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List of Berberine and group Digestive System intersectionsRows: 354■ Human ■ Animal ■ Risk ■ Review

SubstanceConditionSeqSrc
PMID
Dtl
Title
Berberine Acute Liver Failure
1
PM
29191769📋Berberine protects acute liver failure in mice through inhibiting inflammation and mitochondria-dependent apoptosis
Berberine Acute Liver Injury
1
PM
31432116📋Berberine Ameliorates CCl4‑induced Liver Injury in Rats Through Regulation of the Nrf2‑Keap1‑ARE and p53 Signaling Pathways
Berberine Acute Pancreatitis
1
PM
30066867📋Cognitive Impairments Induced by Severe Acute Pancreatitis Are Attenuated by Berberine Treatment in Rats
Berberine Acute Pancreatitis
2
PM
28797013📋Effects of Berberine on Acute Necrotizing Pancreatitis and Associated Lung Injury
Berberine Acute Pancreatitis
3
PM
27148818📋Berberine Inhibits Inflammatory Mediators and Attenuates Acute Pancreatitis Through Deactivation of JNK Signaling Pathways
Berberine Atrophic Gastritis
1
PM
34265298📋Therapeutic effect of berberine on chronic atrophic gastritis based on plasma and urine metabolisms
Berberine Atrophic Gastritis
2
PM
33841162📋Berberine Attenuates Chronic Atrophic Gastritis Induced by MNNG and Its Potential Mechanism
Berberine Atrophic Gastritis
3
PM
33340526📋Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis
Berberine Atrophic Gastritis
4
PM
32097666📋Mechanism of Berberine in Treating Helicobacter Pylori Induced Chronic Atrophic Gastritis Through IRF8-IFN-γ Signaling Axis Suppressing
Berberine Autoimmune Hepatitis
2
PM
38466881📋Berberine alleviates concanavalin A-induced autoimmune hepatitis in mice by modulating the gut microbiota
Berberine Autoimmune Hepatitis
1
PM
29283990📋The Effects of Berberine on Concanavalin A-Induced Autoimmune Hepatitis (AIH) in Mice and the Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase (AMPK) Pathway
Berberine Biliary Tract Cancer
2
PM
36308362📋Low Dose Berberine Suppresses Cholangiocarcinoma Cell Progression as a Multi-Kinase Inhibitor
Berberine Biliary Tract Cancer
1
PM
28566619📋Berberine Induces Cell Cycle Arrest in Cholangiocarcinoma Cell Lines via Inhibition of NF-κB and STAT3 Pathways
Berberine Colitis
16
PM
36528592📋Berberine increases stromal production of Wnt molecules and activates Lgr5+ stem cells to promote epithelial restitution in experimental colitis
Berberine Colitis
15
PM
35980327📋A Combination of Baicalin and Berberine Hydrochloride Ameliorates Dextran Sulfate Sodium-Induced Colitis by Modulating Colon Gut Microbiota
Berberine Colitis
14
PM
35259053📋Berberine represses Wnt/β-catenin pathway activation via modulating the microRNA-103a-3p/Bromodomain-containing protein 4 axis, thereby refraining pyroptosis and reducing the intestinal mucosal barrier defect induced via colitis
Berberine Colitis
10
PM
33285228📋Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites
Berberine Colitis
9
PM
33061833📋Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways
Berberine Colitis
8
PM
32800336📋Regulation of MFN2 by berberine alleviates obesity exacerbated colitis
Berberine Colitis
13
PM
32564751📋Berberine Administration in Treatment of Colitis: A Review
Berberine Colitis
7
PM
32483416📋Rescuing Dicer Expression in Inflamed Colon Tissues Alleviates Colitis and Prevents Colitis-Associated Tumorigenesis
Berberine Colitis
18
PM
31866303📋Circadian pharmacological effects of berberine on chronic colitis in mice: Role of the clock component Rev-erbα
Berberine Colitis
6
PM
31417110📋Berberine Improved Experimental Chronic Colitis by Regulating Interferon-γ- And IL-17A-producing Lamina Propria CD4 + T Cells Through AMPK Activation
Berberine Colitis
4
PM
31354497📋Berberine Protects Mice Against Dextran Sulfate Sodium-Induced Colitis by Activating mTORC1 Pathway
Berberine Colitis
5
PM
29891588📋Berberine Upregulates P-Glycoprotein in Human Caco-2 Cells and in an Experimental Model of Colitis in the Rat via Activation of Nrf2-Dependent Mechanisms
Berberine Colitis
3
PM
29482156📋Berberine Inhibits Macrophage M1 Polarization via AKT1/SOCS1/NF-κB Signaling Pathway to Protect Against DSS-induced Colitis
Berberine Colitis
2
PM
28759012📋Berberine Inhibits Colitis-Associated Tumorigenesis via Suppressing Inflammatory Responses and the Consequent EGFR Signaling-Involved Tumor Cell Growth
Berberine Colitis
1
PM
28587416📋Berberine Alleviates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress
Berberine Colitis
12
PM
24363687📋Comparative Study of Berberis vulgaris Fruit Extract and Berberine Chloride Effects on Acetic Acid-Induced Colitis in Rats
Berberine Colitis
17
PM
22173918📋Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice
Berberine Colitis
11
PM
20828550📋Berberine ameliorates TNBS-induced colitis by inhibiting lipid peroxidation, enterobacterial growth and NF-κB activation
Berberine Colon Cancer
24
PM
38312643📋Berberine improved the microbiota in lung tissue of colon cancer and reversed the bronchial epithelial cell changes caused by cancer cells
Berberine Colon Cancer
23
PM
38020547📋Study on the mechanism of action of effective monomeric, berberine of Xianglian Pill in inhibiting human colon cancer cells based on fatty acid synthase target
Berberine Colon Cancer
22
PM
37639199📋Suppression of colon cancer growth by berberine mediated by the intestinal microbiota and the suppression of DNA methyltransferases (DNMTs)
Berberine Colon Cancer
17
PM
37175233📋Berberine Inhibited Growth and Migration of Human Colon Cancer Cell Lines by Increasing Phosphatase and Tensin and Inhibiting Aquaporins 1, 3 and 5 Expressions
Berberine Colon Cancer
16
PM
35837174📋c-MYC and HIF1α promoter G-quadruplexes dependent metabolic regulation mechanism of berberine in colon cancer
Berberine Colon Cancer
15
PM
35641094📋Berberine suppresses the migration and invasion of colon cancer cells by inhibition of lipogenesis through modulation of promyelocytic leukemia zinc finger-mediated sterol-regulatory element binding proteins cleavage-activating protein ubiquitination
Berberine Colon Cancer
14
PM
