Substance | Condition | Seq | Src | PMID | Dtl | Title |
Quercetin | Diabetes | 13 | PM | 38027372 | 📋 | In Silico and In Vitro Analyses to Repurpose Quercetin as a Human Pancreatic α-Amylase Inhibitor |
Quercetin | Diabetes | 10 | PM | 36496468 | 📋 | Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide- induced diabetic rats |
Quercetin | Diabetes | 9 | PM | 35892731 | 📋 | Quercetin: A Molecule of Great Biochemical and Clinical Value and Its Beneficial Effect on Diabetes and Cancer |
Quercetin | Diabetes | 8 | PM | 35468007 | 📋 | Quercetin: an effective polyphenol in alleviating diabetes and diabetic complications |
Quercetin | Diabetes | 7 | PM | 34620011 | 📋 | The roles of quercetin in diabetes mellitus and related metabolic disorders; special focus on the modulation of gut microbiota: A comprehensive review |
Quercetin | Diabetes | 6 | PM | 34161695 | 📋 | Behavioral and biochemical investigations to explore the efficacy of quercetin and folacin in experimental diabetes induced vascular endothelium dysfunction and associated dementia in rats |
Quercetin | Diabetes | 5 | PM | 34051305 | 📋 | The synergistic protection of EGCG and quercetin against streptozotocin (STZ)-induced NIT-1 pancreatic β cell damage via upregulation of BCL-2 expression by miR-16-5p |
Quercetin | Diabetes | 11 | PM | 29169872 | 📋 | Quercetin improves endothelial function in diabetic rats through inhibition of endoplasmic reticulum stress-mediated oxidative stress |
Quercetin | Diabetes | 12 | PM | 28395272 | 📋 | The effect of hesperidin and quercetin on oxidative stress, NF-κB and SIRT1 levels in a STZ-induced experimental diabetes model |
Quercetin | Diabetes | 1 | PM | 27975068 | 📋 | Quercetin Isolated From Toona sinensis Leaves Attenuates Hyperglycemia and Protects Hepatocytes in High-Carbohydrate/High-Fat Diet and Alloxan Induced Experimental Diabetic Mice |
Quercetin | Diabetes | 2 | PM | 26393568 | 📋 | Selected Phytochemicals and Culinary Plant Extracts Inhibit Fructose Uptake in Caco-2 Cells |
Quercetin | Diabetes | 4 | PM | 26286521 | 📋 | Melatonin, Quercetin and Resveratrol Attenuates Oxidative Hepatocellular Injury in Streptozotocin-Induced Diabetic Rats |
Quercetin | Diabetes | 3 | PM | 21277296 | 📋 | DNA-protective Effects of Quercetin or Naringenin in Alloxan-Induced Diabetic Mice |
Quercetin | Diabetes Type 1 | 2 | PM | 35594707 | 📋 | Quercetin ameliorates oxidative stress‑induced cell apoptosis of seminal vesicles via activating Nrf2 in type 1 diabetic rats |
Quercetin | Diabetes Type 1 | 1 | PM | 34855213 | 📋 | Antidiabetic effects of quercetin and liraglutide combination through modulation of TXNIP/IRS-1/PI3K pathway |
Quercetin | Diabetes Type 2 | 17 | PM | 38745810 | 📋 | The Impact of Three-Month Quercetin Intake on Quality of Life and Anxiety in Patients With Type II Diabetes Mellitus: An Early Data Analysis From a Randomized Controlled Trial |
Quercetin | Diabetes Type 2 | 16 | PM | 38332532 | 📋 | Identification of the shared genes in type 2 diabetes mellitus and osteoarthritis and the role of quercetin |
Quercetin | Diabetes Type 2 | 15 | PM | 37453091 | 📋 | Anti-diabetic effect of quercetin in type 2 diabetes mellitus by regulating the microRNA-92b-3p/EGR1 axis |
Quercetin | Diabetes Type 2 | 14 | PM | 35643286 | 📋 | Quercetin protects against palmitate-induced pancreatic β-cell apoptosis by restoring lysosomal function and autophagic flux |
Quercetin | Diabetes Type 2 | 13 | PM | 35344738 | 📋 | Antidiabetic efficacy of Trifolium alexandrinum extracts hesperetin and quercetin in ameliorating carbohydrate metabolism and activating IR and AMPK signaling in the pancreatic tissues of diabetic rats |
Quercetin | Diabetes Type 2 | 12 | PM | 34953390 | 📋 | Quercetin for managing type 2 diabetes and its complications, an insight into multitarget therapy |
Quercetin | Diabetes Type 2 | 7 | PM | 34824300 | 📋 | Mechanism of quercetin therapeutic targets for Alzheimer disease and type 2 diabetes mellitus |
Quercetin | Diabetes Type 2 | 6 | PM | 34443451 | 📋 | Beneficial Effect of Quercetin on Erythrocyte Properties in Type 2 Diabetic Rats |
Quercetin | Diabetes Type 2 | 4 | PM | 34249264 | 📋 | Quercetin protects islet β-cells from oxidation-induced apoptosis via Sirt3 in T2DM |
Quercetin | Diabetes Type 2 | 1 | PM | 34129156 | 📋 | Quercetin improves oxidative stress-induced pancreatic beta cell alterations via mTOR-signaling |
Quercetin | Diabetes Type 2 | 11 | PM | 33021114 | 📋 | Protective effects of quercetin and crocin in the kidneys and liver of obese Sprague-Dawley rats with Type 2 diabetes: Effects of quercetin and crocin on T2DM rats |
Quercetin | Diabetes Type 2 | 10 | PM | 32992479 | 📋 | Quercetin Alleviates Ferroptosis of Pancreatic β Cells in Type 2 Diabetes |
Quercetin | Diabetes Type 2 | 9 | PM | 32795923 | 📋 | Swertiamarin and quercetin combination ameliorates hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced type 2 diabetes mellitus in wistar rats |
Quercetin | Diabetes Type 2 | 8 | PM | 31876980 | 📋 | Quercetin Modulates Hyperglycemia by Improving the Pancreatic Antioxidant Status and Enzymes Activities Linked With Glucose Metabolism in Type 2 Diabetes Model of Rats: In Silico Studies of Molecular Interaction of Quercetin With Hexokinase and Catalase |
Quercetin | Diabetes Type 2 | 5 | PM | 29736297 | 📋 | Anti-diabetic Activity of Quercetin Extracted From Phyllanthus emblica L. Fruit: In silico and in vivo Approaches |
Quercetin | Diabetes Type 2 | 2 | PM | 28783583 | 📋 | Influence of Quercetin, Naringenin and Berberine on Glucose Transporters and Insulin Signalling Molecules in Brain of Streptozotocin-Induced Diabetic Rats |
Quercetin | Diabetes Type 2 | 3 | PM | 27343476 | 📋 | Influence of Piperine and Quercetin on Antidiabetic Potential of Curcumin |
Quercetin | Diabetic Cardiomyopathy | 9 | PM | 38716618 | 📋 | Quercetin Ameliorates Myocardial Injury in Diabetic Rats by Regulating Autophagy and Apoptosis through AMPK/mTOR Signaling Pathway |
Quercetin | Diabetic Cardiomyopathy | 8 | PM | 36624860 | 📋 | Quercetin Inhibits Pyroptosis in Diabetic Cardiomyopathy through the Nrf2 Pathway |
Quercetin | Diabetic Cardiomyopathy | 7 | PM | 36568083 | 📋 | Quercetin alleviates diastolic dysfunction and suppresses adverse pro-hypertrophic signaling in diabetic rats |
Quercetin | Diabetic Cardiomyopathy | 6 | PM | 35770736 | 📋 | Quercetin ameliorated cardiac injury via reducing inflammatory actions and the glycerophospholipid metabolism dysregulation in a diabetic cardiomyopathy mouse model |
