| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Baicalin | Alzheimer's Disease | 4 | PM | 37719746 | 📋 | An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer's disease rat model |
| Baicalin | Alzheimer's Disease | 3 | PM | 35528169 | 📋 | Baicalin Attenuated A β 1-42-Induced Apoptosis in SH-SY5Y Cells by Inhibiting the Ras-ERK Signaling Pathway |
| Baicalin | Alzheimer's Disease | 2 | PM | 35103832 | 📋 | Baicalin attenuates amyloid β oligomers induced memory deficits and mitochondria fragmentation through regulation of PDE-PKA-Drp1 signalling |
| Baicalin | Alzheimer's Disease | 1 | PM | 17480132 | 📋 | Alzheimer's Disease Drug Discovery From Herbs: Neuroprotectivity From Beta-Amyloid (1-42) Insult |
| Baicalin | Brain Edema | 2 | PM | 12212190 | 📋 | [Protective Effects of Baicalin, Mannitol and Dexamethasone on Infective Brain Edema in Rats] |
| Baicalin | Brain Edema | 1 | PM | 11038818 | 📋 | [The Protective Effects of Baicalin on Pertussis Bacilli-Induced Brain Edema in Rats] |
| Baicalin | Brain Inflammation | 1 | PM | 17204294 | 📋 | The Flavonoid Baicalin Protects Against Cerebrovascular Dysfunction and Brain Inflammation in Experimental Heatstroke |
| Baicalin | Cerebral Hypoperfusion | 1 | PM | 36707260 | 📋 | Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling |
| Baicalin | Cerebral Ischemia | 5 | PM | 38114182 | 📋 | [Baicalin improves inflammatory response of human microglia by regulating cAMP-PKA-NF-κB/CREB pathway] |
| Baicalin | Cerebral Ischemia | 4 | PM | 35265682 | 📋 | Modular Screening Reveals Driver Induced Additive Mechanisms of Baicalin and Jasminoidin on Cerebral Ischemia Therapy |
| Baicalin | Cerebral Ischemia | 3 | PM | 34699947 | 📋 | Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis |
| Baicalin | Cerebral Ischemia | 2 | PM | 34306315 | 📋 | Baicalein, Baicalin, and Wogonin: Protective Effects against Ischemia-Induced Neurodegeneration in the Brain and Retina |
| Baicalin | Cerebral Ischemia | 1 | PM | 33891262 | 📋 | Baicalin and Geniposide Inhibit Polarization and Inflammatory Injury of OGD/R-Treated Microglia by Suppressing the 5-LOX/LTB4 Pathway |
| Baicalin | Cerebral Ischemia-Reperfusion | 5 | PM | 38579645 | 📋 | Baicalin attenuates neuronal damage associated with SDH activation and PDK2-PDH axis dysfunction in early reperfusion |
| Baicalin | Cerebral Ischemia-Reperfusion | 4 | PM | 38428662 | 📋 | FDA compound library screening Baicalin upregulates TREM2 for the treatment of cerebral ischemia-reperfusion injury |
| Baicalin | Cerebral Ischemia-Reperfusion | 3 | PM | 35285204 | 📋 | [Baicalin treats cerebral ischemia reperfusion-induced brain edema in rats by inhibiting TRPV4 and AQP4 of astrocytes] |
| Baicalin | Cerebral Ischemia-Reperfusion | 2 | PM | 34234667 | 📋 | Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures |
| Baicalin | Cerebral Ischemia-Reperfusion | 1 | PM | 34080089 | 📋 | Baicalin Inhibits NLRP3 Inflammasome Activity Via the AMPK Signaling Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury |
| Baicalin | Cognitive Disorders | 4 | PM | 34321866 | 📋 | Baicalin Rescues Cognitive Dysfunction, Mitigates Neurodegeneration, and Exerts Anti-Epileptic Effects Through Activating TLR4/MYD88/Caspase-3 Pathway in Rats |
| Baicalin | Cognitive Disorders | 3 | PM | 34280458 | 📋 | Baicalin Ameliorates Chronic Unpredictable Mild Stress-Induced Depression through the BDNF/ERK/CREB Signaling Pathway |
| Baicalin | Cognitive Disorders | 1 | PM | 33029280 | 📋 | Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway |
| Baicalin | Depression | 12 | PM | 37820491 | 📋 | Widely targeted metabolomics unveils baicalin-induced hippocampal metabolic alternations in a rat model of chronic unpredictable mild stress |
| Baicalin | Depression | 11 | PM | 36642102 | 📋 | Baicalin attenuates chronic unpredictable mild stress-induced hippocampal neuronal apoptosis through regulating SIRT1/PARP1 signaling pathway |
| Baicalin | Depression | 10 | PM | 36607586 | 📋 | Baicalin Ameliorates Corticosterone-Induced Depression by Promoting Neurodevelopment of Hippocampal via mTOR/GSK3 β Pathway |
| Baicalin | Depression | 9 | PM | 36531636 | 📋 | Baicalin improves the energy levels in the prefrontal cortex of mice exposed to chronic unpredictable mild stress |
| Baicalin | Depression | 8 | PM | 36463946 | 📋 | Baicalin ameliorates CUMS-induced depression-like behaviors through activating AMPK/PGC-1α pathway and enhancing NIX-mediated mitophagy in mice |
| Baicalin | Depression | 7 | PM | 35432561 | 📋 | Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats |
| Baicalin | Depression | 5 | PM | 34280458 | 📋 | Baicalin Ameliorates Chronic Unpredictable Mild Stress-Induced Depression through the BDNF/ERK/CREB Signaling Pathway |
| Baicalin | Depression | 4 | PM | 33964281 | 📋 | Baicalin promotes hippocampal neurogenesis via the Wnt/β-catenin pathway in a chronic unpredictable mild stress-induced mouse model of depression |
| Baicalin | Depression | 3 | PM | 33025359 | 📋 | A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α |
| Baicalin | Depression | 2 | PM | 32982755 | 📋 | Facilitating Granule Cell Survival and Maturation in Dentate Gyrus With Baicalin for Antidepressant Therapeutics |
| Baicalin | Depression | 1 | PM | 32643091 | 📋 | Baicalin Attenuates Inflammatory Pain Associated Depressive Symptoms via Akt-mediated Adult Hippocampal Neurogenesis |
| Baicalin | Depression | 6 | PM | 31440134 | 📋 | Revealing Antidepressant Mechanisms of Baicalin in Hypothalamus Through Systems Approaches in Corticosterone- Induced Depressed Mice |
| Baicalin | Diabetic Encephalopathy | 1 | PM | 38631145 | 📋 | Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment |
| Baicalin | Encephalitis | 1 | PM | 17653455 | 📋 | Baicalin Reduces the Severity of Experimental Autoimmune Encephalomyelitis |
| Baicalin | Encephalomyelitis | 1 | PM | 17653455 | 📋 | Baicalin Reduces the Severity of Experimental Autoimmune Encephalomyelitis |
| Baicalin | Glioblastoma | 1 | PM | 16914050 | 📋 | Anticancer Activity of Extracts Derived From the Mature Roots of Scutellaria Baicalensis on Human Malignant Brain Tumor Cells |
| Baicalin | Intracerebral Hemorrhage | 1 | PM | 33815110 | 📋 | Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage |
| Baicalin | Intracranial Hypertension | 1 | PM | 11783272 | 📋 | [Effect of Baicalin and Tetramethylpyrazine on Intracranial Hypertension of Infectious Brain Edema in Rabbits] |
| Baicalin | Ischemic Stroke | 3 | PM | 36661075 | 📋 | Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury |
| Baicalin | Ischemic Stroke | 2 | PM | 34234667 | 📋 | Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures |
| Baicalin | Ischemic Stroke | 1 | PM | 32473460 | 📋 | Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation |
| Baicalin | Memory Disorders | 3 | PM | 35103832 | 📋 | Baicalin attenuates amyloid β oligomers induced memory deficits and mitochondria fragmentation through regulation of PDE-PKA-Drp1 signalling |
| Baicalin | Memory Disorders | 1 | PM | 16129477 | 📋 | Scutellaria Flavonoid Reduced Memory Dysfunction and Neuronal Injury Caused by Permanent Global Ischemia in Rats |
| Baicalin | Postoperative Cognitive Dysfunction | 1 | PM | 33378842 | 📋 | Protective effect of baicalin against cognitive memory dysfunction after splenectomy in aged rats and its underlying mechanism |
| Baicalin | Stress | 1 | PM | 17639560 | 📋 | Schizandra Chinensis and Scutellaria Baicalensis Counter Stress Behaviors in Mice |
| Baicalin | Stroke | 1 | PM | 16129477 | 📋 | Scutellaria Flavonoid Reduced Memory Dysfunction and Neuronal Injury Caused by Permanent Global Ischemia in Rats |
| Baicalin | Subarachnoid Hemorrhage | 1 | PM | 34704542 | 📋 | Baicalin suppresses autophagy-dependent ferroptosis in early brain injury after subarachnoid hemorrhage |
