| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Selenium | Acute Myeloid Leukemia | 1 | PM | 24872387 | 📋 | Selenium Suppresses Leukemia Through the Action of Endogenous Eicosanoids |
| Selenium | Bone Cancer | 1 | PM | 33901723 | 📋 | A concise review on the role of selenium for bone cancer applications |
| Selenium | Breast Cancer | 19 | PM | 39144222 | 📋 | The role of selenium intervention in gut microbiota homeostasis and gene function in mice with breast cancer on a high-fat diet |
| Selenium | Breast Cancer | 18 | PM | 37239017 | 📋 | Antiproliferative Effect of Inorganic and Organic Selenium Compounds in Breast Cell Lines |
| Selenium | Breast Cancer | 17 | PM | 36634075 | 📋 | Antitumor effect of selenium-rich Brazil nuts and selenomethionine dietary supplementation on pre-existing 4T1 mammary tumor growth in mice |
| Selenium | Breast Cancer | 16 | PM | 36483592 | 📋 | Fish Oil and Selenium with Doxorubicin Modulates Expression of Fatty Acid Receptors and Selenoproteins, and Targets Multiple Anti-Cancer Signaling in Triple-negative Breast Cancer Tumors |
| Selenium | Breast Cancer | 15 | PM | 34773240 | 📋 | Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis |
| Selenium | Breast Cancer | 14 | PM | 34525121 | 📋 | Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1 |
| Selenium | Breast Cancer | 13 | PM | 34520753 | 📋 | Selenite induced breast cancer MCF7 cells apoptosis through endoplasmic reticulum stress and oxidative stress pathway |
| Selenium | Breast Cancer | 12 | PM | 34447692 | 📋 | The Correlation Between Potential "Anti- Cancer" Trace Elements and the Risk of Breast Cancer: A Case-Control Study in a Chinese Population |
| Selenium | Breast Cancer | 11 | PM | 33935708 | 📋 | Chemopreventive and Anticancer Property of Selenoproteins in Obese Breast Cancer |
| Selenium | Breast Cancer | 10 | PM | 33809461 | 📋 | Serum Selenium Level Predicts 10-Year Survival after Breast Cancer |
| Selenium | Breast Cancer | 9 | PM | 33805447 | 📋 | Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice |
| Selenium | Breast Cancer | 8 | PM | 33723142 | 📋 | Anticancer potential of ascorbic acid and inorganic selenium on human breast cancer cell line MCF-7 and colon carcinoma HCT-116 |
| Selenium | Breast Cancer | 7 | PM | 33420696 | 📋 | Relationship Between Selenium in Human Tissues and Breast Cancer: a Meta-analysis Based on Case-Control Studies |
| Selenium | Breast Cancer | 6 | PM | 32956826 | 📋 | Nutritional Supplements in Combination with Chemotherapy or Targeted Therapy Reduces Tumor Progression in Mice bearing Triple-negative Breast Cancer |
| Selenium | Breast Cancer | 5 | PM | 32905216 | 📋 | Selenium donors inhibits osteoclastogenesis through inhibiting IL-6 and plays a pivotal role in bone metastasis from breast cancer |
| Selenium | Breast Cancer | 4 | PM | 32378183 | 📋 | Pre-diagnostic Serum Selenium Levels in Relation to Breast Cancer Survival and Tumor Characteristics |
| Selenium | Breast Cancer | 3 | PM | 32040846 | 📋 | Bisphenol A-Induced Cell Proliferation and Mitochondrial Oxidative Stress Are Diminished via Modulation of TRPV1 Channel in Estrogen Positive Breast Cancer Cell by Selenium Treatment |
| Selenium | Breast Cancer | 2 | PM | 27055401 | 📋 | Selenium Potentiates the Anticancer Effect of Cisplatin Against Oxidative Stress and Calcium Ion Signaling-Induced Intracellular Toxicity in MCF-7 Breast Cancer Cells: Involvement of the TRPV1 Channel |