Quercetin | Diabetic Cardiomyopathy | 5 | PM | 35643067 | 📋 | Combined use of systemic quercetin, glutamine and alpha-tocopherol attenuates myocardial fibrosis in diabetic rats |
Quercetin | Diabetic Cardiomyopathy | 4 | PM | 35108360 | 📋 | Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age |
Quercetin | Diabetic Cardiomyopathy | 3 | PM | 35048283 | 📋 | Quercetin and vitamin E ameliorate cardio-apoptotic risks in diabetic rats |
Quercetin | Diabetic Cardiomyopathy | 2 | PM | 34523301 | 📋 | Quercetin improves myocardial redox status in rats with type 2 diabetes |
Quercetin | Diabetic Cardiomyopathy | 1 | PM | 33906539 | 📋 | Cardioprotective potential of melatonin, quercetin and resveratrol in an experimental model of diabetes |
Quercetin | Diabetic Cataract | 2 | PM | 32900356 | 📋 | Quercetin inhibits AQP1 translocation in high-glucose-cultured SRA01/04 cells through PI3K/Akt/mTOR Pathway |
Quercetin | Diabetic Cataract | 3 | PM | 30729071 | 📋 | Dietary flavonoids inhibit the glycation of lens proteins: implications in the management of diabetic cataract |
Quercetin | Diabetic Cataract | 1 | PM | 29281744 | 📋 | Antidiabetic Cataract Effects of GbE, Rutin and Quercetin Are Mediated by the Inhibition of Oxidative Stress and Polyol Pathway |
Quercetin | Diabetic Complications | 16 | PM | 36677055 | 📋 | Quercetin, a Plant Flavonol Attenuates Diabetic Complications, Renal Tissue Damage, Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats |
Quercetin | Diabetic Complications | 15 | PM | 36648717 | 📋 | Protective effect of quercetin on pulmonary dysfunction in streptozotocin-induced diabetic rats via inhibition of NLRP3 signaling pathway |
Quercetin | Diabetic Complications | 14 | PM | 35689230 | 📋 | Quercetin treatment protects the Achilles tendons of rats from oxidative stress induced by hyperglycemia |
Quercetin | Diabetic Complications | 13 | PM | 35468007 | 📋 | Quercetin: an effective polyphenol in alleviating diabetes and diabetic complications |
Quercetin | Diabetic Complications | 12 | PM | 34582743 | 📋 | Quercetin ameliorates testosterone secretion disorder by inhibiting endoplasmic reticulum stress through the miR-1306-5p/HSD17B7 axis in diabetic rats |
Quercetin | Diabetic Complications | 11 | PM | 34275146 | 📋 | Quercetin and vitamin E attenuate diabetes-induced testicular anomaly in Wistar rats via the mitochondrial-mediated apoptotic pathway |
Quercetin | Diabetic Complications | 10 | PM | 34061009 | 📋 | Effects of Quercetin and Coenzyme Q10 on Biochemical, Molecular, and Morphological Parameters of Skeletal Muscle in Trained Diabetic Rats |
Quercetin | Diabetic Complications | 9 | PM | 33640557 | 📋 | Protective effect of quercetin on alteration of antioxidant genes expression and histological changes in the dental pulp of the streptozotocin-diabetic rats |
Quercetin | Diabetic Complications | 7 | PM | 33218414 | 📋 | Protective effects of quercetin on uterine receptivity markers and blastocyst implantation rate in diabetic pregnant mice |
Quercetin | Diabetic Complications | 1 | PM | 31889455 | 📋 | Ameliorative Effects of Quercetin on Folliculogenesis in Diabetic Mice: A Stereological Study |
Quercetin | Diabetic Complications | 5 | PM | 31606511 | 📋 | Quercetin Promotes Diabetic Wound Healing via Switching Macrophages From M1 to M2 Polarization |
Quercetin | Diabetic Complications | 2 | PM | 29477473 | 📋 | Quercetin and Low Level Laser Therapy Promote Wound Healing Process in Diabetic Rats via Structural Reorganization and Modulatory Effects on Inflammation and Oxidative Stress |
Quercetin | Diabetic Complications | 4 | PM | 28027533 | 📋 | Quercetin Ameliorates Oxidative Stress, Inflammation and Apoptosis in the Heart of Streptozotocin-Nicotinamide-Induced Adult Male Diabetic Rats |
Quercetin | Diabetic Complications | 3 | PM | 24953551 | 📋 | Synergistic Effect of Quercetin and Quinic Acid by Alleviating Structural Degeneration in the Liver, Kidney and Pancreas Tissues of STZ-induced Diabetic Rats: A Mechanistic Study |
Quercetin | Diabetic Encephalopathy | 4 | PM | 38377720 | 📋 | Quercetin: A promising therapy for diabetic encephalopathy through inhibition of hippocampal ferroptosis |
Quercetin | Diabetic Encephalopathy | 3 | PM | 38253310 | 📋 | Quercetin modulates expression of serum exosomal long noncoding RNA NEAT1 to regulate the miR-129-5p/BDNF axis and attenuate cognitive impairment in diabetic mice |
Quercetin | Diabetic Encephalopathy | 2 | PM | 36118693 | 📋 | Quercetin targets VCAM1 to prevent diabetic cerebrovascular endothelial cell injury |
Quercetin | Diabetic Encephalopathy | 1 | PM | 32000299 | 📋 | Quercetin Protects Against Diabetic Encephalopathy via SIRT1/NLRP3 Pathway in Db/Db Mice |
Quercetin | Diabetic Nephropathy | 18 | PM | 38796641 | 📋 | Quercetin prevents kidney against diabetes mellitus (type 1) in rats by inhibiting TGF-β/apelin gene expression |
Quercetin | Diabetic Nephropathy | 17 | PM | 38761776 | 📋 | Senolytic combination of dasatinib and quercetin attenuates renal damage in diabetic kidney disease |
Quercetin | Diabetic Nephropathy | 16 | PM | 38725104 | 📋 | Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway |
Quercetin | Diabetic Nephropathy | 15 | PM | 38574626 | 📋 | Biomedicine and pharmacotherapeutic effectiveness of combinatorial atorvastatin and quercetin on diabetic nephropathy: An in vitro study |
Quercetin | Diabetic Nephropathy | 14 | PM | 38465879 | 📋 | Quercetin improves diabetic kidney disease by inhibiting ferroptosis and regulating the Nrf2 in streptozotocin-induced diabetic rats |
Quercetin | Diabetic Nephropathy | 13 | PM | 38240118 | 📋 | Senolytic combination of dasatinib and quercetin protects against diabetic kidney disease by activating autophagy to alleviate podocyte dedifferentiation via the Notch pathway |
Quercetin | Diabetic Nephropathy | 12 | PM | 37046368 | 📋 | Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway |
Quercetin | Diabetic Nephropathy | 11 | PM | 35908521 | 📋 | Effective dose/duration of natural flavonoid quercetin for treatment of diabetic nephropathy: A systematic review and meta-analysis of rodent data |
Quercetin | Diabetic Nephropathy | 10 | PM | 35889824 | 📋 | Investigation of the Renal Protective Effect of Combined Dietary Polyphenols in Streptozotocin-Induced Diabetic Aged Rats |
Quercetin | Diabetic Nephropathy | 9 | PM | 35615688 | 📋 | Investigating the Molecular Mechanism of Quercetin Protecting against Podocyte Injury to Attenuate Diabetic Nephropathy through Network Pharmacology, MicroarrayData Analysis, and Molecular Docking |
