| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Punicalagin | Atherosclerosis | 6 | PM | 37239823 | 📋 | The Role of Punicalagin and Its Metabolites in Atherosclerosis and Risk Factors Associated with the Disease |
| Punicalagin | Atherosclerosis | 5 | PM | 35678674 | 📋 | Punicalagin Targets Atherosclerosis: Gene Expression Profiling of THP-1 Macrophages Treated with Punicalagin and Molecular Docking |
| Punicalagin | Atherosclerosis | 4 | PM | 35565844 | 📋 | Oral Supplement Containing Hydroxytyrosol and Punicalagin Improves Dyslipidemia in an Adult Population without Co-Adjuvant Treatment: A Randomized, Double-Blind, Controlled and Crossover Trial |
| Punicalagin | Atherosclerosis | 3 | PM | 34262908 | 📋 | Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5 |
| Punicalagin | Atherosclerosis | 1 | PM | 33171640 | 📋 | Punicalagin Regulates Key Processes Associated with Atherosclerosis in THP-1 Cellular Model |
| Punicalagin | Atherosclerosis | 2 | PM | 30884808 | 📋 | Supplementation with Hydroxytyrosol and Punicalagin Improves Early Atherosclerosis Markers Involved in the Asymptomatic Phase of Atherosclerosis in the Adult Population: A Randomized, Placebo-Controlled, Crossover Trial |
| Punicalagin | Atherosclerosis | 7 | PM | 23141585 | 📋 | Pomegranate phytosterol (β-sitosterol) and polyphenolic antioxidant (punicalagin) addition to statin, significantly protected against macrophage foam cells formation |
| Punicalagin | Cardiotoxicity | 1 | PM | 31015369 | 📋 | Punicalagin protects H9c2 cardiomyocytes from doxorubicin-induced toxicity through activation of Nrf2/HO-1 signaling |
| Punicalagin | Cerebral Ischemia-Reperfusion | 2 | PM | 25555468 | 📋 | Punicalagin attenuated cerebral ischemia-reperfusion insult via inhibition of proinflammatory cytokines, up-regulation of Bcl-2, down-regulation of Bax, and caspase-3 |
| Punicalagin | Cerebral Ischemia-Reperfusion | 1 | PM | 25282190 | 📋 | Neuroprotective effect of punicalagin against cerebral ischemia reperfusion-induced oxidative brain injury in rats |
| Punicalagin | Diabetic Cardiomyopathy | 1 | PM | 33906428 | 📋 | Punicalagin protects against diabetic cardiomyopathy by promoting Opa1-mediated mitochondrial fusion via regulating PTP1B-Stat3 pathway |
| Punicalagin | Endothelial Dysfunction | 3 | PM | 34867335 | 📋 | Inhibitory Effect of Punicalagin on Inflammatory and Angiogenic Activation of Human Umbilical Vein Endothelial Cells |
| Punicalagin | Endothelial Dysfunction | 2 | PM | 34262908 | 📋 | Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5 |
| Punicalagin | Endothelial Dysfunction | 1 | PM | 30884808 | 📋 | Supplementation with Hydroxytyrosol and Punicalagin Improves Early Atherosclerosis Markers Involved in the Asymptomatic Phase of Atherosclerosis in the Adult Population: A Randomized, Placebo-Controlled, Crossover Trial |
| Punicalagin | Endothelial Dysfunction | 4 | PM | 30878647 | 📋 | Punicalagin attenuates endothelial dysfunction by activating FoxO1, a pivotal regulating switch of mitochondrial biogenesis |
| Punicalagin | Endothelial Dysfunction | 5 | PM | 27222062 | 📋 | Punicalagin Prevents Hypoxic Pulmonary Hypertension via Anti-Oxidant Effects in Rats |
| Punicalagin | Gestational Hypertension | 1 | PM | 29962855 | 📋 | Supplementing punicalagin reduces oxidative stress markers and restores angiogenic balance in a rat model of pregnancy-induced hypertension |
| Punicalagin | Hypertension | 1 | PM | 30884808 | 📋 | Supplementation with Hydroxytyrosol and Punicalagin Improves Early Atherosclerosis Markers Involved in the Asymptomatic Phase of Atherosclerosis in the Adult Population: A Randomized, Placebo-Controlled, Crossover Trial |
| Punicalagin | Myocardial Infarction | 3 | PM | 38736260 | 📋 | Punicalagin attenuates isoproterenol-induced myocardial infarction through nuclear factor erythroid 2-related factor 2/silent information regulator transcript-1-mediated inhibition of inflammation and cardiac stress markers in experimental animal models |
| Punicalagin | Myocardial Infarction | 2 | PM | 37806379 | 📋 | Punicalagin attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats: Biochemical, immunohistochemical, and in silico molecular docking studies |
| Punicalagin | Myocardial Infarction | 1 | PM | 37357417 | 📋 | Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway |
| Punicalagin | Myocardial Ischemia-Reperfusion | 1 | PM | 31063767 | 📋 | Protection of the myocardium against ischemia/reperfusion injury by punicalagin through an SIRT1-NRF-2-HO-1-dependent mechanism |
| Punicalagin | Myocardial Ischemia-Reperfusion | 2 | PM | 28081629 | 📋 | Punicalagin Pretreatment Attenuates Myocardial Ischemia-Reperfusion Injury via Activation of AMPK |
| Punicalagin | Prehypertension | 1 | PM | 30884808 | 📋 | Supplementation with Hydroxytyrosol and Punicalagin Improves Early Atherosclerosis Markers Involved in the Asymptomatic Phase of Atherosclerosis in the Adult Population: A Randomized, Placebo-Controlled, Crossover Trial |
