| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Salvianolic Acid | Aortic Aneurysm | 1 | PM | 27663582 | 📋 | Amelioration of salvianolic acid C on aortic structure in apolipoprotein E-deficient mice treated with angiotension II |
| Salvianolic Acid | Aortic Aneurysm | 2 | PM | 24916705 | 📋 | Salvianolic acid A, a matrix metalloproteinase-9 inhibitor of Salvia miltiorrhiza, attenuates aortic aneurysm formation in apolipoprotein E-deficient mice |
| Salvianolic Acid | Atherosclerosis | 12 | PM | 37572566 | 📋 | Salvianolic acid B inhibits atherosclerosis and TNF-α-induced inflammation by regulating NF-κB/NLRP3 signaling pathway |
| Salvianolic Acid | Atherosclerosis | 11 | PM | 36804757 | 📋 | Salvianolic acid A alleviates atherosclerosis by inhibiting inflammation through Trc8-mediated 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation |
| Salvianolic Acid | Atherosclerosis | 10 | PM | 36758912 | 📋 | Salvianolic acid A attenuates inflammation-mediated atherosclerosis by suppressing GRP78 secretion of endothelial cells |
| Salvianolic Acid | Atherosclerosis | 9 | PM | 36425580 | 📋 | Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis |
| Salvianolic Acid | Atherosclerosis | 8 | PM | 36031232 | 📋 | Effect of astragaloside IV and salvianolic acid B on antioxidant stress and vascular endothelial protection in the treatment of atherosclerosis based on metabonomics |
| Salvianolic Acid | Atherosclerosis | 7 | PM | 35974091 | 📋 | Salvianolic acid B inhibits RAW264.7 cell polarization towards the M1 phenotype by inhibiting NF-κB and Akt/mTOR pathway activation |
| Salvianolic Acid | Atherosclerosis | 6 | PM | 35842645 | 📋 | Identification of core genes associated with the anti-atherosclerotic effects of Salvianolic acid B and immune cell infiltration characteristics using bioinformatics analysis |
| Salvianolic Acid | Atherosclerosis | 4 | PM | 35340217 | 📋 | Salvianolic Acid B Suppresses ER Stress-Induced NLRP3 Inflammasome and Pyroptosis via the AMPK/FoxO4 and Syndecan-4/Rac1 Signaling Pathways in Human Endothelial Progenitor Cells |
| Salvianolic Acid | Atherosclerosis | 3 | PM | 35285334 | 📋 | Salvianolic acid B attenuates the inflammatory response in atherosclerosis by regulating MAPKs/ NF-κB signaling pathways in LDLR-/- mice and RAW264.7 cells |
| Salvianolic Acid | Atherosclerosis | 2 | PM | 35194776 | 📋 | Salvianolic acid B inhibiting chemically and mechanically activated Piezo1 channels as a mechanism for ameliorating atherosclerosis |
| Salvianolic Acid | Atherosclerosis | 5 | PM | 34490483 | 📋 | Salvianolic acid B improves autophagic dysfunction and decreases the apoptosis of cholesterol crystal‑induced macrophages via inhibiting the Akt/mTOR signaling pathway |
| Salvianolic Acid | Atherosclerosis | 1 | PM | 32121151 | 📋 | Salvianolic Acid A Ameliorates Early-Stage Atherosclerosis Development by Inhibiting NLRP3 Inflammasome Activation in Zucker Diabetic Fatty Rats |
| Salvianolic Acid | Buerger's Disease | 1 | PM | 31790900 | 📋 | Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats |
| Salvianolic Acid | Cardiac Arrest | 1 | PM | 32714485 | 📋 | Salvianolic Acid B Improves Postresuscitation Myocardial and Cerebral Outcomes in a Murine Model of Cardiac Arrest: Involvement of Nrf2 Signaling Pathway |
| Salvianolic Acid | Cardiomyopathy | 1 | PM | 35782566 | 📋 | Changes in Cardiac Function During the Development of Uremic Cardiomyopathy and the Effect of Salvianolic Acid B Administration in a Rat Model |
| Salvianolic Acid | Cardiotoxicity | 2 | PM | 34153024 | 📋 | Salvianolic Acid A Protects H9C2 Cardiomyocytes from Doxorubicin-Induced Damage by Inhibiting NFKB1 Expression Thereby Downregulating Long-Noncoding RNA (lncRNA) Plasmacytoma Variant Translocation 1 (PVT1) |
