| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Irisin | Aging Muscle Function Decline | 1 | PM | 36539073 | 📋 | Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway |
| Irisin | Alzheimer's Disease | 4 | PM | 38993140 | 📋 | Therapeutic potential of exercise-hormone irisin in Alzheimer's disease |
| Irisin | Alzheimer's Disease | 3 | PM | 38658376 | 📋 | Research progress on the regulatory mechanisms of Irisin on cognitive dysfunction in patients with Alzheimer's disease and the interventional role of Irisin in associated diseases |
| Irisin | Alzheimer's Disease | 2 | PM | 37689059 | 📋 | Irisin reduces amyloid-β by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling |
| Irisin | Alzheimer's Disease | 1 | PM | 37569815 | 📋 | Move Your Body toward Healthy Aging: Potential Neuroprotective Mechanisms of Irisin in Alzheimer's Disease |
| Irisin | Muscle Atrophy | 2 | PM | 38581552 | 📋 | Irisin alters D-galactose-induced apoptosis by increasing caveolin-1 expression in C2C12 myoblasts and skeletal muscle fibroblasts |
| Irisin | Muscle Atrophy | 1 | PM | 37717561 | 📋 | Irisin ameliorated skeletal muscle atrophy by inhibiting fatty acid oxidation and pyroptosis induced by palmitic acid in chronic kidney disease |
| Irisin | Osteoarthritis | 1 | PM | 36982198 | 📋 | The Role of Lubricin, Irisin and Exercise in the Prevention and Treatment of Osteoarthritis |
| Irisin | Osteoporosis | 3 | PM | 39175571 | 📋 | The association between circulating irisin levels and osteoporosis in women: a systematic review and meta-analysis of observational studies |
| Irisin | Osteoporosis | 2 | PM | 38626873 | 📋 | Irisin alleviates obesity-induced bone loss by inhibiting interleukin 6 expression via TLR4/MyD88/NF-κB axis in adipocytes |
| Irisin | Osteoporosis | 1 | PM | 37669714 | 📋 | Irisin as an agent for protecting against osteoporosis: A review of the current mechanisms and pathways |
| Irisin | Parkinson's Disease | 2 | PM | 38134742 | 📋 | Relationship of irisin with disease severity and dopamine uptake in Parkinson's disease patients |
| Irisin | Parkinson's Disease | 1 | PM | 36720890 | 📋 | Irisin exhibits neuroprotection by preventing mitochondrial damage in Parkinson's disease |
| Irisin | Postmenopausal Osteoporosis | 3 | PM | 38672282 | 📋 | Irisin and Its Role in Postmenopausal Osteoporosis and Sarcopenia |
| Irisin | Postmenopausal Osteoporosis | 2 | PM | 37373043 | 📋 | Irisin Protects against Loss of Trabecular Bone Mass and Strength in Adult Ovariectomized Mice by Stimulating Osteoblast Activity |
| Irisin | Postmenopausal Osteoporosis | 1 | PM | 36852814 | 📋 | Serum Irisin is Associated With Bone Mineral Density in Postmenopausal T2dm Patients Complicated With Osteoporosis and in Mice With Diabetic Osteoporosis |
| Irisin | Sarcopenia | 3 | PM | 38672282 | 📋 | Irisin and Its Role in Postmenopausal Osteoporosis and Sarcopenia |
| Irisin | Sarcopenia | 2 | PM | 36539073 | 📋 | Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway |
| Irisin | Sarcopenia | 1 | PM | 36510115 | 📋 | Irisin ameliorates age-associated sarcopenia and metabolic dysfunction |
| Irisin | Vascular Aging | 1 | PM | 38029393 | 📋 | Irisin: A Potentially Fresh Insight into the Molecular Mechanisms Underlying Vascular Aging |
