| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Ginseng | Aging Heart | 3 | PM | 37797916 | 📋 | Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway |
| Ginseng | Aging Heart | 2 | PM | 29376267 | 📋 | [Effect of saponins extracted from Panax japonicus on inhibiting cardiomyocyte apoptosis by AMPK/Sirt1/NF-κB signaling pathway in aging rats] |
| Ginseng | Aging Heart | 1 | PM | 29130614 | 📋 | Panax notoginseng saponins attenuate cardiomyocyte apoptosis through mitochondrial pathway in natural aging rats |
| Ginseng | Anemia | 1 | PM | 37385213 | 📋 | Homotherapy for heteropathy of Alzheimer's disease and anemia through reducing the expression of toll-like receptor and TNF by steamed Panax notoginseng |
| Ginseng | Anemia | 2 | PM | 24837302 | 📋 | The haematopoietic effect of Panax japonicus on blood deficiency model mice |
| Ginseng | Arterial Restenosis | 1 | PM | 37817527 | 📋 | Integrating Network Pharmacology and Experimental Verification to Explore the Targets and Mechanism for Panax Notoginseng Saponins against Coronary In-stent Restenosis |
| Ginseng | Arterial Stiffness | 1 | PM | 23973636 | 📋 | Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant hypertension |
| Ginseng | Atherosclerosis | 7 | PM | 38798151 | 📋 | Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation |
| Ginseng | Atherosclerosis | 6 | PM | 38355288 | 📋 | Ginsenosides retard atherogenesis via remodelling host-microbiome metabolic homeostasis |
| Ginseng | Atherosclerosis | 4 | PM | 36148321 | 📋 | Guanmaitong Granule Attenuates Atherosclerosis by Inhibiting Inflammatory Immune Response in ApoE -/- Mice Fed High-Fat Diet |
| Ginseng | Atherosclerosis | 3 | PM | 35088656 | 📋 | Protective Effect of Panax Notoginseng Saponins on Apolipoprotein-E-deficient Atherosclerosis-prone mice |
| Ginseng | Atherosclerosis | 2 | PM | 35058727 | 📋 | Panax ginseng: Inflammation, platelet aggregation, thrombus formation, and atherosclerosis crosstalk |
| Ginseng | Atherosclerosis | 1 | PM | 34202864 | 📋 | Effect of Korean Red Ginseng on Plasma Ceramide Levels in Postmenopausal Women with Hypercholesterolemia: A Pilot Randomized Controlled Trial |
| Ginseng | Atherosclerosis | 5 | PM | 24130384 | 📋 | Panaxquin quefolium diolsaponins dose-dependently inhibits the proliferation of vascular smooth muscle cells by downregulating proto-oncogene expression |
| Ginseng | Blood-Brain Barrier Permeability | 2 | PM | 34025136 | 📋 | Rg3-enriched Korean Red Ginseng extract inhibits blood-brain barrier disruption in an animal model of multiple sclerosis by modulating expression of NADPH oxidase 2 and 4 |
| Ginseng | Blood-Brain Barrier Permeability | 1 | PM | 32784852 | 📋 | Ginseng Extracts, GS-KG9 and GS-E3D, Prevent Blood-Brain Barrier Disruption and Thereby Inhibit Apoptotic Cell Death of Hippocampal Neurons in Streptozotocin-Induced Diabetic Rats |
| Ginseng | Cardiac Hypertrophy | 1 | PM | 33091308 | 📋 | Inhibition of angiotensin II-induced hypertrophy and cardiac dysfunction by North American ginseng (Panax quinquefolius) |
| Ginseng | Cardiac Hypertrophy | 4 | PM | 27797280 | 📋 | North American ginseng (Panax quinquefolius) suppresses β-adrenergic-dependent signalling, hypertrophy, and cardiac dysfunction |
| Ginseng | Cardiac Hypertrophy | 3 | PM | 22576957 | 📋 | Ginseng reverses established cardiomyocyte hypertrophy and postmyocardial infarction-induced hypertrophy and heart failure |
| Ginseng | Cardiac Hypertrophy | 2 | PM | 21875949 | 📋 | Ginseng (Panax quinquefolius) attenuates leptin-induced cardiac hypertrophy through inhibition of p115Rho guanine nucleotide exchange factor-RhoA/Rho-associated, coiled-coil containing protein kinase-dependent mitogen-activated protein kinase pathway activation |
| Ginseng | Cardiotoxicity | 6 | PM | 38074843 | 📋 | Red Ginseng Is a Therapeutic Candidate for Chronic Doxorubicin-Induced Cardiomyopathy in Mice |
| Ginseng | Cardiotoxicity | 4 | PM | 36529443 | 📋 | Systematic analysis of the material basis and mechanism of total saponins of mountain cultivated ginseng against doxorubicin-induced cardiotoxicity based on integrating network pharmacology and in vivo substance profiling |
