Substance | Condition | Seq | Src | PMID | Dtl | Title |
Thymoquinone | AGE Products | 2 | PM | 37741485 | 📋 | Protective effect of thymoquinone on glycation of human myoglobin induced by d-ribose |
Thymoquinone | AGE Products | 1 | PM | 17582594 | 📋 | Thymoquinone decreases AGE-induced NF-kappaB activation in proximal tubular epithelial cells |
Thymoquinone | Age-Related Diseases | 1 | PM | 34202112 | 📋 | Thymoquinone and Curcumin Defeat Aging-Associated Oxidative Alterations Induced by D-Galactose in Rats' Brain and Heart |
Thymoquinone | Age-Related Hearing Loss | 1 | PM | 34507120 | 📋 | Thymoquinone ameliorates age-related hearing loss in C57BL/6J mice by modulating Sirt1 activity and Bak1 expression |
Thymoquinone | Age-Related Macular Degeneration | 1 | PM | 35308121 | 📋 | Thymoquinone in Ocular Neurodegeneration: Modulation of Pathological Mechanisms via Multiple Pathways |
Thymoquinone | Aging | 1 | PM | 32793594 | 📋 | In vitro Evaluation of the Anti-inflammatory Effects of Thymoquinone in Osteoarthritis and in silico Analysis of Inter-Related Pathways in Age-Related Degenerative Diseases |
Thymoquinone | Alzheimer's Disease | 10 | PM | 38031940 | 📋 | Effects of thymoquinone and memantine alone and in combination on memory and hippocampal morphology in rats with streptozotocin-induced Alzheimer's disease |
Thymoquinone | Alzheimer's Disease | 9 | PM | 37764343 | 📋 | The Potential Neuroprotective Effect of Thymoquinone on Scopolamine-Induced In Vivo Alzheimer's Disease-like Condition: Mechanistic Insights |
Thymoquinone | Alzheimer's Disease | 8 | PM | 36273456 | 📋 | The Effect of Thymoquinone on Oxidative Stress Parameters and Apolipoprotein E in Alzheimer Model in Rats |
Thymoquinone | Alzheimer's Disease | 7 | PM | 35832342 | 📋 | Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer's disease |
Thymoquinone | Alzheimer's Disease | 6 | PM | 35722728 | 📋 | Investigating binding mechanism of thymoquinone to human transferrin, targeting Alzheimer's disease therapy |
Thymoquinone | Alzheimer's Disease | 5 | PM | 35718231 | 📋 | Effects of thymoquinone on scopolamine-induced spatial and echoic memory changes through regulation of lipid peroxidation and cholinergic impairment |
Thymoquinone | Alzheimer's Disease | 4 | PM | 35440326 | 📋 | Therapeutic effects of thymoquinone on Alzheimer's disease through modulating amyloid beta neurotoxicity and neuro-inflammatory cytokine levels |
Thymoquinone | Alzheimer's Disease | 3 | PM | 34570578 | 📋 | Investigation of the protective effect of thymoquinone of U87 cells induced by beta-amyloid |
Thymoquinone | Alzheimer's Disease | 1 | PM | 32920292 | 📋 | Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta 1-42 infused rat model |
Thymoquinone | Alzheimer's Disease | 2 | PM | 29405769 | 📋 | Thymoquinone alleviates the experimentally induced Alzheimer's disease inflammation by modulation of TLRs signaling |
Thymoquinone | Chronic Disease | 1 | PM | 36142148 | 📋 | The Role of Thymoquinone in Inflammatory Response in Chronic Diseases |
Thymoquinone | Hypertension | 2 | PM | 35791479 | 📋 | The inhibitory effects of lycopene and thymoquinone on angiotensin converting enzyme from human plasma (An in vitro study) |
Thymoquinone | Hypertension | 1 | PM | 30269105 | 📋 | The standardized extract of Nigella sativa and its major ingredient, thymoquinone, ameliorates angiotensin II-induced hypertension in rats |
Thymoquinone | Memory Disorders | 4 | PM | 35718231 | 📋 | Effects of thymoquinone on scopolamine-induced spatial and echoic memory changes through regulation of lipid peroxidation and cholinergic impairment |
Thymoquinone | Memory Disorders | 2 | PM | 33325602 | 📋 | Evaluation of the effect of thymoquinone in d-galactose-induced memory impairments in rats: Role of MAPK, oxidative stress, and neuroinflammation pathways and telomere length |
Thymoquinone | Memory Disorders | 3 | PM | 32920292 | 📋 | Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta 1-42 infused rat model |
Thymoquinone | Memory Disorders | 1 | PM | 29662431 | 📋 | The Neuroprotective Effects of Thymoquinone: A Review |
Thymoquinone | Osteoarthritis | 1 | PM | 32793594 | 📋 | In vitro Evaluation of the Anti-inflammatory Effects of Thymoquinone in Osteoarthritis and in silico Analysis of Inter-Related Pathways in Age-Related Degenerative Diseases |
Thymoquinone | Oxidative Stress | 11 | PM | 36874614 | 📋 | Dietary Thymoquinone Alone or Combined with Swimming Exercise Protect against Microcystin-LR-Induced Oxidative Injury in Mice |
Thymoquinone | Oxidative Stress | 10 | PM | 36273456 | 📋 | The Effect of Thymoquinone on Oxidative Stress Parameters and Apolipoprotein E in Alzheimer Model in Rats |
Thymoquinone | Oxidative Stress | 9 | PM | 35472482 | 📋 | Therapeutic implications and clinical manifestations of thymoquinone |
Thymoquinone | Oxidative Stress | 8 | PM | 34309746 | 📋 | Reserpine-induced altered neuro-behavioral, biochemical and histopathological assessments prevent by enhanced antioxidant defence system of thymoquinone in mice |
Thymoquinone | Oxidative Stress | 2 | PM | 33519481 | 📋 | Thymoquinone Prevents Dopaminergic Neurodegeneration by Attenuating Oxidative Stress Via the Nrf2/ARE Pathway |
Thymoquinone | Oxidative Stress | 1 | PM | 33513819 | 📋 | Thymoquinone Protects Neurons in the Cerebellum of Rats through Mitigating Oxidative Stress and Inflammation Following High-Fat Diet Supplementation |
Thymoquinone | Oxidative Stress | 5 | PM | 32512788 | 📋 | Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection Against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied With Conversion of White to Beige Fat in Mice |
Thymoquinone | Oxidative Stress | 6 | PM | 30211134 | 📋 | Effects of Nigella sativa Extracts on the Lipid Profile and Uncoupling Protein-1 Gene Expression in Brown Adipose Tissue of Mice |
Thymoquinone | Oxidative Stress | 4 | PM | 26823946 | 📋 | Modulation of Hydrogen Peroxide-Induced Oxidative Stress in Human Neuronal Cells by Thymoquinone-Rich Fraction and Thymoquinone via Transcriptomic Regulation of Antioxidant and Apoptotic Signaling Genes |
Thymoquinone | Oxidative Stress | 7 | PM | 20373678 | 📋 | Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide |
Thymoquinone | Oxidative Stress | 3 | PM | 19684436 | 📋 | Effects of Nigella sativa oil and thymoquinone on oxidative stress and neuropathy in streptozotocin-induced diabetic rats |
Thymoquinone | Parkinson's Disease | 3 | PM | 38660812 | 📋 | Thymoquinone ameliorates symptoms of Parkinson's disease in a 6-OHDA rat model by downregulation of miR-204-3p |
Thymoquinone | Parkinson's Disease | 1 | PM | 33519481 | 📋 | Thymoquinone Prevents Dopaminergic Neurodegeneration by Attenuating Oxidative Stress Via the Nrf2/ARE Pathway |
Thymoquinone | Parkinson's Disease | 2 | PM | 33402092 | 📋 | The mechanistic role of thymoquinone in Parkinson's disease: focus on neuroprotection in pre-clinical studies |
Thymoquinone | Postmenopausal Disorders | 1 | PM | 27247926 | 📋 | Effect of Nigella sativa on reproductive system in experimental menopause rat model |
Thymoquinone | Skin Photo Damage | 1 | PM | 33857815 | 📋 | Thymoquinone, extract from Nigella sativa seeds, protects human skin keratinocytes against UVA-irradiated oxidative stress, inflammation and mitochondrial dysfunction |