| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Fisetin | Acute Promyelocytic Leukemia | 2 | PM | 26081618 | 📋 | The pleiotropic effects of fisetin and hesperetin on human acute promyelocytic leukemia cells are mediated through apoptosis, cell cycle arrest, and alterations in signaling networks |
| Fisetin | Acute Promyelocytic Leukemia | 1 | PM | 11841797 | 📋 | Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease |
| Fisetin | Biliary Tract Cancer | 1 | PM | 27793939 | 📋 | Fisetin Reduces Cell Viability Through Up-Regulation of Phosphorylation of ERK1/2 in Cholangiocarcinoma Cells |
| Fisetin | Bladder Cancer | 1 | PM | 34836005 | 📋 | Kaempferol, Myricetin and Fisetin in Prostate and Bladder Cancer: A Systematic Review of the Literature |
| Fisetin | Bladder Cancer | 2 | PM | 21054790 | 📋 | Fisetin, a dietary flavonoid, induces cell cycle arrest and apoptosis through activation of p53 and inhibition of NF-kappa B pathways in bladder cancer cells |
| Fisetin | Bone Cancer | 3 | PM | 31044527 | 📋 | Fisetin activates Hippo pathway and JNK/ERK/AP-1 signaling to inhibit proliferation and induce apoptosis of human osteosarcoma cells via ZAK overexpression |
| Fisetin | Bone Cancer | 2 | PM | 31028200 | 📋 | Fistein Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion via Affecting FAK, uPA and NF-ĸB Signaling Pathway In Vitro |
| Fisetin | Bone Cancer | 1 | PM | 29270805 | 📋 | Combination of etoposide and fisetin results in anti-cancer efficiency against osteosarcoma cell models |
| Fisetin | Breast Cancer | 14 | PM | 37480513 | 📋 | Naringenin in combination with quercetin/fisetin shows synergistic anti-proliferative and migration reduction effects in breast cancer cell lines |
| Fisetin | Breast Cancer | 10 | PM | 37047366 | 📋 | Antiproliferative Mechanisms of a Polyphenolic Combination of Kaempferol and Fisetin in Triple-Negative Breast Cancer Cells |
| Fisetin | Breast Cancer | 9 | PM | 36273436 | 📋 | Study of quercetin and fisetin synergistic effect on breast cancer and potentially involved signaling pathways |
| Fisetin | Breast Cancer | 8 | PM | 35989353 | 📋 | Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells |
| Fisetin | Breast Cancer | 1 | PM | 31898540 | 📋 | Phytochemicals Inhibit Migration of Triple Negative Breast Cancer Cells by Targeting Kinase Signaling |
| Fisetin | Breast Cancer | 5 | PM | 30431692 | 📋 | Fisetin induces apoptosis in breast cancer MDA-MB-453 cells through degradation of HER2/neu and via the PI3K/Akt pathway |
| Fisetin | Breast Cancer | 3 | PM | 30108501 | 📋 | Fisetin Inhibited Growth and Metastasis of Triple-Negative Breast Cancer by Reversing Epithelial-to-Mesenchymal Transition via PTEN/Akt/GSK3β Signal Pathway |
| Fisetin | Breast Cancer | 6 | PM | 30076913 | 📋 | Fisetin inhibits cell migration via inducing HO-1 and reducing MMPs expression in breast cancer cell lines |
| Fisetin | Breast Cancer | 4 | PM | 29749427 | 📋 | Anti‑cancer effects of fisetin on mammary carcinoma cells via regulation of the PI3K/Akt/mTOR pathway: In vitro and in vivo studies |
| Fisetin | Breast Cancer | 7 | PM | 28119082 | 📋 | A hydroxylated flavonol, fisetin inhibits the formation of a carcinogenic estrogen metabolite |
| Fisetin | Breast Cancer | 2 | PM | 28004315 | 📋 | Bioflavonoid Fisetin Loaded α-Tocopherol-Poly(lactic acid)-Based Polymeric Micelles for Enhanced Anticancer Efficacy in Breast Cancers |
| Fisetin | Breast Cancer | 13 | PM | 26755433 | 📋 | The Dietary Flavonoid Fisetin Causes Cell Cycle Arrest, Caspase-Dependent Apoptosis, and Enhanced Cytotoxicity of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells |
| Fisetin | Breast Cancer | 12 | PM | 26101063 | 📋 | Fisetin regulates TPA-induced breast cell invasion by suppressing matrix metalloproteinase-9 activation via the PKC/ROS/MAPK pathways |
| Fisetin | Breast Cancer | 11 | PM | 21922137 | 📋 | Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy |
| Fisetin | Cancer | 22 | PM | 37960338 | 📋 | Role of Fisetin in Selected Malignant Neoplasms in Women |
| Fisetin | Cancer | 21 | PM | 37626424 | 📋 | Biological effects and mechanisms of fisetin in cancer: a promising anti-cancer agent |
| Fisetin | Cancer | 20 | PM | 37565061 | 📋 | Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies |
| Fisetin | Cancer | 14 | PM | 37194231 | 📋 | The Role of Phytochemicals in Cancer Prevention: A Review with Emphasis on Baicalein, Fisetin, and Biochanin A |
| Fisetin | Cancer | 13 | PM | 36558146 | 📋 | The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment |
| Fisetin | Cancer | 12 | PM | 35885908 | 📋 | Specific Irreversible Cell-Cycle Arrest and Depletion of Cancer Cells Obtained by Combining Curcumin and the Flavonoids Quercetin and Fisetin |
| Fisetin | Cancer | 11 | PM | 35807785 | 📋 | Fisetin, a Potent Anticancer Flavonol Exhibiting Cytotoxic Activity against Neoplastic Malignant Cells and Cancerous Conditions: A Scoping, Comprehensive Review |
| Fisetin | Cancer | 9 | PM | 35743290 | 📋 | A Small Molecule That Promotes Cellular Senescence Prevents Fibrogenesis and Tumorigenesis |
| Fisetin | Cancer | 8 | PM | 34302980 | 📋 | Cancer chemopreventive role of fisetin: Regulation of cell signaling pathways in different cancers |
| Fisetin | Cancer | 7 | PM | 34267320 | 📋 | Novel role of the dietary flavonoid fisetin in suppressing rRNA biogenesis |
| Fisetin | Cancer | 6 | PM | 33806779 | 📋 | The Interaction of the Flavonoid Fisetin with Human Glutathione Transferase A1-1 |
| Fisetin | Cancer | 5 | PM | 33473265 | 📋 | Fisetin: An anticancer perspective |
| Fisetin | Cancer | 1 | PM | 31064104 | 📋 | Fisetin and Quercetin: Promising Flavonoids With Chemopreventive Potential |
| Fisetin | Cancer | 18 | PM | 29225112 | 📋 | Fisetin: A bioactive phytochemical with potential for cancer prevention and pharmacotherapy |
| Fisetin | Cancer | 19 | PM | 29136771 | 📋 | A review on the chemotherapeutic potential of fisetin: In vitro evidences |
| Fisetin | Cancer | 2 | PM | 28052097 | 📋 | The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways |
| Fisetin | Cancer | 4 | PM | 27377217 | 📋 | The flavonoid fisetin as an anticancer agent targeting the growth signaling pathways |
| Fisetin | Cancer | 10 | PM | 27163728 | 📋 | Exploring the molecular targets of dietary flavonoid fisetin in cancer |
| Fisetin | Cancer | 17 | PM | 27059089 | 📋 | Dietary flavonoid fisetin for cancer prevention and treatment |
| Fisetin | Cancer | 16 | PM | 23293889 | 📋 | Inhibition of Akt/mTOR signaling by the dietary flavonoid fisetin |
| Fisetin | Cancer | 3 | PM | 23121441 | 📋 | Fisetin: a dietary antioxidant for health promotion |
| Fisetin | Cancer | 15 | PM | 22139440 | 📋 | Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angioprevention |
| Fisetin | Cervical Cancer | 1 | PM | 35163629 | 📋 | Fisetin Deters Cell Proliferation, Induces Apoptosis, Alleviates Oxidative Stress and Inflammation in Human Cancer Cells, HeLa |
| Fisetin | Cervical Cancer | 4 | PM | 26662956 | 📋 | Synergistic effect of fisetin combined with sorafenib in human cervical cancer HeLa cells through activation of death receptor-5 mediated caspase-8/caspase-3 and the mitochondria-dependent apoptotic pathway |
| Fisetin | Cervical Cancer | 3 | PM | 23940799 | 📋 | Fisetin inhibits migration and invasion of human cervical cancer cells by down-regulating urokinase plasminogen activator expression through suppressing the p38 MAPK-dependent NF-κB signaling pathway |
| Fisetin | Cervical Cancer | 2 | PM | 21964635 | 📋 | Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8-/caspase-3-dependent pathway |
| Fisetin | Chronic Lymphocytic Leukemia | 1 | PM | 27489195 | 📋 | Potentiation of Luteolin Cytotoxicity by Flavonols Fisetin and Quercetin in Human Chronic Lymphocytic Leukemia Cell Lines |
| Fisetin | Chronic Myeloid Leukemia | 2 | PM | 31638196 | 📋 | Cellular and molecular alterations induced by low‑dose fisetin in human chronic myeloid leukemia cells |
| Fisetin | Chronic Myeloid Leukemia | 1 | PM | 26408178 | 📋 | Fisetin and hesperetin induced apoptosis and cell cycle arrest in chronic myeloid leukemia cells accompanied by modulation of cellular signaling |
| Fisetin | Colon Cancer | 4 | PM | 37174126 | 📋 | Senolytic Flavonoids Enhance Type-I and Type-II Cell Death in Human Radioresistant Colon Cancer Cells through AMPK/MAPK Pathway |
| Fisetin | Colon Cancer | 8 | PM | 25840992 | 📋 | Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter |
| Fisetin | Colon Cancer | 7 | PM | 24019108 | 📋 | N-acetyl-L-cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells |
| Fisetin | Colon Cancer | 6 | PM | 23840275 | 📋 | HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells |
| Fisetin | Colon Cancer | 5 | PM | 20974518 | 📋 | Securin depletion sensitizes human colon cancer cells to fisetin-induced apoptosis |
| Fisetin | Colon Cancer | 1 | PM | 19264955 | 📋 | Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin |
| Fisetin | Colon Cancer | 2 | PM | 19037088 | 📋 | A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways |
| Fisetin | Colon Cancer | 3 | PM | 16317137 | 📋 | Fisetin inhibits the activities of cyclin-dependent kinases leading to cell cycle arrest in HT-29 human colon cancer cells |
| Fisetin | Colorectal Cancer | 9 | PM | 38748229 | 📋 | Fisetin and/or capecitabine causes changes in apoptosis pathways in capecitabine-resistant colorectal cancer cell lines |
| Fisetin | Colorectal Cancer | 8 | PM | 37801904 | 📋 | Fisetin induces the upregulation of AKAP12 mRNA and anti-angiogenesis in a patient-derived organoid xenograft model |
| Fisetin | Colorectal Cancer | 7 | PM | 37634766 | 📋 | Fisetin overcomes non-targetability of mutated KRAS induced YB-1 signaling in colorectal cancer cells and improves radiosensitivity by blocking repair of radiation-induced DNA double-strand breaks |
| Fisetin | Colorectal Cancer | 6 | PM | 37450699 | 📋 | Fisetin induces apoptosis in colorectal cancer cells by suppressing autophagy and down-regulating nuclear factor erythroid 2-related factor 2 (Nrf2) |
| Fisetin | Colorectal Cancer | 3 | PM | 31018249 | 📋 | Fisetin and 5-fluorouracil: Effective combination for PIK3CA-mutant colorectal cancer |
| Fisetin | Colorectal Cancer | 4 | PM | 29574877 | 📋 | Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo |
| Fisetin | Colorectal Cancer | 1 | PM | 29541713 | 📋 | Effect of fisetin supplementation on inflammatory factors and matrix metalloproteinase enzymes in colorectal cancer patients |
| Fisetin | Colorectal Cancer | 2 | PM | 28105204 | 📋 | Combining fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in xenograft tumor models |
| Fisetin | Colorectal Cancer | 5 | PM | 20637980 | 📋 | Enhancement of p53-mutant human colorectal cancer cells radiosensitivity by flavonoid fisetin |
| Fisetin | Endometrial Cancer | 1 | PM | 28119082 | 📋 | A hydroxylated flavonol, fisetin inhibits the formation of a carcinogenic estrogen metabolite |
| Fisetin | Gastric Cancer | 3 | PM | 35566228 | 📋 | Bioactivity of Two Polyphenols Quercetin and Fisetin against Human Gastric Adenocarcinoma AGS Cells as Affected by Two Coexisting Proteins |
| Fisetin | Gastric Cancer | 2 | PM | 29805580 | 📋 | Fisetin inhibits the proliferation of gastric cancer cells and induces apoptosis through suppression of ERK 1/2 activation |
| Fisetin | Gastric Cancer | 1 | PM | 27254419 | 📋 | Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells |
| Fisetin | Glioblastoma | 2 | PM | 38423634 | 📋 | Genotoxic and Cytotoxic Activity of Fisetin on Glioblastoma Cells |
| Fisetin | Glioblastoma | 1 | PM | 35057010 | 📋 | Neuroimmunomodulatory Properties of Flavonoids and Derivates: A Potential Action as Adjuvants for the Treatment of Glioblastoma |
| Fisetin | Glioma | 1 | PM | 31421049 | 📋 | Fisetin effects on cell proliferation and apoptosis in glioma cells |
| Fisetin | Glioma | 2 | PM | 25527158 | 📋 | Fisetin suppresses ADAM9 expression and inhibits invasion of glioma cancer cells through increased phosphorylation of ERK1/2 |
| Fisetin | Head and Neck Cancer | 6 | PM | 38801393 | 📋 | Fisetin induces G2/M phase arrest and caspase-mediated cleavage of p21Cip1 and p27Kip1 leading to apoptosis and tumor growth inhibition in HNSCC |
| Fisetin | Head and Neck Cancer | 5 | PM | 37371038 | 📋 | Kaempferol and Fisetin-Related Signaling Pathways Induce Apoptosis in Head and Neck Cancer Cells |
| Fisetin | Head and Neck Cancer | 4 | PM | 36631292 | 📋 | Fisetin, a dietary flavonoid, increases the sensitivity of chemoresistant head and neck carcinoma cells to cisplatin possibly through HSP90AA1/IL-17 pathway |
| Fisetin | Head and Neck Cancer | 3 | PM | 33807530 | 📋 | Anticancer Potential of Selected Flavonols: Fisetin, Kaempferol, and Quercetin on Head and Neck Cancers |
| Fisetin | Head and Neck Cancer | 2 | PM | 30936621 | 📋 | Induction of sestrin 2 is associated with fisetin-mediated apoptosis in human head and neck cancer cell lines |
| Fisetin | Head and Neck Cancer | 1 | PM | 27551764 | 📋 | Fisetin inhibits laryngeal carcinoma through regulation of AKT/NF-κB/mTOR and ERK1/2 signaling pathways |
| Fisetin | Kidney Cancer | 1 | PM | 30411496 | 📋 | Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell |
| Fisetin | Kidney Cancer | 2 | PM | 28767099 | 📋 | Fisetin Induces Apoptosis Through p53-Mediated Up-Regulation of DR5 Expression in Human Renal Carcinoma Caki Cells |
| Fisetin | Leukemia | 1 | PM | 31096772 | 📋 | Fisetin Inhibits Cell Proliferation through the Induction of G 0/G 1 Phase Arrest and Caspase-3-Mediated Apoptosis in Mouse Leukemia Cells |
| Fisetin | Leukemia | 3 | PM | 25973292 | 📋 | Nitric oxide is the key mediator of death induced by fisetin in human acute monocytic leukemia cells |
| Fisetin | Leukemia | 2 | PM | 20025993 | 📋 | The dietary flavonoids myricetin and fisetin act as dual inhibitors of DNA topoisomerases I and II in cells |
| Fisetin | Liver Cancer | 1 | PM | 37240422 | 📋 | Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer |
| Fisetin | Liver Cancer | 2 | PM | 33086879 | 📋 | Fisetin Inhibits Autophagy in HepG2 Cells via PI3K/Akt/mTOR and AMPK Pathway |
| Fisetin | Liver Cancer | 4 | PM | 31634424 | 📋 | Fisetin, a phytopolyphenol, targets apoptotic and necroptotic cell death in HepG2 cells |
| Fisetin | Liver Cancer | 8 | PM | 31261976 | 📋 | Inhibition of protein phosphatase 1 stimulates noncanonical ER stress eIF2α activation to enhance fisetin-induced chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells |
| Fisetin | Liver Cancer | 3 | PM | 28560391 | 📋 | Fisetin inhibits liver cancer growth in a mouse model: Relation to dopamine receptor |
| Fisetin | Liver Cancer | 5 | PM | 27522262 | 📋 | Structure related effects of flavonoid aglycones on cell cycle progression of HepG2 cells: Metabolic activation of fisetin and quercetin by catechol-O-methyltransferase (COMT) |
| Fisetin | Liver Cancer | 9 | PM | 26682000 | 📋 | Fisetin Modulates Antioxidant Enzymes and Inflammatory Factors to Inhibit Aflatoxin-B1 Induced Hepatocellular Carcinoma in Rats |
| Fisetin | Liver Cancer | 7 | PM | 20510331 | 📋 | Fisetin induces apoptosis in Huh-7 cells via downregulation of BIRC8 and Bcl2L2 |
| Fisetin | Liver Cancer | 6 | PM | 12107653 | 📋 | Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1 |
| Fisetin | Lung Cancer | 8 | PM | 35886884 | 📋 | Increase in Anticancer Drug-Induced Toxicity by Fisetin in Lung Adenocarcinoma A549 Spheroid Cells Mediated by the Reduction of Claudin-2 Expression |
| Fisetin | Lung Cancer | 7 | PM | 35733630 | 📋 | Exploration of Potential Targets and Mechanisms of Fisetin in the Treatment of Non-Small-Cell Lung Carcinoma via Network Pharmacology and In Vitro Validation |
| Fisetin | Lung Cancer | 6 | PM | 34648968 | 📋 | eIF3a R803K mutation mediates chemotherapy resistance by inducing cellular senescence in small cell lung cancer |
| Fisetin | Lung Cancer | 4 | PM | 30802432 | 📋 | Fisetin suppresses migration, invasion and stem-cell-like phenotype of human non-small cell lung carcinoma cells via attenuation of epithelial to mesenchymal transition |
| Fisetin | Lung Cancer | 5 | PM | 29495431 | 📋 | Evaluation of Anti-Metastatic Potential of the Combination of Fisetin with Paclitaxel on A549 Non-Small Cell Lung Cancer Cells |
| Fisetin | Lung Cancer | 3 | PM | 29467859 | 📋 | Fisetin inhibits the growth and migration in the A549 human lung cancer cell line via the ERK1/2 pathway |
| Fisetin | Lung Cancer | 1 | PM | 28440400 | 📋 | Carnosic acid and fisetin combination therapy enhances inhibition of lung cancer through apoptosis induction |
| Fisetin | Lung Cancer | 2 | PM | 27904686 | 📋 | Fisetin, a dietary phytochemical, overcomes Erlotinib-resistance of lung adenocarcinoma cells through inhibition of MAPK and AKT pathways |
| Fisetin | Lung Cancer | 15 | PM | 26884726 | 📋 | Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells |
| Fisetin | Lung Cancer | 14 | PM | 26797785 | 📋 | Fisetin induces apoptosis and endoplasmic reticulum stress in human non-small cell lung cancer through inhibition of the MAPK signaling pathway |
| Fisetin | Lung Cancer | 12 | PM | 26692948 | 📋 | Fisetin, a dietary bioflavonoid, reverses acquired Cisplatin-resistance of lung adenocarcinoma cells through MAPK/Survivin/Caspase pathway |
| Fisetin | Lung Cancer | 13 | PM | 25381036 | 📋 | Fisetin induces apoptosis in human nonsmall lung cancer cells via a mitochondria-mediated pathway |
| Fisetin | Lung Cancer | 9 | PM | 21618507 | 📋 | Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin |
| Fisetin | Lung Cancer | 11 | PM | 21315788 | 📋 | Fisetin, a novel flavonol attenuates benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice |
| Fisetin | Lung Cancer | 10 | PM | 21069336 | 📋 | Improved antiangiogenic and antitumour activity of the combination of the natural flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma-bearing mice |
| Fisetin | Melanoma | 2 | PM | 30356079 | 📋 | Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models |
| Fisetin | Melanoma | 7 | PM | 26517521 | 📋 | Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma |
| Fisetin | Melanoma | 3 | PM | 26299806 | 📋 | Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells |
| Fisetin | Melanoma | 6 | PM | 25016296 | 📋 | Involvement of ER stress and activation of apoptotic pathways in fisetin induced cytotoxicity in human melanoma |
| Fisetin | Melanoma | 1 | PM | 25000190 | 📋 | Melatonin enhances the anti-tumor effect of fisetin by inhibiting COX-2/iNOS and NF-κB/p300 signaling pathways |
| Fisetin | Melanoma | 4 | PM | 21566577 | 📋 | Fisetin: a natural fist against melanoma? |
| Fisetin | Melanoma | 5 | PM | 21346776 | 📋 | Inhibition of human melanoma cell growth by the dietary flavonoid fisetin is associated with disruption of Wnt/β-catenin signaling and decreased Mitf levels |
| Fisetin | Multiple Myeloma | 1 | PM | 22261340 | 📋 | Activation of reactive oxygen species/AMP activated protein kinase signaling mediates fisetin-induced apoptosis in multiple myeloma U266 cells |
| Fisetin | Nasopharyngeal Cancer | 1 | PM | 24297333 | 📋 | Fisetin inhibits migration, invasion and epithelial-mesenchymal transition of LMP1-positive nasopharyngeal carcinoma cells |
| Fisetin | Oral Cancer | 4 | PM | 33928003 | 📋 | Integrated analysis and identification of nine-gene signature associated to oral squamous cell carcinoma pathogenesis |
| Fisetin | Oral Cancer | 2 | PM | 32158195 | 📋 | Fisetin Modulates Human Oral Squamous Cell Carcinoma Proliferation by Blocking PAK4 Signaling Pathways |
| Fisetin | Oral Cancer | 3 | PM | 30662534 | 📋 | Crosstalk between Fisetin-induced Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma |
| Fisetin | Oral Cancer | 6 | PM | 29312520 | 📋 | Fisetin suppresses malignant proliferation in human oral squamous cell carcinoma through inhibition of Met/Src signaling pathways |
| Fisetin | Oral Cancer | 5 | PM | 29102932 | 📋 | Fisetin Induces Apoptosis of HSC3 Human Oral Cancer Cells Through Endoplasmic Reticulum Stress and Dysfunction of Mitochondria-mediated Signaling Pathways |
| Fisetin | Oral Cancer | 1 | PM | 28181380 | 📋 | Fisetin-induced apoptosis of human oral cancer SCC-4 cells through reactive oxygen species production, endoplasmic reticulum stress, caspase-, and mitochondria-dependent signaling pathways |
| Fisetin | Ovarian Cancer | 6 | PM | 35538559 | 📋 | Fisetin-induced cell death in human ovarian cancer cell lines via zbp1-mediated necroptosis |
| Fisetin | Ovarian Cancer | 5 | PM | 34900143 | 📋 | Apoptosis Induction with Combined Use of Cisplatin and Fisetin in Cisplatin-Resistant Ovarian Cancer Cells (A2780) |
| Fisetin | Ovarian Cancer | 1 | PM | 30378308 | 📋 | [In vitro and in vivo Antitumor Effects of Fisetin and Fisetin Nanopartical on Ovarian Cancer] |
| Fisetin | Ovarian Cancer | 4 | PM | 29544480 | 📋 | Fisetin and polymeric micelles encapsulating fisetin exhibit potent cytotoxic effects towards ovarian cancer cells |
| Fisetin | Ovarian Cancer | 2 | PM | 28598107 | 📋 | [The Antitumor Effects of Fisetin on Ovarian Cancer in vitro and in vivo] |
| Fisetin | Ovarian Cancer | 3 | PM | 28119082 | 📋 | A hydroxylated flavonol, fisetin inhibits the formation of a carcinogenic estrogen metabolite |
| Fisetin | Ovarian Cancer | 7 | PM | 21216935 | 📋 | Anticancer activity of a combination of cisplatin and fisetin in embryonal carcinoma cells and xenograft tumors |
| Fisetin | Pancreatic Cancer | 6 | PM | 35033590 | 📋 | ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer |
| Fisetin | Pancreatic Cancer | 5 | PM | 34821587 | 📋 | Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling |
| Fisetin | Pancreatic Cancer | 1 | PM | 33093461 | 📋 | Fisetin inhibits proliferation of pancreatic adenocarcinoma by inducing DNA damage via RFXAP/KDM4A-dependent histone H3K36 demethylation |
| Fisetin | Pancreatic Cancer | 2 | PM | 30760707 | 📋 | Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways |
| Fisetin | Pancreatic Cancer | 3 | PM | 29848706 | 📋 | Fisetin Enhances the Cytotoxicity of Gemcitabine by Down-regulating ERK-MYC in MiaPaca-2 Human Pancreatic Cancer Cells |
| Fisetin | Pancreatic Cancer | 4 | PM | 19670328 | 📋 | Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB |
| Fisetin | Prostate Cancer | 5 | PM | 34836005 | 📋 | Kaempferol, Myricetin and Fisetin in Prostate and Bladder Cancer: A Systematic Review of the Literature |
| Fisetin | Prostate Cancer | 11 | PM | 27765854 | 📋 | Fisetin Enhances Chemotherapeutic Effect of Cabazitaxel against Human Prostate Cancer Cells |
| Fisetin | Prostate Cancer | 3 | PM | 27335141 | 📋 | Dietary flavonoid fisetin increases abundance of high-molecular-mass hyaluronan conferring resistance to prostate oncogenesis |
| Fisetin | Prostate Cancer | 10 | PM | 26235140 | 📋 | Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells |
| Fisetin | Prostate Cancer | 2 | PM | 22842629 | 📋 | Dietary flavonoid fisetin: a novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management |
| Fisetin | Prostate Cancer | 9 | PM | 21743964 | 📋 | The dietary flavonol fisetin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells |
| Fisetin | Prostate Cancer | 8 | PM | 20574928 | 📋 | Antiproliferative mechanisms of the flavonoids 2,2'-dihydroxychalcone and fisetin in human prostate cancer cells |
| Fisetin | Prostate Cancer | 7 | PM | 20530556 | 📋 | Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells |
| Fisetin | Prostate Cancer | 6 | PM | 19633975 | 📋 | Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells |
| Fisetin | Prostate Cancer | 1 | PM | 18922931 | 📋 | A novel dietary flavonoid fisetin inhibits androgen receptor signaling and tumor growth in athymic nude mice |
| Fisetin | Prostate Cancer | 4 | PM | 18359761 | 📋 | Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells |
| Fisetin | Renal Cell Carcinoma | 2 | PM | 38426151 | 📋 | Fisetin enhances cisplatin sensitivity in renal cell carcinoma via the CDK6/PI3K/Akt/mTOR signaling pathway |
| Fisetin | Renal Cell Carcinoma | 1 | PM | 31438640 | 📋 | Fisetin Suppresses the Proliferation and Metastasis of Renal Cell Carcinoma through Upregulation of MEK/ERK-Targeting CTSS and ADAM9 |
| Fisetin | Retinoblastoma | 1 | PM | 32724364 | 📋 | Fisetin inhibits vascular endothelial growth factor-induced angiogenesis in retinoblastoma cells |
| Fisetin | Skin Cancer | 1 | PM | 30742987 | 📋 | Fisetin loaded binary ethosomes for management of skin cancer by dermal application on UV exposed mice |
| Fisetin | Skin Cancer | 4 | PM | 29049844 | 📋 | Flavonoids inhibit chronically exposed arsenic-induced proliferation and malignant transformation of HaCaT cells |
| Fisetin | Skin Cancer | 3 | PM | 23800058 | 📋 | Fisetin inhibits growth, induces G₂ /M arrest and apoptosis of human epidermoid carcinoma A431 cells: role of mitochondrial membrane potential disruption and consequent caspases activation |
| Fisetin | Testicular Cancer | 1 | PM | 21216935 | 📋 | Anticancer activity of a combination of cisplatin and fisetin in embryonal carcinoma cells and xenograft tumors |
| Fisetin | Uveal Melanoma | 1 | PM | 29383865 | 📋 | Fisetin induces apoptosis through mitochondrial apoptosis pathway in human uveal melanoma cells |