| Ginseng | Cardiotoxicity | 3 | PM | 35975564 | 📋 | Protective effects of Panax ginseng against doxorubicin-induced cardiac toxicity in patients with non-metastatic breast cancer: A randomized, double-blind, placebo-controlled clinical trial |
| Ginseng | Cardiotoxicity | 2 | PM | 35814241 | 📋 | Combination of Panax ginseng C. A. Mey and Febuxostat Boasted Cardioprotective Effects Against Doxorubicin-Induced Acute Cardiotoxicity in Rats |
| Ginseng | Cardiotoxicity | 1 | PM | 34617939 | 📋 | Inhibitory effects of Panax ginseng glycoproteins in models of doxorubicin-induced cardiac toxicity in vivo and in vitro |
| Ginseng | Cardiotoxicity | 5 | PM | 31480577 | 📋 | Supplementation of Saponins from Leaves of Panax quinquefolius Mitigates Cisplatin-Evoked Cardiotoxicity via Inhibiting Oxidative Stress-Associated Inflammation and Apoptosis in Mice |
| Ginseng | Cardiovascular Disease | 9 | PM | 38465214 | 📋 | Ginseng and ginsenosides on cardiovascular and pulmonary diseases; Pharmacological potentials for the coronavirus (COVID-19) |
| Ginseng | Cardiovascular Disease | 6 | PM | 36532771 | 📋 | Functional compounds of ginseng and ginseng-containing medicine for treating cardiovascular diseases |
| Ginseng | Cardiovascular Disease | 5 | PM | 36120313 | 📋 | Investigation of the pharmacological effect and mechanism of mountain-cultivated ginseng and garden ginseng in cardiovascular diseases based on network pharmacology and zebrafish experiments |
| Ginseng | Cardiovascular Disease | 4 | PM | 35058725 | 📋 | Effects of Panax ginseng and ginsenosides on oxidative stress and cardiovascular diseases: pharmacological and therapeutic roles |
| Ginseng | Cardiovascular Disease | 3 | PM | 34681234 | 📋 | Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics |
| Ginseng | Cardiovascular Disease | 2 | PM | 33995000 | 📋 | Comparative Analysis of Compatibility Influence on Invigorating Blood Circulation for Combined Use of Panax Notoginseng Saponins and Aspirin Using Metabolomics Approach |
| Ginseng | Cardiovascular Disease | 1 | PM | 33762943 | 📋 | Inhibition of Autophagy Prevents Panax Notoginseng Saponins (PNS) Protection on Cardiac Myocytes Against Endoplasmic Reticulum (ER) Stress-Induced Mitochondrial Injury, Ca 2+ Homeostasis and Associated Apoptosis |
| Ginseng | Cardiovascular Disease | 8 | PM | 29983607 | 📋 | Pharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases |
| Ginseng | Cardiovascular Disease | 7 | PM | 24223639 | 📋 | Computational pharmacological comparison of Salvia miltiorrhiza and Panax notoginseng used in the therapy of cardiovascular diseases |
| Ginseng | Cerebral Ischemia | 4 | PM | 38621909 | 📋 | [Mechanism of astragaloside Ⅳ combined with Panax notoginseng saponins in regulating angiogenesis to treat cerebral ischemia based on network pharmacology and experimental verification] |
| Ginseng | Cerebral Ischemia | 2 | PM | 35968235 | 📋 | Pharmacological Effect of Panax notoginseng Saponins on Cerebral Ischemia in Animal Models |
| Ginseng | Cerebral Ischemia | 1 | PM | 32726010 | 📋 | [Research progress on saponins in Panax notoginseng and their molecular mechanism of anti-cerebral ischemia] |
| Ginseng | Cerebral Ischemia | 3 | PM | 24348784 | 📋 | Protective effect of Panax quinquefolium 20(S)-protopanaxadiol saponins, isolated from Pana quinquefolium, on permanent focal cerebral ischemic injury in rats |
| Ginseng | Cerebral Ischemia-Reperfusion | 13 | PM | 38699996 | 📋 | Panax notoginseng Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia-Reperfusion |
| Ginseng | Cerebral Ischemia-Reperfusion | 9 | PM | 37218204 | 📋 | Total saponins of Panax notoginseng modulate the astrocyte inflammatory signaling pathway and attenuate inflammatory injury induced by oxygen-glucose deprivation/reperfusion injury in rat brain microvascular endothelial cells |
| Ginseng | Cerebral Ischemia-Reperfusion | 8 | PM | 37185938 | 📋 | Effects of borneol combined with astragaloside IV and Panax notoginseng saponins regulation of microglia polarization to promote neurogenesis after cerebral ischaemia |
