| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Vitamin E | Acute Lymphoblastic Leukemia | 1 | PM | 19960046 | 📋 | Vitamin E and N-acetylcysteine as Antioxidant Adjuvant Therapy in Children With Acute Lymphoblastic Leukemia |
| Vitamin E | Acute Promyelocytic Leukemia | 2 | PM | 32154163 | 📋 | L-Ascorbic Acid and α-Tocopherol Synergistically Triggers Apoptosis Inducing Antileukemic Effects of Arsenic Trioxide via Oxidative Stress in Human Acute Promyelocytic Leukemia Cells |
| Vitamin E | Acute Promyelocytic Leukemia | 1 | PM | 20015448 | 📋 | Vitamin E and Rutin Synergistically Inhibit Expression of Vascular Endothelial Growth Factor Through Down-Regulation of Binding Activity of Activator protein-1 in Human Promyelocytic Leukemia (HL-60) Cells |
| Vitamin E | Breast Cancer | 14 | PM | 37240924 | 📋 | An Update on Tamoxifen and the Chemo-Preventive Potential of Vitamin E in Breast Cancer Management |
| Vitamin E | Breast Cancer | 13 | PM | 37100890 | 📋 | Relationship between food-derived antioxidant vitamin intake and breast cancer risk: a mendelian randomized study |
| Vitamin E | Breast Cancer | 12 | PM | 36657931 | 📋 | Chemopreventive and anti-tumor potential of vitamin E in preclinical breast cancer studies: A systematic review |
| Vitamin E | Breast Cancer | 11 | PM | 35100963 | 📋 | Gamma-tocotrienol Synergistically Promotes the Anti-proliferative and Pro-apoptotic Effects of Etoposide on Breast Cancer Cell Lines |
| Vitamin E | Breast Cancer | 10 | PM | 35092389 | 📋 | Effects of Vitamin E on Doxorubicin Cytotoxicity in Human Breast Cancer Cells in Vitro |
| Vitamin E | Breast Cancer | 9 | PM | 33556581 | 📋 | γ-Tocotrienol reverses multidrug resistance of breast cancer cells through the regulation of the γ-Tocotrienol-NF-κB-P-gp axis |
| Vitamin E | Breast Cancer | 15 | PM | 29435127 | 📋 | α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro |
| Vitamin E | Breast Cancer | 7 | PM | 28972008 | 📋 | Differential Gene Regulation and Tumor-Inhibitory Activities of Alpha-, Delta-, and Gamma-Tocopherols in Estrogen-Mediated Mammary Carcinogenesis |
| Vitamin E | Breast Cancer | 3 | PM | 28096236 | 📋 | Inhibitory Effects of γ- and δ-Tocopherols on Estrogen-Stimulated Breast Cancer In Vitro and In Vivo |
| Vitamin E | Breast Cancer | 8 | PM | 28004315 | 📋 | Bioflavonoid Fisetin Loaded α-Tocopherol-Poly(lactic acid)-Based Polymeric Micelles for Enhanced Anticancer Efficacy in Breast Cancers |
| Vitamin E | Breast Cancer | 4 | PM | 24782330 | 📋 | Tocopherols inhibit oxidative and nitrosative stress in estrogen-induced early mammary hyperplasia in ACI rats |
| Vitamin E | Breast Cancer | 5 | PM | 19771520 | 📋 | Endoplasmic reticulum stress mediates gamma-tocotrienol-induced apoptosis in mammary tumor cells |
| Vitamin E | Breast Cancer | 6 | PM | 19359655 | 📋 | Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1 |
| Vitamin E | Breast Cancer | 1 | PM | 19089916 | 📋 | Telomere length, oxidative damage, antioxidants and breast cancer risk |
| Vitamin E | Breast Cancer | 2 | PM | 15329916 | 📋 | Effect of vitamin B12, folate, and dietary supplements on breast carcinoma chemotherapy--induced mucositis and neutropenia |
| Vitamin E | Cancer | 13 | PM | 37111076 | 📋 | Molecular Mechanism of Tocotrienol-Mediated Anticancer Properties: A Systematic Review of the Involvement of Endoplasmic Reticulum Stress and Unfolded Protein Response |
