Substance | Condition | Seq | Src | PMID | Dtl | Title |
Ginkgolides | Aging Muscle Function Decline | 1 | PM | 37076950 | 📋 | Ginkgolide B facilitates muscle regeneration via rejuvenating osteocalcin-mediated bone-to-muscle modulation in aged mice |
Ginkgolides | Alzheimer's Disease | 17 | PM | 38676673 | 📋 | [Ginkgolide B: mechanisms of neurobiological effects, prospects for use in the therapy of Alzheimer's disease] |
Ginkgolides | Alzheimer's Disease | 16 | PM | 37793010 | 📋 | Ginkgolide attenuates memory impairment and neuroinflammation by suppressing the NLRP3/caspase-1 pathway in Alzheimer's disease |
Ginkgolides | Alzheimer's Disease | 10 | PM | 36992579 | 📋 | Quantitative Proteomics Reveals Neuroprotective Mechanism of Ginkgolide B in Aβ1-42-induced N2a Neuroblastoma Cells |
Ginkgolides | Alzheimer's Disease | 9 | PM | 35607377 | 📋 | Effect of ginkgolide K on calcium channel activity in Alzheimer's disease |
Ginkgolides | Alzheimer's Disease | 8 | PM | 35384262 | 📋 | Ginkgolides and Huperzine A for complementary treatment of Alzheimer's disease |
Ginkgolides | Alzheimer's Disease | 5 | PM | 35129804 | 📋 | Protective Effects of Ginkgolide on a Cellular Model of Alzheimer's Disease via Suppression of the NF-κB Signaling Pathway |
Ginkgolides | Alzheimer's Disease | 7 | PM | 35050445 | 📋 | Ginkgolide B inactivates the NLRP3 inflammasome by promoting autophagic degradation to improve learning and memory impairment in Alzheimer's disease |
Ginkgolides | Alzheimer's Disease | 1 | PM | 34633804 | 📋 | Protective Effect of Ginkgolide B against Cognitive Impairment in Mice via Regulation of Gut Microbiota |
Ginkgolides | Alzheimer's Disease | 6 | PM | 34478813 | 📋 | Ginkgolide B inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization in Aβ 1-42-induced microglia cells |
Ginkgolides | Alzheimer's Disease | 2 | PM | 34332327 | 📋 | Ginkgolide B protects against cognitive impairment in senescence-accelerated P8 mice by mitigating oxidative stress, inflammation and ferroptosis |
Ginkgolides | Alzheimer's Disease | 3 | PM | 33880582 | 📋 | Ginkgolide B‑induced AMPK pathway activation protects astrocytes by regulating endoplasmic reticulum stress, oxidative stress and energy metabolism induced by Aβ1‑42 |
Ginkgolides | Alzheimer's Disease | 15 | PM | 30541279 | 📋 | Ginkgolide A Prevents the Amyloid-β-Induced Depolarization of Cortical Neurons |
Ginkgolides | Alzheimer's Disease | 13 | PM | 30010136 | 📋 | Ginkgo biloba Extract EGb 761 and Its Specific Components Elicit Protective Protein Clearance Through the Autophagy-Lysosomal Pathway in Tau-Transgenic Mice and Cultured Neurons |
Ginkgolides | Alzheimer's Disease | 14 | PM | 28234255 | 📋 | Phytochemical Ginkgolide B Attenuates Amyloid-β1-42 Induced Oxidative Damage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells |
Ginkgolides | Alzheimer's Disease | 4 | PM | 25677400 | 📋 | Ginkgolide B revamps neuroprotective role of apurinic/apyrimidinic endonuclease 1 and mitochondrial oxidative phosphorylation against Aβ25-35 -induced neurotoxicity in human neuroblastoma cells |
Ginkgolides | Alzheimer's Disease | 12 | PM | 22700047 | 📋 | Effects of ginkgolide A on okadaic acid-induced tau hyperphosphorylation and the PI3K-Akt signaling pathway in N2a cells |
Ginkgolides | Alzheimer's Disease | 11 | PM | 20709055 | 📋 | Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25-35 partly via up-regulation of brain-derived neurotrophic factor |
Ginkgolides | Hypertension | 1 | PM | 31739841 | 📋 | Ginkgolide A protects adverse cardiac remodeling through enhancing antioxidation and nitric oxide utilization in mice with pressure overload |
Ginkgolides | Osteoarthritis | 4 | PM | 38346525 | 📋 | Ginkgolide C inhibits ROS-mediated activation of NLRP3 inflammasome in chondrocytes to ameliorate osteoarthritis |
Ginkgolides | Osteoarthritis | 3 | PM | 37527970 | 📋 | Ginkgolide K delays the progression of osteoarthritis by regulating YAP to promote the formation of cartilage extracellular matrix |
Ginkgolides | Osteoarthritis | 1 | PM | 36386227 | 📋 | Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway |
Ginkgolides | Osteoarthritis | 2 | PM | 29905408 | 📋 | Ginkgolide B exerts anti-inflammatory and chondroprotective activity in LPS-induced chondrocytes |
Ginkgolides | Osteoporosis | 1 | PM | 33781894 | 📋 | Ginkgolide B monotherapy reverses osteoporosis by regulating oxidative stress-mediated bone homeostasis |
Ginkgolides | Osteoporosis | 2 | PM | 31225702 | 📋 | Ginkgolide B promotes osteoblast differentiation via activation of canonical Wnt signalling and alleviates osteoporosis through a bone anabolic way |
Ginkgolides | Oxidative Stress | 2 | PM | 36830083 | 📋 | Radical Scavenging Potential of Ginkgolides and Bilobalide: Insight from Molecular Modeling |
Ginkgolides | Oxidative Stress | 1 | PM | 25677400 | 📋 | Ginkgolide B revamps neuroprotective role of apurinic/apyrimidinic endonuclease 1 and mitochondrial oxidative phosphorylation against Aβ25-35 -induced neurotoxicity in human neuroblastoma cells |
Ginkgolides | Parkinson's Disease | 3 | PM | 36863713 | 📋 | Ginkgolide A improves the pleiotropic function and reinforces the neuroprotective effects by mesenchymal stem cell-derived exosomes in 6-OHDA-induced cell model of Parkinson's disease |
Ginkgolides | Parkinson's Disease | 2 | PM | 35121334 | 📋 | The neuroprotective effects and transdifferentiation of astrocytes into dopaminergic neurons of Ginkgolide K on Parkinson' disease mice |
Ginkgolides | Parkinson's Disease | 1 | PM | 32878312 | 📋 | Synergistic Effects of Ginkgolide B and Protocatechuic Acid on the Treatment of Parkinson's Disease |
Ginkgolides | Parkinson's Disease | 4 | PM | 31165943 | 📋 | Enhancing the Astrocytic Clearance of Extracellular α-Synuclein Aggregates by Ginkgolides Attenuates Neural Cell Injury |
Ginkgolides | Parkinson's Disease | 5 | PM | 29214369 | 📋 | Ginkgolide K promotes the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells |
Ginkgolides | Stroke | 2 | PM | 31691373 | 📋 | Ginkgolide B protects human pulmonary alveolar epithelial A549 cells from lipopolysaccharide-induced inflammatory responses by reducing TRIM37-mediated NF-κB activation |
Ginkgolides | Stroke | 1 | PM | 26059355 | 📋 | Neuroprotective Effects of Ginkgolide B Against Ischemic Stroke: A Review of Current Literature |