| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Curcumin | Aging Brain | 10 | PM | 38796662 | 📋 | Curcumin protects against aging-related stress and dysfunction through autophagy activation in rat brain |
| Curcumin | Aging Brain | 9 | PM | 38687459 | 📋 | Curcumin attenuates brain aging by reducing apoptosis and oxidative stress |
| Curcumin | Aging Brain | 8 | PM | 34443381 | 📋 | Curcumin as Prospective Anti-Aging Natural Compound: Focus on Brain |
| Curcumin | Aging Brain | 7 | PM | 33133809 | 📋 | Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain |
| Curcumin | Aging Brain | 6 | PM | 33029285 | 📋 | Curcumin and hesperetin attenuate D-galactose-induced brain senescence in vitro and in vivo |
| Curcumin | Aging Brain | 5 | PM | 21253949 | 📋 | Protective Effect of Curcumin (Curcuma Longa) Against D-galactose-induced Senescence in Mice |
| Curcumin | Aging Brain | 4 | PM | 20403421 | 📋 | Effect of Dimethylsulphoxide and Curcumin on Protein Carbonyls and Reactive Oxygen Species of Cerebral Hemispheres of Mice as a Function of Age |
| Curcumin | Aging Brain | 2 | PM | 19020987 | 📋 | Curcumin Counteracts the Aluminium-Induced Ageing-Related Alterations in Oxidative Stress, Na+, K+ ATPase and Protein Kinase C in Adult and Old Rat Brain Regions |
| Curcumin | Aging Brain | 1 | PM | 18362141 | 📋 | Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus |
| Curcumin | Aging Brain | 3 | PM | 16802111 | 📋 | Neuroprotective and Anti-Ageing Effects of Curcumin in Aged Rat Brain Regions |
| Curcumin | Alzheimer's Disease | 82 | PM | 38791161 | 📋 | Curcumin Improves Neurogenesis in Alzheimer's Disease Mice via the Upregulation of Wnt/β-Catenin and BDNF |
| Curcumin | Alzheimer's Disease | 81 | PM | 38616356 | 📋 | Neuroprotective and anti-inflammatory effects of curcumin in Alzheimer's disease: Targeting neuroinflammation strategies |
| Curcumin | Alzheimer's Disease | 80 | PM | 38265680 | 📋 | Therapeutic potential of curcumin on the cognitive decline in animal models of Alzheimer's disease: a systematic review and meta-analysis |
| Curcumin | Alzheimer's Disease | 79 | PM | 38257133 | 📋 | Curcumin Mitigates the High-Fat High-Sugar Diet-Induced Impairment of Spatial Memory, Hepatic Metabolism, and the Alteration of the Gut Microbiome in Alzheimer's Disease-Induced (3xTg-AD) Mice |
| Curcumin | Alzheimer's Disease | 78 | PM | 37989445 | 📋 | Curcumin alleviates Alzheimer's disease by inhibiting inflammatory response, oxidative stress and activating the AMPK pathway |
| Curcumin | Alzheimer's Disease | 77 | PM | 37566247 | 📋 | Effect of Curcumin on Cognitive Behavior and Pathological Characteristics of the Hippocampus in Mice with Inherent Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 75 | PM | 37239093 | 📋 | Effect of Curcumin and Coenzyme Q10 Alone and in Combination on Learning and Memory in an Animal Model of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 73 | PM | 36856916 | 📋 | Protective effects of curcumin and Ginkgo biloba extract combination on a new model of Alzheimer's disease |
| Curcumin | Alzheimer's Disease | 72 | PM | 36652025 | 📋 | Network pharmacology and bioinformatics approach reveals the therapeutic mechanism of action of curcumin in Alzheimer disease |
| Curcumin | Alzheimer's Disease | 71 | PM | 36105064 | 📋 | Curcumin prevents Alzheimer's disease progression by upregulating JMJD3 |
| Curcumin | Alzheimer's Disease | 70 | PM | 36077082 | 📋 | Combined Treatment with Curcumin and Ferulic Acid Suppressed the Aβ-Induced Neurotoxicity More than Curcumin and Ferulic Acid Alone |
| Curcumin | Alzheimer's Disease | 69 | PM | 36069210 | 📋 | Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems |
| Curcumin | Alzheimer's Disease | 68 | PM | 36042609 | 📋 | A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease |
| Curcumin | Alzheimer's Disease | 67 | PM | 35963200 | 📋 | Protective and anti-oxidative effects of curcumin and resveratrol on Aβ-oligomer-induced damage in the SH-SY5Y cell line |
| Curcumin | Alzheimer's Disease | 66 | PM | 35662729 | 📋 | Curcumin as a Holistic Treatment for Tau Pathology |
| Curcumin | Alzheimer's Disease | 65 | PM | 35294663 | 📋 | Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease |
| Curcumin | Alzheimer's Disease | 64 | PM | 35178203 | 📋 | Improvement of cognitive deficit of curcumin on scopolamine-induced Alzheimer's disease models |
| Curcumin | Alzheimer's Disease | 63 | PM | 35176983 | 📋 | A new perspective on the treatment of Alzheimer's disease and sleep deprivation-related conse-quences: Curcumin |
| Curcumin | Alzheimer's Disease | 60 | PM | 35069976 | 📋 | A New Perspective on the Treatment of Alzheimer's Disease and Sleep Deprivation-Related Consequences: Can Curcumin Help? |
| Curcumin | Alzheimer's Disease | 30 | PM | 35035682 | 📋 | Curcumin slows the progression of Alzheimer's disease by modulating mitochondrial stress responses via JMJD3-H3K27me3-BDNF axis |
| Curcumin | Alzheimer's Disease | 29 | PM | 34997713 | 📋 | Curcumin ameliorates lipid metabolic disorder and cognitive dysfunction via the ABCA1 transmembrane transport system in APP/PS1 double transgenic mice |
| Curcumin | Alzheimer's Disease | 62 | PM | 34405526 | 📋 | Curcumin improves memory deficits by inhibiting HMGB1-RAGE/TLR4-NF-κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus |
| Curcumin | Alzheimer's Disease | 61 | PM | 34401962 | 📋 | Curcumin Alleviates Aβ 42-Induced Neuronal Metabolic Dysfunction via the Thrb/SIRT3 Axis and Improves Cognition in APP TG Mice |
| Curcumin | Alzheimer's Disease | 59 | PM | 34208692 | 📋 | Action Mechanisms of Curcumin in Alzheimer's Disease and Its Brain Targeted Delivery |
| Curcumin | Alzheimer's Disease | 58 | PM | 34070220 | 📋 | Curcumin Attenuated Neurotoxicity in Sporadic Animal Model of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 57 | PM | 33557949 | 📋 | Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer's amyloidosis |
| Curcumin | Alzheimer's Disease | 56 | PM | 33375513 | 📋 | Curcumin and Its Derivatives as Theranostic Agents in Alzheimer's Disease: The Implication of Nanotechnology |
| Curcumin | Alzheimer's Disease | 55 | PM | 33237490 | 📋 | Effects of Curcumin and Boric Acid Against Neurodegenerative Damage Induced by Amyloid Beta (1-42) |
| Curcumin | Alzheimer's Disease | 54 | PM | 33062432 | 📋 | Explicating anti-amyloidogenic role of curcumin and piperine via amyloid beta (A β) explicit pathway: recovery and reversal paradigm effects |
| Curcumin | Alzheimer's Disease | 53 | PM | 33029254 | 📋 | Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 52 | PM | 32528227 | 📋 | Therapeutic Potential of Vitamin D and Curcumin in an In Vitro Model of Alzheimer Disease |
| Curcumin | Alzheimer's Disease | 42 | PM | 32448977 | 📋 | Potentiation of anti-Alzheimer Activity of Curcumin by Probiotic Lactobacillus Rhamnosus UBLR-58 Against Scopolamine-Induced Memory Impairment in Mice |
| Curcumin | Alzheimer's Disease | 1 | PM | 32175381 | 📋 | Protective Effects of Curcumin Against Neuroinflammation Induced by Aβ25-35 in Primary Rat Microglia: Modulation of High-Mobility Group Box 1, Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products Expression |
| Curcumin | Alzheimer's Disease | 2 | PM | 32080784 | 📋 | Synergic Effects of Berberine and Curcumin on Improving Cognitive Function in an Alzheimer's Disease Mouse Model |
| Curcumin | Alzheimer's Disease | 16 | PM | 31754658 | 📋 | Curcumin Downregulates GSK3 and Cdk5 in Scopolamine-Induced Alzheimer's Disease Rats Abrogating Aβ 40/42 and Tau Hyperphosphorylation |
| Curcumin | Alzheimer's Disease | 3 | PM | 31507403 | 📋 | Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay |
| Curcumin | Alzheimer's Disease | 22 | PM | 30951849 | 📋 | Curcumin Restores Innate Immune Alzheimer's Disease Risk Gene Expression to Ameliorate Alzheimer Pathogenesis |
| Curcumin | Alzheimer's Disease | 48 | PM | 29894862 | 📋 | Phytochemicals Inhibit the Immunosuppressive Functions of Myeloid-Derived Suppressor Cells (MDSC): Impact on Cancer and Age-Related Chronic Inflammatory Disorders |
| Curcumin | Alzheimer's Disease | 4 | PM | 29614668 | 📋 | A Study of a Supplement Containing Huperzine A and Curcumin in Dementia Patients and Individuals With Mild Cognitive Impairment |
| Curcumin | Alzheimer's Disease | 10 | PM | 28527659 | 📋 | Curcumin Administration Suppress Acetylcholinesterase Gene Expression in Cadmium Treated Rats |
| Curcumin | Alzheimer's Disease | 50 | PM | 28527218 | 📋 | The Mechanisms of Action of Curcumin in Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 20 | PM | 27466310 | 📋 | Curcumin Ameliorates Insulin Signalling Pathway in Brain of Alzheimer's Disease Transgenic Mice |
| Curcumin | Alzheimer's Disease | 28 | PM | 27388114 | 📋 | Amelioration of Scopolamine-Induced Amnesia by Phosphatidylserine and Curcumin in the Day-Old Chick |
| Curcumin | Alzheimer's Disease | 13 | PM | 27060945 | 📋 | Antioxidative and Neuroprotective Effects of Curcumin in an Alzheimer's Disease Rat Model Co-Treated With Intracerebroventricular Streptozotocin and Subcutaneous D-Galactose |
| Curcumin | Alzheimer's Disease | 18 | PM | 26923403 | 📋 | Curcumin Improves Tau-Induced Neuronal Dysfunction of Nematodes |
| Curcumin | Alzheimer's Disease | 36 | PM | 26824354 | 📋 | Curcumin Ameliorates the Reduction Effect of PGE2 on Fibrillar β-Amyloid Peptide (1-42)-Induced Microglial Phagocytosis Through the Inhibition of EP2-PKA Signaling in N9 Microglial Cells |
| Curcumin | Alzheimer's Disease | 24 | PM | 26638997 | 📋 | Downstream Modulation of Extrinsic Apoptotic Pathway in Streptozotocin-Induced Alzheimer's Dementia in Rats: Erythropoietin Versus Curcumin |
| Curcumin | Alzheimer's Disease | 47 | PM | 26618861 | 📋 | Neuronal Uptake and Neuroprotective Properties of Curcumin-Loaded Nanoparticles on SK-N-SH Cell Line: Role of Poly(lactide-co-glycolide) Polymeric Matrix Composition |
| Curcumin | Alzheimer's Disease | 32 | PM | 26529184 | 📋 | Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation Pathway |
| Curcumin | Alzheimer's Disease | 31 | PM | 26487830 | 📋 | Curcumin and Apigenin - Novel and Promising Therapeutics Against Chronic Neuroinflammation in Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 7 | PM | 26053510 | 📋 | Protection of Curcumin Against Amyloid-β-Induced Cell Damage and Death Involves the Prevention From NMDA Receptor-Mediated Intracellular Ca2+ Elevation |
| Curcumin | Alzheimer's Disease | 25 | PM | 26035833 | 📋 | Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice |
| Curcumin | Alzheimer's Disease | 41 | PM | 25818332 | 📋 | Curcumin Inhibits Aβ-induced Microglial Inflammatory Responses in Vitro: Involvement of ERK1/2 and p38 Signaling Pathways |
| Curcumin | Alzheimer's Disease | 33 | PM | 25776887 | 📋 | Curcumin Binding to Beta Amyloid: A Computational Study |
| Curcumin | Alzheimer's Disease | 76 | PM | 24035895 | 📋 | Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons |
| Curcumin | Alzheimer's Disease | 74 | PM | 21939756 | 📋 | Natural substances and Alzheimer's disease: from preclinical studies to evidence based medicine |
| Curcumin | Alzheimer's Disease | 45 | PM | 20963814 | 📋 | Curcuminoids Rescue Long-Term Potentiation Impaired by Amyloid Peptide in Rat Hippocampal Slices |
| Curcumin | Alzheimer's Disease | 37 | PM | 20840842 | 📋 | Potential Therapeutic Effects of Curcumin: Relationship to Microtubule-Associated Proteins 2 in Aβ1-42 Insult |
| Curcumin | Alzheimer's Disease | 34 | PM | 20727383 | 📋 | The Inhibitory Effects of Different Curcuminoids on β-Amyloid Protein, β-Amyloid Precursor Protein and β-Site Amyloid Precursor Protein Cleaving Enzyme 1 in swAPP HEK293 Cells |
| Curcumin | Alzheimer's Disease | 38 | PM | 20638958 | 📋 | Potential Protection of Curcumin Against Intracellular Amyloid Beta-Induced Toxicity in Cultured Rat Prefrontal Cortical Neurons |
| Curcumin | Alzheimer's Disease | 14 | PM | 20622013 | 📋 | Curcumin Decreases Amyloid-Beta Peptide Levels by Attenuating the Maturation of Amyloid-Beta Precursor Protein |
| Curcumin | Alzheimer's Disease | 26 | PM | 20538041 | 📋 | Curcuminoids Enhance Memory in an Amyloid-Infused Rat Model of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 39 | PM | 20413894 | 📋 | PPARgamma Agonist Curcumin Reduces the Amyloid-Beta-Stimulated Inflammatory Responses in Primary Astrocytes |
| Curcumin | Alzheimer's Disease | 49 | PM | 19966973 | 📋 | The Effect of Curcumin (Turmeric) on Alzheimer's Disease: An Overview |
| Curcumin | Alzheimer's Disease | 51 | PM | 19715544 | 📋 | Optimized Turmeric Extracts Have Potent Anti-Amyloidogenic Effects |
| Curcumin | Alzheimer's Disease | 6 | PM | 19433889 | 📋 | 1alpha,25-dihydroxyvitamin D3 Interacts With Curcuminoids to Stimulate Amyloid-Beta Clearance by Macrophages of Alzheimer's Disease Patients |
| Curcumin | Alzheimer's Disease | 11 | PM | 19329286 | 📋 | Amelioration of Cognitive Deficits and Neurodegeneration by Curcumin in Rat Model of Sporadic Dementia of Alzheimer's Type (SDAT) |
| Curcumin | Alzheimer's Disease | 27 | PM | 19027755 | 📋 | Grape Seed Polyphenols and Curcumin Reduce Genomic Instability Events in a Transgenic Mouse Model for Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 17 | PM | 18701050 | 📋 | Curcumin Improves Learning and Memory Ability and Its Neuroprotective Mechanism in Mice |
| Curcumin | Alzheimer's Disease | 46 | PM | 18695518 | 📋 | Epigallocatechin-3-gallate and Curcumin Suppress Amyloid Beta-Induced Beta-Site APP Cleaving enzyme-1 Upregulation |
| Curcumin | Alzheimer's Disease | 40 | PM | 18573304 | 📋 | Curcumin Protected PC12 Cells Against Beta-Amyloid-Induced Toxicity Through the Inhibition of Oxidative Damage and Tau Hyperphosphorylation |
| Curcumin | Alzheimer's Disease | 15 | PM | 18417733 | 📋 | Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 35 | PM | 17996023 | 📋 | Curcumin Binds to the Alpha-Helical Intermediate and to the Amyloid Form of Prion Protein - A New Mechanism for the Inhibition of PrP(Sc) Accumulation |
| Curcumin | Alzheimer's Disease | 23 | PM | 17472706 | 📋 | Curcumin Labels Amyloid Pathology in Vivo, Disrupts Existing Plaques, and Partially Restores Distorted Neurites in an Alzheimer Mouse Model |
| Curcumin | Alzheimer's Disease | 5 | PM | 16988474 | 📋 | Curcuminoids Enhance Amyloid-Beta Uptake by Macrophages of Alzheimer's Disease Patients |
| Curcumin | Alzheimer's Disease | 8 | PM | 15590663 | 📋 | Curcumin Inhibits Formation of Amyloid Beta Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo |
| Curcumin | Alzheimer's Disease | 19 | PM | 15569263 | 📋 | Curcumin, the Active Constituent of Turmeric, Inhibits Amyloid Peptide-Induced Cytochemokine Gene Expression and CCR5-mediated Chemotaxis of THP-1 Monocytes by Modulating Early Growth response-1 Transcription Factor |
| Curcumin | Alzheimer's Disease | 43 | PM | 15345806 | 📋 | Curcumin Interaction With Copper and Iron Suggests One Possible Mechanism of Action in Alzheimer's Disease Animal Models |
| Curcumin | Alzheimer's Disease | 12 | PM | 14994335 | 📋 | Curcumin Has Potent Anti-Amyloidogenic Effects for Alzheimer's Beta-Amyloid Fibrils in Vitro |
| Curcumin | Alzheimer's Disease | 21 | PM | 11755008 | 📋 | Phenolic Anti-Inflammatory Antioxidant Reversal of Abeta-induced Cognitive Deficits and Neuropathology |
| Curcumin | Alzheimer's Disease | 9 | PM | 11606625 | 📋 | The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse |
| Curcumin | Alzheimer's Disease | 44 | PM | 11297823 | 📋 | Curcuminoids From Curcuma Longa L. (Zingiberaceae) That Protect PC12 Rat Pheochromocytoma and Normal Human Umbilical Vein Endothelial Cells From betaA(1-42) Insult |
| Curcumin | Bipolar Disorder | 1 | PM | 28135888 | 📋 | Curcumin for Neuropsychiatric Disorders: A Review of in Vitro, Animal and Human Studies |
| Curcumin | Brain Edema | 5 | PM | 34630953 | 📋 | Evaluation of the protective effect of curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats |
| Curcumin | Brain Edema | 4 | PM | 27979493 | 📋 | Curcumin Attenuates Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice |
| Curcumin | Brain Edema | 2 | PM | 26686249 | 📋 | Curcumin by Down-Regulating NF-kB and Elevating Nrf2, Reduces Brain Edema and Neurological Dysfunction After Cerebral I/R |
| Curcumin | Brain Edema | 1 | PM | 26119880 | 📋 | Curcumin Attenuates Brain Edema in Mice With Intracerebral Hemorrhage Through Inhibition of AQP4 and AQP9 Expression |
| Curcumin | Brain Edema | 3 | PM | 14723822 | 📋 | [Protective Effect and Mechanism of Pretreatment With Curcumin on Infectious Brain Edema in Rats] |
| Curcumin | Brain Inflammation | 13 | PM | 35080289 | 📋 | Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway |
| Curcumin | Brain Inflammation | 2 | PM | 32502596 | 📋 | Curcumin Alleviates Neuroinflammation, Enhances Hippocampal Neurogenesis, and Improves Spatial Memory After Traumatic Brain Injury |
| Curcumin | Brain Inflammation | 19 | PM | 32225104 | 📋 | The Emerging Role of Curcumin in the Modulation of TLR-4 Signaling Pathway: Focus on Neuroprotective and Anti-Rheumatic Properties |
| Curcumin | Brain Inflammation | 1 | PM | 32175381 | 📋 | Protective Effects of Curcumin Against Neuroinflammation Induced by Aβ25-35 in Primary Rat Microglia: Modulation of High-Mobility Group Box 1, Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products Expression |
| Curcumin | Brain Inflammation | 18 | PM | 27979493 | 📋 | Curcumin Attenuates Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice |
| Curcumin | Brain Inflammation | 3 | PM | 27853890 | 📋 | Neuroprotective Potential of Curcumin in Combination With Piperine Against 6-hydroxy Dopamine Induced Motor Deficit and Neurochemical Alterations in Rats |
| Curcumin | Brain Inflammation | 5 | PM | 27026486 | 📋 | Curcumin Reduces Brain-Infiltrating T Lymphocytes After Intracerebral Hemorrhage in Mice |
| Curcumin | Brain Inflammation | 4 | PM | 26828892 | 📋 | Neuroprotective Activity of Curcumin in Combination With Piperine Against Quinolinic Acid Induced Neurodegeneration in Rats |
| Curcumin | Brain Inflammation | 9 | PM | 26639783 | 📋 | Curcumin Pretreatment Attenuates Inflammation and Mitochondrial Dysfunction in Experimental Stroke: The Possible Role of Sirt1 Signaling |
| Curcumin | Brain Inflammation | 7 | PM | 26190183 | 📋 | Curcumin Attenuates Inflammatory Response and Cognitive Deficits in Experimental Model of Chronic Epilepsy |
| Curcumin | Brain Inflammation | 16 | PM | 26047311 | 📋 | Microglial HO-1 Induction by Curcumin Provides Antioxidant, Antineuroinflammatory, and Glioprotective Effects |
| Curcumin | Brain Inflammation | 8 | PM | 25869755 | 📋 | Pretreatment With Curcumin Attenuates Anxiety While Strengthens Memory Performance After One Short Stress Experience in Male Rats |
| Curcumin | Brain Inflammation | 11 | PM | 24669820 | 📋 | Curcumin Attenuates Acute Inflammatory Injury by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway in Experimental Traumatic Brain Injury |
| Curcumin | Brain Inflammation | 10 | PM | 23932920 | 📋 | Curcumin Pretreatment Attenuates Brain Lesion Size and Improves Neurological Function Following Traumatic Brain Injury in the Rat |
| Curcumin | Brain Inflammation | 15 | PM | 20413894 | 📋 | PPARgamma Agonist Curcumin Reduces the Amyloid-Beta-Stimulated Inflammatory Responses in Primary Astrocytes |
| Curcumin | Brain Inflammation | 6 | PM | 18417733 | 📋 | Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease |
| Curcumin | Brain Inflammation | 12 | PM | 17883952 | 📋 | Curcumin Attenuates the Release of Pro-Inflammatory Cytokines in Lipopolysaccharide-Stimulated BV2 Microglia |
| Curcumin | Brain Inflammation | 14 | PM | 15733321 | 📋 | Astrocyte Production of the Chemokine Macrophage Inflammatory protein-2 Is Inhibited by the Spice Principle Curcumin at the Level of Gene Transcription |
| Curcumin | Brain Inflammation | 17 | PM | 14634121 | 📋 | Curcumin Suppresses Janus kinase-STAT Inflammatory Signaling Through Activation of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 in Brain Microglia |
| Curcumin | Brain Injury | 1 | PM | 33396688 | 📋 | Curcumin Prevents Cerebellar Hypoplasia and Restores the Behavior in Hyperbilirubinemic Gunn Rat by a Pleiotropic Effect on the Molecular Effectors of Brain Damage |
| Curcumin | Brain Injury | 18 | PM | 20963814 | 📋 | Curcuminoids Rescue Long-Term Potentiation Impaired by Amyloid Peptide in Rat Hippocampal Slices |
| Curcumin | Brain Injury | 3 | PM | 20816821 | 📋 | A Pyrazole Curcumin Derivative Restores Membrane Homeostasis Disrupted After Brain Trauma |
| Curcumin | Brain Injury | 12 | PM | 20719539 | 📋 | Effect of Combined Treatment With Curcumin and Candesartan on Ischemic Brain Damage in Mice |
| Curcumin | Brain Injury | 8 | PM | 16770732 | 📋 | Immediate and Delayed Treatments With Curcumin Prevents Forebrain Ischemia-Induced Neuronal Damage and Oxidative Insult in the Rat Hippocampus |
| Curcumin | Brain Injury | 16 | PM | 15569404 | 📋 | Curcumin Protects Mitochondria From Oxidative Damage and Attenuates Apoptosis in Cortical Neurons |
| Curcumin | Brain Tumor | 7 | PM | 35178355 | 📋 | Curcumin in Combination with Other Adjunct Therapies for Brain Tumor Treatment: Existing Knowledge and Blueprint for Future Research |
| Curcumin | Brain Tumor | 6 | PM | 34408780 | 📋 | Curcumin Inhibits HGF-Induced EMT by Regulating c-MET-Dependent PI3K/Akt/mTOR Signaling Pathways in Meningioma |
| Curcumin | Brain Tumor | 1 | PM | 24975030 | 📋 | Artemisinin and Curcumin Inhibit Drosophila Brain Tumor, Prolong Life Span, and Restore Locomotor Activity |
| Curcumin | Brain Tumor | 3 | PM | 23192708 | 📋 | Curcumin Inhibits Telomerase and Induces Telomere Shortening and Apoptosis in Brain Tumour Cells |
| Curcumin | Brain Tumor | 5 | PM | 21903608 | 📋 | Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways |
| Curcumin | Brain Tumor | 4 | PM | 19368804 | 📋 | Curcumin Blocks Brain Tumor Formation |
| Curcumin | Brain Tumor | 2 | PM | 16193380 | 📋 | Inhibition of Cellular Proliferation and Induction of Apoptosis by Curcumin in Human Malignant Astrocytoma Cell Lines |
| Curcumin | Cerebral Hypoperfusion | 1 | PM | 33548579 | 📋 | Curcumin protects against cognitive impairments in a rat model of chronic cerebral hypoperfusion combined with diabetes mellitus by suppressing neuroinflammation, apoptosis, and pyroptosis |
| Curcumin | Cerebral Hypoxia | 4 | PM | 32830149 | 📋 | Curcumin targets vascular endothelial growth factor via activating the PI3K/Akt signaling pathway and improves brain hypoxic-ischemic injury in neonatal rats |
| Curcumin | Cerebral Hypoxia | 1 | PM | 25867253 | 📋 | Curcumin Inhibits Apoptosis and Brain Edema Induced by Hypoxia-Hypercapnia Brain Damage in Rat Models |
| Curcumin | Cerebral Hypoxia | 3 | PM | 24975470 | 📋 | Curcumin Protects Neurons Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury Through Activation of Peroxisome Proliferator-Activated Receptor-γ Function |
| Curcumin | Cerebral Hypoxia | 2 | PM | 18461445 | 📋 | Potential Protection of Curcumin Against Hypoxia-Induced Decreases in beta-III Tubulin Content in Rat Prefrontal Cortical Neurons |
| Curcumin | Cerebral Ischemia | 5 | PM | 37580934 | 📋 | Effects of curcumin on memory, hippocampal acetylcholine level and neuroapoptosis in repeated cerebral ischemia rat model |
| Curcumin | Cerebral Ischemia | 4 | PM | 35559238 | 📋 | Mechanisms Underlying Curcumin-Induced Neuroprotection in Cerebral Ischemia |
| Curcumin | Cerebral Ischemia | 3 | PM | 34251185 | 📋 | Neuroprotective Effects of Curcumin in Cerebral Ischemia: Cellular and Molecular Mechanisms |
| Curcumin | Cerebral Ischemia | 2 | PM | 33160958 | 📋 | Curcumin promotes neurogenesis of hippocampal dentate gyrus via Wnt/β-catenin signal pathway following cerebral ischemia in mice |
| Curcumin | Cerebral Ischemia | 26 | PM | 32830149 | 📋 | Curcumin targets vascular endothelial growth factor via activating the PI3K/Akt signaling pathway and improves brain hypoxic-ischemic injury in neonatal rats |
| Curcumin | Cerebral Ischemia | 24 | PM | 32436614 | 📋 | Curcumin Alleviates OGD/R-induced PC12 Cell Damage via Repressing CCL3 and Inactivating TLR4/MyD88/MAPK/NF-κB to Suppress Inflammation and Apoptosis |
| Curcumin | Cerebral Ischemia | 19 | PM | 28053883 | 📋 | Curcumin Reverses Neurochemical, Histological and Immuno-Histochemical Alterations in the Model of Global Brain Ischemia |
| Curcumin | Cerebral Ischemia | 1 | PM | 27026486 | 📋 | Curcumin Reduces Brain-Infiltrating T Lymphocytes After Intracerebral Hemorrhage in Mice |
| Curcumin | Cerebral Ischemia | 6 | PM | 26755923 | 📋 | Curcumin Attenuates the Middle Cerebral Artery Occlusion-Induced Reduction in γ-Enolase Expression in an Animal Model |
| Curcumin | Cerebral Ischemia | 21 | PM | 20719539 | 📋 | Effect of Combined Treatment With Curcumin and Candesartan on Ischemic Brain Damage in Mice |
| Curcumin | Cerebral Ischemia | 18 | PM | 19445907 | 📋 | Curcumin Upregulates Transcription Factor Nrf2, HO-1 Expression and Protects Rat Brains Against Focal Ischemia |
| Curcumin | Cerebral Ischemia | 9 | PM | 19397204 | 📋 | [Effects of Curcumin on Malondialdehyde and C-Fos Protein in Hypoxia Ischemia Brain Tissue in Rats] |
| Curcumin | Cerebral Ischemia | 12 | PM | 18640105 | 📋 | Neuroprotective Effect of Curcumin on Transient Focal Cerebral Ischemia in Rats |
| Curcumin | Cerebral Ischemia | 7 | PM | 18611416 | 📋 | Dose Dependence and Therapeutic Window for the Neuroprotective Effects of Curcumin in Thromboembolic Model of Rat |
| Curcumin | Cerebral Ischemia | 15 | PM | 16770732 | 📋 | Immediate and Delayed Treatments With Curcumin Prevents Forebrain Ischemia-Induced Neuronal Damage and Oxidative Insult in the Rat Hippocampus |
| Curcumin | Cerebral Ischemia | 25 | PM | 16075466 | 📋 | Neuroprotective Mechanisms of Curcumin Against Cerebral Ischemia-Induced Neuronal Apoptosis and Behavioral Deficits |
| Curcumin | Cerebral Ischemia | 16 | PM | 12220971 | 📋 | Protective Effects of Curcumin Against Ischaemia/Reperfusion Insult in Rat Forebrain |
| Curcumin | Cerebral Ischemia-Reperfusion | 18 | PM | 37795892 | 📋 | Curcumin in vitro Neuroprotective Effects Are Mediated by p62/keap-1/Nrf2 and PI3K/AKT Signaling Pathway and Autophagy Inhibition |
| Curcumin | Cerebral Ischemia-Reperfusion | 17 | PM | 37200685 | 📋 | Protective Effect of Curcumin on CA1 Region of Hippocampus in Rat Model of Ischemia/ Reperfusion Injury: |
| Curcumin | Cerebral Ischemia-Reperfusion | 16 | PM | 36996692 | 📋 | Curcumin protects against cerebral ischemia-reperfusion injury in rats by attenuating oxidative stress and inflammation: A meta-analysis and mechanism exploration |
| Curcumin | Cerebral Ischemia-Reperfusion | 13 | PM | 35594387 | 📋 | Curcumin inhibits cerebral ischaemia-reperfusion injury and cell apoptosis in rats through the ERK-CHOP-caspase-11 pathway |
| Curcumin | Cerebral Ischemia-Reperfusion | 15 | PM | 34109908 | 📋 | Curcumin Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting NLRP1-dependent Neuronal Pyroptosis |
| Curcumin | Cerebral Ischemia-Reperfusion | 14 | PM | 33618616 | 📋 | The protective effects of curcumin in cerebral ischemia and reperfusion injury through PKC-θ signaling |
| Curcumin | Cerebral Ischemia-Reperfusion | 12 | PM | 29243061 | 📋 | Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation |
| Curcumin | Cerebral Ischemia-Reperfusion | 9 | PM | 27320251 | 📋 | Curcumin Protects Against Stroke and Increases Levels of Notch Intracellular Domain |
| Curcumin | Cerebral Ischemia-Reperfusion | 5 | PM | 26686249 | 📋 | Curcumin by Down-Regulating NF-kB and Elevating Nrf2, Reduces Brain Edema and Neurological Dysfunction After Cerebral I/R |
| Curcumin | Cerebral Ischemia-Reperfusion | 11 | PM | 26639783 | 📋 | Curcumin Pretreatment Attenuates Inflammation and Mitochondrial Dysfunction in Experimental Stroke: The Possible Role of Sirt1 Signaling |
| Curcumin | Cerebral Ischemia-Reperfusion | 10 | PM | 26628981 | 📋 | Curcumin Protects Against Cerebral Ischemia-Reperfusion Injury by Activating JAK2/STAT3 Signaling Pathway in Rats |
| Curcumin | Cerebral Ischemia-Reperfusion | 3 | PM | 26415414 | 📋 | [Effect of Curcumin on Cerebral Ischemia-reperfusion Injury in Rats] |
| Curcumin | Cerebral Ischemia-Reperfusion | 4 | PM | 21179765 | 📋 | [The Relationship Between the Effects of Curcumin on Cerebral Ischemia/Reperfusion Injury and Immediately Genic Expressions of Fos, Jun and NF-kappaB in Hippocampal CA1 Area and Its Significance in Gerbils] |
| Curcumin | Cerebral Ischemia-Reperfusion | 8 | PM | 19774461 | 📋 | Curcumin Improves Outcomes and Attenuates Focal Cerebral Ischemic Injury via Antiapoptotic Mechanisms in Rats |
| Curcumin | Cerebral Ischemia-Reperfusion | 2 | PM | 19726347 | 📋 | [Effects of Curcumin on the Expression of Nuclear factor-kappaB and Intercellular Adhesion Molecular 1 in Rats With Cerebral Ischemia-Reperfusion Injury] |
| Curcumin | Cerebral Ischemia-Reperfusion | 1 | PM | 18204970 | 📋 | Anti-ischemic Effect of Curcumin in Rat Brain |
| Curcumin | Cerebral Ischemia-Reperfusion | 7 | PM | 17303117 | 📋 | Neuroprotective Effect of Curcumin on Focal Cerebral Ischemic Rats by Preventing Blood-Brain Barrier Damage |
| Curcumin | Cerebral Ischemia-Reperfusion | 6 | PM | 14672754 | 📋 | Neuroprotective Effect of Curcumin in Middle Cerebral Artery Occlusion Induced Focal Cerebral Ischemia in Rats |
| Curcumin | Cognitive Disorders | 22 | PM | 37566247 | 📋 | Effect of Curcumin on Cognitive Behavior and Pathological Characteristics of the Hippocampus in Mice with Inherent Alzheimer's Disease |
| Curcumin | Cognitive Disorders | 21 | PM | 37009141 | 📋 | The effect of curcumin on blood pressure and cognitive impairment in spontaneously hypertensive rats |
| Curcumin | Cognitive Disorders | 20 | PM | 36197595 | 📋 | Roles of Curcumin on Cognitive Impairment Induced by a Mixture of Heavy Metals |
| Curcumin | Cognitive Disorders | 19 | PM | 36094051 | 📋 | The effects of curcumin in learning and memory impairment associated with hypothyroidism in juvenile rats: the role of nitric oxide, oxidative stress, and brain-derived neurotrophic factor |
| Curcumin | Cognitive Disorders | 18 | PM | 35178203 | 📋 | Improvement of cognitive deficit of curcumin on scopolamine-induced Alzheimer's disease models |
| Curcumin | Cognitive Disorders | 17 | PM | 34401962 | 📋 | Curcumin Alleviates Aβ 42-Induced Neuronal Metabolic Dysfunction via the Thrb/SIRT3 Axis and Improves Cognition in APP TG Mice |
| Curcumin | Cognitive Disorders | 16 | PM | 33946356 | 📋 | Curcuma Longa, the "Golden Spice" to Counteract Neuroinflammaging and Cognitive Decline-What Have We Learned and What Needs to Be Done |
| Curcumin | Cognitive Disorders | 15 | PM | 33907454 | 📋 | Curcumin Alleviates Chronic Pain and Improves Cognitive Impairment via Enhancing Hippocampal Neurogenesis in Sciatic Nerve Constriction Rats |
| Curcumin | Cognitive Disorders | 14 | PM | 33849031 | 📋 | Curcumin Reduces Neuroinflammation and Improves the Impairments of Anesthetics on Learning and Memory by Regulating the Expression of miR-181a-5p |
| Curcumin | Cognitive Disorders | 13 | PM | 33748578 | 📋 | Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice |
| Curcumin | Cognitive Disorders | 12 | PM | 33548579 | 📋 | Curcumin protects against cognitive impairments in a rat model of chronic cerebral hypoperfusion combined with diabetes mellitus by suppressing neuroinflammation, apoptosis, and pyroptosis |
| Curcumin | Cognitive Disorders | 10 | PM | 32761362 | 📋 | Curcumin prevents cognitive deficits in the bile duct ligated rats |
| Curcumin | Cognitive Disorders | 11 | PM | 32502596 | 📋 | Curcumin Alleviates Neuroinflammation, Enhances Hippocampal Neurogenesis, and Improves Spatial Memory After Traumatic Brain Injury |
| Curcumin | Cognitive Disorders | 9 | PM | 28224377 | 📋 | Curcumin Attenuates Surgery-Induced Cognitive Dysfunction in Aged Mice |
| Curcumin | Cognitive Disorders | 1 | PM | 26274972 | 📋 | Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions |
| Curcumin | Cognitive Disorders | 8 | PM | 26190183 | 📋 | Curcumin Attenuates Inflammatory Response and Cognitive Deficits in Experimental Model of Chronic Epilepsy |
| Curcumin | Cognitive Disorders | 7 | PM | 25550171 | 📋 | Curcumin Boosts DHA in the Brain: Implications for the Prevention of Anxiety Disorders |
| Curcumin | Cognitive Disorders | 6 | PM | 23099054 | 📋 | Piperine Potentiates the Protective Effects of Curcumin Against Chronic Unpredictable Stress-Induced Cognitive Impairment and Oxidative Damage in Mice |