35572672📋Suppression of Berberine and Probiotics ( in vitro and in vivo) on the Growth of Colon Cancer With Modulation of Gut Microbiota and Butyrate Production
Berberine Colon Cancer
13
PM
35063579📋β-catenin correlates with the progression of colon cancers and berberine inhibits the proliferation of colon cancer cells by regulating the β-catenin signaling pathway
Berberine Colon Cancer
12
PM
34028068📋Demethyleneberberine promotes apoptosis and suppresses TGF-β/Smads induced EMT in the colon cancer cells HCT-116
Berberine Colon Cancer
11
PM
33806918📋Quantitative Proteomics Analysis of Berberine-Treated Colon Cancer Cells Reveals Potential Therapy Targets
Berberine Colon Cancer
10
PM
33417512📋Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells
Berberine Colon Cancer
9
PM
32483416📋Rescuing Dicer Expression in Inflamed Colon Tissues Alleviates Colitis and Prevents Colitis-Associated Tumorigenesis
Berberine Colon Cancer
2
PM
31874145📋Berberine Suppresses Colon Cancer Cell Proliferation by Inhibiting the SCAP/SREBP-1 Signaling Pathway-Mediated Lipogenesis
Berberine Colon Cancer
4
PM
31663444📋Berberine and Tinospora cordifolia Exert a Potential Anticancer Effect on Colon Cancer Cells by Acting on Specific Pathways
Berberine Colon Cancer
6
PM
30536375📋Berberine Reversed the Epithelial-Mesenchymal Transition of Normal Colonic Epithelial Cells Induced by SW480 Cells Through Regulating the Important Components in the TGF-β Pathway
Berberine Colon Cancer
20
PM
30195873📋Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway
Berberine Colon Cancer
8
PM
29938466📋Potential Prophylactic Effect of Berberine Against Rat Colon Carcinoma Induce by 1,2-Dimethyl Hydrazine
Berberine Colon Cancer
5
PM
29565467📋Berberine Decelerates Glucose Metabolism via Suppression of mTOR‑dependent HIF‑1α Protein Synthesis in Colon Cancer Cells
Berberine Colon Cancer
7
PM
28846104📋Berberine Binds RXRα to Suppress β-Catenin Signaling in Colon Cancer Cells
Berberine Colon Cancer
19
PM
24173769📋Berberine enhances chemosensitivity to irinotecan in colon cancer via inhibition of NF‑κB
Berberine Colon Cancer
18
PM
24015932📋Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling
Berberine Colon Cancer
3
PM
22469784📋Berberine Inhibits the Proliferation of Colon Cancer Cells by Inactivating Wnt/β-catenin Signaling
Berberine Colon Cancer
21
PM
21747769📋Berberine Reduces cAMP-Induced Chloride Secretion in T84 Human Colonic Carcinoma Cells through Inhibition of Basolateral KCNQ1 Channels
Berberine Colon Cancer
1
PM
21246838📋[Preventive Effects of Berberine on Experimental Colon Cancer and Relationship With cyclooxygenase-2 Expression]
Berberine Colorectal Cancer
39
PM
38742849📋Berberine: Potential preventive and therapeutic strategies for human colorectal cancer
Berberine Colorectal Cancer
38
PM
38049785📋Identification of FtfL as a novel target of berberine in intestinal bacteria
Berberine Colorectal Cancer
37
PM
37757496📋Berberine: An inspiring resource for the treatment of colorectal diseases
Berberine Colorectal Cancer
36
PM
37553874📋Berberine might block colorectal carcinogenesis by inhibiting the regulation of B-cell function by Veillonella parvula
Berberine Colorectal Cancer
35
PM
37404762📋Liquid chromatography-tandem mass spectrometry analysis of a ratio-optimized drug pair of Sophora flavescens Aiton and Coptis chinensis Franch and study on the mechanism of anti-colorectal cancer effect of two alkaloids thereof
Berberine Colorectal Cancer
32
PM
37151876📋Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine
Berberine Colorectal Cancer
31
PM
37059377📋Berberine induces SOCS1 pathway to reprogram the M1 polarization of macrophages via miR-155-5p in colitis-associated colorectal cancer
Berberine Colorectal Cancer
30
PM
37028248📋Berberine is a suppressor of Hedgehog signaling cascade in colorectal cancer
Berberine Colorectal Cancer
29
PM
36822301📋Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells
Berberine Colorectal Cancer
28
PM
36394793📋Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells
Berberine Colorectal Cancer
27
PM
36130331📋Berberine inhibits tumour growth in vivo and in vitro through suppressing the lincROR-Wnt/β-catenin regulatory axis in colorectal cancer
Berberine Colorectal Cancer
26
PM
35992091📋Chemoproteomics reveals berberine directly binds to PKM2 to inhibit the progression of colorectal cancer
Berberine Colorectal Cancer
25
PM
35802997📋Berberine inhibited the formation of metastasis by intervening the secondary homing of colorectal cancer cells in the blood circulation to the lung and liver through HEY2
Berberine Colorectal Cancer
24
PM
35679795📋Berberine suppresses colorectal cancer by regulation of Hedgehog signaling pathway activity and gut microbiota
Berberine Colorectal Cancer
23
PM
35660350📋Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora
Berberine Colorectal Cancer
22
PM
35600365📋Berberine and Oligomeric Proanthocyanidins Exhibit Synergistic Efficacy Through Regulation of PI3K-Akt Signaling Pathway in Colorectal Cancer
Berberine Colorectal Cancer
21
PM
35596224📋Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota
Berberine Colorectal Cancer
20
PM
35572960📋Berberine as a Potential Agent for the Treatment of Colorectal Cancer
Berberine Colorectal Cancer
19
PM
35337060📋A Combined Treatment with Berberine and Andrographis Exhibits Enhanced Anti-Cancer Activity through Suppression of DNA Replication in Colorectal Cancer
Berberine Colorectal Cancer
16
PM
35215376📋Pre-Administration of Berberine Exerts Chemopreventive Effects in AOM/DSS-Induced Colitis-Associated Carcinogenesis Mice via Modulating Inflammation and Intestinal Microbiota
Berberine Colorectal Cancer
18
PM
34869024📋Berberine Suppresses Stemness and Tumorigenicity of Colorectal Cancer Stem-Like Cells by Inhibiting m 6 A Methylation
Berberine Colorectal Cancer
17
PM
34509605📋Efficacy and safety of berberine in preventing recurrence of colorectal adenomas: A systematic review and meta-analysis
Berberine Colorectal Cancer
14
PM
33450878📋Berberine Inhibits Telomerase Activity and Induces Cell Cycle Arrest and Telomere Erosion in Colorectal Cancer Cell Line, HCT 116
Berberine Colorectal Cancer
13
PM
33072135📋A Holistic View of Berberine Inhibiting Intestinal Carcinogenesis in Conventional Mice Based on Microbiome-Metabolomics Analysis
Berberine Colorectal Cancer
12
PM
32958873📋Berberine inhibits colorectal tumor growth by suppressing SHH secretion
Berberine Colorectal Cancer
11
PM
32926933📋Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3
Berberine Colorectal Cancer
10
PM
32109457📋Combined Effects of Berberine and Evodiamine on Colorectal Cancer Cells and Cardiomyocytes in Vitro
Berberine Colorectal Cancer
1
PM
31926918📋Berberine Versus Placebo for the Prevention of Recurrence of Colorectal Adenoma: A Multicentre, Double-Blinded, Randomised Controlled Study
Berberine Colorectal Cancer
9
PM
31743135📋Berberine Inhibits Proliferation and Migration of Colorectal Cancer Cells by Downregulation of GRP78
Berberine Colorectal Cancer
15
PM
31173223📋Long non‑coding RNA CASC2 enhances berberine‑induced cytotoxicity in colorectal cancer cells by silencing BCL2
Berberine Colorectal Cancer
6
PM
30257361📋Effects of Berberine on Tumor Growth and Intestinal Permeability in HCT116 Tumor-Bearing Mice Using Polyamines as Targets
Berberine Colorectal Cancer
7
PM
30205580📋The Effects of Berberine on the Gut Microbiota in Apc min/+ Mice Fed With a High Fat Diet
Berberine Colorectal Cancer
5
PM
28759012📋Berberine Inhibits Colitis-Associated Tumorigenesis via Suppressing Inflammatory Responses and the Consequent EGFR Signaling-Involved Tumor Cell Growth
Berberine Colorectal Cancer
3
PM
28098901📋Effect of Evodiamine and Berberine on the Interaction Between DNMTs and Target microRNAs During Malignant Transformation of the Colon by TGF-β1
Berberine Colorectal Cancer
4
PM
27493671📋Berberine Inhibits Intestinal Polyps Growth in Apc (Min/+) Mice via Regulation of Macrophage Polarization
Berberine Colorectal Cancer
8
PM
26463023📋[Effect and Mechanism of EGFR Expression in Macrophages on the Anti-Cancer Effect of Berberine on Colorectal Cancer]
Berberine Colorectal Cancer
2
PM
25954974📋Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway
Berberine Colorectal Cancer
33
PM
23604974📋Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo
Berberine Colorectal Cancer
34
PM
22193446📋[Berberine activates volume-sensitive chloride channel in human colorectal carcinoma cells]
Berberine Diarrhea
3
PM
33149763📋Berberine for diarrhea in children and adults: a systematic review and meta-analysis
Berberine Diarrhea
2
PM
32283882📋Role of a Berberine-Based Nutritional Supplement in Reducing Diarrhea in Subjects With Functional Gastrointestinal Disorders
Berberine Diarrhea
1
PM
19243699📋The Effect of Berberine in Vitro on Tight Junctions in Human Caco-2 Intestinal Epithelial Cells
Berberine Diarrhea
4
PM
3935203📋Clinical trial of berberine in acute watery diarrhoea
Berberine Dysbiosis
21
PM
37599699📋Berberine influences multiple diseases by modifying gut microbiota
Berberine Dysbiosis
20
PM
36465656📋Multi-target regulation of intestinal microbiota by berberine to improve type 2 diabetes mellitus
Berberine Dysbiosis
19
PM
35721198📋Modulation of Gut Microbiota and Metabolites by Berberine in Treating Mice With Disturbances in Glucose and Lipid Metabolism
Berberine Dysbiosis
18
PM
35611943📋Responses of human gut microbiota abundance and amino acid metabolism in vitro to berberine
Berberine Dysbiosis
17
PM
35499044📋Gut microbiota specifically mediates the anti-hypercholesterolemic effect of berberine (BBR) and facilitates to predict BBR's cholesterol-decreasing efficacy in patients
Berberine Dysbiosis
16
PM
35082799📋The Potential Prebiotic Berberine Combined With Methimazole Improved the Therapeutic Effect of Graves' Disease Patients Through Regulating the Intestinal Microbiome
Berberine Dysbiosis
15
PM
34984827📋Berberine ameliorates aGVHD by gut microbiota remodelling, TLR4 signalling suppression and colonic barrier repairment for NLRP3 inflammasome inhibition
Berberine Dysbiosis
14
PM
34921647📋Anti-obesity and Gut Microbiota Modulation Effect of Astragalus Polysaccharides Combined with Berberine on High-Fat Diet-Fed Obese Mice
Berberine Dysbiosis
13
PM
34480937📋Berberine combined with stachyose improves glycometabolism and gut microbiota through regulating colonic microRNA and gene expression in diabetic rats
Berberine Dysbiosis
12
PM
34365978📋Effectiveness and safety of Bifidobacterium and berberine in human hyperglycemia and their regulatory effect on the gut microbiota: a multi-center, double-blind, randomized, parallel-controlled study
Berberine Dysbiosis
11
PM
34025574📋Berberine Slows the Progression of Prediabetes to Diabetes in Zucker Diabetic Fatty Rats by Enhancing Intestinal Secretion of Glucagon-Like Peptide-2 and Improving the Gut Microbiota
Berberine Dysbiosis
10
PM
33923174📋Prebiotic Effect of Berberine and Curcumin Is Associated with the Improvement of Obesity in Mice
Berberine Dysbiosis
9
PM
33716449📋Effect of berberine on hyperglycaemia and gut microbiota composition in type 2 diabetic Goto-Kakizaki rats
Berberine Dysbiosis
8
PM
33680978📋Effects of Berberine on the Gastrointestinal Microbiota
Berberine Dysbiosis
7
PM
33623004📋Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson's disease by regulating gut microbiota
Berberine Dysbiosis
6
PM
33558654📋Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation
Berberine Dysbiosis
5
PM
33493658📋Berberine ameliorates ovariectomy-induced anxiety-like behaviors by enrichment in equol generating gut microbiota
Berberine Dysbiosis
4
PM
33430766📋Berberine alters gut microbial function through modulation of bile acids
Berberine Dysbiosis
3
PM
33359679📋Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota Are Attributable to Its Key Ingredient Berberine
Berberine Dysbiosis
2
PM
32937246📋Berberine alleviates type 2 diabetic symptoms by altering gut microbiota and reducing aromatic amino acids
Berberine Dysbiosis
1
PM
32231564📋Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE-/- Mice
Berberine Esophageal Cancer
1
PM
28465635📋Berberine Displays Antitumor Activity in Esophageal Cancer Cells in vitro
