Substance | Condition | Seq | Src | PMID | Dtl | Title |
Oleuropein | Age-Related Cognitive Decline | 1 | PM | 31754302 | 📋 | Effect Of An Extra-Virgin Olive Oil Intake On The Delay Of Cognitive Decline: Role Of Secoiridoid Oleuropein? |
Oleuropein | Age-Related Diseases | 1 | PM | 37049607 | 📋 | Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota |
Oleuropein | Age-Related Diseases | 2 | PM | 29765503 | 📋 | Oleuropein Aglycone Protects against MAO-A-Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB |
Oleuropein | Aging Brain | 1 | PM | 24375158 | 📋 | Antioxidant role of oleuropein on midbrain and dopaminergic neurons of substantia nigra in aged rats |
Oleuropein | Alzheimer's Disease | 4 | PM | 35310529 | 📋 | Olive polyphenols and bioavailable glutathione: Promising results in patients diagnosed with mild Alzheimer's disease |
Oleuropein | Alzheimer's Disease | 3 | PM | 35263086 | 📋 | Oleuropein-Rich Olive Leaf Extract Attenuates Neuroinflammation in the Alzheimer's Disease Mouse Model |
Oleuropein | Alzheimer's Disease | 1 | PM | 30995514 | 📋 | Oleuropein aglycone and hydroxytyrosol interfere differently with toxic Aβ 1-42 aggregation |
Oleuropein | Alzheimer's Disease | 2 | PM | 29675133 | 📋 | Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy |
Oleuropein | Alzheimer's Disease | 7 | PM | 23951225 | 📋 | The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology |
Oleuropein | Alzheimer's Disease | 6 | PM | 23520540 | 📋 | Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit |
Oleuropein | Alzheimer's Disease | 5 | PM | 23053546 | 📋 | Oleuropein, an anti-oxidant polyphenol constituent of olive promotes α-secretase cleavage of the amyloid precursor protein (AβPP) |
Oleuropein | Cellular Senescence | 2 | PM | 38845370 | 📋 | Multiple-heated cooking oil promotes early hepatic and renal senescence in adult male rats: The potential regenerative capacity of oleuropein |
Oleuropein | Cellular Senescence | 1 | PM | 32745074 | 📋 | Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis |
Oleuropein | Genotoxicity | 1 | PM | 32697745 | 📋 | Protective effects of olive oil phenolics oleuropein and hydroxytyrosol against hydrogen peroxide-induced DNA damage in human peripheral lymphocytes |
Oleuropein | Healthspan | 1 | PM | 32276415 | 📋 | Healthspan Maintenance and Prevention of Parkinson's-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans |
Oleuropein | Hypertension | 3 | PM | 28347166 | 📋 | Oleuropein improves glucose tolerance and lipid profile in rats with simultaneous renovascular hypertension and type 2 diabetes |
Oleuropein | Hypertension | 2 | PM | 27847271 | 📋 | Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats |
Oleuropein | Hypertension | 1 | PM | 26951205 | 📋 | Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial |
Oleuropein | Longevity | 1 | PM | 34829568 | 📋 | Oleuropein Enhances Stress Resistance and Extends Lifespan via Insulin/IGF-1 and SKN-1/Nrf2 Signaling Pathway in Caenorhabditis elegans |
Oleuropein | Osteoarthritis | 3 | PM | 36982904 | 📋 | NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol |
Oleuropein | Osteoarthritis | 1 | PM | 33010113 | 📋 | TRL4, RAGE and p-JNK/JNK mediated inflammatory aggression in osteoathritic human chondrocytes are counteracted by redox-sensitive phenolic olive compounds: Comparison with ibuprofen |
Oleuropein | Osteoarthritis | 2 | PM | 32745074 | 📋 | Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis |
Oleuropein | Osteoarthritis | 4 | PM | 28952621 | 📋 | Oleuropein inhibits the IL-1β-induced expression of inflammatory mediators by suppressing the activation of NF-κB and MAPKs in human osteoarthritis chondrocytes |
Oleuropein | Osteoporosis | 1 | PM | 20495905 | 📋 | Oleuropein enhances osteoblastogenesis and inhibits adipogenesis: the effect on differentiation in stem cells derived from bone marrow |
Oleuropein | Oxidative Stress | 2 | PM | 20335636 | 📋 | Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats |
Oleuropein | Oxidative Stress | 1 | PM | 19725535 | 📋 | Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats |
Oleuropein | Parkinson's Disease | 2 | PM | 36774383 | 📋 | Oleuropein confers neuroprotection against rotenone-induced model of Parkinson's disease via BDNF/CREB/Akt pathway |
Oleuropein | Parkinson's Disease | 1 | PM | 30147420 | 📋 | Oleuropein and Rutin Protect Against 6-OHDA-induced Neurotoxicity in PC12 Cells Through Modulation of Mitochondrial Function and Unfolded Protein Response |
Oleuropein | Parkinson's Disease | 4 | PM | 29844450 | 📋 | Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates |
Oleuropein | Parkinson's Disease | 3 | PM | 23394606 | 📋 | Inhibition of 6-hydroxydopamine-induced PC12 cell apoptosis by olive (Olea europaea L.) leaf extract is performed by its main component oleuropein |
Oleuropein | Postmenopausal Osteoporosis | 1 | PM | 36060661 | 📋 | Efficacy and Mechanisms of Oleuropein in Postmenopausal Osteoporosis |
Oleuropein | Postmenopausal Osteoporosis | 2 | PM | 21539839 | 📋 | Olive polyphenol hydroxytyrosol prevents bone loss |
Oleuropein | Skin Photo Damage | 1 | PM | 30884286 | 📋 | Photoprotection assessment of olive (Olea europaea L.) leaves extract standardized to oleuropein: In vitro and in silico approach for improved sunscreens |
Oleuropein | Skin Photo Damage | 2 | PM | 19957248 | 📋 | Effects of olive leaf extract and its main component oleuroepin on acute ultraviolet B irradiation-induced skin changes in C57BL/6J mice |
Oleuropein | Stroke | 1 | PM | 32922228 | 📋 | Oleuropein Improved Post Cerebral Stroke Cognitive Function by Promoting Histone Acetylation and Phosphorylation of cAMP Response Element-Binding Protein in MCAO Rats |