| Curcumin | Cognitive Disorders | 5 | PM | 22262262 | 📋 | Protective Role of Curcumin on Colchicine-Induced Cognitive Dysfunction and Oxidative Stress in Rats |
| Curcumin | Cognitive Disorders | 4 | PM | 20667451 | 📋 | Curcumin Ameliorates Cognitive Dysfunction and Oxidative Damage in Phenobarbitone and Carbamazepine Administered Rats |
| Curcumin | Cognitive Disorders | 3 | PM | 19765566 | 📋 | Curcumin Is Protective Against Phenytoin-Induced Cognitive Impairment and Oxidative Stress in Rats |
| Curcumin | Cognitive Disorders | 2 | PM | 19540859 | 📋 | Curcumin Reverses Impaired Cognition and Neuronal Plasticity Induced by Chronic Stress |
| Curcumin | Cognitive Performance | 2 | PM | 33097947 | 📋 | Evaluation of Cognitive Performance following Fish-Oil and Curcumin Supplementation in Middle-Aged and Older Adults with Overweight or Obesity |
| Curcumin | Cognitive Performance | 1 | PM | 26019804 | 📋 | Interaction Between the Antioxidant Activity of Curcumin and Cholinergic System on Memory Retention in Adult Male Wistar Rats |
| Curcumin | Depression | 34 | PM | 37506423 | 📋 | The effect of curcumin on reserpine-induced depression-like behaviour in rats |
| Curcumin | Depression | 33 | PM | 37490124 | 📋 | Mechanistic insights into the anti-depressant effect of curcumin based on network pharmacology and experimental validation |
| Curcumin | Depression | 31 | PM | 35786408 | 📋 | Synergistic effects of Lacticaseibacillus rhamnosus GG, glutamine, and curcumin on chronic unpredictable mild stress-induced depression in a mouse model |
| Curcumin | Depression | 30 | PM | 35642797 | 📋 | Curcumin mitigates lipopolysaccharide-induced anxiety/depression-like behaviors, blood-brain barrier dysfunction and brain edema by decreasing cerebral oxidative stress in male rats |
| Curcumin | Depression | 29 | PM | 35129813 | 📋 | Potential Role of Curcumin for the Treatment of Major Depressive Disorder |
| Curcumin | Depression | 20 | PM | 34950248 | 📋 | Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1 α/FNDC5/BDNF Pathway |
| Curcumin | Depression | 17 | PM | 34636389 | 📋 | Prophylactic treatment of curcumin in a rat model of depression by attenuating hippocampal synaptic loss |
| Curcumin | Depression | 28 | PM | 34409523 | 📋 | Therapeutic Potential of Curcumin in Reversing the Depression and Associated Pseudodementia via Modulating Stress Hormone, Hippocampal Neurotransmitters, and BDNF Levels in Rats |
| Curcumin | Depression | 27 | PM | 34331697 | 📋 | Effects of Curcumin on Depression and Anxiety: A Narrative Review of the Recent Clinical Data |
| Curcumin | Depression | 26 | PM | 33673739 | 📋 | A systematic review of the antidepressant effects of curcumin: Beyond monoamines theory |
| Curcumin | Depression | 25 | PM | 33589676 | 📋 | Creation of a gene expression portrait of depression and its application for identifying potential treatments |
| Curcumin | Depression | 24 | PM | 33329109 | 📋 | Curcumin in Depression: Potential Mechanisms of Action and Current Evidence-A Narrative Review |
| Curcumin | Depression | 23 | PM | 33161033 | 📋 | Adaptogenic Effects of Curcumin on Depression Induced by Moderate and Unpredictable Chronic Stress in Mice |
| Curcumin | Depression | 22 | PM | 33098686 | 📋 | Neuromodulatory effect of curcumin on catecholamine systems and inflammatory cytokines in ovariectomized female rats |
| Curcumin | Depression | 21 | PM | 33014280 | 📋 | Curcumin Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors via Restoring Changes in Oxidative Stress and the Activation of Nrf2 Signaling Pathway in Rats |
| Curcumin | Depression | 19 | PM | 31680089 | 📋 | Curcumin Lessens Unpredictable Chronic Mild Stress-Induced Depression and Memory Deficits by Modulating Oxidative Stress and Cholinergic Activity |
| Curcumin | Depression | 16 | PM | 30666189 | 📋 | Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats |
| Curcumin | Depression | 14 | PM | 30551030 | 📋 | Curcumin Relieves Depressive-Like Behaviors via Inhibition of the NLRP3 Inflammasome and Kynurenine Pathway in Rats Suffering From Chronic Unpredictable Mild Stress |
| Curcumin | Depression | 32 | PM | 30268794 | 📋 | Antidepressant-like effect of salidroside and curcumin on the immunoreactivity of rats subjected to a chronic mild stress model |
| Curcumin | Depression | 3 | PM | 29327213 | 📋 | Add-on Treatment With Curcumin Has Antidepressive Effects in Thai Patients With Major Depression: Results of a Randomized Double-Blind Placebo-Controlled Study |
| Curcumin | Depression | 9 | PM | 28167853 | 📋 | Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats |
| Curcumin | Depression | 2 | PM | 26610378 | 📋 | The Role of Curcumin Administration in Patients With Major Depressive Disorder: Mini Meta-Analysis of Clinical Trials |
| Curcumin | Depression | 4 | PM | 26066335 | 📋 | Chronic Supplementation of Curcumin Enhances the Efficacy of Antidepressants in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Pilot Study |
| Curcumin | Depression | 6 | PM | 25523883 | 📋 | Curcumin and Major Depression: A Randomised, Double-Blind, Placebo-Controlled Trial Investigating the Potential of Peripheral Biomarkers to Predict Treatment Response and Antidepressant Mechanisms of Change |
| Curcumin | Depression | 8 | PM | 25091591 | 📋 | Investigation of the Efficacy of Adjunctive Therapy With Bioavailability-Boosted Curcuminoids in Major Depressive Disorder |
| Curcumin | Depression | 7 | PM | 25046624 | 📋 | Curcumin for the Treatment of Major Depression: A Randomised, Double-Blind, Placebo Controlled Study |
| Curcumin | Depression | 10 | PM | 24297305 | 📋 | Chronic Curcumin Treatment Normalizes Depression-Like Behaviors in Mice With Mononeuropathy: Involvement of Supraspinal Serotonergic System and GABAA Receptor |
| Curcumin | Depression | 5 | PM | 23832433 | 📋 | Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial |
| Curcumin | Depression | 12 | PM | 21928724 | 📋 | Evaluation of Antidepressant Like Activity of Curcumin and Its Combination With Fluoxetine and Imipramine: An Acute and Chronic Study |
| Curcumin | Depression | 18 | PM | 19882093 | 📋 | Potentials of Curcumin as an Antidepressant |
| Curcumin | Depression | 1 | PM | 19000708 | 📋 | Anti-depressant Like Effect of Curcumin and Its Combination With Piperine in Unpredictable Chronic Stress-Induced Behavioral, Biochemical and Neurochemical Changes |
| Curcumin | Depression | 13 | PM | 18766332 | 📋 | Antidepressant Activity of Curcumin: Involvement of Serotonin and Dopamine System |
| Curcumin | Depression | 11 | PM | 16171853 | 📋 | Antidepressant Effects of Curcumin in the Forced Swim Test and Olfactory Bulbectomy Models of Depression in Rats |
| Curcumin | Depression | 15 | PM | 15987635 | 📋 | The Effects of Curcumin on Depressive-Like Behaviors in Mice |
| Curcumin | Diabetic Encephalopathy | 10 | PM | 36221434 | 📋 | Curcumin protects PC12 cells from a high glucose-induced inflammatory response by regulating the miR-218-5p/TLR4 axis |
| Curcumin | Diabetic Encephalopathy | 9 | PM | 33602334 | 📋 | Curcumin and its analog alleviate diabetes-induced damages by regulating inflammation and oxidative stress in brain of diabetic rats |
| Curcumin | Diabetic Encephalopathy | 1 | PM | 32375323 | 📋 | Exercise and Curcumin in Combination Improves Cognitive Function and Attenuates ER Stress in Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 8 | PM | 26274972 | 📋 | Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions |
| Curcumin | Diabetic Encephalopathy | 5 | PM | 20637830 | 📋 | Role of Curcumin in the Prevention of Cholinergic Mediated Cortical Dysfunctions in Streptozotocin-Induced Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 4 | PM | 20513244 | 📋 | Curcumin Modulates Dopaminergic Receptor, CREB and Phospholipase C Gene Expression in the Cerebral Cortex and Cerebellum of Streptozotocin Induced Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 7 | PM | 19804785 | 📋 | Neuroprotective Role of Curcumin in the Cerebellum of Streptozotocin-Induced Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 2 | PM | 19234767 | 📋 | Curcumin Ameliorates Impaired insulin/IGF Signalling and Memory Deficit in a Streptozotocin-Treated Rat Model |
