Substance | Condition | Seq | Src | PMID | Dtl | Title |
Paeoniflorin | Alzheimer's Disease | 5 | PM | 38027768 | 📋 | Network pharmacology and in vivo studies reveal the neuroprotective effects of paeoniflorin on Alzheimer's disease |
Paeoniflorin | Alzheimer's Disease | 4 | PM | 37448137 | 📋 | Paeoniflorin suppresses neuronal ferroptosis to improve the cognitive behaviors in Alzheimer's disease mice |
Paeoniflorin | Alzheimer's Disease | 3 | PM | 36902268 | 📋 | Paeoniflorin Attenuates Lipopolysaccharide-Induced Cognitive Dysfunction by Inhibition of Amyloidogenesis in Mice |
Paeoniflorin | Alzheimer's Disease | 2 | PM | 35449815 | 📋 | Multiple Roles of Paeoniflorin in Alzheimer's Disease |
Paeoniflorin | Alzheimer's Disease | 1 | PM | 33282122 | 📋 | Paeoniflorin ameliorates Aβ-stimulated neuroinflammation via regulation of NF-κB signaling pathway and Aβ degradation in C6 glial cells |
Paeoniflorin | Cerebral Ischemia | 1 | PM | 28752625 | 📋 | Reduction of Ischemic Brain Edema by Combined Use of Paeoniflorin and Astragaloside IV via Down-Regulating Connexin 43 |
Paeoniflorin | Cerebral Ischemia-Reperfusion | 1 | PM | 35462929 | 📋 | Preclinical Evidence of Paeoniflorin Effectiveness for the Management of Cerebral Ischemia/Reperfusion Injury: A Systematic Review and Meta-Analysis |
Paeoniflorin | Cognitive Disorders | 3 | PM | 35230626 | 📋 | Paeoniflorin ameliorates cognitive impairment in Parkinson's disease via JNK/p53 signaling |
Paeoniflorin | Cognitive Disorders | 1 | PM | 31115613 | 📋 | Paeoniflorin attenuates impairment of spatial learning and hippocampal long-term potentiation in mice subjected to chronic unpredictable mild stress |
Paeoniflorin | Cognitive Disorders | 2 | PM | 29572012 | 📋 | Effects of paeoniflorin on neurobehavior, oxidative stress, brain insulin signaling, and synaptic alterations in intracerebroventricular streptozotocin-induced cognitive impairment in mice |
Paeoniflorin | Depression | 8 | PM | 37315645 | 📋 | Identification of paeoniflorin from Paeonia lactiflora pall. As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice |
Paeoniflorin | Depression | 7 | PM | 35770096 | 📋 | Integrating Metabolomics and Network Analysis for Exploring the Mechanism Underlying the Antidepressant Activity of Paeoniflorin in Rats With CUMS-Induced Depression |
Paeoniflorin | Depression | 6 | PM | 35185541 | 📋 | Network Pharmacology-Based and Experimental Identification of the Effects of Paeoniflorin on Major Depressive Disorder |
Paeoniflorin | Depression | 3 | PM | 35143936 | 📋 | Efficacy of paeoniflorin on models of depression: A systematic review and meta-analysis of rodent studies |
Paeoniflorin | Depression | 1 | PM | 34334273 | 📋 | Paeoniflorin: A neuroprotective monoterpenoid glycoside with promising anti-depressive properties |
Paeoniflorin | Depression | 4 | PM | 33025508 | 📋 | Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway |
Paeoniflorin | Depression | 5 | PM | 32733578 | 📋 | Antidepression and Prokinetic Effects of Paeoniflorin on Rats in the Forced Swimming Test via Polypharmacology |
Paeoniflorin | Depression | 2 | PM | 31115613 | 📋 | Paeoniflorin attenuates impairment of spatial learning and hippocampal long-term potentiation in mice subjected to chronic unpredictable mild stress |
Paeoniflorin | Diabetic Encephalopathy | 1 | PM | 28322909 | 📋 | Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats |
Paeoniflorin | Glioblastoma | 2 | PM | 35957872 | 📋 | Paeoniflorin Inhibits EMT and Angiogenesis in Human Glioblastoma via K63-Linked C-Met Polyubiquitination-Dependent Autophagic Degradation |
Paeoniflorin | Glioblastoma | 1 | PM | 29740218 | 📋 | Paeoniflorin inhibits glioblastoma growth in vivo and in vitro: a role for the Triad3A-dependent ubiquitin proteasome pathway in TLR4 degradation |
Paeoniflorin | Glioma | 1 | PM | 36618071 | 📋 | Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells |
Paeoniflorin | Ischemic Stroke | 2 | PM | 38178130 | 📋 | Combination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke |
Paeoniflorin | Ischemic Stroke | 1 | PM | 35938509 | 📋 | Combination of paeoniflorin and calycosin-7-glucoside alleviates ischaemic stroke injury via the PI3K/AKT signalling pathway |
Paeoniflorin | Schizophrenia | 1 | PM | 35571896 | 📋 | Paeoniflorin Rescued MK-801-Induced Schizophrenia-Like Behaviors in Mice via Oxidative Stress Pathway |