Quercetin | Diabetic Nephropathy | 8 | PM | 35416188 | 📋 | The effect of quercetin on diabetic nephropathy (DN): a systematic review and meta-analysis of animal studies |
Quercetin | Diabetic Nephropathy | 7 | PM | 35248552 | 📋 | Preclinical evidence of the effect of quercetin on diabetic nephropathy: A meta-analysis of animal studies |
Quercetin | Diabetic Nephropathy | 6 | PM | 35129398 | 📋 | Quercetin attenuates the proliferation, inflammation, and oxidative stress of high glucose-induced human mesangial cells by regulating the miR-485-5p/YAP1 pathway |
Quercetin | Diabetic Nephropathy | 5 | PM | 35069207 | 📋 | Quercetin Attenuates Podocyte Apoptosis of Diabetic Nephropathy Through Targeting EGFR Signaling |
Quercetin | Diabetic Nephropathy | 4 | PM | 34922902 | 📋 | The potential therapeutic effects of Trifolium alexandrinum extract, hesperetin and quercetin against diabetic nephropathy via attenuation of oxidative stress, inflammation, GSK-3β and apoptosis in male rats |
Quercetin | Diabetic Nephropathy | 3 | PM | 34273031 | 📋 | Protective effects of Quercetin and Resveratrol on aging markers in kidney under high glucose condition: in vivo and in vitro analysis |
Quercetin | Diabetic Nephropathy | 2 | PM | 32051470 | 📋 | Quercetin Liposomes Ameliorate Streptozotocin-Induced Diabetic Nephropathy in Diabetic Rats |
Quercetin | Diabetic Nephropathy | 1 | PM | 15053821 | 📋 | Quercetin, an Anti-Oxidant Bioflavonoid, Attenuates Diabetic Nephropathy in Rats |
Quercetin | Diabetic Neuropathy | 7 | PM | 38534744 | 📋 | An Examination of the Effects of Propolis and Quercetin in a Rat Model of Streptozotocin-Induced Diabetic Peripheral Neuropathy |
Quercetin | Diabetic Neuropathy | 5 | PM | 34743981 | 📋 | Quercetin reduces inflammation in a rat model of diabetic peripheral neuropathy by regulating the TLR4/MyD88/NF-κB signalling pathway |
Quercetin | Diabetic Neuropathy | 6 | PM | 33746703 | 📋 | Quercetin Attenuates Diabetic Peripheral Neuropathy by Correcting Mitochondrial Abnormality via Activation of AMPK/PGC-1α Pathway in vivo and in vitro |
Quercetin | Diabetic Neuropathy | 4 | PM | 32559841 | 📋 | Protective Effect of Quercetin on Streptozotocin-Induced Diabetic Peripheral Neuropathy Rats Through Modulating Gut Microbiota and Reactive Oxygen Species Level |
Quercetin | Diabetic Neuropathy | 3 | PM | 32553736 | 📋 | Quercetin Attenuates Diabetic Neuropathic Pain by Inhibiting mTOR/p70S6K Pathway-Mediated Changes of Synaptic Morphology and Synaptic Protein Levels in Spinal Dorsal Horn of db/db Mice |
Quercetin | Diabetic Neuropathy | 2 | PM | 28861887 | 📋 | Combination of Quercetin, Cinnamaldehyde and Hirudin Protects Rat Dorsal Root Ganglion Neurons Against High Glucose-Induced Injury Through Nrf-2/HO-1 Activation and NF-κB Inhibition |
Quercetin | Diabetic Neuropathy | 1 | PM | 16112498 | 📋 | A Multicenter, Double-Blind, Safety Study of QR-333 for the Treatment of Symptomatic Diabetic Peripheral Neuropathy. A Preliminary Report |
Quercetin | Diabetic Retinopathy | 5 | PM | 38185061 | 📋 | Quercetin protects against hyperglycemia-induced retinopathy in Sprague Dawley rats by regulating the gut-retina axis and nuclear factor erythroid-2-related factor 2 pathway |
Quercetin | Diabetic Retinopathy | 3 | PM | 36091769 | 📋 | Senolytics in the treatment of diabetic retinopathy |