Berberine Esophageal Cancer
2
PM
27876206📋Synergistic anti-cancer effects of galangin and berberine through apoptosis induction and proliferation inhibition in oesophageal carcinoma cells
Berberine Esophageal Cancer
4
PM
26667771📋Role of Berberine on molecular markers involved in migration of esophageal cancer cells
Berberine Esophageal Cancer
3
PM
24025355📋Berberine enhances radiosensitivity of esophageal squamous cancer by targeting HIF-1α in vitro and in vivo
Berberine Familial Adenomatous Polyposis
1
PM
27493671📋Berberine Inhibits Intestinal Polyps Growth in Apc (Min/+) Mice via Regulation of Macrophage Polarization
Berberine Familial Adenomatous Polyposis
2
PM
24015932📋Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling
Berberine Gastric Cancer
13
PM
36108874📋Berberine for gastric cancer prevention and treatment: Multi-step actions on the Correa's cascade underlie its therapeutic effects
Berberine Gastric Cancer
12
PM
35582103📋Berberine retarded the growth of gastric cancer xenograft tumors by targeting hepatocyte nuclear factor 4α
Berberine Gastric Cancer
11
PM
35341784📋Combination of berberine and low glucose inhibits gastric cancer through the PP2A/GSK3β/MCL-1 signaling pathway
Berberine Gastric Cancer
10
PM
34968467📋Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6
Berberine Gastric Cancer
9
PM
34712379📋Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGF β R Regulating TGF- β/Smad Pathway
Berberine Gastric Cancer
8
PM
34055022📋Effects of Berberine on Circular RNA Expression Profiles in Human Gastric Cancer Cells
Berberine Gastric Cancer
7
PM
33362566📋Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer
Berberine Gastric Cancer
6
PM
32454290📋Berberine Represses Human Gastric Cancer Cell Growth in Vitro and in Vivo by Inducing Cytostatic Autophagy via Inhibition of MAPK/mTOR/p70S6K and Akt Signaling Pathways
Berberine Gastric Cancer
5
PM
32328135📋Berberine Suppressed Tumor Growth Through Regulating Fatty Acid Metabolism and Triggering Cell Apoptosis via Targeting FABPs
Berberine Gastric Cancer
4
PM
32277648📋Berberine Inhibits Human Gastric Cancer Cell Growth via Deactivation of p38/JNK Pathway, Induction of Mitochondrial-Mediated Apoptosis, Caspase Activation and NF-κB Inhibition
Berberine Gastric Cancer
2
PM
27142767📋Berberine Modulates Cisplatin Sensitivity of Human Gastric Cancer Cells by Upregulation of miR-203
Berberine Gastric Cancer
1
PM
26492225📋Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil
Berberine Gastric Cancer
3
PM
25045784📋Synergistic Inhibitory Effect of Berberine and D-Limonene on Human Gastric Carcinoma Cell Line MGC803
Berberine Gastric Cancer
14
PM
24063987📋Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine
Berberine Gastric Ulcer
1
PM
38193042📋Protective Effect of Berberine on Acute Gastric Ulcer by Promotion of Tricarboxylic Acid Cycle-Mediated Arachidonic Acid Metabolism
Berberine Gastritis
1
PM
29345340📋Berberine Demonstrates Anti-Inflammatory Properties in Helicobacter Pylori-Infected Mice With Chronic Gastritis by Attenuating the Th17 Response Triggered by the B Cell-Activating Factor
Berberine Gastrointestinal Cancer
4
PM
37047563📋Berberine Induces Combined Cell Death in Gastrointestinal Cell Lines
Berberine Gastrointestinal Cancer
3
PM
36915942📋The therapeutic effects of berberine for gastrointestinal cancers
Berberine Gastrointestinal Cancer
2
PM
33130557📋Berberine represses β-catenin translation involving 4E-BPs in hepatocellular carcinoma cells
Berberine Gastrointestinal Cancer
1
PM
30125974📋Berberine: A Potential Adjunct for the Treatment of Gastrointestinal Cancers?
Berberine Gastrointestinal Cancer
5
PM
24279644📋Chemopreventive effects of berberine on intestinal tumor development in Apcmin/+ mice
Berberine Gastroparesis
1
PM
37026044📋Berberine ameliorates the neurological dysfunction of the gastric fundus by promoting calcium channels dependent release of ACh in STZ-induced diabetic rats
Berberine GERD
1
PM
24137243📋Berberine protects against esophageal mucosal damage in reflux esophagitis by suppressing proinflammatory cytokines
Berberine Helicobacter Pylori Infection
8
PM
37469024📋Efficacy and safety of triple therapy containing berberine, amoxicillin, and vonoprazan for Helicobacter pylori initial treatment: A randomized controlled trial
Berberine Helicobacter Pylori Infection
7
PM
36415112📋Efficacy and safety of triple therapy containing berberine hydrochloride, amoxicillin and rabeprazole in the eradication of Helicobacter pylori
Berberine Helicobacter Pylori Infection
6
PM
33340526📋Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis
Berberine Helicobacter Pylori Infection
1
PM
32116685📋The Efficacy of Berberine-Containing Quadruple Therapy on Helicobacter Pylori Eradication in China: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Berberine Helicobacter Pylori Infection
4
PM
32097666📋Mechanism of Berberine in Treating Helicobacter Pylori Induced Chronic Atrophic Gastritis Through IRF8-IFN-γ Signaling Axis Suppressing
Berberine Helicobacter Pylori Infection
3
PM
29345340📋Berberine Demonstrates Anti-Inflammatory Properties in Helicobacter Pylori-Infected Mice With Chronic Gastritis by Attenuating the Th17 Response Triggered by the B Cell-Activating Factor
Berberine Helicobacter Pylori Infection
2
PM
28796053📋Berberine Containing Quadruple Therapy for Initial Helicobacter Pylori Eradication: An Open-Label Randomized Phase IV Trial
Berberine Helicobacter Pylori Infection
5
PM
25892872📋Inhibitory Effects of Emodin, Baicalin, Schizandrin and Berberine on hefA Gene: Treatment of Helicobacter Pylori-Induced Multidrug Resistance
Berberine Hepatic Encephalopathy
1
PM
37371422📋Effect of Berberine against Cognitive Deficits in Rat Model of Thioacetamide-Induced Liver Cirrhosis and Hepatic Encephalopathy (Behavioral, Biochemical, Molecular and Histological Evaluations)
Berberine Hepatic Fibrosis
5
PM
37062521📋Berberine attenuates liver fibrosis by autophagy inhibition triggering apoptosis via the miR-30a-5p/ATG5 axis
Berberine Hepatic Fibrosis
4
PM