| Selenium | Breast Cancer | 1 | PM | 15894690 | 📋 | Increased Rates of Chromosome Breakage in BRCA1 Carriers Are Normalized by Oral Selenium Supplementation |
| Selenium | Cancer | 13 | PM | 37686861 | 📋 | Selenium in Cancer Rehabilitation-A Retrospective Study from a Specialized Clinic |
| Selenium | Cancer | 11 | PM | 36678733 | 📋 | Selenium-Containing Agents Acting on Cancer-A New Hope? |
| Selenium | Cancer | 12 | PM | 36379613 | 📋 | Combination of Se-methylselenocysteine, D-α-tocopheryl succinate, β-carotene, and L-lysine can prevent cancer metastases using as an adjuvant therapy |
| Selenium | Cancer | 10 | PM | 35956408 | 📋 | Selenium Yeast and Fish Oil Combination Diminishes Cancer Stem Cell Traits and Reverses Cisplatin Resistance in A549 Sphere Cells |
| Selenium | Cancer | 9 | PM | 35216330 | 📋 | Potential Role of Selenium in the Treatment of Cancer and Viral Infections |
| Selenium | Cancer | 8 | PM | 34935169 | 📋 | The emerging role of selenium metabolic pathways in cancer: New therapeutic targets for cancer |
| Selenium | Cancer | 7 | PM | 34769276 | 📋 | Antitumor Effects of Selenium |
| Selenium | Cancer | 6 | PM | 34392068 | 📋 | Selenium stimulates the antitumour immunity: Insights to future research |
| Selenium | Cancer | 5 | PM | 34068374 | 📋 | Selenium as a Bioactive Micronutrient in the Human Diet and Its Cancer Chemopreventive Activity |
| Selenium | Cancer | 4 | PM | 33706760 | 📋 | A pan-cancer study of selenoprotein genes as promising targets for cancer therapy |
| Selenium | Cancer | 3 | PM | 33498364 | 📋 | Selenium Compounds as Novel Potential Anticancer Agents |
| Selenium | Cancer | 2 | PM | 32998101 | 📋 | Recent advances in clinical studies of selenium supplementation in radiotherapy |
| Selenium | Cancer | 1 | PM | 31963404 | 📋 | Selenium Anticancer Properties and Impact on Cellular Redox Status |
| Selenium | Cervical Cancer | 8 | PM | 38576048 | 📋 | Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer |
| Selenium | Cervical Cancer | 7 | PM | 38154440 | 📋 | Selenium promotes immunogenic radiotherapy against cervical cancer metastasis through evoking P53 activation |
| Selenium | Cervical Cancer | 6 | PM | 36609649 | 📋 | Association of Plasma Selenium and Its Untargeted Metabolomic Profiling with Cervical Cancer Prognosis |
| Selenium | Cervical Cancer | 5 | PM | 36108716 | 📋 | Sodium selenite inhibits cervical cancer growth via ROS mediated AMPK/FOXO3a /GADD45a axis |
| Selenium | Cervical Cancer | 4 | PM | 33754876 | 📋 | Therapeutic Potential of Selenium and Selenium Compounds in Cervical Cancer |
| Selenium | Cervical Cancer | 3 | PM | 28739737 | 📋 | Synergistic Effects of SAM and Selenium Compounds on Proliferation, Migration and Adhesion of HeLa Cells |
| Selenium | Cervical Cancer | 1 | PM | 20133068 | 📋 | Multicenter, Phase 3 Trial Comparing Selenium Supplementation With Observation in Gynecologic Radiation Oncology |
| Selenium | Cervical Cancer | 2 | PM | 1495753 | 📋 | Chemopreventive Action of Selenium on Methylcholanthrene-Induced Carcinogenesis in the Uterine Cervix of Mouse |
| Selenium | Cisplatin Toxicity | 3 | PM | 30687122 | 📋 | Selenium-Containing Protein From Selenium-Enriched Spirulina platensis Attenuates Cisplatin-Induced Apoptosis in MC3T3-E1 Mouse Preosteoblast by Inhibiting Mitochondrial Dysfunction and ROS-Mediated Oxidative Damage |
