| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Astragalosides | Alzheimer's Disease | 13 | PM | 38412923 | 📋 | Icariin, astragaloside a and puerarin mixture attenuates cognitive impairment in APP/PS1 mice via inhibition of ferroptosis-lipid peroxidation |
| Astragalosides | Alzheimer's Disease | 11 | PM | 37598923 | 📋 | Astragaloside IV against Alzheimer's disease via microglia-mediated neuroinflammation using network pharmacology and experimental validation |
| Astragalosides | Alzheimer's Disease | 10 | PM | 36820018 | 📋 | Astragaloside IV attenuates neuroinflammation and ameliorates cognitive impairment in Alzheimer's disease via inhibiting NF-κB signaling pathway |
| Astragalosides | Alzheimer's Disease | 9 | PM | 35262870 | 📋 | Exercise Rehabilitation and/or Astragaloside Attenuate Amyloid-beta Pathology by Reversing BDNF/TrkB Signaling Deficits and Mitochondrial Dysfunction |
| Astragalosides | Alzheimer's Disease | 7 | PM | 34616501 | 📋 | Depichering the Effects of Astragaloside IV on AD-Like Phenotypes: A Systematic and Experimental Investigation |
| Astragalosides | Alzheimer's Disease | 6 | PM | 34433707 | 📋 | Astragaloside IV ameliorates cognitive impairment and neuroinflammation in an oligomeric Aβ induced Alzheimer's disease mouse model via inhibition of microglial activation and NADPH oxidase expression |
| Astragalosides | Alzheimer's Disease | 5 | PM | 32739157 | 📋 | Astragaloside IV prevents Aβ 1-42 oligomers-induced memory impairment and hippocampal cell apoptosis by promoting PPARγ/BDNF signaling pathway |
| Astragalosides | Alzheimer's Disease | 8 | PM | 31816602 | 📋 | Active compounds of herbs ameliorate impaired cognition in APP/PS1 mouse model of Alzheimer's disease |
| Astragalosides | Alzheimer's Disease | 4 | PM | 30664172 | 📋 | Astragaloside IV Ameliorates Endoplasmic Reticulum stress‑induced Apoptosis of Aβ25‑35‑treated PC12 Cells by Inhibiting the p38 MAPK Signaling Pathway |
| Astragalosides | Alzheimer's Disease | 2 | PM | 29620512 | 📋 | Astragaloside Ⅳ Protects Against Aβ1-42-induced Oxidative Stress, Neuroinflammation and Cognitive Impairment in Rats |
| Astragalosides | Alzheimer's Disease | 1 | PM | 27023226 | 📋 | Astragaloside IV, a Natural PPARγ Agonist, Reduces Aβ Production in Alzheimer's Disease Through Inhibition of BACE1 |
| Astragalosides | Alzheimer's Disease | 3 | PM | 26696494 | 📋 | Beneficial Effect of Astragaloside on Alzheimer's Disease Condition Using Cultured Primary Cortical Cells Under β-amyloid Exposure |
| Astragalosides | Alzheimer's Disease | 12 | PM | 22484447 | 📋 | Protective effects of astragalosides on dexamethasone and Aβ25-35 induced learning and memory impairments due to decrease amyloid precursor protein expression in 12-month male rats |
| Astragalosides | Dementia | 1 | PM | 32963600 | 📋 | CGA ameliorates cognitive decline by regulating the PI3K/AKT signaling pathway and neurotransmitter systems in rats with multi-infarct dementia |
| Astragalosides | Parkinson's Disease | 8 | PM | 37603153 | 📋 | Astragaloside IV Inhibits Rotenone-Induced α-syn Presentation and the CD4 T-Cell Immune Response |
| Astragalosides | Parkinson's Disease | 7 | PM | 34994139 | 📋 | [Mechanism of astragaloside Ⅳ alleviating PC12 cell injury by activating PI3K/AKT signaling pathway: based on network pharmacology and in vitro experiments] |
| Astragalosides | Parkinson's Disease | 5 | PM | 33833662 | 📋 | Astragaloside IV Protects 6-Hydroxydopamine-Induced SH-SY5Y Cell Model of Parkinson's Disease via Activating the JAK2/STAT3 Pathway |
| Astragalosides | Parkinson's Disease | 6 | PM | 32511947 | 📋 | Astragaloside-IV regulates endoplasmic reticulum stress-mediated neuronal apoptosis in a murine model of Parkinson's disease via the lincRNA-p21/CHOP pathway |
| Astragalosides | Parkinson's Disease | 1 | PM | 32252767 | 📋 | Astragaloside IV Inhibits Astrocyte Senescence: Implication in Parkinson's Disease |
| Astragalosides | Parkinson's Disease | 2 | PM | 31401385 | 📋 | Astragaloside IV Ameliorates Motor Deficits and Dopaminergic Neuron Degeneration via Inhibiting Neuroinflammation and Oxidative Stress in a Parkinson's Disease Mouse Model |
| Astragalosides | Parkinson's Disease | 10 | PM | 29285094 | 📋 | Neuroprotective effects of astragaloside IV on Parkinson disease models of mice and primary astrocytes |
| Astragalosides | Parkinson's Disease | 3 | PM | 29039448 | 📋 | Astragaloside IV Attenuates the H2O2-induced Apoptosis of Neuronal Cells by Inhibiting α-synuclein Expression via the p38 MAPK Pathway |
| Astragalosides | Parkinson's Disease | 4 | PM | 28962208 | 📋 | Astragaloside IV Rescues MPP +-induced Mitochondrial Dysfunction Through Upregulation of Methionine Sulfoxide Reductase A |
| Astragalosides | Parkinson's Disease | 9 | PM | 22278385 | 📋 | Astragaloside IV prevents MPP⁺-induced SH-SY5Y cell death via the inhibition of Bax-mediated pathways and ROS production |
| Astragalosides | Vascular Dementia | 1 | PM | 37209830 | 📋 | Astragaloside IV ameliorates cognitive impairment and protects oligodendrocytes from antioxidative stress via regulation of the SIRT1/Nrf2 signaling pathway |