35308208📋Therapeutic Effects of Berberine on Liver Fibrosis are associated With Lipid Metabolism and Intestinal Flora
Berberine Hepatic Fibrosis
2
PM
34864819📋Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis
Berberine Hepatic Fibrosis
1
PM
30138605📋Antioxidant and Anti-Inflammatory Activities of Berberine Attenuate Hepatic Fibrosis Induced by Thioacetamide Injection in Rats
Berberine Hepatic Fibrosis
6
PM
23734997📋Resolution of liver fibrosis by isoquinoline alkaloid berberine in CCl₄-intoxicated mice is mediated by suppression of oxidative stress and upregulation of MMP-2 expression
Berberine Hepatic Fibrosis
7
PM
23190573📋A comparative study on the hepatoprotective action of bear bile and Coptidis Rhizoma aqueous extract on experimental liver fibrosis in rats
Berberine Hepatic Fibrosis
3
PM
19721228📋Berberine Inhibits Hepatic Stellate Cell Proliferation and Prevents Experimental Liver Fibrosis
Berberine Hepatic Ischemia-Reperfusion
1
PM
37780378📋Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2
Berberine Hepatic Steatosis
4
PM
35722423📋Methyltransferase SETD2 mediates hepatoprotection of berberine against steatosis
Berberine Hepatic Steatosis
3
PM
34790723📋Berberine attenuates atherosclerotic lesions and hepatic steatosis in ApoE -/- mice by down-regulating PCSK9 via ERK1/2 pathway
Berberine Hepatic Steatosis
2
PM
29477657📋Berberine Induces miR-373 Expression in Hepatocytes to Inactivate Hepatic Steatosis Associated AKT-S6 Kinase Pathway
Berberine Hepatic Steatosis
1
PM
29065221📋Berberine Attenuates Hepatic Steatosis and Enhances Energy Expenditure in Mice by Inducing Autophagy and Fibroblast Growth Factor 21
Berberine Hepatic Steatosis
5
PM
28900305📋Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells
Berberine Hepatitis C
1
PM
32276448📋Targeting Autophagy Augments BBR-Mediated Cell Death in Human Hepatoma Cells Harboring Hepatitis C Virus RNA
Berberine Inflammatory Bowel Disease
5
PM
35083737📋Berberine and its derivatives represent as the promising therapeutic agents for inflammatory disorders
Berberine Inflammatory Bowel Disease
4
PM
34358871📋Berberine improves intestinal barrier function and reduces inflammation, immunosuppression, and oxidative stress by regulating the NF-κB/MAPK signaling pathway in deoxynivalenol-challenged piglets
Berberine Inflammatory Bowel Disease
2
PM
33285228📋Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites
Berberine Inflammatory Bowel Disease
3
PM
33174609📋Anti‑inflammatory mechanism of berberine on lipopolysaccharide‑induced IEC‑18 models based on comparative transcriptomics
Berberine Inflammatory Bowel Disease
1
PM
27697643📋Berberine and Inflammatory Bowel Disease: A Concise Review
Berberine Inflammatory Bowel Disease
6
PM
22173918📋Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice
Berberine Intestinal Injury
4
PM
38474567📋LC-MS-Based Metabolomics Reveals the Mechanism of Protection of Berberine against Indomethacin-Induced Gastric Injury in Rats
Berberine Intestinal Injury
2
PM
35158228📋Berberine suppresses cecal ligation and puncture induced intestinal injury by enhancing Treg cell function
Berberine Intestinal Injury
1
PM
34174323📋Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways
Berberine Intestinal Injury
3
PM
21963898📋Berberine protects against lipopolysaccharide-induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms
Berberine Intestinal Metaplasia
1
PM
38837097📋Exploring the therapeutic mechanisms of Coptidis Rhizoma in gastric precancerous lesions: a network pharmacology approach
Berberine Intestinal Mucositis
1
PM
34795594📋Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase
Berberine Intestinal Permeability
23
PM
38758516📋Berberine mitigates diclofenac-induced intestinal mucosal mechanical barrier dysfunction through the restoration of autophagy by inhibiting exosome-mediated lncRNA H19
Berberine Intestinal Permeability
22
PM
38108311📋Berberine decreases S100B generation to regulate gut vascular barrier permeability in mice with burn injury
Berberine Intestinal Permeability
15
PM
37046128📋Berberine Enhances Intestinal Mucosal Barrier Function by Promoting Vitamin D Receptor Activity
Berberine Intestinal Permeability
14
PM
36168925📋Berberine alleviates intestinal barrier dysfunction in glucolipid metabolism disorder hamsters by modulating gut microbiota and gut microbiota-related tryptophan metabolites
Berberine Intestinal Permeability
13
PM
35693534📋Anti-Hyperglycemic Agents in the Adjuvant Treatment of Sepsis: Improving Intestinal Barrier Function
Berberine Intestinal Permeability
12
PM
35280677📋Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway
Berberine Intestinal Permeability
11
PM
35259053📋Berberine represses Wnt/β-catenin pathway activation via modulating the microRNA-103a-3p/Bromodomain-containing protein 4 axis, thereby refraining pyroptosis and reducing the intestinal mucosal barrier defect induced via colitis
Berberine Intestinal Permeability
10
PM
34984827📋Berberine ameliorates aGVHD by gut microbiota remodelling, TLR4 signalling suppression and colonic barrier repairment for NLRP3 inflammasome inhibition
Berberine Intestinal Permeability
9
PM
34358871📋Berberine improves intestinal barrier function and reduces inflammation, immunosuppression, and oxidative stress by regulating the NF-κB/MAPK signaling pathway in deoxynivalenol-challenged piglets
Berberine Intestinal Permeability
8
PM
34253428📋Dihydroberberine, an isoquinoline alkaloid, exhibits protective effect against dextran sulfate sodium-induced ulcerative colitis in mice
Berberine Intestinal Permeability
7
PM
34025574📋Berberine Slows the Progression of Prediabetes to Diabetes in Zucker Diabetic Fatty Rats by Enhancing Intestinal Secretion of Glucagon-Like Peptide-2 and Improving the Gut Microbiota
Berberine Intestinal Permeability
6
PM
33285228📋Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites
Berberine Intestinal Permeability
5
PM
32961234📋Berberine reduces gut-vascular barrier permeability via modulation of ApoM/S1P pathway in a model of polymicrobial sepsis
Berberine Intestinal Permeability
4
PM
32750460📋Berberine inhibits intestinal epithelial barrier dysfunction in colon caused by peritoneal dialysis fluid by improving cell migration
Berberine Intestinal Permeability
3
PM
32403887📋[Discussion on the Curative Effect and Mechanisms of Berberine in Rats With Non-Alcoholic Fatty Liver]
Berberine Intestinal Permeability
2
PM
32360278📋Berberine Improved Intestinal Barrier Function by Modulating the Intestinal Microbiota in Blunt Snout Bream (Megalobrama Amblycephala) Under Dietary High-Fat and High-Carbohydrate Stress
Berberine Intestinal Permeability
20
PM
29202334📋Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe-/- mice
Berberine Intestinal Permeability
19
PM
29200733📋Amelioration of Intestinal Barrier Dysfunction by Berberine in the Treatment of Nonalcoholic Fatty Liver Disease in Rats
Berberine Intestinal Permeability
18
PM
29154866📋Activation of IGF-1/IGFBP-3 signaling by berberine improves intestinal mucosal barrier of rats with acute endotoxemia
Berberine Intestinal Permeability
17
PM
23757509📋Alteration of the intestinal barrier and GLP2 secretion in Berberine-treated type 2 diabetic rats
Berberine Intestinal Permeability
16
PM
23671580📋Amelioration of IFN-γ and TNF-α-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathway
Berberine Intestinal Permeability
21
PM
21592990📋Berberine ameliorates intestinal epithelial tight-junction damage and down-regulates myosin light chain kinase pathways in a mouse model of endotoxinemia
Berberine Intestinal Permeability
1
PM
20149867📋Berberine Attenuates Pro-Inflammatory Cytokine-Induced Tight Junction Disruption in an in Vitro Model of Intestinal Epithelial Cells
Berberine Irritable Bowel Syndrome
8
PM
38674895📋The Possible Synergistic Pharmacological Effect of an Oral Berberine (BBR) and Curcumin (CUR) Complementary Therapy Alleviates Symptoms of Irritable Bowel Syndrome (IBS): Results from a Real-Life, Routine Clinical Practice Settings-Based Study
Berberine Irritable Bowel Syndrome
6
PM
34594213📋Therapeutic Effects of Berberine Hydrochloride on Stress-Induced Diarrhea-Predominant Irritable Bowel Syndrome Rats by Inhibiting Neurotransmission in Colonic Smooth Muscle
Berberine Irritable Bowel Syndrome
5
PM
33558654📋Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation
Berberine Irritable Bowel Syndrome
4
PM
32283882📋Role of a Berberine-Based Nutritional Supplement in Reducing Diarrhea in Subjects With Functional Gastrointestinal Disorders
Berberine Irritable Bowel Syndrome
2
PM
31413530📋Berberine Prevents Stress-Induced Gut Inflammation and Visceral Hypersensitivity and Reduces Intestinal Motility in Rats
Berberine Irritable Bowel Syndrome
3
PM
29891588📋Berberine Upregulates P-Glycoprotein in Human Caco-2 Cells and in an Experimental Model of Colitis in the Rat via Activation of Nrf2-Dependent Mechanisms
Berberine Irritable Bowel Syndrome
1
PM
26700862📋Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner
Berberine Irritable Bowel Syndrome
7
PM
23600391📋Effects of berberine on rat jejunal motility
Berberine Liver Cancer
34
PM
38750718📋Berberine increases the killing effect of pirarubicin on HCC cells by inhibiting ATG4B-autophagy pathway
Berberine Liver Cancer
33
PM
38693042📋The potential of the nutraceutical berberine in the treatment of hepatocellular carcinoma and other liver diseases such as NAFLD and NASH
Berberine Liver Cancer
32
PM
38301771📋Berberine prevents NAFLD and HCC by modulating metabolic disorders
Berberine Liver Cancer
31
PM
38084140📋Inhibition of hepatocellular carcinoma growth via modulation of the miR-221/SOX11 axis by curcumin and berberine
Berberine Liver Cancer
25
PM
37148713📋Berberine activates PPARδ and promotes gut microbiota-derived butyric acid to suppress hepatocellular carcinoma
Berberine Liver Cancer
24
PM
36191360📋Hepatocellular cancer cell lines, Hep-3B and Hep-G2 display the pleiotropic response to resveratrol and berberine
Berberine Liver Cancer
23
PM
36090480📋Berberine inhibits carcinogenesis through antagonizing the ATX-LPA-LPAR2-p38-leptin axis in a mouse hepatoma model
Berberine Liver Cancer
22
PM
34787617📋Antiproliferative activity of berberine in HepG2 cells via inducing apoptosis and arresting cell cycle
Berberine Liver Cancer
21
PM
34712379📋Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGF β R Regulating TGF- β/Smad Pathway
Berberine Liver Cancer
20
PM
34460138📋A novel combined resveratrol/berberine phytochemotheraputic using the HePG2 cell line as a model for the treatment of hepatocarcinoma
Berberine Liver Cancer
19
PM
34395446📋Probing Synergistic Targets by Natural Compounds for Hepatocellular Carcinoma
Berberine Liver Cancer
18
PM
34220494📋Berberine Sensitizes Human Hepatoma Cells to Regorafenib via Modulating Expression of Circular RNAs
Berberine Liver Cancer
17
PM
33130557📋Berberine represses β-catenin translation involving 4E-BPs in hepatocellular carcinoma cells
Berberine Liver Cancer
29
PM
32815562📋Berberine, a natural alkaloid sensitizes human hepatocarcinoma to ionizing radiation by blocking autophagy and cell cycle arrest resulting in senescence
Berberine Liver Cancer
16
PM
32606742📋Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma
Berberine Liver Cancer
15
PM
32276448📋Targeting Autophagy Augments BBR-Mediated Cell Death in Human Hepatoma Cells Harboring Hepatitis C Virus RNA
Berberine Liver Cancer
2
PM
32021249📋Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake
Berberine Liver Cancer
11
PM
31545468📋Exploring the Active Mechanism of Berberine Against HCC by Systematic Pharmacology and Experimental Validation
Berberine Liver Cancer
4
PM
31217846📋Berberine Prevents Non-Alcoholic Steatohepatitis-Derived Hepatocellular Carcinoma by Inhibiting Inflammation and Angiogenesis in Mice
Berberine Liver Cancer
3
PM
30565332📋Synergistic Effect of Berberine and HMQ1611 Impairs Cell Proliferation and Migration by Regulating Wnt Signaling Pathway in Hepatocellular Carcinoma
Berberine Liver Cancer
10
PM
30015938📋Berberine, a Natural Plant Alkaloid, Synergistically Sensitizes Human Liver Cancer Cells to Sorafenib
Berberine Liver Cancer
6
PM
29626488📋Berberine Induced Modulation of PHLPP2-Akt-MST1 Kinase Signaling Is Coupled With Mitochondrial Impairment and Hepatoma Cell Death
Berberine Liver Cancer
5
PM
29360760📋Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells
Berberine Liver Cancer
7
PM
28572744📋Berberine Regulates the Protein Expression of Multiple Tumorigenesis-Related Genes in Hepatocellular Carcinoma Cell Lines
Berberine Liver Cancer
8
PM
28277195📋Induction of Apoptosis by Berberine in Hepatocellular Carcinoma HepG2 Cells via Downregulation of NF-κB
Berberine Liver Cancer
14
PM
27854312📋Berberine Suppresses Cyclin D1 Expression Through Proteasomal Degradation in Human Hepatoma Cells
Berberine Liver Cancer
9
PM
27311637📋Antiproliferation of Berberine Is Mediated by Epigenetic Modification of Constitutive Androstane Receptor (CAR) Metabolic Pathway in Hepatoma Cells
Berberine Liver Cancer
13
PM
27092498📋Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine
Berberine Liver Cancer
28
PM
23999088📋Berberine and S allyl cysteine mediated amelioration of DEN+CCl4 induced hepatocarcinoma
Berberine Liver Cancer
27
PM
23784371📋Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells
Berberine Liver Cancer
26
PM
23732865📋Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma
Berberine Liver Cancer
30
PM
21443647📋Berberine induces cell death in human hepatoma cells in vitro by downregulating CD147
Berberine Liver Cancer
12
PM
19724899📋Coptis Chinensis Inhibits Hepatocellular Carcinoma Cell Growth Through Nonsteroidal Anti-Inflammatory Drug-Activated Gene Activation
Berberine Liver Cancer
1
PM
19408145📋Berbamine Induces Fas-mediated Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells and Inhibits Its Tumor Growth in Nude Mice
Berberine Liver Damage
1
PM
35436630📋Hydrochloride Berberine ameliorates alcohol-induced liver injury by regulating inflammation and lipid metabolism
Berberine Liver Damage
6
PM
35078575📋[Berberine hydrochloride attenuates liver injury induced by acute hypoxic exposure by inhibiting TNF-α/caspase-8/caspase-3 signaling pathway]
Berberine Liver Disease
4
PM
38693042📋The potential of the nutraceutical berberine in the treatment of hepatocellular carcinoma and other liver diseases such as NAFLD and NASH
Berberine Liver Disease
3
PM
34056769📋Molecular updates on berberine in liver diseases: Bench to bedside
Berberine Liver Disease
2
PM
33068590📋The pharmacological activity of berberine, a review for liver protection
Berberine Liver Disease
1
PM
32265720📋The Impacts of Herbal Medicines and Natural Products on Regulating the Hepatic Lipid Metabolism
Berberine MAFLD
35
PM
38762210📋Berberine directly targets AKR1B10 protein to modulate lipid and glucose metabolism disorders in NAFLD
Berberine MAFLD
34
PM
38723878📋Berberine ameliorates nonalcoholic fatty liver disease-induced bone loss by inhibiting ferroptosis
Berberine MAFLD
33
PM
38673787📋Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Berberine MAFLD
32
PM
38429794📋The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Berberine MAFLD
31
PM
38301771📋Berberine prevents NAFLD and HCC by modulating metabolic disorders
Berberine MAFLD
28
PM
37293270📋Berberine alleviates non-alcoholic hepatic steatosis partially by promoting SIRT1 deacetylation of CPT1A in mice
Berberine MAFLD
27
PM
36838862📋Berberine Ameliorates Metabolic-Associated Fatty Liver Disease Mediated Metabolism Disorder and Redox Homeostasis by Upregulating Clock Genes: Clock and Bmal1 Expressions
Berberine MAFLD
26
PM
36079717📋Berberine in Non-Alcoholic Fatty Liver Disease-A Review
Berberine MAFLD
25
PM
35873595📋Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota
Berberine MAFLD
24
PM
35726797📋Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD rats
Berberine MAFLD
23
PM
35722423📋Methyltransferase SETD2 mediates hepatoprotection of berberine against steatosis
Berberine MAFLD
22
PM
35584453📋The combination of berberine and evodiamine ameliorates high-fat diet-induced non-alcoholic fatty liver disease associated with modulation of gut microbiota in rats
Berberine MAFLD
21
PM
35382695📋Effect of berberine and bicyclol on Chinese patients with non-alcoholic fatty liver disease: a retrospective study
Berberine MAFLD
20
PM
35359076📋[Berberine alleviates programmed necrosis of metabolic-associated fatty liver disease via activating Nrf2 pathway in mice]
Berberine MAFLD
19
PM
35250593📋Combined Use of Bicyclol and Berberine Alleviates Mouse Nonalcoholic Fatty Liver Disease
Berberine MAFLD
18
PM
34566663📋Preclinical Evidence of Berberine on Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Animal Studies
Berberine MAFLD
17
PM
34504563📋Berberine ameliorates nonalcoholic fatty liver disease by decreasing the liver lipid content via reversing the abnormal expression of MTTP and LDLR
Berberine MAFLD
16
PM
34094026📋The therapeutic effects of berberine plus sitagliptin in a rat model of fatty liver disease
Berberine MAFLD
15
PM
33831691📋Therapeutic effect of oxyberberine on obese non-alcoholic fatty liver disease rats
Berberine MAFLD
14
PM
33626003📋Berberine inhibits liver damage in rats with non-alcoholic fatty liver disease by regulating TLR4/MyD88/NF-κB pathway
Berberine MAFLD
13
PM
32429849📋Anti-inflammatory Activity of Berberine in Non-Alcoholic Fatty Liver Disease via the Angptl2 Pathway
Berberine MAFLD
12
PM
32403887📋[Discussion on the Curative Effect and Mechanisms of Berberine in Rats With Non-Alcoholic Fatty Liver]
Berberine MAFLD
11
PM
32357187📋Berberine Inhibits Free Fatty Acid and LPS-induced Inflammation via Modulating ER Stress Response in Macrophages and Hepatocytes
Berberine MAFLD
1
PM
32194416📋Berberine Inhibits Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation and Pyroptosis in Nonalcoholic Steatohepatitis via the ROS/TXNIP Axis
Berberine MAFLD
7
PM
31226399📋Berberine Attenuates Nonalcoholic Hepatic Steatosis Through the AMPK-SREBP-1c-SCD1 Pathway
Berberine MAFLD
4
PM
30868489📋Berberine Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats via Activation of SIRT3/AMPK/ACC Pathway
Berberine MAFLD
6
PM