| Selenium | Cisplatin Toxicity | 2 | PM | 26514460 | 📋 | Protective Role of Selenium and High Dose Vitamin E Against Cisplatin - Induced Nephrotoxicty in Rats |
| Selenium | Cisplatin Toxicity | 1 | PM | 26108027 | 📋 | Selenium Protects Cerebral Cells by Cisplatin Induced Neurotoxicity |
| Selenium | Colon Cancer | 6 | PM | 35201430 | 📋 | Selenite-induced ROS/AMPK/FoxO3a/GABARAPL-1 signaling pathway modulates autophagy that antagonize apoptosis in colorectal cancer cells |
| Selenium | Colon Cancer | 5 | PM | 33723142 | 📋 | Anticancer potential of ascorbic acid and inorganic selenium on human breast cancer cell line MCF-7 and colon carcinoma HCT-116 |
| Selenium | Colon Cancer | 1 | PM | 28045589 | 📋 | Dietary Selenium Protects Adiponectin Knockout Mice Against Chronic Inflammation Induced Colon Cancer |
| Selenium | Colon Cancer | 2 | PM | 26094214 | 📋 | Synergy Between Sulforaphane and Selenium in Protection Against Oxidative Damage in Colonic CCD841 Cells |
| Selenium | Colon Cancer | 4 | PM | 18570215 | 📋 | Role of Nigella Sativa and a Number of Its Antioxidant Constituents Towards Azoxymethane-Induced Genotoxic Effects and Colon Cancer in Rats |
| Selenium | Colon Cancer | 3 | PM | 16627976 | 📋 | Selenomethionine Induces p53 Mediated Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells |
| Selenium | Colorectal Cancer | 7 | PM | 39330493 | 📋 | Selenium, Zinc, and Plasma Total Antioxidant Status and the Risk of Colorectal Adenoma and Cancer |
| Selenium | Colorectal Cancer | 6 | PM | 38691306 | 📋 | Research on the Effect and Mechanism of Selenium on Colorectal Cancer Through TRIM32 |
| Selenium | Colorectal Cancer | 5 | PM | 36191991 | 📋 | The Complex Composition of Trans-resveratrol, Quercetin, Vitamin E and Selenium Inhibits the Growth of Colorectal Carcinoma |
| Selenium | Colorectal Cancer | 4 | PM | 35287753 | 📋 | Calcium intake may explain the reduction of colorectal cancer odds by dietary selenium - a case-control study in Poland |
| Selenium | Colorectal Cancer | 3 | PM | 35201430 | 📋 | Selenite-induced ROS/AMPK/FoxO3a/GABARAPL-1 signaling pathway modulates autophagy that antagonize apoptosis in colorectal cancer cells |
| Selenium | Colorectal Cancer | 2 | PM | 35158204 | 📋 | Selenium binding protein 1 inhibits tumor angiogenesis in colorectal cancers by blocking the Delta-like ligand 4/Notch1 signaling pathway |
| Selenium | Colorectal Cancer | 1 | PM | 32274393 | 📋 | The Pro-Oxidant, Apoptotic and Anti-Angiogenic Effects of Selenium Supplementation on Colorectal Tumors Induced by 1,2-Dimethylhydrazine in BALB/C Mice |
| Selenium | Endometrial Cancer | 2 | PM | 35267933 | 📋 | An Assessment of Serum Selenium Concentration in Women with Endometrial Cancer |
| Selenium | Endometrial Cancer | 1 | PM | 20133068 | 📋 | Multicenter, Phase 3 Trial Comparing Selenium Supplementation With Observation in Gynecologic Radiation Oncology |
| Selenium | Esophageal Cancer | 3 | PM | 35628320 | 📋 | Potential Chemotherapeutic Effect of Selenium for Improved Canceration of Esophageal Cancer |
| Selenium | Esophageal Cancer | 2 | PM | 33132349 | 📋 | Inhibitory Effect of Selenium on Esophagus Cancer Cells and the Related Mechanism |
| Selenium | Esophageal Cancer | 1 | PM | 22223226 | 📋 | Time-selective Chemoprevention of Vitamin E and Selenium on Esophageal Carcinogenesis in Rats: The Possible Role of Nuclear Factor kappaB Signaling Pathway |
| Selenium | Gastric Cancer | 3 | PM | 37351758 | 📋 | Co-exposure to iron, copper, zinc, selenium and titanium is associated with the prevention of gastric precancerous lesions |
| Selenium | Gastric Cancer | 2 | PM | 33098836 | 📋 | Effect of chitosan oligosaccharide-conjugated selenium on improving immune function and blocking gastric cancer growth |
| Selenium | Gastric Cancer | 1 | PM | 12500663 | 📋 | Redifferentiation of Human Gastric Cancer Cells Induced by Ascorbic Acid and Sodium Selenite |
| Selenium | Glioblastoma | 1 | PM | 34121995 | 📋 | Therapeutic Potential of Selenium in Glioblastoma |
| Selenium | Leukemia | 1 | PM | 33723167 | 📋 | Antitumor effects of sodium selenite on acute lymphocytic leukemia |
| Selenium | Liver Cancer | 7 | PM | 36563868 | 📋 | Oxygen therapy accelerates apoptosis induced by selenium compounds via regulating Nrf2/MAPK signaling pathway in hepatocellular carcinoma |
| Selenium | Liver Cancer | 6 | PM | 34586726 | 📋 | Selenium sulfide disrupts the PLAGL2/C-MET/STAT3-induced resistance against mitochondrial apoptosis in hepatocellular carcinoma |
| Selenium | Liver Cancer | 5 | PM | 34231234 | 📋 | Diminished CCl 4 -induced hepatocellular carcinoma, oxidative stress, and apoptosis by co-administration of curcumin or selenium in mice |
| Selenium | Liver Cancer | 4 | PM | 34162153 | 📋 | A novel therapeutic strategy for hepatocellular carcinoma: Immunomodulatory mechanisms of selenium and/or selenoproteins on a shift towards anti-cancer |
| Selenium | Liver Cancer | 3 | PM | 33248145 | 📋 | Selenium enrichment improves anti-proliferative effect of oolong tea extract on human hepatoma HuH-7 cells |
| Selenium | Liver Cancer | 1 | PM | 26522247 | 📋 | Anti-tumor and Immunomodulatory Activity of Selenium (Se)-polysaccharide From Se-enriched Grifola Frondosa |
| Selenium | Liver Cancer | 2 | PM | 20380634 | 📋 | Selenium in the Prevention and Treatment of Hepatocellular Carcinoma |
| Selenium | Lung Cancer | 4 | PM | 37994159 | 📋 | Selenium enhances photodynamic therapy of C-phycocyanin against lung cancer via dual regulation of cytotoxicity and antioxidant activity |
| Selenium | Lung Cancer | 3 | PM | 36547898 | 📋 | Targeting EGFR in Combination with Nutritional Supplements on Antitumor Efficacy in a Lung Cancer Mouse Model |
| Selenium | Lung Cancer | 2 | PM | 32751169 | 📋 | Omega-3 Fatty Acid-Enriched Fish Oil and Selenium Combination Modulates Endoplasmic Reticulum Stress Response Elements and Reverses Acquired Gefitinib Resistance in HCC827 Lung Adenocarcinoma Cells |
| Selenium | Lung Cancer | 1 | PM | 25053624 | 📋 | Consumption of a High-Fat Diet Abrogates Inhibitory Effects of Methylseleninic Acid on Spontaneous Metastasis of Lewis Lung Carcinoma in Mice |
| Selenium | Ovarian Cancer | 3 | PM | 36768241 | 📋 | High-Dose Selenium Induces Ferroptotic Cell Death in Ovarian Cancer |
| Selenium | Ovarian Cancer | 2 | PM | 31290351 | 📋 | Modulation of Selenium-Dependent Glutathione Peroxidase Activity Enhances Doxorubicin-Induced Apoptosis, Tumour Cell Killing and Hydroxyl Radical Production in Human NCI/ADR-RES Cancer Cells Despite High-Level P-glycoprotein Expression |
| Selenium | Ovarian Cancer | 1 | PM | 28202637 | 📋 | Supplemental Selenium May Decrease Ovarian Cancer Risk in African-American Women |
| Selenium | Pancreatic Cancer | 3 | PM | 38029455 | 📋 | Organic Selenium induces ferroptosis in pancreatic cancer cells |
| Selenium | Pancreatic Cancer | 1 | PM | 27356952 | 📋 | Association Between Intake of Antioxidants and Pancreatic Cancer Risk: A Meta-Analysis |
| Selenium | Pancreatic Cancer | 4 | PM | 23280534 | 📋 | Antioxidant intake and pancreatic cancer risk: the Vitamins and Lifestyle (VITAL) Study |
| Selenium | Pancreatic Cancer | 2 | PM | 2365502 | 📋 | Inhibitory Effect of Selenium on Hamster Pancreatic Cancer Induction by N'-nitrosobis(2-oxopropyl)amine |
| Selenium | Prostate Cancer | 13 | PM | 38608596 | 📋 | Effects of natural extract interventions in prostate cancer: A systematic review and network meta-analysis |
| Selenium | Prostate Cancer | 12 | PM | 37765058 | 📋 | Selenium in Prostate Cancer: Prevention, Progression, and Treatment |
| Selenium | Prostate Cancer | 11 | PM | 35406784 | 📋 | Necroptosis and Prostate Cancer: Molecular Mechanisms and Therapeutic Potential |
| Selenium | Prostate Cancer | 5 | PM | 31861307 | 📋 | Selenium Supplementation and Prostate Health in a New Zealand Cohort |
| Selenium | Prostate Cancer | 6 | PM | 28076331 | 📋 | A Short-Term Intervention With Selenium Affects Expression of Genes Implicated in the Epithelial-To-Mesenchymal Transition in the Prostate |
| Selenium | Prostate Cancer | 3 | PM | 27406859 | 📋 | Tomato-based Randomized Controlled Trial in Prostate Cancer Patients: Effect on PSA |
| Selenium | Prostate Cancer | 4 | PM | 21419321 | 📋 | Selenium Glycinate Supplementation Increases Blood Glutathione Peroxidase Activities and Decreases Prostate-Specific Antigen Readings in Middle-Aged US Men |
| Selenium | Prostate Cancer | 1 | PM | 21048810 | 📋 | The Safety and Efficacy of a Silymarin and Selenium Combination in Men After Radical Prostatectomy - A Six Month Placebo-Controlled Double-Blind Clinical Trial |
| Selenium | Prostate Cancer | 8 | PM | 18668529 | 📋 | Combination of Vitamin E and Selenium Causes an Induction of Apoptosis of Human Prostate Cancer Cells by Enhancing Bax/Bcl-2 Ratio |
| Selenium | Prostate Cancer | 2 | PM | 17572195 | 📋 | Effect of Nutritional Supplement Challenge in Patients With Isolated High-Grade Prostatic Intraepithelial Neoplasia |
| Selenium | Prostate Cancer | 9 | PM | 16030104 | 📋 | Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer |
| Selenium | Prostate Cancer | 7 | PM | 14975747 | 📋 | Rapid Induction of Apoptosis in Prostate Cancer Cells by Selenium: Reversal by Metabolites of Arachidonate 5-lipoxygenase |
| Selenium | Prostate Cancer | 10 | PM | 14583501 | 📋 | Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells |
| Selenium | Thyroid Cancer | 4 | PM | 39399620 | 📋 | Serum Selenium Level in Thyroid Cancer: A Case-Control Study |
| Selenium | Thyroid Cancer | 3 | PM | 38027150 | 📋 | The association between serum selenium levels and pathological features of papillary thyroid cancer in 284 patients |
| Selenium | Thyroid Cancer | 2 | PM | 36481604 | 📋 | Selenium, selenoproteins and cancer of the thyroid |
| Selenium | Thyroid Cancer | 1 | PM | 12117262 | 📋 | Concentration of Selenium in the Whole Blood and the Thyroid Tissue of Patients With Various Thyroid Diseases |