| Salvianolic Acid | Cardiotoxicity | 1 | PM | 33952797 | 📋 | Salvianolic acid B attenuated cisplatin-induced cardiac injury and oxidative stress via modulating Nrf2 signal pathway |
| Salvianolic Acid | Cardiovascular Disease | 1 | PM | 37331452 | 📋 | Salvianolic acids from Salvia miltiorrhiza Bunge and their anti-inflammatory effects through the activation of α7nAchR signaling |
| Salvianolic Acid | Cerebral Ischemia | 5 | PM | 38468280 | 📋 | Salvianolic acid C attenuates cerebral ischemic injury through inhibiting neuroinflammation via the TLR4-TREM1-NF-κB pathway |
| Salvianolic Acid | Cerebral Ischemia | 4 | PM | 37708947 | 📋 | The potential effect of salvianolic acid B against rat ischemic brain injury in combination with mesenchymal stem cells |
| Salvianolic Acid | Cerebral Ischemia | 1 | PM | 34800628 | 📋 | Salvianolic Acid A Relieves Cognitive Disorder after Chronic Cerebral Ischemia: Involvement of Drd2/Cryab/NF-κB Pathway |
| Salvianolic Acid | Cerebral Ischemia | 2 | PM | 29180227 | 📋 | Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury |
| Salvianolic Acid | Cerebral Ischemia | 3 | PM | 17882954 | 📋 | [Effect of salvianolic acid B on neural cells damage and neurogenesis after brain ischemia-reperfusion in rats] |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 9 | PM | 38185068 | 📋 | Salvianolic acid A provides neuroprotective effects on cerebral ischemia-reperfusion injury in rats via PKA/CREB/c-Fos signaling pathway |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 8 | PM | 37987200 | 📋 | Salvianolic acid A improves nerve regeneration and repairs nerve defects in rats with brain injury by downregulating miR-212-3p-mediated SOX7 |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 7 | PM | 37904689 | 📋 | Neuroprotective mechanism of salvianolic acid B against cerebral ischemia-reperfusion injury in mice through downregulation of TLR4, p-p38MAPK, p-JNK, NF-κB, and IL-1β |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 6 | PM | 35810493 | 📋 | Salvianolic acid C improves cerebral ischemia reperfusion injury through suppressing microglial cell M1 polarization and promoting cerebral angiogenesis |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 3 | PM | 35136538 | 📋 | Clinical Observation of Salvianolic Acid Combined with Panax Notoginseng Saponins Combined with Basic Nursing Intervention on Cerebral Ischemia-Reperfusion Injury in Rats |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 4 | PM | 33985878 | 📋 | Salvianolic acid A alleviated inflammatory response mediated by microglia through inhibiting the activation of TLR2/4 in acute cerebral ischemia-reperfusion |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 5 | PM | 33421597 | 📋 | Salvianolic Acids for Injection alleviates cerebral ischemia/reperfusion injury by switching M1/M2 phenotypes and inhibiting NLRP3 inflammasome/pyroptosis axis in microglia in vivo and in vitro |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 1 | PM | 32774700 | 📋 | Salvianolic acid A attenuates cerebral ischemia/reperfusion injury induced rat brain damage, inflammation and apoptosis by regulating miR-499a/DDK1 |
| Salvianolic Acid | Cerebral Ischemia-Reperfusion | 2 | PM | 31193821 | 📋 | Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of salvianolic acid A against cerebral ischemia/reperfusion injury |
| Salvianolic Acid | Coronary Artery Disease | 1 | PM | 34597652 | 📋 | Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling |
| Salvianolic Acid | Diabetic Cardiomyopathy | 3 | PM | 38072948 | 📋 | Salvianolic acid B ameliorates myocardial fibrosis in diabetic cardiomyopathy by deubiquitinating Smad7 |
| Salvianolic Acid | Diabetic Cardiomyopathy | 2 | PM | 36773525 | 📋 | Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy |
| Salvianolic Acid | Diabetic Cardiomyopathy | 1 | PM | 36035917 | 📋 | Perspectives for Forkhead box transcription factors in diabetic cardiomyopathy: Their therapeutic potential and possible effects of salvianolic acids |
| Salvianolic Acid | Diabetic Vasculopathy | 5 | PM | 38405620 | 📋 | Salvianolic Acid B Alleviates High Glucose-Induced Vascular Smooth Muscle Cell Inflammation by Upregulating the miR-486a-5p Expression |
| Salvianolic Acid | Diabetic Vasculopathy | 4 | PM | 36425580 | 📋 | Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis |
| Salvianolic Acid | Diabetic Vasculopathy | 1 | PM | 35761806 | 📋 | Salvianolic acid A promotes mitochondrial biogenesis and function via regulating the AMPK/PGC-1α signaling pathway in HUVECs |
| Salvianolic Acid | Diabetic Vasculopathy | 2 | PM | 35068334 | 📋 | Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells |
| Salvianolic Acid | Diabetic Vasculopathy | 3 | PM | 34637797 | 📋 | Salvianolic acid B ameliorates vascular endothelial dysfunction through influencing a bone morphogenetic protein 4-ROS cycle in diabetic mice |
| Salvianolic Acid | Endothelial Dysfunction | 5 | PM | 38789509 | 📋 | Salvianolic acid A alleviates H2O2-induced endothelial oxidative injury via miR-204-5p |
| Salvianolic Acid | Endothelial Dysfunction | 4 | PM | 36031232 | 📋 | Effect of astragaloside IV and salvianolic acid B on antioxidant stress and vascular endothelial protection in the treatment of atherosclerosis based on metabonomics |
| Salvianolic Acid | Endothelial Dysfunction | 2 | PM | 35340217 | 📋 | Salvianolic Acid B Suppresses ER Stress-Induced NLRP3 Inflammasome and Pyroptosis via the AMPK/FoxO4 and Syndecan-4/Rac1 Signaling Pathways in Human Endothelial Progenitor Cells |
| Salvianolic Acid | Endothelial Dysfunction | 1 | PM | 35068334 | 📋 | Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells |
| Salvianolic Acid | Endothelial Dysfunction | 3 | PM | 34637797 | 📋 | Salvianolic acid B ameliorates vascular endothelial dysfunction through influencing a bone morphogenetic protein 4-ROS cycle in diabetic mice |
| Salvianolic Acid | Heart Failure | 2 | PM | 37931518 | 📋 | Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways |
| Salvianolic Acid | Heart Failure | 1 | PM | 36825182 | 📋 | Salvianolic acid D: A potent molecule that protects against heart failure induced by hypertension via Ras signalling pathway and PI3K/Akt signalling pathway |
| Salvianolic Acid | Hypertension | 2 | PM | 36121714 | 📋 | Salvianolic Acid Ameliorates Pressure Overload-Induced Cardiac Endothelial Dysfunction via Activating HIF1[Formula: see text]/HSF1/CD31 Pathway |
| Salvianolic Acid | Hypertension | 1 | PM | 35700852 | 📋 | Salvianolic acid A from Danhong Injection induces vasorelaxation by Regulating L-type calcium channel in isolated mouse arteries |
| Salvianolic Acid | Intestinal Ischemia-Reperfusion | 1 | PM | 37387514 | 📋 | Protective effects of salvianolic acid B on intestinal ischemia/reperfusion injury in rats by regulating the AhR/IL-22/STAT6 axis |
| Salvianolic Acid | Intracerebral Hemorrhage | 1 | PM | 38816543 | 📋 | Salvianolic acid A inhibits ferroptosis and protects against intracerebral hemorrhage |
| Salvianolic Acid | Ischemia-Reperfusion Injuries | 1 | PM | 38089048 | 📋 | Protective effects of Salvianic acid A against multiple-organ ischemia-reperfusion injury: a review |