| Curcumin | Diabetic Encephalopathy | 6 | PM | 19031318 | 📋 | Curcuminoids Modulates Oxidative Damage and Mitochondrial Dysfunction in Diabetic Rat Brain |
| Curcumin | Diabetic Encephalopathy | 3 | PM | 17822693 | 📋 | Curcumin Attenuates Diabetic Encephalopathy in Rats: Behavioral and Biochemical Evidences |
| Curcumin | Encephalitis | 2 | PM | 24780919 | 📋 | Antioxidants: Potential Antiviral Agents for Japanese Encephalitis Virus Infection |
| Curcumin | Encephalitis | 3 | PM | 19434500 | 📋 | Curcumin Protects Neuronal Cells From Japanese Encephalitis Virus-Mediated Cell Death and Also Inhibits Infective Viral Particle Formation by Dysregulation of Ubiquitin-Proteasome System |
| Curcumin | Encephalitis | 1 | PM | 19000058 | 📋 | Oxidative Stress and Hippocampus in a Low-Grade Hepatic Encephalopathy Model: Protective Effects of Curcumin |
| Curcumin | Encephalomyelitis | 1 | PM | 12055272 | 📋 | Curcumin Inhibits Experimental Allergic Encephalomyelitis by Blocking IL-12 Signaling Through Janus kinase-STAT Pathway in T Lymphocytes |
| Curcumin | Glioblastoma | 17 | PM | 36714540 | 📋 | Combined treatments with AZD5363, AZD8542, curcumin or resveratrol induce death of human glioblastoma cells by suppressing the PI3K/AKT and SHH signaling pathways |
| Curcumin | Glioblastoma | 32 | PM | 35446963 | 📋 | Interaction of curcumin with glioblastoma cells via high and low linear energy transfer radiation therapy inducing radiosensitization effects |
| Curcumin | Glioblastoma | 31 | PM | 34234410 | 📋 | Study on the Inhibitory Effect of Curcumin on GBM and Its Potential Mechanism |
| Curcumin | Glioblastoma | 30 | PM | 33813391 | 📋 | Demethoxycurcumin Suppresses Proliferation, Migration, and Invasion of Human Brain Glioblastoma Multiforme GBM 8401 Cells via PI3K/Akt Pathway |
| Curcumin | Glioblastoma | 29 | PM | 33809462 | 📋 | Anticancer Mechanism of Curcumin on Human Glioblastoma |
| Curcumin | Glioblastoma | 28 | PM | 33322413 | 📋 | Antitumor Activity of Curcumin in Glioblastoma |
| Curcumin | Glioblastoma | 27 | PM | 33092261 | 📋 | The Multi-Faceted Effect of Curcumin in Glioblastoma from Rescuing Cell Clearance to Autophagy-Independent Effects |
| Curcumin | Glioblastoma | 26 | PM | 32575632 | 📋 | Validation of Enhancing Effects of Curcumin on Radiotherapy With F98/ FGT Glioblastoma-Bearing Rat Model |
| Curcumin | Glioblastoma | 16 | PM | 32445778 | 📋 | Curcumin Suppress Glioblastoma Cell Proliferation by p-AKT/mTOR Pathway and Increased the PTEN Expression |
| Curcumin | Glioblastoma | 1 | PM | 32172947 | 📋 | Curcumin-induced Cell Death Depends on the Level of Autophagic Flux in A172 and U87MG Human Glioblastoma Cells |
| Curcumin | Glioblastoma | 2 | PM | 31841506 | 📋 | Combination Treatment of Berberine and Solid Lipid Curcumin Particles Increased Cell Death and Inhibited PI3K/Akt/mTOR Pathway of Human Cultured Glioblastoma Cells More Effectively Than Did Individual Treatments |
| Curcumin | Glioblastoma | 23 | PM | 29969678 | 📋 | Evaluation of Targeted Curcumin (CUR) Loaded PLGA Nanoparticles for in Vitro Photodynamic Therapy on Human Glioblastoma Cell Line |
| Curcumin | Glioblastoma | 14 | PM | 29723631 | 📋 | Paraptosis in Human Glioblastoma Cell Line Induced by Curcumin |
| Curcumin | Glioblastoma | 9 | PM | 28260885 | 📋 | The Functional Curcumin Liposomes Induce Apoptosis in C6 Glioblastoma Cells and C6 Glioblastoma Stem Cells in Vitro and in Animals |
| Curcumin | Glioblastoma | 18 | PM | 28160777 | 📋 | Curcumin Decreases Malignant Characteristics of Glioblastoma Stem Cells via Induction of Reactive Oxygen Species |
| Curcumin | Glioblastoma | 5 | PM | 27543754 | 📋 | Curcumin Changes the Polarity of Tumor-Associated Microglia and Eliminates Glioblastoma |
| Curcumin | Glioblastoma | 4 | PM | 27340742 | 📋 | Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients |
| Curcumin | Glioblastoma | 25 | PM | 26763536 | 📋 | Pharmacological Inhibition of Lipid Droplet Formation Enhances the Effectiveness of Curcumin in Glioblastoma |
| Curcumin | Glioblastoma | 24 | PM | 26748069 | 📋 | Prospective of Curcumin, a Pleiotropic Signalling Molecule From Curcuma Longa in the Treatment of Glioblastoma |
| Curcumin | Glioblastoma | 21 | PM | 26637846 | 📋 | Curcumin for the Treatment of Glioblastoma |
| Curcumin | Glioblastoma | 12 | PM | 26364505 | 📋 | Modulatory Effects of Curcumin and Tyrphostins (AG494 and AG1478) on Growth Regulation and Viability of LN229 Human Brain Cancer Cells |
| Curcumin | Glioblastoma | 11 | PM | 26239619 | 📋 | Induction of microRNA-146a Is Involved in Curcumin-Mediated Enhancement of Temozolomide Cytotoxicity Against Human Glioblastoma |
| Curcumin | Glioblastoma | 6 | PM | 25050915 | 📋 | Curcumin Sensitizes Glioblastoma to Temozolomide by Simultaneously Generating ROS and Disrupting AKT/mTOR Signaling |
| Curcumin | Glioblastoma | 22 | PM | 23621850 | 📋 | Epigenetic Reactivation of RANK in Glioblastoma Cells by Curcumin: Involvement of STAT3 Inhibition |
| Curcumin | Glioblastoma | 10 | PM | 22842701 | 📋 | Induction of Apoptosis and Reduction of MMP Gene Expression in the U373 Cell Line by Polyphenolics in Aronia Melanocarpa and by Curcumin |
| Curcumin | Glioblastoma | 8 | PM | 21775121 | 📋 | The Curry Spice Curcumin Selectively Inhibits Cancer Cells Growth in Vitro and in Preclinical Model of Glioblastoma |
| Curcumin | Glioblastoma | 20 | PM | 20822178 | 📋 | Curcuminoids Suppress the Growth and Induce Apoptosis Through caspase-3-dependent Pathways in Glioblastoma Multiforme (GBM) 8401 Cells |
| Curcumin | Glioblastoma | 13 | PM | 20596601 | 📋 | The Anti-Cancer Efficacy of Curcumin Scrutinized Through Core Signaling Pathways in Glioblastoma |
| Curcumin | Glioblastoma | 7 | PM | 20087857 | 📋 | Curcumin Inhibits Tumor Growth and Angiogenesis in Glioblastoma Xenografts |
| Curcumin | Glioblastoma | 19 | PM | 17596214 | 📋 | Curcumin Suppresses Growth and Chemoresistance of Human Glioblastoma Cells via AP-1 and NFkappaB Transcription Factors |
| Curcumin | Glioblastoma | 15 | PM | 17562168 | 📋 | Curcumin Suppressed Anti-Apoptotic Signals and Activated Cysteine Proteases for Apoptosis in Human Malignant Glioblastoma U87MG Cells |
| Curcumin | Glioblastoma | 3 | PM | 16949208 | 📋 | Curcumin Activated Both Receptor-Mediated and Mitochondria-Mediated Proteolytic Pathways for Apoptosis in Human Glioblastoma T98G Cells |
| Curcumin | Glioma | 25 | PM | 38397870 | 📋 | Action of Curcumin on Glioblastoma Growth: A Systematic Review with Meta-Analysis of Animal Model Studies |
| Curcumin | Glioma | 24 | PM | 36238646 | 📋 | Curcumin Enhanced Ionizing Radiation-Induced Immunogenic Cell Death in Glioma Cells through Endoplasmic Reticulum Stress Signaling Pathways |
| Curcumin | Glioma | 23 | PM | 35790698 | 📋 | Review on the Therapeutic Potential of Curcumin and its Derivatives on Glioma Biology |
| Curcumin | Glioma | 17 | PM | 34829791 | 📋 | Curcumin and Radiotherapy Exert Synergistic Anti-Glioma Effect In Vitro |
| Curcumin | Glioma | 22 | PM | 34169637 | 📋 | Curcumin inhibits adverse psychological stress-induced proliferation and invasion of glioma cells via down-regulating the ERK/MAPK pathway |
| Curcumin | Glioma | 21 | PM | 33574907 | 📋 | HSP60 participates in the anti-glioma effects of curcumin |
| Curcumin | Glioma | 20 | PM | 33231085 | 📋 | Curcumin combined with low-intensity ultrasound suppresses the growth of glioma cells via inhibition of the AKT pathway |
| Curcumin | Glioma | 14 | PM | 31511210 | 📋 | [Curcumin Suppresses Invasiveness and Migration of Human Glioma Cells in Vitro by Inhibiting HDGF/β-catenin Complex] |
| Curcumin | Glioma | 4 | PM | 29588587 | 📋 | Targeted Therapy of Intracranial Glioma Model Mice With Curcumin Nanoliposomes |
| Curcumin | Glioma | 8 | PM | 28627598 | 📋 | Curcumin Exerts Its Tumor Suppressive Function via Inhibition of NEDD4 Oncoprotein in Glioma Cancer Cells |
