| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Coptis Chinensis | Diabetes | 3 | PM | 30544908 | 📋 | UPLC-Q/TOF-MS-Based Serum Metabolomics Reveals Hypoglycemic Effects of Rehmannia glutinosa, Coptis chinensis and Their Combination on High-Fat-Diet-Induced Diabetes in KK-Ay Mice |
| Coptis Chinensis | Diabetes | 2 | PM | 27093269 | 📋 | Coptis chinensis Polysaccharides Inhibit Advanced Glycation End Product Formation |
| Coptis Chinensis | Diabetes | 4 | PM | 26508987 | 📋 | Effect of Rhizoma coptidis (Huang Lian) on Treating Diabetes Mellitus |
| Coptis Chinensis | Diabetes | 1 | PM | 23295205 | 📋 | Anti-diabetic effect of Coptis Chinensis polysaccharide in high-fat diet with STZ-induced diabetic mice |
| Coptis Chinensis | Diabetes Type 2 | 2 | PM | 34675276 | 📋 | Mechanisms of Rhizoma Coptidis against type 2 diabetes mellitus explored by network pharmacology combined with molecular docking and experimental validation |
| Coptis Chinensis | Diabetes Type 2 | 1 | PM | 34581092 | 📋 | [Mechanism of Astragali Radix-Coptis Rhizoma pair in treating type 2 diabetes mellitus based on network pharmacology] |
| Coptis Chinensis | Diabetes Type 2 | 10 | PM | 33568997 | 📋 | Effective Dose of Rhizoma Coptidis Extract Granules for Type 2 Diabetes Treatment: A Hospital-Based Retrospective Cohort Study |
| Coptis Chinensis | Diabetes Type 2 | 4 | PM | 32730886 | 📋 | Study on the mechanism of Gegen Qinlian Decoction for treating type II diabetes mellitus by integrating network pharmacology and pharmacological evaluation |
| Coptis Chinensis | Diabetes Type 2 | 3 | PM | 31758238 | 📋 | Scutellariae radix and coptidis rhizoma ameliorate glycolipid metabolism of type 2 diabetic rats by modulating gut microbiota and its metabolites |
| Coptis Chinensis | Diabetes Type 2 | 11 | PM | 31396083 | 📋 | Rhizoma coptidis as a Potential Treatment Agent for Type 2 Diabetes Mellitus and the Underlying Mechanisms: A Review |
| Coptis Chinensis | Diabetes Type 2 | 9 | PM | 30453687 | 📋 | Scutellariae Radix and Coptidis Rhizoma Improve Glucose and Lipid Metabolism in T2DM Rats via Regulation of the Metabolic Profiling and MAPK/PI3K/Akt Signaling Pathway |
| Coptis Chinensis | Diabetes Type 2 | 5 | PM | 28901416 | 📋 | Protective role of berberine and Coptischinensis extract on T2MD rats and associated islet Rin‑5f cells |
| Coptis Chinensis | Diabetes Type 2 | 8 | PM | 27261584 | 📋 | The inhibiting effect of the Coptis chinensis polysaccharide on the type II diabetic mice |
| Coptis Chinensis | Diabetes Type 2 | 7 | PM | 25858018 | 📋 | Antidiabetic mechanism of Coptis chinensis polysaccharide through its antioxidant property involving the JNK pathway |
| Coptis Chinensis | Diabetes Type 2 | 6 | PM | 22667084 | 📋 | [Exploring the mechanism of rhizoma coptidis in treating type II diabetes mellitus based on metabolomics by gas chromatography-mass spectrometry] |
| Coptis Chinensis | Diabetic Encephalopathy | 1 | PM | 30214157 | 📋 | The total alkaloids from Coptis chinensis Franch improve cognitive deficits in type 2 diabetic rats |
| Coptis Chinensis | Diabetic Nephropathy | 1 | PM | 34114400 | 📋 | Full composition granules of Huanglian (Rhizoma Coptidis) decrease the serum monocyte chemotactic protein-1 and connective tissue growth factor levels and inhibit kidney nuclear factor-κB expression in rats with high-fat diet-induced diabete |
| Coptis Chinensis | Diabetic Nephropathy | 2 | PM | 29378192 | 📋 | Berberine attenuates podocytes injury caused by exosomes derived from high glucose-induced mesangial cells through TGFβ1-PI3K/AKT pathway |
| Coptis Chinensis | Diabetic Neuropathy | 1 | PM | 33444721 | 📋 | An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy |
| Coptis Chinensis | Diabetic Vasculopathy | 1 | PM | 34299486 | 📋 | Coptisine Attenuates Diabetes-Associated Endothelial Dysfunction through Inhibition of Endoplasmic Reticulum Stress and Oxidative Stress |
| Coptis Chinensis | Hyperglycemia | 3 | PM | 35187178 | 📋 | Shenlian (SL) Decoction, a Traditional Chinese Medicine Compound, May Ameliorate Blood Glucose via Mediating the Gut Microbiota in db/db Mice |
| Coptis Chinensis | Hyperglycemia | 2 | PM | 34380455 | 📋 | Obese rats intervened with Rhizoma coptidis revealed differential gene expression and microbiota by serum metabolomics |
| Coptis Chinensis | Hyperglycemia | 1 | PM | 34211397 | 📋 | Blood-Glucose-Lowering Effect of Coptidis Rhizoma Extracts From Different Origins via Gut Microbiota Modulation in db/db Mice |
| Coptis Chinensis | Hyperglycemia | 5 | PM | 30836124 | 📋 | The anti-hyperglycemia effects of Rhizoma Coptidis alkaloids: A systematic review of modern pharmacological studies of the traditional herbal medicine |
| Coptis Chinensis | Hyperglycemia | 4 | PM | 24818152 | 📋 | The antihyperglycemic effects of Rhizoma Coptidis and mechanism of actions: a review of systematic reviews and pharmacological research |
