| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Apple | Breast Cancer | 2 | PM | 32064624 | 📋 | Phytochemical profiles, antioxidant, and antiproliferative activities of four red-fleshed apple varieties in China |
| Apple | Breast Cancer | 1 | PM | 31540221 | 📋 | Apple Peel Flavonoid Fraction 4 Suppresses Breast Cancer Cell Growth by Cytostatic and Cytotoxic Mechanisms |
| Apple | Breast Cancer | 13 | PM | 26416794 | 📋 | Evaluation of antioxidative and antitumor activities of extracted flavonoids from Pink Lady apples in human colon and breast cancer cell lines |
| Apple | Breast Cancer | 14 | PM | 26284516 | 📋 | Inhibition of Breast Cancer Cell Proliferation and In Vitro Tumorigenesis by a New Red Apple Cultivar |
| Apple | Breast Cancer | 3 | PM | 22924395 | 📋 | In vitro and in vivo antimammary tumor activities and mechanisms of the apple total triterpenoids |
| Apple | Breast Cancer | 5 | PM | 19072049 | 📋 | Fresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley rat |
| Apple | Breast Cancer | 11 | PM | 19053381 | 📋 | Apple phytochemical extracts inhibit proliferation of estrogen-dependent and estrogen-independent human breast cancer cells through cell cycle modulation |
| Apple | Breast Cancer | 10 | PM | 18828600 | 📋 | Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities |
| Apple | Breast Cancer | 9 | PM | 17373813 | 📋 | Effect of Selected Phytochemicals and Apple Extracts on NF-kappaB Activation in Human Breast Cancer MCF-7 Cells |
| Apple | Breast Cancer | 4 | PM | 15769178 | 📋 | Apples prevent mammary tumors in rats |
| Apple | Cancer | 2 | PM | 28911529 | 📋 | An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids |
| Apple | Cancer | 3 | PM | 27000627 | 📋 | Apple intake and cancer risk: a systematic review and meta-analysis of observational studies |
| Apple | Cancer | 1 | PM | 26633321 | 📋 | Dihydrochalcone Compounds Isolated from Crabapple Leaves Showed Anticancer Effects on Human Cancer Cell Lines |
| Apple | Cancer | 6 | PM | 18855307 | 📋 | Cancer chemopreventive potential of apples, apple juice, and apple components |
| Apple | Cancer | 4 | PM | 16091428 | 📋 | Does an apple a day keep the oncologist away? |
| Apple | Colon Cancer | 7 | PM | 29156563 | 📋 | WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations |
| Apple | Colon Cancer | 10 | PM | 27272442 | 📋 | Antioxidant, Antibacterial, and Antiproliferative Activities of Free and Bound Phenolics from Peel and Flesh of Fuji Apple |
| Apple | Colon Cancer | 9 | PM | 26416794 | 📋 | Evaluation of antioxidative and antitumor activities of extracted flavonoids from Pink Lady apples in human colon and breast cancer cell lines |
| Apple | Colon Cancer | 11 | PM | 25493015 | 📋 | Chemopreventive effect of apple and berry fruits against colon cancer |
| Apple | Colon Cancer | 4 | PM | 25412264 | 📋 | Apple polysaccharide reduces NF-Kb mediated colitis-associated colon carcinogenesis |
| Apple | Colon Cancer | 5 | PM | 22924395 | 📋 | In vitro and in vivo antimammary tumor activities and mechanisms of the apple total triterpenoids |
| Apple | Colon Cancer | 3 | PM | 20652274 | 📋 | Apple juice intervention modulates expression of ARE-dependent genes in rat colon and liver |
| Apple | Colon Cancer | 8 | PM | 19666002 | 📋 | Apple procyanidins activate apoptotic signaling pathway in human colon adenocarcinoma cells by a lipid-raft independent mechanism |
| Apple | Colorectal Cancer | 6 | PM | 36513476 | 📋 | The potential chemo-preventive roles of Malus domestica against the risk of colorectal cancer: A suggestive insight into clinical application |
| Apple | Colorectal Cancer | 10 | PM | 33921048 | 📋 | Azoxymethane-Induced Colorectal Cancer Mice Treated with a Polyphenol-Rich Apple Extract Show Less Neoplastic Lesions and Signs of Cachexia |
| Apple | Colorectal Cancer | 2 | PM | 31887919 | 📋 | Apple polysaccharide protects ICR mice against colitis associated colorectal cancer through the regulation of microbial dysbiosis |
| Apple | Colorectal Cancer | 3 | PM | 31058564 | 📋 | Chemopreventive Potential of Apple Pulp Callus Against Colorectal Cancer Cell Proliferation and Tumorigenesis |
| Apple | Colorectal Cancer | 1 | PM | 28389232 | 📋 | An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer |
| Apple | Colorectal Cancer | 5 | PM | 19926998 | 📋 | Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables |
| Apple | Colorectal Cancer | 4 | PM | 19476292 | 📋 | An apple a day may hold colorectal cancer at bay: recent evidence from a case-control study |
| Apple | Colorectal Cancer | 8 | PM | 18262392 | 📋 | Histone-deacetylase inhibition and butyrate formation: Fecal slurry incubations with apple pectin and apple juice extracts |
| Apple | Esophageal Cancer | 1 | PM | 18683822 | 📋 | Procyanidin effects on oesophageal adenocarcinoma cells strongly depend on flavan-3-ol degree of polymerization |
| Apple | Gastric Cancer | 1 | PM | 31475373 | 📋 | Phenolic compounds present in fruit extracts of Malus spp. show antioxidative and pro-apoptotic effects on human gastric cancer cell lines |
| Apple | Gastric Cancer | 2 | PM | 15138614 | 📋 | Induction of apoptosis by three types of procyanidin isolated from apple (Rosaceae Malus pumila) in human stomach cancer KATO III cells |
| Apple | Liver Cancer | 5 | PM | 25256427 | 📋 | Flavonoid-enriched apple fraction AF4 induces cell cycle arrest, DNA topoisomerase II inhibition, and apoptosis in human liver cancer HepG2 cells |
| Apple | Liver Cancer | 4 | PM | 22924395 | 📋 | In vitro and in vivo antimammary tumor activities and mechanisms of the apple total triterpenoids |
| Apple | Liver Cancer | 3 | PM | 20652274 | 📋 | Apple juice intervention modulates expression of ARE-dependent genes in rat colon and liver |
| Apple | Liver Cancer | 6 | PM | 18828600 | 📋 | Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities |
| Apple | Liver Cancer | 7 | PM | 12537430 | 📋 | Antioxidant activity of apple peels |
| Apple | Skin Cancer | 1 | PM | 32242497 | 📋 | Apple Extract ( Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin |
| Apple | Tongue Cancer | 1 | PM | 26062009 | 📋 | Antioxidant activity of apple extract protects against rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide |
