| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Senolytics | Age-Related Cognitive Decline | 1 | PM | 35042834 | 📋 | Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile |
| Senolytics | Age-Related Diseases | 7 | PM | 37880106 | 📋 | Potential Clinical Implications of Senotherapies for Cardiovascular Disease |
| Senolytics | Age-Related Diseases | 6 | PM | 37731189 | 📋 | Senescent cells at the crossroads of aging, disease, and tissue homeostasis |
| Senolytics | Age-Related Diseases | 5 | PM | 37191645 | 📋 | Recent Advances in Senolysis for Age-related Diseases |
| Senolytics | Age-Related Diseases | 4 | PM | 35953721 | 📋 | Cellular senescence and senolytics: the path to the clinic |
| Senolytics | Age-Related Diseases | 3 | PM | 35912854 | 📋 | Cellular senescence: a key therapeutic target in aging and diseases |
| Senolytics | Age-Related Diseases | 2 | PM | 35292270 | 📋 | Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans |
| Senolytics | Age-Related Diseases | 1 | PM | 32854855 | 📋 | Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases |
| Senolytics | Aging | 15 | PM | 38339070 | 📋 | Senotherapeutics to Counteract Senescent Cells Are Prominent Topics in the Context of Anti-Ageing Strategies |
| Senolytics | Aging | 14 | PM | 38203812 | 📋 | Eternal Youth: A Comprehensive Exploration of Gene, Cellular, and Pharmacological Anti-Aging Strategies |
| Senolytics | Aging | 13 | PM | 37424179 | 📋 | NAD metabolism: Role in senescence regulation and aging |
| Senolytics | Aging | 12 | PM | 36980256 | 📋 | Emerging Therapeutic Approaches to Target the Dark Side of Senescent Cells: New Hopes to Treat Aging as a Disease and to Delay Age-Related Pathologies |
| Senolytics | Aging | 11 | PM | 36555859 | 📋 | Mitochondrial Aging and Senolytic Natural Products with Protective Potential |
| Senolytics | Aging | 10 | PM | 36170432 | 📋 | Targeting Cellular Senescence for Age-Related Diseases: Path to Clinical Translation |
| Senolytics | Aging | 9 | PM | 36170430 | 📋 | Cellular Senescence in Aging, Tissue Repair, and Regeneration |
| Senolytics | Aging | 8 | PM | 36159455 | 📋 | Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging - from theory to practice |
| Senolytics | Aging | 7 | PM | 35968789 | 📋 | Metabolic changes in aging humans: current evidence and therapeutic strategies |
| Senolytics | Aging | 6 | PM | 35912854 | 📋 | Cellular senescence: a key therapeutic target in aging and diseases |
| Senolytics | Aging | 5 | PM | 35821824 | 📋 | Cellular Senescence and Ageing: Mechanisms and Interventions |
| Senolytics | Aging | 4 | PM | 35674055 | 📋 | Targeting cellular senescence to combat cancer and aging |
| Senolytics | Aging | 3 | PM | 35269453 | 📋 | Synergistic Anti-Ageing through Senescent Cells Specific Reprogramming |
| Senolytics | Aging | 1 | PM | 34720589 | 📋 | NAD +, Senolytics, or Pyruvate for Healthy Aging? |
| Senolytics | Aging | 2 | PM | 32854855 | 📋 | Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases |
| Senolytics | Aging Brain | 4 | PM | 38076538 | 📋 | Cellular senescence in brain aging and cognitive decline |
| Senolytics | Aging Brain | 3 | PM | 38030088 | 📋 | Cellular senescence in brain aging and neurodegeneration |
| Senolytics | Aging Brain | 2 | PM | 36167854 | 📋 | Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance |
| Senolytics | Aging Brain | 1 | PM | 35430158 | 📋 | Cellular senescence in the Aging Brain: A promising target for neurodegenerative diseases |
| Senolytics | Aging Kidney | 1 | PM | 36384564 | 📋 | The diseased kidney: aging and senescent immunology |
| Senolytics | Aging Muscle Function Decline | 1 | PM | 37335024 | 📋 | The life and times of cellular senescence in skeletal muscle: friend or foe for homeostasis and adaptation? |
| Senolytics | Aging Skin | 4 | PM | 38074322 | 📋 | The role of cellular senescence in skin aging and age-related skin pathologies |
| Senolytics | Aging Skin | 3 | PM | 36830002 | 📋 | Hallmarks and Biomarkers of Skin Senescence: An Updated Review of Skin Senotherapeutics |