Quercetin | Diabetic Retinopathy | 4 | PM | 33469482 | 📋 | Effects of quercetin on diabetic retinopathy and its association with NLRP3 inflammasome and autophagy |
Quercetin | Diabetic Retinopathy | 2 | PM | 29285153 | 📋 | Effects of Quercetin on the Expression of MCP-1, MMP-9 and VEGF in Rats With Diabetic Retinopathy |
Quercetin | Diabetic Retinopathy | 1 | PM | 28855811 | 📋 | Neuroprotective Effects of Quercetin in Diabetic Rat Retina |
Quercetin | Diabetic Ulcers and Sores | 3 | PM | 38308387 | 📋 | Management of wounds in diabetes by administering allicin and quercetin in emulsion form as wound medicine in diabetic rat models |
Quercetin | Diabetic Ulcers and Sores | 2 | PM | 35105256 | 📋 | Acceleration of wound healing by quercetin in diabetic rats requires mitigation of oxidative stress and stimulation of the proliferative phase |
Quercetin | Diabetic Ulcers and Sores | 1 | PM | 34278923 | 📋 | Topical application of quercetin improves wound repair and regeneration in diabetic rats |
Quercetin | Diabetic Vasculopathy | 2 | PM | 33395297 | 📋 | Quercetin Attenuated Myeloperoxidase-Dependent HOCl Generation and Endothelial Dysfunction in Diabetic Vasculature |
Quercetin | Diabetic Vasculopathy | 1 | PM | 32768953 | 📋 | Plant polyphenols Morin and Quercetin rescue nitric oxide production in diabetic mouse aorta through distinct pathways |
Quercetin | Gestational Diabetes | 1 | PM | 33640737 | 📋 | Quercetin improved histological structure and upregulated adiponectin and adiponectin receptors in the placenta of rats with gestational diabetes mellitus |
Quercetin | Hyperglycemia | 8 | PM | 36907948 | 📋 | Enhanced hypoglycemic bioactivity via RAS/Raf-1/MEK/ERK signaling pathway by combining capsaicin and QUERCETIN from chili peppers |
Quercetin | Hyperglycemia | 7 | PM | 36115306 | 📋 | Structure-activity relationships and the underlying mechanism of α-amylase inhibition by hyperoside and quercetin: Multi-spectroscopy and molecular docking analyses |
Quercetin | Hyperglycemia | 6 | PM | 35124182 | 📋 | Enhanced alleviation of insulin resistance via the IRS-1/Akt/FOXO1 pathway by combining quercetin and EGCG and involving miR-27a-3p and miR-96-5p |
Quercetin | Hyperglycemia | 5 | PM | 34046323 | 📋 | Protective effects of quercetin against hyperglycemia-induced oxidative stress in hepatic HepG2 cell line |
Quercetin | Hyperglycemia | 4 | PM | 32801472 | 📋 | Prevention effect of quercetin and its glycosides on obesity and hyperglycemia through activating AMPKα in high-fat diet-fed ICR mice |
Quercetin | Hyperglycemia | 3 | PM | 32104545 | 📋 | The Effects and Mechanism of Quercetin Dietary Supplementation in Streptozotocin-Induced Hyperglycemic Arbor Acre Broilers |
Quercetin | Hyperglycemia | 2 | PM | 31876980 | 📋 | Quercetin Modulates Hyperglycemia by Improving the Pancreatic Antioxidant Status and Enzymes Activities Linked With Glucose Metabolism in Type 2 Diabetes Model of Rats: In Silico Studies of Molecular Interaction of Quercetin With Hexokinase and Catalase |
Quercetin | Hyperglycemia | 1 | PM | 29736297 | 📋 | Anti-diabetic Activity of Quercetin Extracted From Phyllanthus emblica L. Fruit: In silico and in vivo Approaches |
Quercetin | Postprandial Hyperglycemia | 1 | PM | 37674537 | 📋 | Study on Optimal Extraction and Hypoglycemic Effect of Quercetin |