| Salvianolic Acid | Ischemic Stroke | 7 | PM | 35957712 | 📋 | Salvianolic acid B alleviates neurological injury by upregulating stanniocalcin 1 expression |
| Salvianolic Acid | Ischemic Stroke | 4 | PM | 35217812 | 📋 | Long-term administration of salvianolic acid A promotes endogenous neurogenesis in ischemic stroke rats through activating Wnt3a/GSK3β/β-catenin signaling pathway |
| Salvianolic Acid | Ischemic Stroke | 3 | PM | 35153756 | 📋 | Network Pharmacology and Molecular Docking-Based Mechanism Study to Reveal the Protective Effect of Salvianolic Acid C in a Rat Model of Ischemic Stroke |
| Salvianolic Acid | Ischemic Stroke | 6 | PM | 34973964 | 📋 | Astrocytic glycogen mobilization participates in salvianolic acid B-mediated neuroprotection against reperfusion injury after ischemic stroke |
| Salvianolic Acid | Ischemic Stroke | 1 | PM | 34284451 | 📋 | Neurovascular protection of salvianolic acid B and ginsenoside Rg1 combination against acute ischemic stroke in rats |
| Salvianolic Acid | Ischemic Stroke | 5 | PM | 33303991 | 📋 | Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway |
| Salvianolic Acid | Ischemic Stroke | 2 | PM | 29498696 | 📋 | Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury |
| Salvianolic Acid | Left Ventricular Hypertrophy | 1 | PM | 34777543 | 📋 | Intraventricular pressure gradients change during the development of left ventricular hypertrophy: Effect of salvianolic acid B and beta-blocker |
| Salvianolic Acid | Lymphoma | 1 | PM | 33278489 | 📋 | Salvianolic acid A inhibits the growth of diffuse large B-cell lymphoma through MAPK pathways |
| Salvianolic Acid | Myocardial Fibrosis | 3 | PM | 38662612 | 📋 | SALVIANOLIC ACID A ATTENUATES ANGIOTENSIN II-INDUCED CARDIAC FIBROSIS THROUGH REGULATING THE TXNIP SIGNALING PATHWAY |
| Salvianolic Acid | Myocardial Fibrosis | 2 | PM | 37337901 | 📋 | Salvianolic acid A diminishes LDHA-driven aerobic glycolysis to restrain myofibroblasts activation and cardiac fibrosis via blocking Akt/GSK-3β/HIF-1α axis |
| Salvianolic Acid | Myocardial Fibrosis | 1 | PM | 35984595 | 📋 | Therapeutic Effects of Salvianolic Acid B on Angiotensin II-Induced Atrial Fibrosis by Regulating Atrium Metabolism via Targeting AMPK/FoxO1/miR-148a-3p Axis |
| Salvianolic Acid | Myocardial Infarction | 4 | PM | 36248430 | 📋 | Network Pharmacology Analyses of the Pharmacological Targets and Therapeutic Mechanisms of Salvianolic Acid A in Myocardial Infarction |
| Salvianolic Acid | Myocardial Infarction | 3 | PM | 36174419 | 📋 | Protective effects of Salvianolic acid B on rat ferroptosis in myocardial infarction through upregulating the Nrf2 signaling pathway |
| Salvianolic Acid | Myocardial Infarction | 5 | PM | 31811327 | 📋 | Salvianolic acid A attenuated myocardial infarction-induced apoptosis and inflammation by activating Trx |
| Salvianolic Acid | Myocardial Infarction | 1 | PM | 25476150 | 📋 | Ginsenoside Rg1 and Rb1, in Combination With Salvianolic Acid B, Play Different Roles in Myocardial Infarction in Rats |
| Salvianolic Acid | Myocardial Infarction | 2 | PM | 19643081 | 📋 | Salvianolic acid B-vitamin C synergy in cardiac differentiation from embryonic stem cells |
| Salvianolic Acid | Myocardial Injury | 2 | PM | 36121714 | 📋 | Salvianolic Acid Ameliorates Pressure Overload-Induced Cardiac Endothelial Dysfunction via Activating HIF1[Formula: see text]/HSF1/CD31 Pathway |
| Salvianolic Acid | Myocardial Injury | 1 | PM | 33762947 | 📋 | Inhibition of TLR4/MAPKs Pathway Contributes to the Protection of Salvianolic Acid A Against Lipotoxicity-Induced Myocardial Damage in Cardiomyocytes and Obese Mice |