30867696📋Berberine Attenuates Hepatic Oxidative Stress in Rats With Non-Alcoholic Fatty Liver Disease via the Nrf2/ARE Signalling Pathway
Berberine MAFLD
3
PM
30848932📋Berberine Alleviates Nonalcoholic Fatty Liver Induced by a High-Fat Diet in Mice by Activating SIRT3
Berberine MAFLD
2
PM
29505790📋Berberine Alleviates Hepatic Lipid Accumulation by Increasing ABCA1 Through the Protein Kinase C δ Pathway
Berberine MAFLD
10
PM
29353208📋Natural Products Berberine and Curcumin Exhibited Better Ameliorative Effects on Rats With Non-Alcohol Fatty Liver Disease Than Lovastatin
Berberine MAFLD
29
PM
29200733📋Amelioration of Intestinal Barrier Dysfunction by Berberine in the Treatment of Nonalcoholic Fatty Liver Disease in Rats
Berberine MAFLD
8
PM
26936230📋Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice With Diet-induced Obesity
Berberine MAFLD
9
PM
26857750📋Berberine Prevents Progression From Hepatic Steatosis to Steatohepatitis and Fibrosis by Reducing Endoplasmic Reticulum Stress
Berberine MAFLD
5
PM
26252777📋Efficacy of Berberine in Patients With Non-Alcoholic Fatty Liver Disease
Berberine MAFLD
30
PM
21839075📋Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver
Berberine Nasopharyngeal Cancer
7
PM
38213727📋Berberine-mediated Ferroptosis through System Xc-/GSH/GPX4 Axis Inhibits Metastasis of Nasopharyngeal Carcinoma
Berberine Nasopharyngeal Cancer
3
PM
28350122📋Berberine Sensitizes Nasopharyngeal Carcinoma Cells to Radiation Through Inhibition of Sp1 and EMT
Berberine Nasopharyngeal Cancer
1
PM
28259949📋Berberine Inhibits the Proliferation of Human Nasopharyngeal Carcinoma Cells via an Epstein-Barr Virus Nuclear Antigen 1-dependent Mechanism
Berberine Nasopharyngeal Cancer
6
PM
24641420📋Berberine hydrochloride impact on physiological processes and modulation of twist levels in nasopharyngeal carcinoma CNE-1 cells
Berberine Nasopharyngeal Cancer
5
PM
24380387📋Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts
Berberine Nasopharyngeal Cancer
4
PM
24325635📋Berberine radiosensitizes human nasopharyngeal carcinoma by suppressing hypoxia-inducible factor-1α expression
Berberine Nasopharyngeal Cancer
2
PM
19513545📋Berberine Inhibits Rho GTPases and Cell Migration at Low Doses but Induces G2 Arrest and Apoptosis at High Doses in Human Cancer Cells
Berberine Necrotizing Enterocolitis
1
PM
30542485📋Berberine Reduces the Occurrence of Neonatal Necrotizing Enterocolitis by Reducing the Inflammatory Response
Berberine Non-Alcoholic Steatohepatitis
10
PM
37652508📋Comparing the Influences of Metformin and Berberine on the Intestinal Microbiota of Rats With Nonalcoholic Steatohepatitis
Berberine Non-Alcoholic Steatohepatitis
9
PM
34686466📋Berberine mitigates nonalcoholic hepatic steatosis by downregulating SIRT1-FoxO1-SREBP2 pathway for cholesterol synthesis
Berberine Non-Alcoholic Steatohepatitis
8
PM
34603061📋Berberine Alleviates Non-alcoholic Steatohepatitis Through Modulating Gut Microbiota Mediated Intestinal FXR Activation
Berberine Non-Alcoholic Steatohepatitis
7
PM
34566663📋Preclinical Evidence of Berberine on Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Animal Studies
Berberine Non-Alcoholic Steatohepatitis
6
PM
33494295📋Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways
Berberine Non-Alcoholic Steatohepatitis
5
PM
32524150📋Berberine Attenuates Non-Alcoholic Steatohepatitis by Regulating chemerin/CMKLR1 Signalling Pathway and Treg/Th17 Ratio
Berberine Non-Alcoholic Steatohepatitis
2
PM
32194416📋Berberine Inhibits Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation and Pyroptosis in Nonalcoholic Steatohepatitis via the ROS/TXNIP Axis
Berberine Non-Alcoholic Steatohepatitis
4
PM
31217846📋Berberine Prevents Non-Alcoholic Steatohepatitis-Derived Hepatocellular Carcinoma by Inhibiting Inflammation and Angiogenesis in Mice
Berberine Non-Alcoholic Steatohepatitis
3
PM
29075339📋Berberine Ameliorates Non-Alcoholic Steatohepatitis in ApoE -/- Mice
Berberine Non-Alcoholic Steatohepatitis
1
PM
26923892📋Modulation of Gut Microbiota by Berberine Improves Steatohepatitis in High-Fat Diet-Fed BALB/C Mice
Berberine Oral Cancer
1
PM
29113353📋Berberine-targeted miR-21 Chemosensitizes Oral Carcinomas Stem Cells
Berberine Oral Candidiasis
1
PM
38729536📋Coptidis rhizoma extract alleviates oropharyngeal candidiasis by gC1qR-EGFR/ERK/c-fos axis-induced endocytosis of oral epithelial cells
Berberine Pancreatic Cancer
8
PM
38502348📋Berberine chloride suppresses pancreatic adenocarcinoma proliferation and growth by targeting inflammation-related genes: an in silico analysis with in vitro and vivo validation
Berberine Pancreatic Cancer
7
PM
36500723📋Effects of Berberine against Pancreatitis and Pancreatic Cancer
Berberine Pancreatic Cancer
6
PM
36297310📋Berberine Overcomes Gemcitabine-Associated Chemoresistance through Regulation of Rap1/PI3K-Akt Signaling in Pancreatic Ductal Adenocarcinoma
Berberine Pancreatic Cancer
5
PM
35784732📋Berberine Suppresses Lung Metastasis of Cancer via Inhibiting Endothelial Transforming Growth Factor Beta Receptor 1
Berberine Pancreatic Cancer
4
PM
34890544📋Berberine inhibits pancreatic intraepithelial neoplasia by inhibiting glycolysis via the adenosine monophosphate -activated protein kinase pathway
Berberine Pancreatic Cancer
3
PM
34185423📋Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression
Berberine Pancreatic Cancer
2
PM
32692565📋Cell metabolomics reveal berberine inhibited pancreatic cancer cell viability and metastasis by regulating citrate metabolism
Berberine Pancreatic Cancer
1
PM
20455200📋Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells
Berberine Pancreatic Fibrosis
1
PM
32721432📋Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smad signaling and M2 polarization
Berberine Pancreatitis
2
PM
36500723📋Effects of Berberine against Pancreatitis and Pancreatic Cancer
Berberine Pancreatitis
1
PM
34890544📋Berberine inhibits pancreatic intraepithelial neoplasia by inhibiting glycolysis via the adenosine monophosphate -activated protein kinase pathway
Berberine Pancreatitis
4
PM
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