| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Ellagic Acid | Acute Myeloid Leukemia | 1 | PM | 30838722 | 📋 | Antitumour effects of selected plant polyphenols, gallic acid and ellagic acid, on sensitive and multidrug-resistant leukaemia HL60 cells |
| Ellagic Acid | Bladder Cancer | 6 | PM | 34075841 | 📋 | A prospective observational study on oral administration of Ellagic Acid and Annona Muricata in patients affected by non-muscle invasive bladder cancer not undergoing maintenance after 6-week intravesical prophylaxis |
| Ellagic Acid | Bladder Cancer | 5 | PM | 33922395 | 📋 | Ellagic Acid Resensitizes Gemcitabine-Resistant Bladder Cancer Cells by Inhibiting Epithelial-Mesenchymal Transition and Gemcitabine Transporters |
| Ellagic Acid | Bladder Cancer | 1 | PM | 27879653 | 📋 | Ellagic Acid Inhibits Bladder Cancer Invasiveness and In Vivo Tumor Growth |
| Ellagic Acid | Bladder Cancer | 4 | PM | 23811531 | 📋 | In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells |
| Ellagic Acid | Bladder Cancer | 3 | PM | 23554011 | 📋 | Ellagic acid induces apoptosis in TSGH8301 human bladder cancer cells through the endoplasmic reticulum stress- and mitochondria-dependent signaling pathways |
| Ellagic Acid | Bladder Cancer | 2 | PM | 15868936 | 📋 | Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells |
| Ellagic Acid | Breast Cancer | 14 | PM | 38476024 | 📋 | CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A |
| Ellagic Acid | Breast Cancer | 13 | PM | 38107139 | 📋 | A comprehensive review on Ellagic acid in breast cancer treatment: From cellular effects to molecular mechanisms of action |
| Ellagic Acid | Breast Cancer | 1 | PM | 32429317 | 📋 | Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6 |
| Ellagic Acid | Breast Cancer | 12 | PM | 29197410 | 📋 | Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells |
| Ellagic Acid | Breast Cancer | 8 | PM | 28718725 | 📋 | Ellagic Acid Enhances Apoptotic Sensitivity of Breast Cancer Cells to γ-Radiation |
| Ellagic Acid | Breast Cancer | 7 | PM | 24528038 | 📋 | Ellagic acid exerts anti-proliferation effects via modulation of Tgf-β/Smad3 signaling in MCF-7 breast cancer cells |
| Ellagic Acid | Breast Cancer | 11 | PM | 24222122 | 📋 | Anticancer activity of a hydrogel containing folic acid towards MCF-7 and MDA-MB-231 cells |
| Ellagic Acid | Breast Cancer | 9 | PM | 23791885 | 📋 | MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention |
| Ellagic Acid | Breast Cancer | 10 | PM | 23065001 | 📋 | Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer |
| Ellagic Acid | Breast Cancer | 6 | PM | 22350787 | 📋 | Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer |
| Ellagic Acid | Breast Cancer | 5 | PM | 21768881 | 📋 | Chemoprevention of mammary carcinogenesis by sustained systemic delivery of ellagic acid |
| Ellagic Acid | Breast Cancer | 3 | PM | 20501861 | 📋 | Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism |
| Ellagic Acid | Breast Cancer | 4 | PM | 18444155 | 📋 | Dietary berries and ellagic acid diminish estrogen-mediated mammary tumorigenesis in ACI rats |
| Ellagic Acid | Breast Cancer | 2 | PM | 11506803 | 📋 | Effect of Chemopreventive Agents on DNA Adduction Induced by the Potent Mammary Carcinogen Dibenzo[a,l]pyrene in the Human Breast Cells MCF-7 |
| Ellagic Acid | Cancer | 17 | PM | 38002335 | 📋 | Ellagic Acid and Cancer Hallmarks: Insights from Experimental Evidence |
| Ellagic Acid | Cancer | 16 | PM | 37935292 | 📋 | Discovery of ellagic acid as a competitive inhibitor of Src homology phosphotyrosyl phosphatase 2 (SHP2) for cancer treatment: In vitro and in silico study |
| Ellagic Acid | Cancer | 15 | PM | 37692691 | 📋 | A Review of the Dietary Intake, Bioavailability and Health Benefits of Ellagic Acid (EA) with a Primary Focus on Its Anti-Cancer Properties |
| Ellagic Acid | Cancer | 14 | PM | 37423169 | 📋 | The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art |
| Ellagic Acid | Cancer | 13 | PM | 36607523 | 📋 | Ellagic acid inhibits mitochondrial fission protein Drp-1 and cell proliferation in cancer |
| Ellagic Acid | Cancer | 11 | PM | 35217437 | 📋 | Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment |
| Ellagic Acid | Cancer | 12 | PM | 34846078 | 📋 | Ellagic acid as a potent anti-cancer drug: A comprehensive review on in vitro, in vivo, in silico and drug delivery studies |
| Ellagic Acid | Cancer | 10 | PM | 33669953 | 📋 | Ellagic Acid and Schisandrins: Natural Biaryl Polyphenols with Therapeutic Potential to Overcome Multidrug Resistance in Cancer |
| Ellagic Acid | Cancer | 9 | PM | 33099806 | 📋 | Phytocompounds Curcumin, Quercetin, Indole-3-carbinol, and Resveratrol, modulate Lactate-Pyruvate level along with cytotoxic activity in HeLa Cervical Cancer cells |
| Ellagic Acid | Cancer | 2 | PM | 32905943 | 📋 | Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activities |
| Ellagic Acid | Cancer | 3 | PM | 32410114 | 📋 | Ellagic acid and human cancers: a systems pharmacology and docking study to identify principal hub genes and main mechanisms of action |
| Ellagic Acid | Cancer | 6 | PM | 29066891 | 📋 | Enhanced anticancer activity and oral bioavailability of ellagic acid through encapsulation in biodegradable polymeric nanoparticles |
| Ellagic Acid | Cancer | 5 | PM | 28838842 | 📋 | Ellagic acid antagonizes Bnip3-mediated mitochondrial injury and necrotic cell death of cardiac myocytes |
| Ellagic Acid | Cancer | 4 | PM | 26366074 | 📋 | Investigation of the biological and anti-cancer properties of ellagic acid-encapsulated nano-sized metalla-cages |
| Ellagic Acid | Cancer | 1 | PM | 17046132 | 📋 | The Inhibition of Human Glutathione S-transferases Activity by Plant Polyphenolic Compounds Ellagic Acid and Curcumin |
| Ellagic Acid | Cancer | 8 | PM | 15590271 | 📋 | In vitro anti-proliferative activities of ellagic acid |
| Ellagic Acid | Cancer | 7 | PM | 7644381 | 📋 | The dietary anticancer agent ellagic acid is a potent inhibitor of DNA topoisomerases in vitro |
| Ellagic Acid | Cervical Cancer | 6 | PM | 37894909 | 📋 | Ellagic Acid from Hull Blackberries: Extraction, Purification, and Potential Anticancer Activity |
| Ellagic Acid | Cervical Cancer | 5 | PM | 34726804 | 📋 | Shifting of cell cycle arrest from the S-phase to G2/M phase and downregulation of EGFR expression by phytochemical combinations in HeLa cervical cancer cells |
| Ellagic Acid | Cervical Cancer | 3 | PM | 28454338 | 📋 | Ellagic acid and Annona muricata in the chemoprevention of HPV-related pre-neoplastic lesions of the cervix |
| Ellagic Acid | Cervical Cancer | 2 | PM | 27941714 | 📋 | Inhibition of Cervical Cancer by Promoting IGFBP7 Expression Using Ellagic Acid from Pomegranate Peel |
| Ellagic Acid | Cervical Cancer | 1 | PM | 27261574 | 📋 | Curcumin and Ellagic Acid Synergistically Induce ROS Generation, DNA Damage, p53 Accumulation and Apoptosis in HeLa Cervical Carcinoma Cells |
| Ellagic Acid | Cervical Cancer | 4 | PM | 19863348 | 📋 | Augmentation of radiation-induced apoptosis by ellagic acid |
| Ellagic Acid | Cisplatin Toxicity | 3 | PM | 35990576 | 📋 | Ellagic acid modulates cisplatin toxicity in DMH induced colorectal cancer: Studies on membrane alterations |
| Ellagic Acid | Cisplatin Toxicity | 1 | PM | 30953405 | 📋 | Ellagic acid ameliorates cisplatin induced hepatotoxicity in colon carcinogenesis |
| Ellagic Acid | Cisplatin Toxicity | 4 | PM | 23426532 | 📋 | Ellagic acid protects against cisplatin-induced nephrotoxicity in rats: a dose-dependent study |
| Ellagic Acid | Cisplatin Toxicity | 2 | PM | 17910619 | 📋 | Ellagic acid prevents cisplatin-induced oxidative stress in liver and heart tissue of rats |
| Ellagic Acid | Colon Cancer | 9 | PM | 36847079 | 📋 | Ellagic acid inhibits human colon cancer HCT-116 cells by regulating long noncoding RNAs |
| Ellagic Acid | Colon Cancer | 4 | PM | 36701898 | 📋 | Ellagic acid induces apoptosis and autophagy in colon cancer through the AMPK/mTOR pathway |
| Ellagic Acid | Colon Cancer | 2 | PM | 32468010 | 📋 | Ellagic Acid Induces Cell Cycle Arrest and Apoptosis via the TGF‑β1/Smad3 Signaling Pathway in Human Colon Cancer HCT‑116 Cells |
| Ellagic Acid | Colon Cancer | 5 | PM | 30953405 | 📋 | Ellagic acid ameliorates cisplatin induced hepatotoxicity in colon carcinogenesis |
| Ellagic Acid | Colon Cancer | 11 | PM | 28508835 | 📋 | Beneficial influence of ellagic acid on biochemical indexes associated with experimentally induced colon carcinogenesis |
| Ellagic Acid | Colon Cancer | 1 | PM | 28501702 | 📋 | Brown Adipose Tissue Activation by Rutin Ameliorates Polycystic Ovary Syndrome in Rat |
| Ellagic Acid | Colon Cancer | 3 | PM | 27270323 | 📋 | Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice |
| Ellagic Acid | Colon Cancer | 6 | PM | 25758919 | 📋 | The ellagic acid derivative 4,4'-di-O-methylellagic acid efficiently inhibits colon cancer cell growth through a mechanism involving WNT16 |
| Ellagic Acid | Colon Cancer | 10 | PM | 24281858 | 📋 | Antiproliferative and apoptotic-inducing potential of ellagic acid against 1,2-dimethyl hydrazine-induced colon tumorigenesis in Wistar rats |
| Ellagic Acid | Colon Cancer | 8 | PM | 16848514 | 📋 | Induction of cell death in Caco-2 human colon carcinoma cells by ellagic acid rich fractions from muscadine grapes (Vitis rotundifolia) |
| Ellagic Acid | Colorectal Cancer | 4 | PM | 35990576 | 📋 | Ellagic acid modulates cisplatin toxicity in DMH induced colorectal cancer: Studies on membrane alterations |
