| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Crocetin | Atherosclerosis | 3 | PM | 34615830 | 📋 | Cardio-protective and Anti-atherosclerosis Effect of Crocetin on Vitamin D3 and HFD-induced Atherosclerosis in Rats |
| Crocetin | Atherosclerosis | 1 | PM | 31667483 | 📋 | The effect of crocetin supplementation on markers of atherogenic risk in patients with coronary artery disease: a pilot, randomized, double-blind, placebo-controlled clinical trial |
| Crocetin | Atherosclerosis | 2 | PM | 29692651 | 📋 | Influence of crocetin on high-cholesterol diet induced atherosclerosis in rats via anti-oxidant activity together with inhibition of inflammatory response and p38 MAPK signaling pathway |
| Crocetin | Cardiac Hypertrophy | 2 | PM | 19413885 | 📋 | Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway |
| Crocetin | Cardiac Hypertrophy | 1 | PM | 16649553 | 📋 | Effects of crocetin on antioxidant enzymatic activities in cardiac hypertrophy induced by norepinephrine in rats |
| Crocetin | Cardiotoxicity | 1 | PM | 34697146 | 📋 | Protective Effects of Crocetin on Arsenic Trioxide-induced Oxidative Stress in Human Umbilical Vein Endothelial Cells |
| Crocetin | Cardiovascular Disease | 3 | PM | 34615830 | 📋 | Cardio-protective and Anti-atherosclerosis Effect of Crocetin on Vitamin D3 and HFD-induced Atherosclerosis in Rats |
| Crocetin | Cardiovascular Disease | 1 | PM | 32879211 | 📋 | Influence of Crocetin, a Natural Carotenoid Dicarboxylic Acid in Saffron, on L-Type Ca 2+ Current, Intracellular Ca 2+ Handling and Contraction of Isolated Rat Cardiomyocytes |
| Crocetin | Diabetic Vasculopathy | 1 | PM | 28528862 | 📋 | Crocetin restores diabetic endothelial progenitor cell dysfunction by enhancing NO bioavailability via regulation of PI3K/AKT-eNOS and ROS pathways |
| Crocetin | Diabetic Vasculopathy | 2 | PM | 28209519 | 📋 | Effect of crocetin on vascular smooth muscle cells migration induced by advanced glycosylation end products |
| Crocetin | Endothelial Dysfunction | 2 | PM | 28528862 | 📋 | Crocetin restores diabetic endothelial progenitor cell dysfunction by enhancing NO bioavailability via regulation of PI3K/AKT-eNOS and ROS pathways |
| Crocetin | Endothelial Dysfunction | 1 | PM | 27889767 | 📋 | Crocetin Inhibits Lipopolysaccharide-Induced Inflammatory Response in Human Umbilical Vein Endothelial Cells |
| Crocetin | Heart Failure | 1 | PM | 38675456 | 📋 | Preventive and Therapeutic Effects of Crocetin in Rats with Heart Failure |
| Crocetin | Hepatic Ischemia-Reperfusion | 1 | PM | 38781791 | 📋 | Crocetin preconditioning attenuates ischemia reperfusion-induced hepatic injury by disrupting Keap1/Nrf2 interaction and activating Nrf2/HO-1 pathway |
| Crocetin | Hypertension | 1 | PM | 25531977 | 📋 | Crocetin, a carotenoid derived from saffron (Crocus sativus L.), improves acetylcholine-induced vascular relaxation in hypertension |
| Crocetin | Ischemia-Reperfusion Injuries | 1 | PM | 35619323 | 📋 | Crocetin suppresses uterine ischemia/reperfusion-induced inflammation and apoptosis through Nrf-2/HO-1 pathway |
| Crocetin | Ischemic Stroke | 3 | PM | 37001492 | 📋 | Crocetin Regulates Functions of Neural Stem Cells to Generate New Neurons for Cerebral Ischemia Recovery |
| Crocetin | Ischemic Stroke | 2 | PM | 36681688 | 📋 | Crocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I |
| Crocetin | Ischemic Stroke | 1 | PM | 35991882 | 📋 | Crocins for Ischemic Stroke: A Review of Current Evidence |
| Crocetin | Myocardial Infarction | 1 | PM | 28651239 | 📋 | Cardiaprotective effect of crocetin by attenuating apoptosis in isoproterenol induced myocardial infarction rat model |
| Crocetin | Myocardial Injury | 1 | PM | 32581829 | 📋 | Crocetin Attenuates Sepsis-Induced Cardiac Dysfunction via Regulation of Inflammatory Response and Mitochondrial Function |
| Crocetin | Myocardial Ischemia | 1 | PM | 31974615 | 📋 | Crocetin alleviates myocardial ischemia/reperfusion injury by regulating inflammation and the unfolded protein response |
| Crocetin | Myocardial Ischemia | 2 | PM | 27285672 | 📋 | Crocetin ester improves myocardial ischemia via Rho/ROCK/NF-κB pathway |
| Crocetin | Myocardial Ischemia-Reperfusion | 1 | PM | 36875162 | 📋 | Crocetin protects cardiomyocytes against hypoxia/reoxygenation injury by attenuating Drp1-mediated mitochondrial fission via PGC-1α |
| Crocetin | Myocarditis | 1 | PM | 34349088 | 📋 | Crocetin Exerts a Cardio-protective Effect on Mice with Coxsackievirus B3-induced Acute Viral Myocarditis |
| Crocetin | Renal Ischemia-Reperfusion | 1 | PM | 32089976 | 📋 | The Carotenoid Compound of Saffron Crocetin Alleviates Effects of Ischemia Reperfusion Injury via a Mechanism Possibly Involving MiR-127 |
| Crocetin | Vasculitis | 1 | PM | 27889767 | 📋 | Crocetin Inhibits Lipopolysaccharide-Induced Inflammatory Response in Human Umbilical Vein Endothelial Cells |
| Crocetin | Vasodilation | 1 | PM | 25531977 | 📋 | Crocetin, a carotenoid derived from saffron (Crocus sativus L.), improves acetylcholine-induced vascular relaxation in hypertension |
