| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| TUDCA | Abdominal Aortic Aneurysm | 1 | PM | 27889204 | 📋 | Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress |
| TUDCA | Acclimatization To Altitude | 1 | PM | 38518722 | 📋 | Exploring the impact of high-altitude de-acclimatization on renal function: The roles of oxidative and endoplasmic reticulum stress in rat models |
| TUDCA | Aortic Valve Stenosis | 1 | PM | 23928865 | 📋 | Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals |
| TUDCA | Arterial Restenosis | 1 | PM | 30663009 | 📋 | The Role of Tauroursodeoxycholic Acid on Dedifferentiation of Vascular Smooth Muscle Cells by Modulation of Endoplasmic Reticulum Stress and as an Oral Drug Inhibiting In-Stent Restenosis |
| TUDCA | Arterial Restenosis | 2 | PM | 25373918 | 📋 | Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury |
| TUDCA | Arterial Stiffness | 2 | PM | 32196361 | 📋 | Endothelial calreticulin deletion impairs endothelial function in aged mice |
| TUDCA | Arterial Stiffness | 1 | PM | 28930750 | 📋 | Tauroursodeoxycholic Acid Reduces Arterial Stiffness and Improves Endothelial Dysfunction in Type 2 Diabetic Mice |
| TUDCA | Atherosclerosis | 1 | PM | 38784008 | 📋 | TUDCA alleviates atherosclerosis by inhibiting AIM2 inflammasome and enhancing cholesterol efflux capacity in macrophage |
| TUDCA | Cardiovascular Disease | 1 | PM | 30038553 | 📋 | Tauroursodeoxycholic Acid Alleviates H2O2-Induced Oxidative Stress and Apoptosis via Suppressing Endoplasmic Reticulum Stress in Neonatal Rat Cardiomyocytes |
| TUDCA | Cerebral Ischemia-Reperfusion | 1 | PM | 29375691 | 📋 | Synergistic neuroprotective effects of Geniposide and ursodeoxycholic acid in hypoxia-reoxygenation injury in SH-SY5Y cells |
| TUDCA | Diabetic Cardiomyopathy | 1 | PM | 29174818 | 📋 | Inhibition of advanced glycation endproduct (AGE) rescues against streptozotocin-induced diabetic cardiomyopathy: Role of autophagy and ER stress |
| TUDCA | Diabetic Vasculopathy | 2 | PM | 28930750 | 📋 | Tauroursodeoxycholic Acid Reduces Arterial Stiffness and Improves Endothelial Dysfunction in Type 2 Diabetic Mice |
| TUDCA | Diabetic Vasculopathy | 1 | PM | 26234558 | 📋 | Diabetes and Age-Related Differences in Vascular Function of Renal Artery: Possible Involvement of Endoplasmic Reticulum Stress |
| TUDCA | Endothelial Dysfunction | 6 | PM | 32196361 | 📋 | Endothelial calreticulin deletion impairs endothelial function in aged mice |
| TUDCA | Endothelial Dysfunction | 5 | PM | 30458302 | 📋 | Inhibition of endoplasmic reticulum stress protected DOCA-salt hypertension-induced vascular dysfunction |
| TUDCA | Endothelial Dysfunction | 4 | PM | 28562691 | 📋 | Chronic treatment with paeonol improves endothelial function in mice through inhibition of endoplasmic reticulum stress-mediated oxidative stress |
| TUDCA | Endothelial Dysfunction | 3 | PM | 27503949 | 📋 | Administration of tauroursodeoxycholic acid prevents endothelial dysfunction caused by an oral glucose load |
| TUDCA | Endothelial Dysfunction | 2 | PM | 26522062 | 📋 | Toll-like receptor 4-induced endoplasmic reticulum stress contributes to impairment of vasodilator action of insulin |
| TUDCA | Endothelial Dysfunction | 1 | PM | 25623775 | 📋 | The role of endoplasmic reticulum stress in endothelial dysfunction induced by homocysteine thiolactone |
| TUDCA | Endothelial Injury | 1 | PM | 25407160 | 📋 | Tauroursodeoxycholic acid, a bile acid, promotes blood vessel repair by recruiting vasculogenic progenitor cells |
| TUDCA | Heart Disease | 1 | PM | 23667647 | 📋 | Tauroursodeoxycholic acid mitigates high fat diet-induced cardiomyocyte contractile and intracellular Ca2+ anomalies |