| Vitamin E | Cancer | 12 | PM | 36978880 | 📋 | Antioxidant and Anti-Tumor Effects of Dietary Vitamins A, C, and E |
| Vitamin E | Cancer | 11 | PM | 35420681 | 📋 | Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1 |
| Vitamin E | Cancer | 10 | PM | 34278890 | 📋 | Role of Vitamin E in Selected Malignant Neoplasms in Women |
| Vitamin E | Cancer | 4 | PM | 30548200 | 📋 | Natural forms of vitamin E and metabolites-regulation of cancer cell death and underlying mechanisms |
| Vitamin E | Cancer | 2 | PM | 29141970 | 📋 | Natural Forms of Vitamin E as Effective Agents for Cancer Prevention and Therapy |
| Vitamin E | Cancer | 5 | PM | 26948691 | 📋 | Tocotrienol and cancer metastasis |
| Vitamin E | Cancer | 6 | PM | 26751721 | 📋 | Tocopherols in cancer: An update |
| Vitamin E | Cancer | 3 | PM | 25662730 | 📋 | α-Tocopherol suppresses antiangiogenic effect of δ-tocotrienol in human umbilical vein endothelial cells |
| Vitamin E | Cancer | 7 | PM | 25304969 | 📋 | α-Tocopherol mediated amelioration of camptothecin-induced free radical damage to avert cardiotoxicities |
| Vitamin E | Cancer | 14 | PM | 23403075 | 📋 | Cancer prevention by tocopherols and tea polyphenols |
| Vitamin E | Cancer | 8 | PM | 21320073 | 📋 | α-Tocopherol attenuates NF-κB activation and pro-inflammatory cytokine IL-6 secretion in cancer-bearing mice |
| Vitamin E | Cancer | 1 | PM | 20587949 | 📋 | Possible Action Mechanism for Curcumin in Pre-Cancerous Lesions Based on Serum and Salivary Markers of Oxidative Stress |
| Vitamin E | Cancer | 9 | PM | 17309809 | 📋 | Do the dietary supplements epigallocatechin gallate or vitamin e cause a radiomodifying response on tumors in vivo? A pilot study with murine breast carcinoma |
| Vitamin E | Cervical Cancer | 3 | PM | 34093795 | 📋 | Vitamin E succinate exerts anti-tumour effects on human cervical cancer cells via the CD47-SIRPɑ pathway both in vivo and in vitro |
| Vitamin E | Cervical Cancer | 2 | PM | 29770585 | 📋 | Exploring the effect of vitamin E in cancer chemotherapy-A biochemical and biophysical insight |
| Vitamin E | Cervical Cancer | 1 | PM | 26337940 | 📋 | Associations between antioxidant vitamins and the risk of invasive cervical cancer in Chinese women: A case-control study |
| Vitamin E | Chronic Myeloid Leukemia | 1 | PM | 32231189 | 📋 | Aberrant Expression of Placental-Like Alkaline Phosphatase in Chronic Myeloid Leukemia Cells in Vitro and Its Modulation by Vitamin E |
| Vitamin E | Cisplatin Toxicity | 5 | PM | 35408581 | 📋 | Baicalein and Αlpha-Tocopherol Inhibit Toll-like Receptor Pathways in Cisplatin-Induced Nephrotoxicity |
| Vitamin E | Cisplatin Toxicity | 4 | PM | 33054896 | 📋 | Effect of Vitamin E on Cisplatin-induced Memory Impairment in Male Rats |
| Vitamin E | Cisplatin Toxicity | 3 | PM | 32767013 | 📋 | The protective efficacy of vitamin E and cod liver oil against cisplatin-induced acute kidney injury in rats |
| Vitamin E | Cisplatin Toxicity | 1 | PM | 27247921 | 📋 | The protective effect of Nigella sativa against cisplatin-induced nephrotoxicity in rats |
| Vitamin E | Cisplatin Toxicity | 2 | PM | 26514460 | 📋 | Protective Role of Selenium and High Dose Vitamin E Against Cisplatin - Induced Nephrotoxicty in Rats |
| Vitamin E | Colon Cancer | 5 | PM | 38019686 | 📋 | Chemopreventive effects of α-tocopherol and its long-chain metabolites α-13'-hydroxy- and α-13'-carboxychromanol in LT97 colon adenoma cells |
| Vitamin E | Colon Cancer | 4 | PM | 36921708 | 📋 | Combining gamma-tocopherol and aspirin synergistically suppresses colitis-associated colon tumorigenesis and modulates the gut microbiota in mice, and inhibits the growth of human colon cancer cells |
| Vitamin E | Colon Cancer | 3 | PM | 33347911 | 📋 | Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice: Tocotrienol and 13'-carboxychromanol modulate gut microbiota |
| Vitamin E | Colon Cancer | 1 | PM | 27175800 | 📋 | δ- and γ-tocopherols inhibit phIP/DSS-induced colon carcinogenesis by protection against early cellular and DNA damages |
| Vitamin E | Colon Cancer | 2 | PM | 19121919 | 📋 | Inhibition of proliferation and induction of apoptosis by gamma-tocotrienol in human colon carcinoma HT-29 cells |
| Vitamin E | Colorectal Cancer | 7 | PM | 37282563 | 📋 | Vitamin E intake and paraoxonase 1 ( PON1) rs662 genetic polymorphism are associated with colorectal cancer risk in a Korean population |
| Vitamin E | Colorectal Cancer | 6 | PM | 36191991 | 📋 | The Complex Composition of Trans-resveratrol, Quercetin, Vitamin E and Selenium Inhibits the Growth of Colorectal Carcinoma |
| Vitamin E | Colorectal Cancer | 5 | PM | 35592289 | 📋 | The association among calorie, macronutrient, and micronutrient intake with colorectal cancer: A case-control study |
| Vitamin E | Colorectal Cancer | 4 | PM | 34803703 | 📋 | Combined Effects of Resveratrol and Vitamin E From Peanut Seeds and Sprouts on Colorectal Cancer Cells |
| Vitamin E | Colorectal Cancer | 1 | PM | 32196510 | 📋 | Natural Agents Inhibit Colon Cancer Cell Proliferation and Alter Microbial Diversity in Mice |
| Vitamin E | Colorectal Cancer | 3 | PM | 28682917 | 📋 | Link between risk of colorectal cancer and serum vitamin E levels: A meta-analysis of case-control studies |
| Vitamin E | Colorectal Cancer | 2 | PM | 25979648 | 📋 | δ-Tocotrienol treatment is more effective against hypoxic tumor cells than normoxic cells: potential implications for cancer therapy |
| Vitamin E | Esophageal Cancer | 4 | PM | 29662196 | 📋 | Tocopherols inhibit esophageal carcinogenesis through attenuating NF-κB activation and CXCR3-mediated inflammation |
| Vitamin E | Esophageal Cancer | 5 | PM | 29221176 | 📋 | Alpha-Tocopherol prevents esophageal squamous cell carcinoma by modulating PPARγ-Akt signaling pathway at the early stage of carcinogenesis |
| Vitamin E | Esophageal Cancer | 3 | PM | 27357907 | 📋 | Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells |
| Vitamin E | Esophageal Cancer | 6 | PM | 26310342 | 📋 | [Regulation of α-tocopherol on NFκB and Nrf2 signaling pathway at early stage of N-nitrosomethylbenzylamine⁃induced human esophageal cell carcinogenesis] |
| Vitamin E | Esophageal Cancer | 2 | PM | 22223226 | 📋 | Time-selective Chemoprevention of Vitamin E and Selenium on Esophageal Carcinogenesis in Rats: The Possible Role of Nuclear Factor kappaB Signaling Pathway |
| Vitamin E | Esophageal Cancer | 1 | PM | 18444134 | 📋 | Dietary supplement use and risk of neoplastic progression in esophageal adenocarcinoma: a prospective study |
| Vitamin E | Gastric Cancer | 4 | PM | 37055846 | 📋 | γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway |
| Vitamin E | Gastric Cancer | 3 | PM | 35695929 | 📋 | Diet and gastric cancer risk: an umbrella review of systematic reviews and meta-analyses of prospective cohort studies |
| Vitamin E | Gastric Cancer | 1 | PM | 18669867 | 📋 | Dietary intake of selected micronutrients and gastric cancer risk: an Italian case-control study |
| Vitamin E | Gastric Cancer | 2 | PM | 18081943 | 📋 | Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling |
| Vitamin E | Glioblastoma | 2 | PM | 37283489 | 📋 | Involvement of oxidative stress-related apoptosis in chlorpyrifos-induced cytotoxicity and the ameliorating potential of the antioxidant vitamin E in human glioblastoma cells |
| Vitamin E | Glioblastoma | 1 | PM | 34136195 | 📋 | Antioxidant vitamins promote anticancer effects on low-concentration methotrexate-treated glioblastoma cells via enhancing the caspase-3 death pathway |
| Vitamin E | Glioma | 1 | PM | 25221872 | 📋 | Tocotrienol-rich Fraction, [6]-gingerol and Epigallocatechin Gallate Inhibit Proliferation and Induce Apoptosis of Glioma Cancer Cells |
| Vitamin E | Lung Cancer | 2 | PM | 31077299 | 📋 | A Prospective Study of Serum Vitamin E and 28-Year Risk of Lung Cancer |
| Vitamin E | Lung Cancer | 1 | PM | 26131295 | 📋 | Dietary vitamin E intake could reduce the risk of lung cancer: evidence from a meta-analysis |
| Vitamin E | Lymphoma | 1 | PM | 28806414 | 📋 | Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK |
| Vitamin E | Melanoma | 1 | PM | 27055589 | 📋 | γ-Tocotrienol Upregulates Aryl Hydrocarbon Receptor Expression and Enhances the Anticancer Effect of Baicalein |
| Vitamin E | Melanoma | 2 | PM | 26427039 | 📋 | Sub-apoptotic dosages of pro-oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysis |
| Vitamin E | Oral Cancer | 1 | PM | 28818030 | 📋 | Vitamin E (α-Tocopherol) Exhibits Antitumour Activity on Oral Squamous Carcinoma Cells ORL-48 |
| Vitamin E | Oral Cancer | 2 | PM | 25339003 | 📋 | High serum level of retinol and α-tocopherol affords protection against oral cancer in a multiethnic population |
| Vitamin E | Pancreatic Cancer | 11 | PM | 37389119 | 📋 | Vitamin E in the management of pancreatic cancer: A scoping review |
| Vitamin E | Pancreatic Cancer | 9 | PM | 31367187 | 📋 | Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIP s |
| Vitamin E | Pancreatic Cancer | 4 | PM | 31100111 | 📋 | Vitamin C and Vitamin E Mitigate the Risk of Pancreatic Ductal Adenocarcinoma from Meat-Derived Mutagen Exposure in Adults in a Case-Control Study |
| Vitamin E | Pancreatic Cancer | 3 | PM | 30630552 | 📋 | Dietary and circulating vitamin C, vitamin E, β-carotene and risk of total cardiovascular mortality: a systematic review and dose-response meta-analysis of prospective observational studies |
| Vitamin E | Pancreatic Cancer | 8 | PM | 28404939 | 📋 | δ-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis |
| Vitamin E | Pancreatic Cancer | 1 | PM | 27356952 | 📋 | Association Between Intake of Antioxidants and Pancreatic Cancer Risk: A Meta-Analysis |
| Vitamin E | Pancreatic Cancer | 6 | PM | 26844278 | 📋 | A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia |
| Vitamin E | Pancreatic Cancer | 10 | PM | 25997867 | 📋 | EGR-1/Bax pathway plays a role in vitamin E δ-tocotrienol-induced apoptosis in pancreatic cancer cells |
| Vitamin E | Pancreatic Cancer | 2 | PM | 25929754 | 📋 | Vitamin E intake and pancreatic cancer risk: a meta-analysis of observational studies |
| Vitamin E | Pancreatic Cancer | 7 | PM | 21971120 | 📋 | Vitamin E δ-tocotrienol augments the antitumor activity of gemcitabine and suppresses constitutive NF-κB activation in pancreatic cancer |
| Vitamin E | Pancreatic Cancer | 5 | PM | 20530201 | 📋 | Dietary intake of selected micronutrients and the risk of pancreatic cancer: an Italian case-control study |
| Vitamin E | Prostate Cancer | 15 | PM | 38734077 | 📋 | Different roles of natural forms of vitamin E in chemoprevention and treatment of prostate cancer |
| Vitamin E | Prostate Cancer | 14 | PM | 35197557 | 📋 | A 28-year prospective analysis of serum vitamin E, vitamin E-related genetic variation and risk of prostate cancer |
| Vitamin E | Prostate Cancer | 13 | PM | 35144931 | 📋 | δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp-/- mice |
| Vitamin E | Prostate Cancer | 11 | PM | 29491063 | 📋 | Suppressive Effect of Delta-Tocotrienol on Hypoxia Adaptation of Prostate Cancer Stem-like Cells |
| Vitamin E | Prostate Cancer | 10 | PM | 29225320 | 📋 | Combination Effect of δ-Tocotrienol and γ-Tocopherol on Prostate Cancer Cell Growth |
| Vitamin E | Prostate Cancer | 4 | PM | 26053590 | 📋 | Dietary, supplement, and adipose tissue tocopherol levels in relation to prostate cancer aggressiveness among African and European Americans: The North Carolina-Louisiana Prostate Cancer Project (PCaP) |
| Vitamin E | Prostate Cancer | 9 | PM | 23512990 | 📋 | Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1 |
| Vitamin E | Prostate Cancer | 5 | PM | 19383902 | 📋 | Associations between alpha-tocopherol, beta-carotene, and retinol and prostate cancer survival |
| Vitamin E | Prostate Cancer | 1 | PM | 18818108 | 📋 | Taxol Synergizes With Antioxidants in Inhibiting Hormal Refractory Prostate Cancer Cell Growth |
| Vitamin E | Prostate Cancer | 3 | PM | 18668529 | 📋 | Combination of Vitamin E and Selenium Causes an Induction of Apoptosis of Human Prostate Cancer Cells by Enhancing Bax/Bcl-2 Ratio |
| Vitamin E | Prostate Cancer | 8 | PM | 18059122 | 📋 | The role of vitamin E in the prevention of cancer: a meta-analysis of randomized controlled trials |
| Vitamin E | Prostate Cancer | 2 | PM | 17572195 | 📋 | Effect of Nutritional Supplement Challenge in Patients With Isolated High-Grade Prostatic Intraepithelial Neoplasia |
| Vitamin E | Prostate Cancer | 7 | PM | 16030104 | 📋 | Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer |
| Vitamin E | Prostate Cancer | 12 | PM | 14583501 | 📋 | Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells |
| Vitamin E | Prostate Cancer | 6 | PM | 9521168 | 📋 | Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial |
| Vitamin E | Renal Cell Carcinoma | 1 | PM | 28668878 | 📋 | Prognostic Importance of Vitamins A, E and Retinol-binding Protein 4 in Renal Cell Carcinoma Patients |
| Vitamin E | Thyroid Cancer | 4 | PM | 34230633 | 📋 | Histopathological prognosis of papillary thyroid carcinoma associated with nutritional status of vitamins A and E |
| Vitamin E | Thyroid Cancer | 1 | PM | 30935902 | 📋 | Effects of Curcumin and Its Adjuvant on TPC1 Thyroid Cell Line |
| Vitamin E | Thyroid Cancer | 3 | PM | 28806348 | 📋 | Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differentiated thyroid cancer: a randomized-controlled trial |
| Vitamin E | Thyroid Cancer | 2 | PM | 9179066 | 📋 | Selected micronutrient intake and thyroid carcinoma risk |
