| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Aloin | Colon Cancer | 2 | PM | 23928829 | 📋 | Chemopreventive effects of aloin against 1,2-dimethylhydrazine-induced preneoplastic lesions in the colon of Wistar rats |
| Aloin | Colon Cancer | 1 | PM | 19941474 | 📋 | Antitumor Properties and Modulation of Antioxidant Enzymes' Activity by Aloe Vera Leaf Active Principles Isolated via Supercritical Carbon Dioxide Extraction |
| Aloin | Colorectal Cancer | 1 | PM | 38000359 | 📋 | Aloin and CPT-11 combination activates miRNA-133b and downregulates IGF1R- PI3K/AKT/mTOR and MEK/ERK pathways to inhibit colorectal cancer progression |
| Aloin | Gastric Cancer | 3 | PM | 37313810 | 📋 | [Aloin inhibits gastric cancer cell proliferation and migration by suppressing the STAT3/HMGB1 signaling pathway] |
| Aloin | Gastric Cancer | 2 | PM | 35757520 | 📋 | Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer |
| Aloin | Gastric Cancer | 1 | PM | 34916197 | 📋 | [Aloin inhibits lactate-induced proliferation and migration of gastric cancer cells by downregulating HMGB1 expression] |
| Aloin | Gastric Cancer | 6 | PM | 32021099 | 📋 | Aloin Inhibits the Proliferation and Migration of Gastric Cancer Cells by Regulating NOX2-ROS-Mediated Pro-Survival Signal Pathways |
| Aloin | Gastric Cancer | 5 | PM | 31114162 | 📋 | The molecular mechanisms of Aloin induce gastric cancer cells apoptosis by targeting High Mobility Group Box 1 |
| Aloin | Gastric Cancer | 4 | PM | 30377097 | 📋 | [Aloin induces apoptosis via regulating the activation of MAPKs signaling pathway in human gastric cancer cells in vitro] |
| Aloin | Hepatic Fibrosis | 1 | PM | 38038700 | 📋 | Aloin Attenuates Oxidative Stress, Inflammation, and CCl4-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling |
| Aloin | Hepatic Ischemia-Reperfusion | 1 | PM | 31827674 | 📋 | Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF- κ B Signal Pathway In Vivo and In Vitro |
| Aloin | Intestinal Permeability | 1 | PM | 36075180 | 📋 | Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway |
| Aloin | Liver Cancer | 1 | PM | 34720052 | 📋 | Aloin decelerates the progression of hepatocellular carcinoma through circ_0011385/miR-149-5p/WT1 axis |
| Aloin | Liver Cancer | 2 | PM | 31830378 | 📋 | Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway |
| Aloin | Non-Alcoholic Steatohepatitis | 1 | PM | 33410857 | 📋 | Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling |
| Aloin | Ulcerative Colitis | 2 | PM | 36075180 | 📋 | Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway |
| Aloin | Ulcerative Colitis | 1 | PM | 33839199 | 📋 | Aloe vera mitigates dextran sulfate sodium-induced rat ulcerative colitis by potentiating colon mucus barrier |
| Aloin | Ulcerative Colitis | 3 | PM | 21277867 | 📋 | Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model |