| Salvianolic Acid | Myocardial Ischemia | 2 | PM | 38017536 | 📋 | Salvianolic acid B promotes angiogenesis and inhibits cardiomyocyte apoptosis by regulating autophagy in myocardial ischemia |
| Salvianolic Acid | Myocardial Ischemia | 1 | PM | 35809215 | 📋 | Salvianolic Acid B Alleviates Myocardial Ischemia Injury by Suppressing NLRP3 Inflammasome Activation via SIRT1-AMPK-PGC-1α Signaling Pathway |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 8 | PM | 38543095 | 📋 | Exploring the Mechanism of Salvianolic Acid B against Myocardial Ischemia-Reperfusion Injury Based on Network Pharmacology |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 7 | PM | 38360382 | 📋 | Study on therapeutic mechanism of total salvianolic acids against myocardial ischemia-reperfusion injury based on network pharmacology, molecular docking, and experimental study |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 6 | PM | 38283744 | 📋 | Salvianolic acids and its potential for cardio-protection against myocardial ischemic reperfusion injury in diabetes |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 5 | PM | 37241859 | 📋 | Salvianolic Acid B Inhibits Ferroptosis and Apoptosis during Myocardial Ischemia/Reperfusion Injury via Decreasing the Ubiquitin-Proteasome Degradation of GPX4 and the ROS-JNK/MAPK Pathways |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 3 | PM | 36450557 | 📋 | Salvianolic Acid B Protects Cardiomyocytes from Ischemia/Reperfusion Injury by Mediating circTRRAP/miR-214-3p/SOX6 Axis |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 2 | PM | 35968584 | 📋 | Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathway |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 1 | PM | 28852731 | 📋 | SALVIANOLIC ACID B ALLEVIATING MYOCARDIUM INJURY IN ISCHEMIA REPERFUSION RATS |
| Salvianolic Acid | Myocardial Ischemia-Reperfusion | 4 | PM | 21903157 | 📋 | Proteomic studies on protective effects of salvianolic acids, notoginsengnosides and combination of salvianolic acids and notoginsengnosides against cardiac ischemic-reperfusion injury |
| Salvianolic Acid | Peripheral Arterial Disease | 1 | PM | 35656466 | 📋 | Salvianolic Acid B Alleviates Limb Ischemia in Mice via Promoting SIRT1/PI3K/AKT Pathway-Mediated M2 Macrophage Polarization |
| Salvianolic Acid | Platelet Aggregation | 1 | PM | 33847919 | 📋 | Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway |
| Salvianolic Acid | Renal Ischemia-Reperfusion | 2 | PM | 29384417 | 📋 | Salvianolic acid A ameliorates renal ischemia/reperfusion injury by activating Akt/mTOR/4EBP1 signaling pathway |
| Salvianolic Acid | Renal Ischemia-Reperfusion | 1 | PM | 28513773 | 📋 | Attenuation of renal ischemic reperfusion injury by salvianolic acid B via suppressing oxidative stress and inflammation through PI3K/Akt signaling pathway |
| Salvianolic Acid | Subarachnoid Hemorrhage | 2 | PM | 37564636 | 📋 | Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage |
| Salvianolic Acid | Subarachnoid Hemorrhage | 1 | PM | 29312516 | 📋 | Salvianolic acid A attenuates early brain injury after subarachnoid hemorrhage in rats by regulating ERK/P38/Nrf2 signaling |
| Salvianolic Acid | Thrombosis | 1 | PM | 33847919 | 📋 | Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway |
| Salvianolic Acid | Vascular Disorders | 1 | PM | 37005801 | 📋 | [Protective mechanism of salvianolic acid B on blood vessels] |
| Salvianolic Acid | Vasodilation | 1 | PM | 35700852 | 📋 | Salvianolic acid A from Danhong Injection induces vasorelaxation by Regulating L-type calcium channel in isolated mouse arteries |