| Curcumin | Glioma | 16 | PM | 27680947 | 📋 | The Circadian Clock Modulates Anti-Cancer Properties of Curcumin |
| Curcumin | Glioma | 18 | PM | 27373979 | 📋 | Cathepsin L Knockdown Enhances Curcumin-Mediated Inhibition of Growth, Migration, and Invasion of Glioma Cells |
| Curcumin | Glioma | 1 | PM | 27354801 | 📋 | Biodegradable Micelles Enhance the Antiglioma Activity of Curcumin in Vitro and in Vivo |
| Curcumin | Glioma | 19 | PM | 26046466 | 📋 | Curcumin Suppresses Cell Growth and Invasion and Induces Apoptosis by Down-Regulation of Skp2 Pathway in Glioma Cells |
| Curcumin | Glioma | 9 | PM | 22192169 | 📋 | Curcumin Promotes Differentiation of Glioma-Initiating Cells by Inducing Autophagy |
| Curcumin | Glioma | 3 | PM | 21138870 | 📋 | Dietary Curcumin Attenuates Glioma Growth in a Syngeneic Mouse Model by Inhibition of the JAK1,2/STAT3 Signaling Pathway |
| Curcumin | Glioma | 7 | PM | 20840775 | 📋 | The Nontoxic Natural Compound Curcumin Exerts Anti-Proliferative, Anti-Migratory, and Anti-Invasive Properties Against Malignant Gliomas |
| Curcumin | Glioma | 5 | PM | 20089354 | 📋 | Curcumin Inhibits the Side Population (SP) Phenotype of the Rat C6 Glioma Cell Line: Towards Targeting of Cancer Stem Cells With Phytochemicals |
| Curcumin | Glioma | 15 | PM | 19422808 | 📋 | Demethoxycurcumin Induces Bcl-2 Mediated G2/M Arrest and Apoptosis in Human Glioma U87 Cells |
| Curcumin | Glioma | 10 | PM | 17594054 | 📋 | Curcumin Induces G2/M Cell Cycle Arrest in a p53-dependent Manner and Upregulates ING4 Expression in Human Glioma |
| Curcumin | Glioma | 2 | PM | 17395690 | 📋 | Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo Through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways |
| Curcumin | Glioma | 11 | PM | 16777101 | 📋 | Silencing of the Human Microsomal glucose-6-phosphate Translocase Induces Glioma Cell Death: Potential New Anticancer Target for Curcumin |
| Curcumin | Glioma | 6 | PM | 16646663 | 📋 | Curcumin-induced Histone Hypoacetylation Enhances caspase-3-dependent Glioma Cell Death and Neurogenesis of Neural Progenitor Cells |
| Curcumin | Glioma | 13 | PM | 16198311 | 📋 | Curcumin Is a Potent Broad Spectrum Inhibitor of Matrix Metalloproteinase Gene Expression in Human Astroglioma Cells |
| Curcumin | Glioma | 12 | PM | 16102725 | 📋 | Curcumin Suppresses Phorbol Ester-Induced Matrix metalloproteinase-9 Expression by Inhibiting the PKC to MAPK Signaling Pathways in Human Astroglioma Cells |
| Curcumin | Hepatic Encephalopathy | 2 | PM | 34630953 | 📋 | Evaluation of the protective effect of curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats |
| Curcumin | Hepatic Encephalopathy | 1 | PM | 32761362 | 📋 | Curcumin prevents cognitive deficits in the bile duct ligated rats |
| Curcumin | Hydrocephalus | 1 | PM | 35421860 | 📋 | Curcumin Attenuates Hydrocephalus via Activation of E2F Transcription Factor 4 |
| Curcumin | Intracerebral Hemorrhage | 5 | PM | 35571134 | 📋 | Curcumin Restrains Oxidative Stress of After Intracerebral Hemorrhage in Rat by Activating the Nrf2/HO-1 Pathway |
| Curcumin | Intracerebral Hemorrhage | 4 | PM | 35381181 | 📋 | Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing the JAK1/STAT1 pathway |
| Curcumin | Intracerebral Hemorrhage | 3 | PM | 27026486 | 📋 | Curcumin Reduces Brain-Infiltrating T Lymphocytes After Intracerebral Hemorrhage in Mice |
| Curcumin | Intracerebral Hemorrhage | 1 | PM | 26119880 | 📋 | Curcumin Attenuates Brain Edema in Mice With Intracerebral Hemorrhage Through Inhibition of AQP4 and AQP9 Expression |
| Curcumin | Intracerebral Hemorrhage | 2 | PM | 12578124 | 📋 | Differential Regulation of Cytokines and Transcription Factors in Liver by Curcumin Following Hemorrhage/Resuscitation |
| Curcumin | Ischemic Stroke | 7 | PM | 38082237 | 📋 | The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial |
| Curcumin | Ischemic Stroke | 6 | PM | 37915409 | 📋 | Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke |
| Curcumin | Ischemic Stroke | 5 | PM | 36598916 | 📋 | Curcumin's mechanism of action against ischemic stroke: A network pharmacology and molecular dynamics study |
| Curcumin | Ischemic Stroke | 4 | PM | 35559238 | 📋 | Mechanisms Underlying Curcumin-Induced Neuroprotection in Cerebral Ischemia |
| Curcumin | Ischemic Stroke | 3 | PM | 34630845 | 📋 | Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF- κ B Suppression and NLRP3 Inflammasome Inhibition |
| Curcumin | Ischemic Stroke | 2 | PM | 34055082 | 📋 | Curcumin ameliorates ischemic stroke injury in rats by protecting the integrity of the blood-brain barrier |
| Curcumin | Ischemic Stroke | 1 | PM | 25878600 | 📋 | Curcumin Pretreatment and Post-Treatment Both Improve the Antioxidative Ability of Neurons With Oxygen-Glucose Deprivation |
| Curcumin | Memory Disorders | 18 | PM | 35327278 | 📋 | Curcumin Suppresses Lead-Induced Inflammation and Memory Loss in Mouse Model and In Silico Molecular Docking |
| Curcumin | Memory Disorders | 19 | PM | 34536813 | 📋 | Behavioral and morphological effects of resveratrol and curcumin in rats submitted to doxorubicin-induced cognitive impairment |
| Curcumin | Memory Disorders | 17 | PM | 34405526 | 📋 | Curcumin improves memory deficits by inhibiting HMGB1-RAGE/TLR4-NF-κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus |
| Curcumin | Memory Disorders | 15 | PM | 32447261 | 📋 | Premature Synaptic Mitochondrial Dysfunction in the Hippocampus During Aging Contributes to Memory Loss |
| Curcumin | Memory Disorders | 4 | PM | 27491636 | 📋 | Curcumin Improves Episodic Memory in Cadmium Induced Memory Impairment Through Inhibition of Acetylcholinesterase and Adenosine Deaminase Activities in a Rat Model |
| Curcumin | Memory Disorders | 13 | PM | 27388114 | 📋 | Amelioration of Scopolamine-Induced Amnesia by Phosphatidylserine and Curcumin in the Day-Old Chick |
| Curcumin | Memory Disorders | 16 | PM | 26274972 | 📋 | Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions |
| Curcumin | Memory Disorders | 14 | PM | 26019804 | 📋 | Interaction Between the Antioxidant Activity of Curcumin and Cholinergic System on Memory Retention in Adult Male Wistar Rats |
| Curcumin | Memory Disorders | 11 | PM | 20538041 | 📋 | Curcuminoids Enhance Memory in an Amyloid-Infused Rat Model of Alzheimer's Disease |
| Curcumin | Memory Disorders | 3 | PM | 20369229 | 📋 | Involvement of PPAR-gamma in Curcumin-Mediated Beneficial Effects in Experimental Dementia |
| Curcumin | Memory Disorders | 10 | PM | 20026275 | 📋 | Effect of Curcumin on Brain Insulin Receptors and Memory Functions in STZ (ICV) Induced Dementia Model of Rat |
| Curcumin | Memory Disorders | 2 | PM | 19925811 | 📋 | Protective Effect of Curcumin Against Intracerebral Streptozotocin Induced Impairment in Memory and Cerebral Blood Flow |
| Curcumin | Memory Disorders | 7 | PM | 19765566 | 📋 | Curcumin Is Protective Against Phenytoin-Induced Cognitive Impairment and Oxidative Stress in Rats |
| Curcumin | Memory Disorders | 9 | PM | 19540859 | 📋 | Curcumin Reverses Impaired Cognition and Neuronal Plasticity Induced by Chronic Stress |
| Curcumin | Memory Disorders | 1 | PM | 19234767 | 📋 | Curcumin Ameliorates Impaired insulin/IGF Signalling and Memory Deficit in a Streptozotocin-Treated Rat Model |
| Curcumin | Memory Disorders | 8 | PM | 19161989 | 📋 | Curcumin-induced Degradation of PKC Delta Is Associated With Enhanced Dentate NCAM PSA Expression and Spatial Learning in Adult and Aged Wistar Rats |
| Curcumin | Memory Disorders | 5 | PM | 18701050 | 📋 | Curcumin Improves Learning and Memory Ability and Its Neuroprotective Mechanism in Mice |
| Curcumin | Memory Disorders | 6 | PM | 18394334 | 📋 | [Effect and Mechanism of Curcumin on Learning and Memory Dysfunction Induced by gp120 in Rats] |
| Curcumin | Memory Disorders | 12 | PM | 17263510 | 📋 | Curcuminoids, Curcumin, and Demethoxycurcumin Reduce Lead-Induced Memory Deficits in Male Wistar Rats |
| Curcumin | Memory Performance | 3 | PM | 34409523 | 📋 | Therapeutic Potential of Curcumin in Reversing the Depression and Associated Pseudodementia via Modulating Stress Hormone, Hippocampal Neurotransmitters, and BDNF Levels in Rats |