| Ellagic Acid | Colorectal Cancer | 3 | PM | 33147777 | 📋 | Unripe Black Raspberry ( Rubus coreanus Miquel) Extract and Its Constitute, Ellagic Acid Induces T Cell Activation and Antitumor Immunity by Blocking PD-1/PD-L1 Interaction |
| Ellagic Acid | Colorectal Cancer | 1 | PM | 28101576 | 📋 | Multiple effects of ellagic acid on human colorectal carcinoma cells identified by gene expression profile analysis |
| Ellagic Acid | Colorectal Cancer | 2 | PM | 23060566 | 📋 | Effects of ellagic acid on chemosensitivity to 5-fluorouracil in colorectal carcinoma cells |
| Ellagic Acid | Endometrial Cancer | 1 | PM | 28467979 | 📋 | Negative Effect of Ellagic Acid on Cytosolic pH Regulation and Glycolytic Flux in Human Endometrial Cancer Cells |
| Ellagic Acid | Esophageal Cancer | 1 | PM | 32374927 | 📋 | Ellagic Acid Induces Esophageal Squamous Cell Carcinoma Cell Apoptosis by Modulating SHP-1/STAT3 Signaling |
| Ellagic Acid | Esophageal Cancer | 2 | PM | 1998940 | 📋 | The effects of ellagic acid and 13-cis-retinoic acid on N-nitrosobenzylmethylamine-induced esophageal tumorigenesis in rats |
| Ellagic Acid | Gastric Cancer | 3 | PM | 37794689 | 📋 | Exploring the mechanism of ellagic acid against gastric cancer based on bioinformatics analysis and network pharmacology |
| Ellagic Acid | Gastric Cancer | 2 | PM | 35179410 | 📋 | The effects of ellagic acid and other pomegranate ( Punica granatum L.) derivatives on human gastric cancer AGS cells |
| Ellagic Acid | Gastric Cancer | 1 | PM | 31835645 | 📋 | Ellagic Acid Inhibits Extracellular Acidity-Induced Invasiveness and Expression of COX1, COX2, Snail, Twist 1, and c-myc in Gastric Carcinoma Cells |
| Ellagic Acid | Glioblastoma | 1 | PM | 28035411 | 📋 | Ellagic acid inhibits human glioblastoma growth in vitro and in vivo |
| Ellagic Acid | Glioblastoma | 2 | PM | 26959625 | 📋 | Ellagic acid inhibits proliferation and induces apoptosis in human glioblastoma cells |
| Ellagic Acid | Glioma | 1 | PM | 35946772 | 📋 | Antitumor activity of irinotecan with ellagic acid in C6 glioma cells |
| Ellagic Acid | Leukemia | 1 | PM | 25636891 | 📋 | Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: Synergism with arabinofuranosylcytosine |
| Ellagic Acid | Liver Cancer | 9 | PM | 38205284 | 📋 | Ellagic acid inhibits tumor growth and potentiates the therapeutic efficacy of sorafenib in hepatocellular carcinoma |
| Ellagic Acid | Liver Cancer | 8 | PM | 37835585 | 📋 | Modulation of the Tumor Microenvironment by Ellagic Acid in Rat Model for Hepatocellular Carcinoma: A Potential Target against Hepatic Cancer Stem Cells |
| Ellagic Acid | Liver Cancer | 7 | PM | 35081125 | 📋 | 1,8 Cineole and Ellagic acid inhibit hepatocarcinogenesis via upregulation of MiR-122 and suppression of TGF-β1, FSCN1, Vimentin, VEGF, and MMP-9 |
| Ellagic Acid | Liver Cancer | 6 | PM | 35034879 | 📋 | Punicalin and ellagic acid from pomegranate peel extract facilitate apoptotic behaviour in the Hela cell line |
| Ellagic Acid | Liver Cancer | 5 | PM | 33862123 | 📋 | Transcriptome analysis of signaling pathways targeted by Ellagic acid in hepatocellular carcinoma cells |
| Ellagic Acid | Liver Cancer | 2 | PM | 33030061 | 📋 | Synergistic Effects of Ellagic Acid and Sorafenib on Hepatocytes and Mitochondria Isolated from a Hepatocellular Carcinoma Rat Model |
| Ellagic Acid | Liver Cancer | 3 | PM | 29479987 | 📋 | Ellagic Acid Holds Promise Against Hepatocellular Carcinoma in an Experimental Model: Mechanisms of Action |
| Ellagic Acid | Liver Cancer | 4 | PM | 29070894 | 📋 | Radiosensitizing effect of ellagic acid on growth of Hepatocellular carcinoma cells: an in vitro study |
| Ellagic Acid | Liver Cancer | 1 | PM | 9149115 | 📋 | Protective Effect of Food Additives on Aflatoxin-Induced Mutagenicity and Hepatocarcinogenicity |
| Ellagic Acid | Lung Cancer | 1 | PM | 32608435 | 📋 | Phenolic Compound Ellagic Acid Inhibits Mitochondrial Respiration and Tumor Growth in Lung Cancer |
| Ellagic Acid | Lung Cancer | 4 | PM | 32525282 | 📋 | Combination effects of ellagic acid with erlotinib in a Ba/F3 cell line expressing EGFR H773_V774 insH mutation |
| Ellagic Acid | Lung Cancer | 3 | PM | 30191764 | 📋 | Inhalable lactoferrin-chondroitin nanocomposites for combined delivery of doxorubicin and ellagic acid to lung carcinoma |
| Ellagic Acid | Lung Cancer | 2 | PM | 1437655 | 📋 | Biodistribution of ellagic acid and dose-related inhibition of lung tumorigenesis in A/J mice |
| Ellagic Acid | Lymphoma | 1 | PM | 26276710 | 📋 | Role of ellagic acid in regulation of apoptosis by modulating novel and atypical PKC in lymphoma bearing mice |
| Ellagic Acid | Lymphoma | 2 | PM | 23111456 | 📋 | Ellagic acid checks lymphoma promotion via regulation of PKC signaling pathway |
| Ellagic Acid | Melanoma | 1 | PM | 32509220 | 📋 | Ellagic Acid Inhibits Cell Proliferation, Migration, and Invasion in Melanoma via EGFR Pathway |
| Ellagic Acid | Neuroblastoma | 2 | PM | 24051122 | 📋 | Ellagic acid induces a dose- and time-dependent depolarization of mitochondria and activation of caspase-9 and -3 in human neuroblastoma cells |
| Ellagic Acid | Neuroblastoma | 1 | PM | 18848760 | 📋 | Effect of ellagic acid on proliferation, cell adhesion and apoptosis in SH-SY5Y human neuroblastoma cells |
| Ellagic Acid | Oral Cancer | 5 | PM | 29109723 | 📋 | Inhibition of Pro-inflammatory and Anti-apoptotic Biomarkers during Experimental Oral Cancer Chemoprevention by Dietary Black Raspberries |
| Ellagic Acid | Oral Cancer | 2 | PM | 23732810 | 📋 | Ellagic acid encapsulated chitosan nanoparticles for drug delivery system in human oral cancer cell line (KB) |
| Ellagic Acid | Oral Cancer | 3 | PM | 23645727 | 📋 | Ellagic Acid, a Dietary Polyphenol, Selectively Cytotoxic to HSC-2 Oral Carcinoma Cells |
| Ellagic Acid | Oral Cancer | 1 | PM | 22485181 | 📋 | Gene expression signature of DMBA-induced hamster buccal pouch carcinomas: modulation by chlorophyllin and ellagic acid |
| Ellagic Acid | Oral Cancer | 4 | PM | 22160170 | 📋 | Ellagic acid coordinately attenuates Wnt/β-catenin and NF-κB signaling pathways to induce intrinsic apoptosis in an animal model of oral oncogenesis |
| Ellagic Acid | Ovarian Cancer | 1 | PM | 32415699 | 📋 | The Anti-Tumorigenic Effect of Ellagic Acid in SKOV-3 Ovarian Cancer Cells Entails Activation of Autophagy-Mediated by Inhibiting Akt and Activating AMPK |
| Ellagic Acid | Ovarian Cancer | 2 | PM | 29173024 | 📋 | Main components of pomegranate, ellagic acid and luteolin, inhibit metastasis of ovarian cancer by down-regulating MMP2 and MMP9 |
| Ellagic Acid | Ovarian Cancer | 3 | PM | 23843871 | 📋 | The inhibitory effect of ellagic Acid on cell growth of ovarian carcinoma cells |
| Ellagic Acid | Pancreatic Cancer | 5 | PM | 35116272 | 📋 | Determining the effect of ellagic acid on the proliferation and migration of pancreatic cancer cell lines |
| Ellagic Acid | Pancreatic Cancer | 4 | PM | 28696100 | 📋 | Thermosensitive Liposomal Codelivery of HSA-Paclitaxel and HSA-Ellagic Acid Complexes for Enhanced Drug Perfusion and Efficacy Against Pancreatic Cancer |
| Ellagic Acid | Pancreatic Cancer | 3 | PM | 28135203 | 📋 | Ellagic acid inhibits the proliferation of human pancreatic carcinoma PANC-1 cells in vitro and in vivo |
| Ellagic Acid | Pancreatic Cancer | 7 | PM | 24127740 | 📋 | Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells |
| Ellagic Acid | Pancreatic Cancer | 6 | PM | 23684930 | 📋 | Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice |
| Ellagic Acid | Pancreatic Cancer | 2 | PM | 18595134 | 📋 | Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells |
| Ellagic Acid | Pancreatic Cancer | 1 | PM | 11787891 | 📋 | Modulation of Radiation-Induced Protein Kinase C Activity by Phenolics |
| Ellagic Acid | Prostate Cancer | 1 | PM | 32705219 | 📋 | MDM2 as a target for ellagic acid‑mediated suppression of prostate cancer cells in vitro |
| Ellagic Acid | Prostate Cancer | 4 | PM | 28169238 | 📋 | Evaluating the effects of ellagic acid on pSTAT3, pAKT, and pERK1/2 signaling pathways in prostate cancer PC3 cells |
| Ellagic Acid | Prostate Cancer | 2 | PM | 25284475 | 📋 | Ellagic acid, a component of pomegranate fruit juice, suppresses androgen-dependent prostate carcinogenesis via induction of apoptosis |
| Ellagic Acid | Prostate Cancer | 10 | PM | 24216999 | 📋 | Effects of ellagic Acid on angiogenic factors in prostate cancer cells |
| Ellagic Acid | Prostate Cancer | 9 | PM | 24085108 | 📋 | Apoptotic markers in a prostate cancer cell line: effect of ellagic acid |
| Ellagic Acid | Prostate Cancer | 8 | PM | 23803044 | 📋 | Ellagic acid inhibits migration and invasion by prostate cancer cell lines |
| Ellagic Acid | Prostate Cancer | 11 | PM | 23710216 | 📋 | Pomegranate Juice Metabolites, Ellagic Acid and Urolithin A, Synergistically Inhibit Androgen-Independent Prostate Cancer Cell Growth via Distinct Effects on Cell Cycle Control and Apoptosis |
| Ellagic Acid | Prostate Cancer | 7 | PM | 23092326 | 📋 | Ellagic acid: cytodifferentiating and antiproliferative effects in human prostatic cancer cell lines |
| Ellagic Acid | Prostate Cancer | 6 | PM | 23066443 | 📋 | Specific pomegranate juice components as potential inhibitors of prostate cancer metastasis |
| Ellagic Acid | Prostate Cancer | 5 | PM | 21803307 | 📋 | Influence of ellagic acid on prostate cancer cell proliferation: a caspase-dependent pathway |
| Ellagic Acid | Prostate Cancer | 3 | PM | 15774240 | 📋 | Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate |
| Ellagic Acid | Thyroid Cancer | 1 | PM | 36773307 | 📋 | Ellagic acid inhibits cell proliferation, migration, and invasion of anaplastic thyroid cancer cells via the Wnt/β-catenin and PI3K/Akt pathways |