| Ginseng | Cerebral Ischemia-Reperfusion | 7 | PM | 36952592 | 📋 | The combination of astragaloside IV and Panax notoginseng saponins attenuates cerebral ischaemia-reperfusion injury in rats through ferroptosis and inflammation inhibition via activating Nrf2 |
| Ginseng | Cerebral Ischemia-Reperfusion | 6 | PM | 36472098 | 📋 | Panax notoginseng Saponins Attenuate Cerebral Ischemia-Reperfusion Injury via Mitophagy-Induced Inhibition of NLRP3 Inflammasome in Rats |
| Ginseng | Cerebral Ischemia-Reperfusion | 5 | PM | 35818419 | 📋 | Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice |
| Ginseng | Cerebral Ischemia-Reperfusion | 4 | PM | 35136538 | 📋 | Clinical Observation of Salvianolic Acid Combined with Panax Notoginseng Saponins Combined with Basic Nursing Intervention on Cerebral Ischemia-Reperfusion Injury in Rats |
| Ginseng | Cerebral Ischemia-Reperfusion | 3 | PM | 34581940 | 📋 | Total Saponins of Panax notoginseng Activate Akt/mTOR Pathway and Exhibit Neuroprotection in vitro and in vivo against Ischemic Damage |
| Ginseng | Cerebral Ischemia-Reperfusion | 2 | PM | 34500302 | 📋 | Proteomics and transcriptome reveal the key transcription factors mediating the protection of Panax notoginseng saponins (PNS) against cerebral ischemia/reperfusion injury |
| Ginseng | Cerebral Ischemia-Reperfusion | 1 | PM | 33643030 | 📋 | Effect of Panax notoginseng Saponins on Focal Cerebral Ischemia-Reperfusion in Rat Models: A Meta-Analysis |
| Ginseng | Cerebral Ischemia-Reperfusion | 11 | PM | 29061584 | 📋 | Low Cerebral Exposure Cannot Hinder the Neuroprotective Effects of Panax Notoginsenosides |
| Ginseng | Cerebral Ischemia-Reperfusion | 10 | PM | 24189392 | 📋 | Neuroprotective effect of Panax notoginseng plysaccharides against focal cerebral ischemia reperfusion injury in rats |
| Ginseng | Cerebral Ischemia-Reperfusion | 12 | PM | 20456843 | 📋 | [Effects of astragaloside and Panax notoginseng saponins combination on oxidative stress of cerebral ischemic reperfusion injury in mice] |
| Ginseng | Coronary Artery Disease | 3 | PM | 37854713 | 📋 | Therapeutic mechanisms of ginseng in coronary heart disease |
| Ginseng | Coronary Artery Disease | 2 | PM | 35784716 | 📋 | Panax notoginseng Saponins Alleviate Coronary Artery Disease Through Hypermethylation of the miR-194-MAPK Pathway |
| Ginseng | Coronary Artery Disease | 4 | PM | 33420585 | 📋 | Mechanism of 'Invigorating Qi and Promoting Blood Circulation' Drug Pair Ginseng-Danshen on Treatment of Ischemic Heart Disease Based on Network Pharmacology |
| Ginseng | Coronary Artery Disease | 1 | PM | 32446979 | 📋 | Xinyue Capsule in Patients With Stable Coronary Artery Disease After Percutaneous Coronary Intervention: A Multicenter, Randomized, Placebo-Controlled Trial |
| Ginseng | Deep Vein Thrombosis | 1 | PM | 35829956 | 📋 | Prevention of Deep Vein Thrombosis by Panax Notoginseng Saponins Combined with Low-Molecular-Weight Heparin in Surgical Patients |
| Ginseng | Diabetic Cardiomyopathy | 5 | PM | 37777023 | 📋 | Panax Quinquefolium Saponins enhances angiogenesis in rats with diabetes and myocardial infarction |
| Ginseng | Diabetic Cardiomyopathy | 3 | PM | 35401934 | 📋 | Traditional Chinese Medicine Ginseng Dingzhi Decoction Ameliorates Myocardial Fibrosis and High Glucose-Induced Cardiomyocyte Injury by Regulating Intestinal Flora and Mitochondrial Dysfunction |
| Ginseng | Diabetic Cardiomyopathy | 2 | PM | 35112884 | 📋 | Panax notoginseng Saponin Protects Against Diabetic Cardiomyopathy Through Lipid Metabolism Modulation |
| Ginseng | Diabetic Cardiomyopathy | 1 | PM | 34025138 | 📋 | Effect of Korean Red Ginseng through comparative analysis of cardiac gene expression in db/db mice |
| Ginseng | Diabetic Cardiomyopathy | 4 | PM | 22566158 | 📋 | Preventive effects of North American ginseng (Panax quinquefolius) on diabetic retinopathy and cardiomyopathy |
| Ginseng | Endocarditis | 1 | PM | 37333474 | 📋 | Effect of hydro-alcoholic extract of Panax ginseng and Ampicillin treatment in an animal model of Listeria monocytogenes-induced endocarditis |
| Ginseng | Endothelial Dysfunction | 3 | PM | 34951248 | 📋 | [Mechanism of extract of Ginseng Radix et Rhizoma, Notoginseng Radix et Rhizoma and Chuanxiong Rhizoma on SIRT1 autophagy pathway of endothelial cell senescence induced by hydrogen peroxide] |
| Ginseng | Endothelial Dysfunction | 2 | PM | 34527173 | 📋 | Panax Notoginseng Protects against Diabetes-Associated Endothelial Dysfunction: Comparison between Ethanolic Extract and Total Saponin |
| Ginseng | Endothelial Dysfunction | 1 | PM | 33841015 | 📋 | Korean Red ginseng prevents endothelial senescence by downregulating the HO-1/NF-κB/miRNA-155-5p/eNOS pathway |
| Ginseng | Endothelial Dysfunction | 4 | PM | 24233159 | 📋 | Korean Red Ginseng protects endothelial cells from serum-deprived apoptosis by regulating Bcl-2 family protein dynamics and caspase S-nitrosylation |
| Ginseng | Endothelial Dysfunction | 6 | PM | 23956765 | 📋 | Panax Quinquefolius Saponin of Stem and Leaf Attenuates Intermittent High Glucose-Induced Oxidative Stress Injury in Cultured Human Umbilical Vein Endothelial Cells via PI3K/Akt/GSK-3 β Pathway |
| Ginseng | Endothelial Dysfunction | 5 | PM | 22610957 | 📋 | Influence of high blood glucose fluctuation on endothelial function of type 2 diabetes mellitus rats and effects of Panax Quinquefolius Saponin of stem and leaf |
| Ginseng | Endothelial Injury | 2 | PM | 36090679 | 📋 | DK-MGAR101, an extract of adventitious roots of mountain ginseng, improves blood circulation by inhibiting endothelial cell injury, platelet aggregation, and thrombus formation |
| Ginseng | Endothelial Injury | 1 | PM | 32506850 | 📋 | "Effects of Extracts From Renshen (Radix Ginseng), Sanqi (Radix Notoginseng), and Chuanxiong (Rhizoma Chuanxiong) on F-actin in Senescent Microvascular Endothelial Cells" |
| Ginseng | Endothelial Injury | 3 | PM | 21840692 | 📋 | American ginseng (Panax quinquefolius) prevents glucose-induced oxidative stress and associated endothelial abnormalities |
| Ginseng | Heart Disease | 1 | PM | 35068945 | 📋 | Possibility as role of ginseng and ginsenosides on inhibiting the heart disease of COVID-19: A systematic review |
| Ginseng | Heart Failure | 5 | PM | 37742504 | 📋 | Anti-heart failure mechanism of saponin extract of black ginseng based on metabolomics |
| Ginseng | Heart Failure | 2 | PM | 33472092 | 📋 | Exploring the Protective Effects of PNS on Acute Myocardial Ischaemia-induced Heart Failure by Transcriptome Analysis |
| Ginseng | Heart Failure | 4 | PM | 27797280 | 📋 | North American ginseng (Panax quinquefolius) suppresses β-adrenergic-dependent signalling, hypertrophy, and cardiac dysfunction |
| Ginseng | Heart Failure | 3 | PM | 22576957 | 📋 | Ginseng reverses established cardiomyocyte hypertrophy and postmyocardial infarction-induced hypertrophy and heart failure |
| Ginseng | Heart Failure | 1 | PM | 19445159 | 📋 | [Effects of Ginseng Total Saponins With Berberine on Plasma Brain Natriuretic Peptide and Ca2+ Concentration in Experimental Rats With Chronic Congestive Heart Failure] |
| Ginseng | Hepatic Ischemia-Reperfusion | 1 | PM | 34858181 | 📋 | The Protective Effect of Panax notoginseng Mixture on Hepatic Ischemia/Reperfusion Injury in Mice via Regulating NR3C2, SRC, and GAPDH |
| Ginseng | Hypertension | 1 | PM | 35509826 | 📋 | Effects of Panax ginseng on hyperglycemia, hypertension, and hyperlipidemia: A systematic review and meta-analysis |
| Ginseng | Hypertension | 4 | PM | 32147072 | 📋 | Vascular effects of combined enriched Korean Red ginseng (Panax Ginseng) and American ginseng (Panax Quinquefolius) administration in individuals with hypertension and type 2 diabetes: A randomized controlled trial |
| Ginseng | Hypertension | 3 | PM | 29478187 | 📋 | Efficacy and safety of American ginseng (Panax quinquefolius L.) extract on glycemic control and cardiovascular risk factors in individuals with type 2 diabetes: a double-blind, randomized, cross-over clinical trial |
| Ginseng | Hypertension | 2 | PM | 23973636 | 📋 | Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant hypertension |
| Ginseng | Ischemic Stroke | 18 | PM | 37908976 | 📋 | Efficacy and safety of Panax notoginseng saponins (Xuesaitong) for patients with acute ischemic stroke: a systematic review and meta-analysis of randomized controlled trials |
| Ginseng | Ischemic Stroke | 17 | PM | 37338907 | 📋 | Efficacy and Safety of Panax notoginseng Saponins in the Treatment of Adults With Ischemic Stroke in China: A Randomized Clinical Trial |
| Ginseng | Ischemic Stroke | 16 | PM | 36394713 | 📋 | Components of Salvia miltiorrhiza and Panax notoginseng Protect Pericytes Against OGD/R-Induced Injury via Regulating the PI3K/AKT/mTOR and JNK/ERK/P38 Signaling Pathways |
| Ginseng | Ischemic Stroke | 15 | PM | 36271540 | 📋 | Panax notoginseng saponins alleviates inflammation induced by microglial activation and protects against ischemic brain injury via inhibiting HIF-1α/PKM2/STAT3 signaling |
| Ginseng | Ischemic Stroke | 14 | PM | 36091745 | 📋 | Combination of panax ginseng and ginkgo biloba extracts attenuate cerebral ischemia injury with modulation of NLRP3 inflammasome and CAMK4/CREB pathway |
| Ginseng | Ischemic Stroke | 13 | PM | 35873557 | 📋 | A Review of Neuroprotective Effects and Mechanisms of Ginsenosides From Panax Ginseng in Treating Ischemic Stroke |
| Ginseng | Ischemic Stroke | 12 | PM | 35770087 | 📋 | Panax notoginseng Saponins Stimulates Neurogenesis and Neurological Restoration After Microsphere-Induced Cerebral Embolism in Rats Partially Via mTOR Signaling |
| Ginseng | Ischemic Stroke | 11 | PM | 35509825 | 📋 | Neuroprotective effects of Korean White ginseng and Red ginseng in an ischemic stroke mouse model |
| Ginseng | Ischemic Stroke | 8 | PM | 35056059 | 📋 | Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway |
| Ginseng | Ischemic Stroke | 10 | PM | 34733959 | 📋 | Safflower yellow pigment and Sanqi Panax notoginseng in the treatment of acute cerebral infarction: a systematic review, meta-analysis, and cost-effectiveness analysis |
| Ginseng | Ischemic Stroke | 6 | PM | 34467686 | 📋 | [Overview of systematic reviews of Panax notoginseng saponins in treatment of acute cerebral infarction] |
| Ginseng | Ischemic Stroke | 5 | PM | 34462642 | 📋 | The RIG-I Signal Pathway Mediated Panax notoginseng Saponin Anti-Inflammatory Effect in Ischemia Stroke |
| Ginseng | Ischemic Stroke | 4 | PM | 34335808 | 📋 | Systematic Review and Meta-Analysis on Randomized Controlled Trials on Efficacy and Safety of Panax Notoginseng Saponins in Treatment of Acute Ischemic Stroke |
| Ginseng | Ischemic Stroke | 7 | PM | 33643030 | 📋 | Effect of Panax notoginseng Saponins on Focal Cerebral Ischemia-Reperfusion in Rat Models: A Meta-Analysis |
| Ginseng | Ischemic Stroke | 3 | PM | 33468191 | 📋 | Anti-platelet aggregation of Panax notoginseng triol saponins by regulating GP1BA for ischemic stroke therapy |
| Ginseng | Ischemic Stroke | 1 | PM | 33173991 | 📋 | Using mRNA deep sequencing to analyze differentially expressed genes during Panax notoginseng saponin treatment of ischemic stroke |
| Ginseng | Ischemic Stroke | 9 | PM | 33149812 | 📋 | Notoginseng Leaf Triterpenes Ameliorates OGD/R-Induced Neuronal Injury via SIRT1/2/3-Foxo3a-MnSOD/PGC-1 α Signaling Pathways Mediated by the NAMPT-NAD Pathway |
| Ginseng | Ischemic Stroke | 2 | PM | 32531700 | 📋 | The Combination of Panax Ginseng and Angelica Sinensis Alleviates Ischemia Brain Injury by Suppressing NLRP3 Inflammasome Activation and Microglial Pyroptosis |
| Ginseng | Middle Cerebral Artery Occlusion | 2 | PM | 33617967 | 📋 | Xuesaitong exerts long-term neuroprotection for stroke recovery by inhibiting the ROCKII pathway, in vitro and in vivo |
| Ginseng | Myocardial Fibrosis | 3 | PM | 35401934 | 📋 | Traditional Chinese Medicine Ginseng Dingzhi Decoction Ameliorates Myocardial Fibrosis and High Glucose-Induced Cardiomyocyte Injury by Regulating Intestinal Flora and Mitochondrial Dysfunction |
| Ginseng | Myocardial Fibrosis | 2 | PM | 35372585 | 📋 | Using Network Pharmacology to Explore the Mechanism of Panax notoginseng in the Treatment of Myocardial Fibrosis |
| Ginseng | Myocardial Fibrosis | 1 | PM | 33292321 | 📋 | Panax ginseng C. A. Meyer as a potential therapeutic agent for organ fibrosis disease |
| Ginseng | Myocardial Infarction | 12 | PM | 37954484 | 📋 | Panax quinquefolium L. and Salvia miltiorrhiza Bunge. Enhances Angiogenesis by Regulating the miR-155-5p/HIF-1α/VEGF Axis in Acute Myocardial Infarction |
| Ginseng | Myocardial Infarction | 11 | PM | 37777023 | 📋 | Panax Quinquefolium Saponins enhances angiogenesis in rats with diabetes and myocardial infarction |
| Ginseng | Myocardial Infarction | 5 | PM | 36557992 | 📋 | The Synergistic Mechanism of Total Saponins and Flavonoids in Notoginseng-Safflower against Myocardial Infarction Using a Comprehensive Metabolomics Strategy |
| Ginseng | Myocardial Infarction | 4 | PM | 33996504 | 📋 | The cardio and renoprotective role of ginseng against epinephrine-induced myocardial infarction in rats: Involvement of angiotensin II type 1 receptor/protein kinase C |
| Ginseng | Myocardial Infarction | 3 | PM | 33485065 | 📋 | Cardioprotection of Panax Notoginseng saponins against acute myocardial infarction and heart failure through inducing autophagy |
| Ginseng | Myocardial Infarction | 2 | PM | 33259022 | 📋 | Panax Notoginseng Saponins Inhibits Ventricular Remodeling after Myocardial Infarction in Rats Through Regulating ATF3/MAP2K3/p38 MAPK and NF κ B Pathway |
| Ginseng | Myocardial Infarction | 1 | PM | 32976970 | 📋 | Autophagy as a novel insight into mechanism of Danqi pill against post-acute myocardial infarction heart failure |
| Ginseng | Myocardial Infarction | 10 | PM | 29584740 | 📋 | Panax quinquefolius saponins combined with dual antiplatelet drug therapy alleviate gastric mucosal injury and thrombogenesis through the COX/PG pathway in a rat model of acute myocardial infarction |
| Ginseng | Myocardial Infarction | 6 | PM | 26199551 | 📋 | Ginseng total saponin attenuates myocardial injury via anti-oxidative and anti-inflammatory properties |
| Ginseng | Myocardial Infarction | 8 | PM | 25154304 | 📋 | Protective effect of saponins extract from Panax japonicus on myocardial infarction: involvement of NF-κB, Sirt1 and mitogen-activated protein kinase signalling pathways and inhibition of inflammation |
| Ginseng | Myocardial Infarction | 9 | PM | 23864891 | 📋 | Effective Components of Panax quinquefolius and Corydalis tuber Protect Myocardium through Attenuating Oxidative Stress and Endoplasmic Reticulum Stress |
| Ginseng | Myocardial Infarction | 7 | PM | 23856922 | 📋 | Panax quinquefolium saponin attenuates ventricular remodeling after acute myocardial infarction by inhibiting chop-mediated apoptosis |
| Ginseng | Myocardial Injury | 3 | PM | 34604348 | 📋 | Cardioprotective Effect of Stem-Leaf Saponins From Panax notoginseng on Mice With Sleep Derivation by Inhibiting Abnormal Autophagy Through PI3K/Akt/mTOR Pathway |
| Ginseng | Myocardial Injury | 2 | PM | 33996504 | 📋 | The cardio and renoprotective role of ginseng against epinephrine-induced myocardial infarction in rats: Involvement of angiotensin II type 1 receptor/protein kinase C |
| Ginseng | Myocardial Injury | 1 | PM | 32973948 | 📋 | Panax notoginseng saponins alleviates advanced glycation end product-induced apoptosis by upregulating SIRT1 and antioxidant expression levels in HUVECs |
| Ginseng | Myocardial Ischemia | 11 | PM | 38107394 | 📋 | The purified extract of steamed Panax ginseng protects cardiomyocyte from ischemic injury via caveolin-1 phosphorylation-mediating calcium influx |
| Ginseng | Myocardial Ischemia | 7 | PM | 36153627 | 📋 | Characterization of a novel polysaccharide from red ginseng and its ameliorative effect on oxidative stress injury in myocardial ischemia |
| Ginseng | Myocardial Ischemia | 5 | PM | 34981530 | 📋 | Comprehensive phytochemicals analysis and anti-myocardial ischemia activity of total saponins of American ginseng berry |
| Ginseng | Myocardial Ischemia | 6 | PM | 33472092 | 📋 | Exploring the Protective Effects of PNS on Acute Myocardial Ischaemia-induced Heart Failure by Transcriptome Analysis |
| Ginseng | Myocardial Ischemia | 3 | PM | 33301914 | 📋 | Global Gene Expression Analysis Using RNA-seq Reveals the New Roles of Panax Notoginseng Saponins in Ischemic Cardiomyocytes |
| Ginseng | Myocardial Ischemia | 2 | PM | 32627489 | 📋 | [Screening of Active Anti-Myocardial Ischemia Components of Panax Notoginseng Based on Molecular Docking Technology] |
| Ginseng | Myocardial Ischemia | 1 | PM | 32627464 | 📋 | [Characterization Analysis Technique of Panax Notoginseng Saponin Subcomponents for Prevention and Treatment of Myocardial Ischemia Based on Their Structure and Effect Differences] |
| Ginseng | Myocardial Ischemia | 9 | PM | 23946687 | 📋 | Korean Red Ginseng Induced Cardioprotection against Myocardial Ischemia in Guinea Pig |
| Ginseng | Myocardial Ischemia | 10 | PM | 23213738 | 📋 | [Effects of total saponin from Panax japonicus on acute myocardial ischemia injury induced by ligating coronary artery left anterior descending branch in rats] |
| Ginseng | Myocardial Ischemia | 8 | PM | 22226974 | 📋 | Cardioprotective effects of saponins from Panax japonicus on acute myocardial ischemia against oxidative stress-triggered damage and cardiac cell death in rats |
| Ginseng | Myocardial Ischemia-Reperfusion | 6 | PM | 36108895 | 📋 | Panax ginseng against myocardial ischemia/reperfusion injury: A review of preclinical evidence and potential mechanisms |
| Ginseng | Myocardial Ischemia-Reperfusion | 5 | PM | 36090756 | 📋 | A tRNA-derived fragment of ginseng protects heart against ischemia/reperfusion injury via targeting the lncRNA MIAT/VEGFA pathway |
| Ginseng | Myocardial Ischemia-Reperfusion | 4 | PM | 34354001 | 📋 | Panax notoginseng saponins protect H9c2 cells from hypoxia-reoxygenation injury through FOXO3a/HIF-1α cell signaling pathway |
| Ginseng | Myocardial Ischemia-Reperfusion | 3 | PM | 33628178 | 📋 | Panax quinquefolius L. Saponins Protect Myocardial Ischemia Reperfusion No-Reflow Through Inhibiting the Activation of NLRP3 Inflammasome via TLR4/MyD88/NF-κB Signaling Pathway |
| Ginseng | Myocardial Ischemia-Reperfusion | 2 | PM | 33597866 | 📋 | Saponins in Chinese Herbal Medicine Exerts Protection in Myocardial Ischemia-Reperfusion Injury: Possible Mechanism and Target Analysis |
| Ginseng | Myocardial Ischemia-Reperfusion | 1 | PM | 33134375 | 📋 | ATP-Sensitive Potassium Channels Mediate the Cardioprotective Effect of Panax notoginseng Saponins against Myocardial Ischaemia-Reperfusion Injury and Inflammatory Reaction |
| Ginseng | Myocarditis | 1 | PM | 37206567 | 📋 | A combination of Sophora flavescens alkaloids and Panax quinquefolium saponins attenuates coxsackievirus B3‑induced acute myocarditis in mice via NF‑κB signaling |
| Ginseng | Platelet Aggregation | 3 | PM | 36569332 | 📋 | Panax notoginseng preparation plus aspirin versus aspirin alone on platelet aggregation and coagulation in patients with coronary heart disease or ischemic stroke: A meta-analysis of randomized controlled trials |
| Ginseng | Platelet Aggregation | 6 | PM | 36090679 | 📋 | DK-MGAR101, an extract of adventitious roots of mountain ginseng, improves blood circulation by inhibiting endothelial cell injury, platelet aggregation, and thrombus formation |
| Ginseng | Platelet Aggregation | 8 | PM | 35600768 | 📋 | Comparative antiplatelet and antithrombotic effects of red ginseng and fermented red ginseng extracts |
| Ginseng | Platelet Aggregation | 5 | PM | 35068944 | 📋 | COVID-19 and Panax ginseng: Targeting platelet aggregation, thrombosis and the coagulation pathway |
| Ginseng | Platelet Aggregation | 4 | PM | 35058727 | 📋 | Panax ginseng: Inflammation, platelet aggregation, thrombus formation, and atherosclerosis crosstalk |
| Ginseng | Platelet Aggregation | 7 | PM | 33485065 | 📋 | Cardioprotection of Panax Notoginseng saponins against acute myocardial infarction and heart failure through inducing autophagy |
| Ginseng | Platelet Aggregation | 1 | PM | 33468191 | 📋 | Anti-platelet aggregation of Panax notoginseng triol saponins by regulating GP1BA for ischemic stroke therapy |
| Ginseng | Platelet Aggregation | 2 | PM | 33370633 | 📋 | Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury via modulating arachidonic acid metabolism |
| Ginseng | Platelet Aggregation | 9 | PM | 29174034 | 📋 | Panax notoginseng saponins reduce high-risk factors for thrombosis through peroxisome proliferator-activated receptor -γ pathway |
| Ginseng | Platelet Aggregation | 10 | PM | 24196231 | 📋 | Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis |
| Ginseng | Poor Circulation | 1 | PM | 33995000 | 📋 | Comparative Analysis of Compatibility Influence on Invigorating Blood Circulation for Combined Use of Panax Notoginseng Saponins and Aspirin Using Metabolomics Approach |
| Ginseng | Poor Circulation | 2 | PM | 33420585 | 📋 | Mechanism of 'Invigorating Qi and Promoting Blood Circulation' Drug Pair Ginseng-Danshen on Treatment of Ischemic Heart Disease Based on Network Pharmacology |
| Ginseng | RBC Count Abnormal | 1 | PM | 33719260 | 📋 | [Protective effect of Ginseng Guipi Pill on liver injury in rats with spleen failing to control blood syndrome and its mechanism] |
| Ginseng | Renal Ischemia-Reperfusion | 2 | PM | 37144215 | 📋 | A molecular network-based pharmacological study on the protective effect of Panax notoginseng rhizomes against renal ischemia-reperfusion injury |
| Ginseng | Renal Ischemia-Reperfusion | 1 | PM | 33041791 | 📋 | Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways |
| Ginseng | Sickle-Cell Anemia | 1 | PM | 26444603 | 📋 | Pfaffia paniculata extract improves red blood cell deformability in sickle cell patients |
| Ginseng | Stroke | 2 | PM | 37181679 | 📋 | Evaluation on the Efficacy and Safety of Panax Notoginseng Saponins in the Treatment of Stroke among Elderly People: A Systematic Review and Meta-Analysis of 206 Randomized Controlled Trials |
| Ginseng | Stroke | 1 | PM | 33617967 | 📋 | Xuesaitong exerts long-term neuroprotection for stroke recovery by inhibiting the ROCKII pathway, in vitro and in vivo |
| Ginseng | Stroke | 3 | PM | 33294469 | 📋 | Genes Induced by Panax Notoginseng in a Rodent Model of Ischemia-Reperfusion Injury |
| Ginseng | Thrombosis | 5 | PM | 36090679 | 📋 | DK-MGAR101, an extract of adventitious roots of mountain ginseng, improves blood circulation by inhibiting endothelial cell injury, platelet aggregation, and thrombus formation |
| Ginseng | Thrombosis | 4 | PM | 35600768 | 📋 | Comparative antiplatelet and antithrombotic effects of red ginseng and fermented red ginseng extracts |
| Ginseng | Thrombosis | 3 | PM | 35068944 | 📋 | COVID-19 and Panax ginseng: Targeting platelet aggregation, thrombosis and the coagulation pathway |
| Ginseng | Thrombosis | 2 | PM | 35058727 | 📋 | Panax ginseng: Inflammation, platelet aggregation, thrombus formation, and atherosclerosis crosstalk |
| Ginseng | Thrombosis | 1 | PM | 32322295 | 📋 | Antithrombotic Effect and Action Mechanism of Salvia miltiorrhiza and Panax notoginseng Herbal Pair on the Zebrafish |
| Ginseng | Thrombosis | 8 | PM | 29174034 | 📋 | Panax notoginseng saponins reduce high-risk factors for thrombosis through peroxisome proliferator-activated receptor -γ pathway |
| Ginseng | Thrombosis | 9 | PM | 27401285 | 📋 | Panax quinquefolium saponin combined with dual antiplatelet drugs inhibits platelet adhesion to injured HUVECs via PI3K/AKT and COX pathways |
| Ginseng | Thrombosis | 7 | PM | 24196231 | 📋 | Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis |
| Ginseng | Vascular Disorders | 3 | PM | 35026867 | 📋 | Ginseng in vascular dysfunction: A review of therapeutic potentials and molecular mechanisms |
| Ginseng | Vascular Disorders | 2 | PM | 34527173 | 📋 | Panax Notoginseng Protects against Diabetes-Associated Endothelial Dysfunction: Comparison between Ethanolic Extract and Total Saponin |
| Ginseng | Vascular Disorders | 1 | PM | 33841015 | 📋 | Korean Red ginseng prevents endothelial senescence by downregulating the HO-1/NF-κB/miRNA-155-5p/eNOS pathway |
| Ginseng | Vasculitis | 1 | PM | 35088656 | 📋 | Protective Effect of Panax Notoginseng Saponins on Apolipoprotein-E-deficient Atherosclerosis-prone mice |
| Ginseng | Vasodilation | 1 | PM | 25284751 | 📋 | Efficacy and safety of Korean red ginseng for cold hypersensitivity in the hands and feet: a randomized, double-blind, placebo-controlled trial |