| Curcumin | Memory Performance | 1 | PM | 32512782 | 📋 | Further Evidence of Benefits to Mood and Working Memory From Lipidated Curcumin in Healthy Older People: A 12-Week, Double-Blind, Placebo-Controlled, Partial Replication Study |
| Curcumin | Memory Performance | 2 | PM | 25869755 | 📋 | Pretreatment With Curcumin Attenuates Anxiety While Strengthens Memory Performance After One Short Stress Experience in Male Rats |
| Curcumin | Migraine | 6 | PM | 37216708 | 📋 | The impact of curcumin on migraine: A comprehensive review |
| Curcumin | Migraine | 5 | PM | 35070194 | 📋 | Effects of Curcumin Supplementation on Clinical Features and Inflammation, in Migraine Patients: A Double-Blind Controlled, Placebo Randomized Clinical Trial |
| Curcumin | Migraine | 4 | PM | 32727335 | 📋 | Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano-Curcumin on Migraine Patients, from Cellular to Clinical Insight: A Randomized, Double Blind, and Placebo-Controlled Trial |
| Curcumin | Migraine | 2 | PM | 31287810 | 📋 | Liposomal Curcumin Enhances the Effect of Naproxen in a Rat Model of Migraine |
| Curcumin | Migraine | 3 | PM | 31241007 | 📋 | The Synergistic Effects of Nano-Curcumin and Coenzyme Q10 Supplementation in Migraine Prophylaxis: A Randomized, Placebo-Controlled, Double-Blind Trial |
| Curcumin | Migraine | 1 | PM | 28478481 | 📋 | The Synergistic Effects of ω-3 Fatty Acids and Nano-Curcumin Supplementation on Tumor Necrosis Factor (TNF)-α Gene Expression and Serum Level in Migraine Patients |
| Curcumin | Mild Cognitive Impairment | 9 | PM | 29614668 | 📋 | A Study of a Supplement Containing Huperzine A and Curcumin in Dementia Patients and Individuals With Mild Cognitive Impairment |
| Curcumin | Psychiatric Disorders | 3 | PM | 38672750 | 📋 | Curcumin as a Multifunctional Spice Ingredient against Mental Disorders in Humans: Current Clinical Studies and Bioavailability Concerns |
| Curcumin | Psychiatric Disorders | 2 | PM | 35482938 | 📋 | Therapeutic role of curcumin in adult neurogenesis for management of psychiatric and neurological disorders: a scientometric study to an in-depth review |
| Curcumin | Psychiatric Disorders | 1 | PM | 35204235 | 📋 | An Update on the Exploratory Use of Curcumin in Neuropsychiatric Disorders |
| Curcumin | Schizophrenia | 1 | PM | 35655971 | 📋 | Role of Curcumin in the Management of Schizophrenia: A Narrative Review |
| Curcumin | Stress | 12 | PM | 33460863 | 📋 | Continuous exposure to amorphous formula of curcumin from the developmental stage facilitates anti-anxiety-like behavior and fear-extinction learning in rats |
| Curcumin | Stress | 2 | PM | 30542090 | 📋 | A Diet Enriched With Curcumin Promotes Resilience to Chronic Social Defeat Stress |
| Curcumin | Stress | 6 | PM | 25869755 | 📋 | Pretreatment With Curcumin Attenuates Anxiety While Strengthens Memory Performance After One Short Stress Experience in Male Rats |
| Curcumin | Stress | 10 | PM | 23876788 | 📋 | Antidepressant-like Effects of Curcumin in Chronic Mild Stress of Rats: Involvement of Its Anti-Inflammatory Action |
| Curcumin | Stress | 4 | PM | 20633542 | 📋 | GABAergic and Nitriergic Modulation by Curcumin for Its Antianxiety-Like Activity in Mice |
| Curcumin | Stress | 5 | PM | 19302828 | 📋 | Antidepressant-like Effects of Curcumin on Serotonergic Receptor-Coupled AC-cAMP Pathway in Chronic Unpredictable Mild Stress of Rats |
| Curcumin | Stroke | 8 | PM | 35914679 | 📋 | The action of curcumin against damage resulting from cerebral stroke: a systematic review |
| Curcumin | Stroke | 2 | PM | 29490624 | 📋 | Curcumin Prevents Strokes in Stroke-Prone Spontaneously Hypertensive Rats by Improving Vascular Endothelial Function |
| Curcumin | Stroke | 1 | PM | 26119880 | 📋 | Curcumin Attenuates Brain Edema in Mice With Intracerebral Hemorrhage Through Inhibition of AQP4 and AQP9 Expression |
| Curcumin | Stroke | 6 | PM | 25878600 | 📋 | Curcumin Pretreatment and Post-Treatment Both Improve the Antioxidative Ability of Neurons With Oxygen-Glucose Deprivation |
| Curcumin | Stroke | 7 | PM | 24788895 | 📋 | Epigenetic Impact of Curcumin on Stroke Prevention |
| Curcumin | Stroke | 5 | PM | 21158690 | 📋 | Neuroprotective and Neurotrophic Curcuminoids to Treat Stroke: A Translational Perspective |
| Curcumin | Stroke | 4 | PM | 19774461 | 📋 | Curcumin Improves Outcomes and Attenuates Focal Cerebral Ischemic Injury via Antiapoptotic Mechanisms in Rats |
| Curcumin | Stroke | 3 | PM | 18611416 | 📋 | Dose Dependence and Therapeutic Window for the Neuroprotective Effects of Curcumin in Thromboembolic Model of Rat |
| Curcumin | Subarachnoid Hemorrhage | 1 | PM | 27979493 | 📋 | Curcumin Attenuates Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice |
| Curcumin | Subarachnoid Hemorrhage | 3 | PM | 26551062 | 📋 | Evidence for the Protective Effects of Curcumin Against Oxyhemoglobin-Induced Injury in Rat Cortical Neurons |
| Curcumin | Subarachnoid Hemorrhage | 2 | PM | 18752423 | 📋 | Curcumin Attenuates Vascular Inflammation and Cerebral Vasospasm After Subarachnoid Hemorrhage in Mice |
| Curcumin | Traumatic Brain Injury | 17 | PM | 38798711 | 📋 | Curcumin in the treatment of inflammation and oxidative stress responses in traumatic brain injury: a systematic review and meta-analysis |
| Curcumin | Traumatic Brain Injury | 16 | PM | 38562043 | 📋 | Curcumin Lowers the Accelerated Speed of Epileptogenesis by Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 15 | PM | 38032526 | 📋 | Curcumin alleviates traumatic brain injury induced by gas explosion through modulating gut microbiota and suppressing the LPS/TLR4/MyD88/NF-κB pathway |
| Curcumin | Traumatic Brain Injury | 14 | PM | 37478644 | 📋 | Curcumin ameliorates traumatic brain injury via C1ql3-mediated microglia M2 polarization |
| Curcumin | Traumatic Brain Injury | 13 | PM | 36872351 | 📋 | Curcumin Alleviates Oxidative stress, Neuroinflammation, and Promotes Behavioral Recovery after Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 12 | PM | 36055110 | 📋 | Protective effects of curcumin against traumatic brain injury |
| Curcumin | Traumatic Brain Injury | 11 | PM | 35080289 | 📋 | Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway |
| Curcumin | Traumatic Brain Injury | 10 | PM | 34080237 | 📋 | Effects of curcuminoids on inflammatory and oxidative stress biomarkers and clinical outcomes in critically ill patients: A randomized double-blind placebo-controlled trial |
| Curcumin | Traumatic Brain Injury | 9 | PM | 33548799 | 📋 | In Situ implantable, post-trauma microenvironment-responsive, ROS Depletion Hydrogels for the treatment of Traumatic brain injury |
| Curcumin | Traumatic Brain Injury | 8 | PM | 32502596 | 📋 | Curcumin Alleviates Neuroinflammation, Enhances Hippocampal Neurogenesis, and Improves Spatial Memory After Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 6 | PM | 24669820 | 📋 | Curcumin Attenuates Acute Inflammatory Injury by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway in Experimental Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 4 | PM | 23932920 | 📋 | Curcumin Pretreatment Attenuates Brain Lesion Size and Improves Neurological Function Following Traumatic Brain Injury in the Rat |
| Curcumin | Traumatic Brain Injury | 2 | PM | 20132469 | 📋 | Curcumin Attenuates Cerebral Edema Following Traumatic Brain Injury in Mice: A Possible Role for aquaporin-4? |
| Curcumin | Traumatic Brain Injury | 1 | PM | 20129497 | 📋 | Antioxidant Therapies for Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 3 | PM | 19393301 | 📋 | Dietary Curcumin Supplementation Counteracts Reduction in Levels of Molecules Involved in Energy Homeostasis After Brain Trauma |
| Curcumin | Traumatic Brain Injury | 5 | PM | 16364299 | 📋 | Dietary Curcumin Counteracts the Outcome of Traumatic Brain Injury on Oxidative Stress, Synaptic Plasticity, and Cognition |
| Curcumin | Traumatic Brain Injury | 7 | PM | 16266725 | 📋 | Prevention of Kainic Acid-Induced Changes in Nitric Oxide Level and Neuronal Cell Damage in the Rat Hippocampus by Manganese Complexes of Curcumin and Diacetylcurcumin |