| Senolytics | Aging Skin | 2 | PM | 36170431 | 📋 | Targeting Cellular Senescence with Senotherapeutics: Development of New Approaches for Skin Care |
| Senolytics | Aging Skin | 1 | PM | 35274377 | 📋 | Attenuation of intrinsic aging of the skin via elimination of senescent dermal fibroblasts with senolytic drugs |
| Senolytics | Alzheimer's Disease | 2 | PM | 37874084 | 📋 | Translating the Biology of Aging into New Therapeutics for Alzheimer's Disease: Senolytics |
| Senolytics | Alzheimer's Disease | 1 | PM | 37162971 | 📋 | Senolytic therapy to modulate the progression of Alzheimer's Disease (SToMP-AD) - Outcomes from the first clinical trial of senolytic therapy for Alzheimer's disease |
| Senolytics | Cellular Senescence | 4 | PM | 36170430 | 📋 | Cellular Senescence in Aging, Tissue Repair, and Regeneration |
| Senolytics | Cellular Senescence | 3 | PM | 35821852 | 📋 | Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models |
| Senolytics | Cellular Senescence | 2 | PM | 35821824 | 📋 | Cellular Senescence and Ageing: Mechanisms and Interventions |
| Senolytics | Cellular Senescence | 1 | PM | 35269453 | 📋 | Synergistic Anti-Ageing through Senescent Cells Specific Reprogramming |
| Senolytics | Hypertension | 1 | PM | 35554866 | 📋 | Elimination of Senescent Cells Attenuates Obesity-Induced Increase in Sympathetic Nerve Activity |
| Senolytics | Immunosenescence | 2 | PM | 37886012 | 📋 | Impact of senolytic treatment on immunity, aging, and disease |
| Senolytics | Immunosenescence | 1 | PM | 37255929 | 📋 | The ageing immune system as a potential target of senolytics |
| Senolytics | Longevity | 1 | PM | 36699942 | 📋 | Targeting senescent cells for a healthier longevity: the roadmap for an era of global aging |
| Senolytics | Mitochondrial Decay | 1 | PM | 36555859 | 📋 | Mitochondrial Aging and Senolytic Natural Products with Protective Potential |
| Senolytics | Muscle Atrophy | 1 | PM | 37468473 | 📋 | Clearance of defective muscle stem cells by senolytics restores myogenesis in myotonic dystrophy type 1 |
| Senolytics | Osteoarthritis | 6 | PM | 38494091 | 📋 | Senolytic therapeutics: An emerging treatment modality for osteoarthritis |
| Senolytics | Osteoarthritis | 5 | PM | 38287696 | 📋 | Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging |
| Senolytics | Osteoarthritis | 4 | PM | 38015122 | 📋 | Senescence in Osteoarthritis: Overview of Mechanisms and Therapeutics |
| Senolytics | Osteoarthritis | 3 | PM | 35951358 | 📋 | Senolytic drugs relieve pain by reducing peripheral nociceptive signaling without modifying joint tissue damage in spontaneous osteoarthritis |
| Senolytics | Osteoarthritis | 2 | PM | 35658936 | 📋 | Clearance of senescent cells with ABT-263 improves biological functions of synovial mesenchymal stem cells from osteoarthritis patients |
| Senolytics | Osteoarthritis | 1 | PM | 35447516 | 📋 | Targeting cellular senescence as a novel treatment for osteoarthritis |
| Senolytics | Osteoporosis | 1 | PM | 35439699 | 📋 | Salubrinal-mediated activation of eIF2α signaling improves oxidative stress-induced BMSCs senescence and senile osteoporosis |
| Senolytics | Parkinson's Disease | 2 | PM | 37840914 | 📋 | Senolytic and senomorphic secondary metabolites as therapeutic agents in Drosophila melanogaster models of Parkinson's disease |
| Senolytics | Parkinson's Disease | 1 | PM | 35516803 | 📋 | Neuroglial Senescence, α-Synucleinopathy, and the Therapeutic Potential of Senolytics in Parkinson's Disease |
| Senolytics | Skin Photo Damage | 1 | PM | 35489284 | 📋 | Inhibition of matrix metalloproteinase expression by selective clearing of senescent dermal fibroblasts attenuates ultraviolet-induced photoaging |
| Senolytics | Vascular Aging | 2 | PM | 37593877 | 📋 | Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment |
| Senolytics | Vascular Aging | 1 | PM | 37511296 | 📋 | Vascular Ageing: Mechanisms, Risk Factors, and Treatment Strategies |
