| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Chrysin | Bladder Cancer | 3 | PM | 36093567 | 📋 | Chrysin inhibits the cell viability, induces apoptosis and modulates expression of genes related to epigenetic events in bladder cancer cells |
| Chrysin | Bladder Cancer | 2 | PM | 32789469 | 📋 | Toxicogenetic and antiproliferative effects of chrysin in urinary bladder cancer cells |
| Chrysin | Bladder Cancer | 1 | PM | 29805643 | 📋 | Chrysin Induces Cell Growth Arrest, Apoptosis, and ER Stress and Inhibits the Activation of STAT3 Through the Generation of ROS in Bladder Cancer Cells |
| Chrysin | Bone Cancer | 1 | PM | 35979647 | 📋 | Chrysin sensitizes osteosarcoma cells against TRAIL-induced apoptosis |
| Chrysin | Breast Cancer | 7 | PM | 38110365 | 📋 | Pyrotinib and chrysin synergistically potentiate autophagy in HER2-positive breast cancer |
| Chrysin | Breast Cancer | 6 | PM | 36964888 | 📋 | Synergistic effect of chrysin and radiotherapy against triple-negative breast cancer (TNBC) cell lines |
| Chrysin | Breast Cancer | 5 | PM | 34985375 | 📋 | Chrysin impairs genomic stability by suppressing DNA double-strand break repair in breast cancer cells |
| Chrysin | Breast Cancer | 4 | PM | 32181408 | 📋 | Inhibitory effect of chrysin on estrogen biosynthesis by suppression of enzyme aromatase (CYP19): A systematic review |
| Chrysin | Breast Cancer | 3 | PM | 29890668 | 📋 | Anti-Tumorigenic Activity of Chrysin From Oroxylum indicum via Non-Genotoxic p53 Activation Through the ATM-Chk2 Pathway |
| Chrysin | Breast Cancer | 2 | PM | 29693804 | 📋 | Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells Through hTERT and Cyclin D1 Suppression |
| Chrysin | Breast Cancer | 1 | PM | 27761071 | 📋 | Inhibitory and Cytotoxic Activities of Chrysin on Human Breast Adenocarcinoma Cells by Induction of Apoptosis |
| Chrysin | Cancer | 8 | PM | 37416770 | 📋 | Natural Nrf2 Inhibitors: A Review of Their Potential for Cancer Treatment |
| Chrysin | Cancer | 7 | PM | 36687219 | 📋 | Anti-cancer Activity of Chrysin in Cancer Therapy: a Systematic Review |
| Chrysin | Cancer | 6 | PM | 35543434 | 📋 | Immune Stimulating Outcome of Chrysin and γ-Irradiation via Apoptotic Activation Against Solid Ehrlich Carcinoma Bearing Mice |
| Chrysin | Cancer | 4 | PM | 33858433 | 📋 | Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin |
| Chrysin | Cancer | 3 | PM | 32992587 | 📋 | Broad-Spectrum Preclinical Antitumor Activity of Chrysin: Current Trends and Future Perspectives |
| Chrysin | Cancer | 5 | PM | 32930436 | 📋 | Plant flavone Chrysin as an emerging histone deacetylase inhibitor for prosperous epigenetic-based anticancer therapy |
| Chrysin | Cancer | 2 | PM | 20133051 | 📋 | Chrysin Sensitizes Tumor Necrosis Factor-Alpha-Induced Apoptosis in Human Tumor Cells via Suppression of Nuclear factor-kappaB |
| Chrysin | Cancer | 1 | PM | 19653143 | 📋 | Apigenin, Chrysin, and Luteolin Selectively Inhibit Chymotrypsin-Like and Trypsin-Like Proteasome Catalytic Activities in Tumor Cells |
| Chrysin | Cervical Cancer | 3 | PM | 35844432 | 📋 | Chrysin and Capsaicin induces premature senescence and apoptosis via mitochondrial dysfunction and p53 elevation in Cervical cancer cells |
| Chrysin | Cervical Cancer | 2 | PM | 35096000 | 📋 | Chrysin Modulates Aberrant Epigenetic Variations and Hampers Migratory Behavior of Human Cervical (HeLa) Cells |
| Chrysin | Cervical Cancer | 1 | PM | 31001962 | 📋 | Chrysin Inhibits Proinflammatory Factor-Induced EMT Phenotype and Cancer Stem Cell-Like Features in HeLa Cells by Blocking the NF-κB/Twist Axis |
| Chrysin | Choriocarcinoma | 1 | PM | 30139515 | 📋 | Chrysin Disrupts Intracellular Homeostasis Through Mitochondria-Mediated Cell Death in Human Choriocarcinoma Cells |
| Chrysin | Cisplatin Toxicity | 1 | PM | 36193760 | 📋 | Suppression of cisplatin-induced ovarian injury in rats by chrysin: an experimental study |
| Chrysin | Colon Cancer | 2 | PM | 31646391 | 📋 | Chrysin and Docetaxel Loaded Biodegradable Micelle for Combination Chemotherapy of Cancer Stem Cell |
| Chrysin | Colon Cancer | 1 | PM | 28959334 | 📋 | Anticancer Properties of Chrysin on Colon Cancer Cells, In vitro and In vivo With Modulation of Caspase-3, -9, Bax and Sall4 |
| Chrysin | Colorectal Cancer | 4 | PM | 33625784 | 📋 | Combined effect of chrysin and apigenin on inhibiting the development and progression of colorectal cancer by suppressing the activity of P38-MAPK/AKT pathway |
| Chrysin | Colorectal Cancer | 3 | PM | 33249075 | 📋 | Promising targets of chrysin and daidzein in colorectal cancer: amphiregulin, CXCL1, and MMP-9 |
| Chrysin | Colorectal Cancer | 2 | PM | 32754278 | 📋 | Cartilage Oligomeric Matrix Protein promotes epithelial-mesenchymal transition by interacting with Transgelin in Colorectal Cancer |
| Chrysin | Colorectal Cancer | 1 | PM | 29899208 | 📋 | Chrysin Attenuates Cell Viability of Human Colorectal Cancer Cells Through Autophagy Induction Unlike 5-Fluorouracil/Oxaliplatin |
| Chrysin | Colorectal Cancer | 5 | PM | 26347954 | 📋 | Antiproliferative Activity of New Zealand Propolis and Phenolic Compounds vs Human Colorectal Adenocarcinoma Cells |
| Chrysin | Endometrial Cancer | 1 | PM | 34278450 | 📋 | Chrysin induces autophagy through the inactivation of the ROS‑mediated Akt/mTOR signaling pathway in endometrial cancer |
| Chrysin | Esophageal Cancer | 1 | PM | 33532186 | 📋 | Chrysin serves as a novel inhibitor of DGK α/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC) |
| Chrysin | Gastric Cancer | 6 | PM | 36597606 | 📋 | Chrysin effect against gastric cancer: focus on its molecular mechanisms |
| Chrysin | Gastric Cancer | 4 | PM | 34150620 | 📋 | Chrysin Induced Cell Apoptosis Through H19/let-7a/ COPB2 Axis in Gastric Cancer Cells and Inhibited Tumor Growth |
| Chrysin | Gastric Cancer | 2 | PM | 33240430 | 📋 | Potentiating activities of chrysin in the therapeutic efficacy of 5-fluorouracil in gastric cancer cells |
| Chrysin | Gastric Cancer | 3 | PM | 32368086 | 📋 | Chrysin Induced Cell Apoptosis and Inhibited Invasion Through Regulation of TET1 Expression in Gastric Cancer Cells |
| Chrysin | Gastric Cancer | 5 | PM | 26347954 | 📋 | Antiproliferative Activity of New Zealand Propolis and Phenolic Compounds vs Human Colorectal Adenocarcinoma Cells |
| Chrysin | Gastric Cancer | 1 | PM | 25875631 | 📋 | Chrysin Inhibits Tumor Promoter-Induced MMP-9 Expression by Blocking AP-1 via Suppression of ERK and JNK Pathways in Gastric Cancer Cells |
| Chrysin | Glioblastoma | 2 | PM | 33767729 | 📋 | ceRNA Network Analysis Shows That lncRNA CRNDE Promotes Progression of Glioblastoma Through Sponge mir-9-5p |
| Chrysin | Glioblastoma | 1 | PM | 29662304 | 📋 | Chrysin Suppresses Proliferation, Migration, and Invasion in Glioblastoma Cell Lines via Mediating the ERK/Nrf2 Signaling Pathway |
| Chrysin | Glioblastoma | 3 | PM | 28458011 | 📋 | Chrysin and silibinin sensitize human glioblastoma cells for arsenic trioxide |
| Chrysin | Glioma | 1 | PM | 26537082 | 📋 | Additive Anticancer Effects of Chrysin and Low Dose Cisplatin in Human Malignant Glioma Cell (U87) Proliferation and Evaluation of the Mechanistic Pathway |
| Chrysin | Kidney Cancer | 2 | PM | 27403965 | 📋 | Inhibition of Precancerous Lesions Development in Kidneys by Chrysin via Regulating Hyperproliferation, Inflammation and Apoptosis at Pre Clinical Stage |
| Chrysin | Kidney Cancer | 1 | PM | 23194824 | 📋 | Chrysin Suppresses Renal Carcinogenesis via Amelioration of Hyperproliferation, Oxidative Stress and Inflammation: Plausible Role of NF-κB |
| Chrysin | Liver Cancer | 9 | PM | 35708083 | 📋 | The Combination of Chrysin and Cisplatin Induces Apoptosis in HepG2 through Down-regulation of cFLIP and Active of Caspase |
| Chrysin | Liver Cancer | 8 | PM | 34923234 | 📋 | Chrysin inhibits hepatocellular carcinoma progression through suppressing programmed death ligand 1 expression |
| Chrysin | Liver Cancer | 6 | PM | 33755959 | 📋 | Chrysin inhibits propagation of HeLa cells by attenuating cell survival and inducing apoptotic pathways |
| Chrysin | Liver Cancer | 5 | PM | 33076548 | 📋 | Antineoplastic Activity of Chrysin against Human Hepatocellular Carcinoma: New Insight on GPC3/SULF2 Axis and lncRNA-AF085935 Expression |
| Chrysin | Liver Cancer | 7 | PM | 31708277 | 📋 | Selective toxicity of chrysin on mitochondria isolated from liver of a HCC rat model |
| Chrysin | Liver Cancer | 1 | PM | 31114345 | 📋 | Chrysin Inhibits Sphere Formation in SMMC-7721 Cells via Modulation of SHP-1/STAT3 Signaling Pathway |
| Chrysin | Liver Cancer | 4 | PM | 30377128 | 📋 | [Chrysin Promotes SMMC-7721 Cell Apoptosis by Regulating MAPKs Signaling Pathway] |
| Chrysin | Liver Cancer | 3 | PM | 28320429 | 📋 | Chrysin Inhibited Tumor Glycolysis and Induced Apoptosis in Hepatocellular Carcinoma by Targeting hexokinase-2 |
| Chrysin | Liver Cancer | 2 | PM | 27347080 | 📋 | Chrysin Induces Cell Apoptosis via Activation of the p53/Bcl-2/caspase-9 Pathway in Hepatocellular Carcinoma Cells |
| Chrysin | Lung Cancer | 5 | PM | 38675475 | 📋 | Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer |
| Chrysin | Lung Cancer | 4 | PM | 31551535 | 📋 | Chrysin Enhances Anticancer Drug-Induced Toxicity Mediated by the Reduction of claudin-1 and 11 Expression in a Spheroid Culture Model of Lung Squamous Cell Carcinoma Cells |
| Chrysin | Lung Cancer | 2 | PM | 27151585 | 📋 | Chrysin Increases the Therapeutic Efficacy of Docetaxel and Mitigates Docetaxel-Induced Edema |
| Chrysin | Lung Cancer | 3 | PM | 26922533 | 📋 | Chemopreventive Effect of Chrysin, a Dietary Flavone Against Benzo(a)pyrene Induced Lung Carcinogenesis in Swiss Albino Mice |
| Chrysin | Lung Cancer | 1 | PM | 17266043 | 📋 | Reversal of Inflammation-Associated Dihydrodiol Dehydrogenases (AKR1C1 and AKR1C2) Overexpression and Drug Resistance in Nonsmall Cell Lung Cancer Cells by Wogonin and Chrysin |
| Chrysin | Melanoma | 6 | PM | 37371032 | 📋 | Chrysin-Induced Regression of Angiogenesis via an Induction of DNA Damage Response and Oxidative Stress in In Vitro and In Vivo Models of Melanoma |
| Chrysin | Melanoma | 5 | PM | 35884773 | 📋 | Chrysin Induces Apoptosis and Autophagy in Human Melanoma Cells via the mTOR/S6K Pathway |
| Chrysin | Melanoma | 1 | PM | 35484925 | 📋 | Chrysin Enhances Anti-tumor Immunity Response through IL-12-STAT4 Signal Pathway in B16F10 Melanoma Mouse Model |
| Chrysin | Melanoma | 4 | PM | 32797754 | 📋 | Chrysin inhibits melanoma tumor metastasis via interfering the FOXM1/β-catenin signaling |
| Chrysin | Melanoma | 3 | PM | 30578657 | 📋 | Chrysin Inhibit Human Melanoma A375.S2 Cell Migration and Invasion via Affecting MAPK Signaling and NF-κB Signaling Pathway in Vitro |
| Chrysin | Melanoma | 2 | PM | 29352974 | 📋 | Chrysin, a Natural and Biologically Active Flavonoid Suppresses Tumor Growth of Mouse B16F10 Melanoma Cells: In Vitro and In Vivo Study |
| Chrysin | Oral Cancer | 3 | PM | 36555388 | 📋 | Chrysin Induces Apoptosis via the MAPK Pathway and Regulates ERK/mTOR-Mediated Autophagy in MC-3 Cells |
| Chrysin | Oral Cancer | 2 | PM | 36167320 | 📋 | Effects of Chrysin on Oral Squamous Cell Carcinoma In Vitro |
| Chrysin | Oral Cancer | 1 | PM | 31303615 | 📋 | [Effects of Chrysin on the Apoptosis in Oral Squamous Carcinoma KB Cell Line and the Underlying Mechanisms] |
| Chrysin | Ovarian Cancer | 4 | PM | 37970041 | 📋 | Co-administration of Chrysin and Luteolin with Cisplatin and Topotecan Exhibits a Variable Therapeutic Value in Human Cancer Cells, HeLa |
| Chrysin | Ovarian Cancer | 3 | PM | 31933724 | 📋 | NF-κB/Twist Axis Is Involved in Chysin Inhibition of Ovarian Cancer Stem Cell Features Induced by Co-Treatment of TNF-α and TGF-β |
| Chrysin | Ovarian Cancer | 1 | PM | 28816359 | 📋 | Chrysin Attenuates Progression of Ovarian Cancer Cells by Regulating Signaling Cascades and Mitochondrial Dysfunction |
| Chrysin | Ovarian Cancer | 2 | PM | 27470961 | 📋 | [Effects of Chrysin on Sphere Formation and CK2α Expression of Ovarian Cancer Stem-Like Cells Derived From SKOV3 Cell Line] |
| Chrysin | Pancreatic Cancer | 2 | PM | 36077069 | 📋 | Chrysin-Induced G Protein-Coupled Estrogen Receptor Activation Suppresses Pancreatic Cancer |
| Chrysin | Pancreatic Cancer | 1 | PM | 34673014 | 📋 | Chrysin induces autophagy-dependent ferroptosis to increase chemosensitivity to gemcitabine by targeting CBR1 in pancreatic cancer cells |
| Chrysin | Prostate Cancer | 2 | PM | 36139362 | 📋 | SPHK/HIF-1α Signaling Pathway Has a Critical Role in Chrysin-Induced Anticancer Activity in Hypoxia-Induced PC-3 Cells |
| Chrysin | Prostate Cancer | 1 | PM | 28213961 | 📋 | Chrysin Induces Death of Prostate Cancer Cells by Inducing ROS and ER Stress |
| Chrysin | Uveal Melanoma | 1 | PM | 28105189 | 📋 | Chrysin Induces Cell Apoptosis in Human Uveal Melanoma Cells via Intrinsic Apoptosis |
