PM | 31139378 | 📋 | The potential use of bromelain as a natural oral medicine having anticarcinogenic activities |
| Bromelain | Pancreatic Cancer | 1 | PM | 33312377 | 📋 | Enhancing the potency of chemotherapeutic agents by combination with bromelain and N-acetylcysteine - an in vitro study with pancreatic and hepatic cancer cells |
| Bromelain | Peritoneal Adhesions | 1 | PM | 25573606 | 📋 | Bromelain: a natural proteolytic for intra-abdominal adhesion prevention |