| TUDCA | Heart Failure | 1 | PM | 33307852 | 📋 | Inhibition of Brainstem Endoplasmic Reticulum Stress Rescues Cardiorespiratory Dysfunction in High Output Heart Failure |
| TUDCA | Hemorrhagic Shock | 1 | PM | 30998645 | 📋 | TUDCA Ameliorates Liver Injury Via Activation of SIRT1-FXR Signaling in a Rat Hemorrhagic Shock Model |
| TUDCA | Hemorrhagic Shock | 2 | PM | 30499877 | 📋 | Modulation of Endoplasmic Reticulum Stress Influences Ischemia-Reperfusion Injury After Hemorrhagic Shock |
| TUDCA | Hemorrhagic Stroke | 1 | PM | 32880859 | 📋 | Inhibiting ER Stress Weakens Neuronal Pyroptosis in a Mouse Acute Hemorrhagic Stroke Model |
| TUDCA | Hepatic Ischemia-Reperfusion | 1 | PM | 30119197 | 📋 | Tauroursodeoxycholic acid alleviates hepatic ischemia reperfusion injury by suppressing the function of Kupffer cells in mice |
| TUDCA | Hypertension | 2 | PM | 32072406 | 📋 | Reversal of deleterious effect of hypertension on the liver by inhibition of endoplasmic reticulum stress |
| TUDCA | Hypertension | 1 | PM | 31579948 | 📋 | Hypertension-induced cardiac impairment is reversed by the inhibition of endoplasmic reticulum stress |
| TUDCA | Hypertension | 4 | PM | 30458302 | 📋 | Inhibition of endoplasmic reticulum stress protected DOCA-salt hypertension-induced vascular dysfunction |
| TUDCA | Hypertension | 3 | PM | 27550383 | 📋 | Inhibition of endoplasmic reticulum stress improves coronary artery function in the spontaneously hypertensive rats |
| TUDCA | Intimal Hyperplasia | 1 | PM | 21840882 | 📋 | Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK via PKCα-mediated MKP-1 induction |
| TUDCA | Intracerebral Hemorrhage | 1 | PM | 28544790 | 📋 | Roles of autophagy and endoplasmic reticulum stress in intracerebral hemorrhage-induced secondary brain injury in rats |
| TUDCA | Ischemia-Reperfusion Injuries | 1 | PM | 27904664 | 📋 | Tauroursodeoxycholic acid inhibits endoplasmic reticulum stress, blocks mitochondrial permeability transition pore opening, and suppresses reperfusion injury through GSK-3ß in cardiac H9c2 cells |
| TUDCA | Myocardial Fibrosis | 1 | PM | 31579948 | 📋 | Hypertension-induced cardiac impairment is reversed by the inhibition of endoplasmic reticulum stress |
| TUDCA | Myocardial Fibrosis | 2 | PM | 27441395 | 📋 | Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis |
| TUDCA | Myocardial Infarction | 1 | PM | 29288332 | 📋 | Essential role for EGFR tyrosine kinase and ER stress in myocardial infarction in type 2 diabetes |
| TUDCA | Myocardial Ischemia-Reperfusion | 2 | PM | 29391923 | 📋 | Roles of Endoplasmic Reticulum Stress in NECA-Induced Cardioprotection against Ischemia/Reperfusion Injury |
| TUDCA | Myocardial Ischemia-Reperfusion | 1 | PM | 26922713 | 📋 | Endoplasmic reticulum stress as a novel inducer of hypoxia inducible factor-1 activity: its role in the susceptibility to myocardial ischemia-reperfusion induced by chronic intermittent hypoxia |
| TUDCA | Stroke | 1 | PM | 30657576 | 📋 | DCA can improve the ACI-induced neurological impairment through negative regulation of Nrf2 signaling pathway |
| TUDCA | Subarachnoid Hemorrhage | 1 | PM | 33261652 | 📋 | Tauroursodeoxycholic acid attenuates neuronal apoptosis via the TGR5/ SIRT3 pathway after subarachnoid hemorrhage in rats |
| TUDCA | Subarachnoid Hemorrhage | 2 | PM | 31778648 | 📋 | Tauroursodeoxycholic acid prevents ER stress-induced apoptosis and improves cerebral and vascular function in mice subjected to subarachnoid hemorrhage |
| TUDCA | Thrombosis | 1 | PM | 32104390 | 📋 | Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex |
| TUDCA | Vascular Disorders | 1 | PM | 30458302 | 📋 | Inhibition of endoplasmic reticulum stress protected DOCA-salt hypertension-induced vascular dysfunction |
| TUDCA | Vascular Injury | 1 | PM | 25373918 | 📋 | Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury |
