| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Beta-Lapachone | Bladder Cancer | 1 | PM | 16614704 | 📋 | beta-lapachone induces growth inhibition and apoptosis in bladder cancer cells by modulation of Bcl-2 family and activation of caspases |
| Beta-Lapachone | Breast Cancer | 2 | PM | 38518601 | 📋 | Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells |
| Beta-Lapachone | Breast Cancer | 1 | PM | 35893874 | 📋 | Synergistic Effect of β-Lapachone and Aminooxyacetic Acid on Central Metabolism in Breast Cancer |
| Beta-Lapachone | Cancer | 3 | PM | 38846085 | 📋 | β-Lapachone promotes the recruitment and polarization of tumor-associated neutrophils (TANs) toward an antitumor (N1) phenotype in NQO1-positive cancers |
| Beta-Lapachone | Cancer | 1 | PM | 18343063 | 📋 | Comparative studies of the effects of Tabebuia avellanedae bark extract and beta-lapachone on the hematopoietic response of tumour-bearing mice |
| Beta-Lapachone | Cancer | 2 | PM | 17192848 | 📋 | Involvement of NO/cGMP signaling in the apoptotic and anti-angiogenic effects of beta-lapachone on endothelial cells in vitro |
| Beta-Lapachone | Colon Cancer | 1 | PM | 14597880 | 📋 | beta-Lapachone-induced apoptosis is associated with activation of caspase-3 and inactivation of NF-kappaB in human colon cancer HCT-116 cells |
| Beta-Lapachone | Colorectal Cancer | 4 | PM | 38218311 | 📋 | β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway |
| Beta-Lapachone | Colorectal Cancer | 3 | PM | 38139333 | 📋 | Artemisia annua L. Polyphenols Enhance the Anticancer Effect of β-Lapachone in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells |
| Beta-Lapachone | Colorectal Cancer | 2 | PM | 37373014 | 📋 | β-Lapachone Exerts Anticancer Effects by Downregulating p53, Lys-Acetylated Proteins, TrkA, p38 MAPK, SOD1, Caspase-2, CD44 and NPM in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells |
| Beta-Lapachone | Colorectal Cancer | 1 | PM | 27923905 | 📋 | β-Lapachone Inhibits Lung Metastasis of Colorectal Cancer by Inducing Apoptosis of CT26 Cells |
| Beta-Lapachone | Head and Neck Cancer | 1 | PM | 36978989 | 📋 | Single-Cell Kinetic Modeling of β-Lapachone Metabolism in Head and Neck Squamous Cell Carcinoma |
| Beta-Lapachone | Leukemia | 1 | PM | 20438329 | 📋 | Beta-lapachone (LAPA) decreases cell viability and telomerase activity in leukemia cells: suppression of telomerase activity by LAPA |
| Beta-Lapachone | Liver Cancer | 1 | PM | 17827686 | 📋 | Induction of Egr-1 is associated with anti-metastatic and anti-invasive ability of beta-lapachone in human hepatocarcinoma cells |
| Beta-Lapachone | Liver Cancer | 2 | PM | 16822200 | 📋 | Beta-lapachone, a quinone isolated from Tabebuia avellanedae, induces apoptosis in HepG2 hepatoma cell line through induction of Bax and activation of caspase |
| Beta-Lapachone | Lung Cancer | 3 | PM | 38604545 | 📋 | β-Lapachone, an NQO1 bioactivatable drug, prevents lung tumorigenesis in mice |
| Beta-Lapachone | Lung Cancer | 1 | PM | 24505400 | 📋 | Sulindac compounds facilitate the cytotoxicity of β-lapachone by up-regulation of NAD(P)H quinone oxidoreductase in human lung cancer cells |
| Beta-Lapachone | Lung Cancer | 2 | PM | 15753997 | 📋 | Growth inhibition of A549 human lung carcinoma cells by beta-lapachone through induction of apoptosis and inhibition of telomerase activity |
| Beta-Lapachone | Melanoma | 1 | PM | 29434949 | 📋 | Carnosic acid, an inducer of NAD(P)H quinone oxidoreductase 1, enhances the cytotoxicity of β-lapachone in melanoma cell lines |
| Beta-Lapachone | Melanoma | 2 | PM | 26718788 | 📋 | β-lapachone suppresses the proliferation of human malignant melanoma cells by targeting specificity protein 1 |
| Beta-Lapachone | Oral Cancer | 1 | PM | 30071298 | 📋 | β-Lapachone and its iodine derivatives cause cell cycle arrest at G 2/M phase and reactive oxygen species-mediated apoptosis in human oral squamous cell carcinoma cells |
| Beta-Lapachone | Oral Cancer | 2 | PM | 25891355 | 📋 | Downregulation of Sp1 is involved in β-lapachone-induced cell cycle arrest and apoptosis in oral squamous cell carcinoma |
| Beta-Lapachone | Pancreatic Cancer | 1 | PM | 35490325 | 📋 | β-lapachone: a promising anticancer agent with a unique NQO1 specific apoptosis in pancreatic cancer |
| Beta-Lapachone | Prostate Cancer | 1 | PM | 15829436 | 📋 | Down-regulation of cyclooxygenase-2 and telomerase activity by beta-lapachone in human prostate carcinoma cells |
| Beta-Lapachone | Prostate Cancer | 2 | PM | 12689523 | 📋 | Suppression of human prostate cancer cell growth by beta-lapachone via down-regulation of pRB phosphorylation and induction of Cdk inhibitor p21(WAF1/CIP1) |
