| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Metformin | Asthma | 2 | PM | 37772681 | 📋 | Metformin use is associated with decreased asthma exacerbations in adolescents and young adults |
| Metformin | Asthma | 1 | PM | 36547818 | 📋 | Metformin regulates the effects of IR and IGF-1R methylation on mast cell activation and airway reactivity in diabetic rats with asthma through miR-152-3p/DNMT1 axis |
| Metformin | Autism Spectrum Disorder | 1 | PM | 37133558 | 📋 | The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy |
| Metformin | Chronic Inflammation | 3 | PM | 37967593 | 📋 | Metformin attenuates inflammation and boosts autophagy in the liver and intestine of chronologically aged rats |
| Metformin | Chronic Inflammation | 1 | PM | 35890109 | 📋 | Metabolic Action of Metformin |
| Metformin | Chronic Inflammation | 2 | PM | 28935544 | 📋 | Metformin improves obesity-associated inflammation by altering macrophages polarization |
| Metformin | Diabetes Type 1 | 8 | PM | 37528147 | 📋 | Influence of rutin and its combination with metformin on vascular functions in type 1 diabetes |
| Metformin | Diabetes Type 1 | 7 | PM | 37154572 | 📋 | Effects of metformin on glycaemic variability in combination with insulin in overweight/obese patients with type 1 diabetes |
| Metformin | Diabetes Type 1 | 6 | PM | 35954309 | 📋 | The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved |
| Metformin | Diabetes Type 1 | 5 | PM | 35707462 | 📋 | Effect and Safety of Adding Metformin to Insulin Therapy in Treating Adolescents With Type 1 Diabetes Mellitus: An Updated Meta-Analysis of 10 Randomized Controlled Trials |
| Metformin | Diabetes Type 1 | 4 | PM | 35480484 | 📋 | Potential of honey against the onset of autoimmune diabetes and its associated nephropathy, pancreatitis, and retinopathy in type 1 diabetic animal model |
| Metformin | Diabetes Type 1 | 1 | PM | 28988684 | 📋 | A nutraceutical combination of Cinnamomum cassia &Nigella sativa for Type 1 diabetes mellitus |
| Metformin | Diabetes Type 1 | 2 | PM | 27790139 | 📋 | Garlic and Resveratrol Attenuate Diabetic Complications, Loss of β-Cells, Pancreatic and Hepatic Oxidative Stress in Streptozotocin-Induced Diabetic Rats |
| Metformin | Diabetes Type 1 | 3 | PM | 19391322 | 📋 | Hypoglycemic and hypolipidemic effects of methanol seed extract of Citrus paradisi Macfad (Rutaceae) in alloxan-induced diabetic Wistar rats |
| Metformin | Multiple Sclerosis | 2 | PM | 37904733 | 📋 | The AMPK activator metformin improves recovery from demyelination by shifting oligodendrocyte bioenergetics and accelerating OPC differentiation |
| Metformin | Multiple Sclerosis | 1 | PM | 37890574 | 📋 | Metformin treatment reduces inflammation, dysmyelination and disease severity in a mouse model of multiple sclerosis, experimental autoimmune encephalomyelitis |
| Metformin | Peripheral Neuropathy | 3 | PM | 37583905 | 📋 | Efficacy of metformin in prevention of paclitaxel-induced peripheral neuropathy in breast cancer patients: a randomized controlled trial |
| Metformin | Peripheral Neuropathy | 2 | PM | 37131014 | 📋 | The Effect of Metformin on Chemotherapy-Induced Toxicities in Non-diabetic Breast Cancer Patients: A Randomised Controlled Study |
| Metformin | Peripheral Neuropathy | 1 | PM | 36902821 | 📋 | Reduction in the Risk of Peripheral Neuropathy and Lower Decrease in Kidney Function with Metformin, Linagliptin or Their Fixed-Dose Combination Compared to Placebo in Prediabetes: A Randomized Controlled Trial |
| Metformin | Primary Biliary Cholangitis | 1 | PM | 37307826 | 📋 | The inhibition of YAP Signaling Prevents Chronic Biliary Fibrosis in the Abcb4-/- Model by Modulation of Hepatic Stellate Cell and Bile Duct Epithelium Cell Pathophysiology |
| Metformin | Psoriasis | 1 | PM | 38028405 | 📋 | The efficacy of metformin for the treatment of psoriasis: a meta-analysis study |
| Metformin | Rheumatoid Arthritis | 4 | PM | 37964313 | 📋 | Effects of metformin therapy on HMGB1 levels in rheumatoid arthritis patients |
| Metformin | Rheumatoid Arthritis | 2 | PM | 37048545 | 📋 | Metformin Treatment Reduces the Incidence of Rheumatoid Arthritis: A Two-Sample Mendelian Randomized Study |
| Metformin | Rheumatoid Arthritis | 1 | PM | 33453674 | 📋 | Metformin and omega-3 fish oil elicit anti-inflammatory effects via modulation of some dysregulated micro RNAs expression and signaling pathways in experimental induced arthritis |
| Metformin | Rheumatoid Arthritis | 3 | PM | 32828146 | 📋 | Metformin repositioning in rheumatoid arthritis |
| Metformin | Ulcerative Colitis | 1 | PM | 35724510 | 📋 | Combining the HSP90 inhibitor TAS-116 with metformin effectively degrades the NLRP3 and attenuates inflammasome activation in rats: A new management paradigm for ulcerative colitis |
| Metformin | Ulcerative Colitis | 2 | PM | 29653414 | 📋 | New insights on the modulatory roles of metformin or alpha-lipoic acid versus their combination in dextran sulfate sodium-induced chronic colitis in rats |
