| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Cocoa | Aging Brain | 3 | PM | 35883844 | 📋 | Chocolate and Cocoa-Derived Biomolecules for Brain Cognition during Ageing |
| Cocoa | Aging Brain | 2 | PM | 35010877 | 📋 | Neurocognitive Effects of Cocoa and Red-Berries Consumption in Healthy Adults |
| Cocoa | Aging Brain | 1 | PM | 34504131 | 📋 | Cacao powder supplementation attenuates oxidative stress, cholinergic impairment, and apoptosis in D-galactose-induced aging rat brain |
| Cocoa | Alzheimer's Disease | 3 | PM | 38756381 | 📋 | Cacao consumption improves passive avoidance memory impairment in a rat model of Alzheimer's disease: the role of hippocampal synaptic plasticity and oxidative stress |
| Cocoa | Alzheimer's Disease | 2 | PM | 34329196 | 📋 | Chocolate consumption and all-cause and cause-specific mortality in a US population: a post hoc analysis of the PLCO cancer screening trial |
| Cocoa | Alzheimer's Disease | 1 | PM | 26402120 | 📋 | Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer's Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging |
| Cocoa | Cognitive Performance | 8 | PM | 38268830 | 📋 | The effects of dark chocolate on cognitive performance during cognitively demanding tasks: A randomized, single-blinded, crossover, dose-comparison study |
| Cocoa | Cognitive Performance | 7 | PM | 38201871 | 📋 | Cacao Polyphenol-Rich Dark Chocolate Intake Contributes to Efficient Brain Activity during Cognitive Tasks: A Randomized, Single-Blinded, Crossover, and Dose-Comparison fMRI Study |
| Cocoa | Cognitive Performance | 6 | PM | 37777571 | 📋 | Concomitant dual-site tDCS and dark chocolate improve cognitive and endurance performance following cognitive effort under hypoxia: a randomized controlled trial |
| Cocoa | Cognitive Performance | 2 | PM | 37471213 | 📋 | Cocoa flavanols protect cognitive function, cerebral oxygenation, and mental fatigue during severe hypoxia |
| Cocoa | Cognitive Performance | 1 | PM | 37211619 | 📋 | Effects of chocolate on cognitive function in healthy adults: A systematic review and meta-analysis on clinical trials |
| Cocoa | Cognitive Performance | 5 | PM | 33265948 | 📋 | Effect of Cocoa and Cocoa Products on Cognitive Performance in Young Adults |
| Cocoa | Cognitive Performance | 4 | PM | 31933112 | 📋 | Effects of Cocoa-Derived Polyphenols on Cognitive Function in Humans. Systematic Review and Analysis of Methodological Aspects |
| Cocoa | Cognitive Performance | 3 | PM | 31744119 | 📋 | Sub-Chronic Consumption of Dark Chocolate Enhances Cognitive Function and Releases Nerve Growth Factors: A Parallel-Group Randomized Trial |
| Cocoa | Depression | 3 | PM | 34033845 | 📋 | Epicatechin treatment generates resilience to chronic mild stress-induced depression in a murine model |
| Cocoa | Depression | 1 | PM | 31356717 | 📋 | Is there a relationship between chocolate consumption and symptoms of depression? A cross-sectional survey of 13,626 US adults |
| Cocoa | Depression | 2 | PM | 20421555 | 📋 | Mood food: chocolate and depressive symptoms in a cross-sectional analysis |
| Cocoa | Diabetic Encephalopathy | 1 | PM | 31236643 | 📋 | The effect of acute cocoa flavanol intake on the BOLD response and cognitive function in type 1 diabetes: a randomized, placebo-controlled, double-blinded cross-over pilot study |
| Cocoa | Memory Performance | 3 | PM | 37252983 | 📋 | Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption |
| Cocoa | Memory Performance | 1 | PM | 32075015 | 📋 | Beneficial Effects of Dark Chocolate for Episodic Memory in Healthy Young Adults: A Parallel-Groups Acute Intervention with a White Chocolate Control |
| Cocoa | Memory Performance | 2 | PM | 27088635 | 📋 | Flavanol-rich chocolate acutely improves arterial function and working memory performance counteracting the effects of sleep deprivation in healthy individuals |
| Cocoa | Stress | 2 | PM | 33801767 | 📋 | Cocoa Flavanols Improve Vascular Responses to Acute Mental Stress in Young Healthy Adults |
| Cocoa | Stress | 3 | PM | 32247223 | 📋 | Dietary natural cocoa ameliorates disrupted circadian rhythms in locomotor activity and sleep-wake cycles in mice with chronic sleep disorders caused by psychophysiological stress |
| Cocoa | Stress | 1 | PM | 19810704 | 📋 | Metabolic effects of dark chocolate consumption on energy, gut microbiota, and stress-related metabolism in free-living subjects |
| Cocoa | Stroke | 1 | PM | 28671591 | 📋 | Chocolate Consumption and Risk of Coronary Heart Disease, Stroke, and Diabetes: A Meta-Analysis of Prospective Studies |
| Cocoa | Stroke | 3 | PM | 28324761 | 📋 | Chocolate consumption and risk of stroke among men and women: A large population-based, prospective cohort study |
| Cocoa | Stroke | 2 | PM | 21875885 | 📋 | Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis |
