| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Docosahexaenoic Acid | Age-Related Cognitive Decline | 5 | PM | 35866081 | 📋 | A Dietary Supplement Containing Micronutrients, Phosphatidylserine, and Docosahexaenoic Acid Counteracts Cognitive Impairment in D-Galactose-Induced Aged Rats |
| Docosahexaenoic Acid | Age-Related Cognitive Decline | 4 | PM | 35704085 | 📋 | DHA status influences effects of B-vitamin supplementation on cognitive ageing: a post-hoc analysis of the B-proof trial |
| Docosahexaenoic Acid | Age-Related Cognitive Decline | 3 | PM | 35618634 | 📋 | Docosahexaenoic acid enhances hippocampal insulin sensitivity to promote cognitive function of aged rats on a high-fat diet |
| Docosahexaenoic Acid | Age-Related Cognitive Decline | 1 | PM | 32856190 | 📋 | Effect of folic acid combined with docosahexaenoic acid intervention on mild cognitive impairment in elderly: a randomized double-blind, placebo-controlled trial |
| Docosahexaenoic Acid | Age-Related Cognitive Decline | 2 | PM | 26901223 | 📋 | Docosahexaenoic Acid and Cognition throughout the Lifespan |
| Docosahexaenoic Acid | Age-Related Macular Degeneration | 4 | PM | 38745035 | 📋 | Association between dietary consumption of fatty acids and age-related macular degeneration in the National Health and Nutrition Examination Survey |
| Docosahexaenoic Acid | Age-Related Macular Degeneration | 3 | PM | 35388706 | 📋 | Dietary omega-3 LCPUFA intake in the prevention of neovascular age-related macular degeneration: a systematic review and meta-analysis |
| Docosahexaenoic Acid | Age-Related Macular Degeneration | 2 | PM | 35271555 | 📋 | Association of plasma ω-3 fatty acids with early age-related macular degeneration in the Multi-Ethnic Study of Atherosclerosis (MESA) |
| Docosahexaenoic Acid | Age-Related Macular Degeneration | 1 | PM | 32711865 | 📋 | Nutrition and the aging retina: A comprehensive review of the relationship between nutrients and their role in age-related macular degeneration and retina disease prevention |
| Docosahexaenoic Acid | Aging | 3 | PM | 36859557 | 📋 | Long-term dietary DHA intervention prevents telomere attrition and lipid disturbance in telomerase-deficient male mice |
| Docosahexaenoic Acid | Aging | 2 | PM | 36348794 | 📋 | Gut microbiome and metabolome analyses reveal the protective effect of special high-docosahexaenoic acid tuna oil on d-galactose-induced aging in mice |
| Docosahexaenoic Acid | Aging | 1 | PM | 33911955 | 📋 | Efficacy of choline and DHA supplements or enriched environment exposure during early adult obesity in mitigating its adverse impact through aging in rats |
| Docosahexaenoic Acid | Aging Brain | 2 | PM | 37759879 | 📋 | Omega-3 Fatty Acids, Cognition, and Brain Volume in Older Adults |
| Docosahexaenoic Acid | Aging Brain | 1 | PM | 34205196 | 📋 | DHA and Its Elaborated Modulation of Antioxidant Defenses of the Brain: Implications in Aging and AD Neurodegeneration |
| Docosahexaenoic Acid | Aging Muscle Function Decline | 1 | PM | 33781784 | 📋 | Effects of n-3 EPA and DHA supplementation on fat free mass and physical performance in elderly. A systematic review and meta-analysis of randomized clinical trial |
| Docosahexaenoic Acid | Alzheimer's Disease | 18 | PM | 38373507 | 📋 | N-3 polyunsaturated fatty acids attenuate amyloid-beta-induced toxicity in AD transgenic Caenorhabditis elegans via promotion of proteasomal activity and activation of PPAR-gamma |
| Docosahexaenoic Acid | Alzheimer's Disease | 17 | PM | 37836528 | 📋 | Supplementation of Medium-Chain Triglycerides Combined with Docosahexaenoic Acid Inhibits Amyloid Beta Protein Deposition by Improving Brain Glucose Metabolism in APP/PS1 Mice |
| Docosahexaenoic Acid | Alzheimer's Disease | 16 | PM | 36678710 | 📋 | Docosahexaenoic Acid Ameliorates Contextual Fear Memory Deficits in the Tg2576 Alzheimer's Disease Mouse Model: Cellular and Molecular Correlates |
| Docosahexaenoic Acid | Alzheimer's Disease | 15 | PM | 35782939 | 📋 | DHA Ameliorates Cognitive Ability, Reduces Amyloid Deposition, and Nerve Fiber Production in Alzheimer's Disease |
| Docosahexaenoic Acid | Alzheimer's Disease | 14 | PM | 35334816 | 📋 | Higher Serum DHA and Slower Cognitive Decline in Patients with Alzheimer's Disease: Two-Year Follow-Up |
| Docosahexaenoic Acid | Alzheimer's Disease | 13 | PM | 35250535 | 📋 | A Synergistic Combination of DHA, Luteolin, and Urolithin A Against Alzheimer's Disease |
| Docosahexaenoic Acid | Alzheimer's Disease | 12 | PM | 34769257 | 📋 | Why Have the Benefits of DHA Not Been Borne Out in the Treatment and Prevention of Alzheimer's Disease? A Narrative Review Focused on DHA Metabolism and Adipose Tissue |
| Docosahexaenoic Acid | Alzheimer's Disease | 11 | PM | 34205196 | 📋 | DHA and Its Elaborated Modulation of Antioxidant Defenses of the Brain: Implications in Aging and AD Neurodegeneration |
| Docosahexaenoic Acid | Alzheimer's Disease | 10 | PM | 34182090 | 📋 | Combination of docosahexaenoic acid and Ginko biloba extract improves cognitive function and hippocampal tissue damages in a mouse model of Alzheimer's disease |
| Docosahexaenoic Acid | Alzheimer's Disease | 9 | PM | 33733657 | 📋 | DHA intake relates to better cerebrovascular and neurodegeneration neuroimaging phenotypes in middle-aged adults at increased genetic risk of Alzheimer disease |
| Docosahexaenoic Acid | Alzheimer's Disease | 4 | PM | 33163896 | 📋 | Effects of a Nutritional Formulation Containing Caprylic and Capric Acid, Phosphatidylserine, and Docosahexaenoic Acid in Streptozotocin-Lesioned Rats |
| Docosahexaenoic Acid | Alzheimer's Disease | 3 | PM | 32806612 | 📋 | Alzheimer's Disease and Specialized Pro-Resolving Lipid Mediators: Do MaR1, RvD1, and NPD1 Show Promise for Prevention and Treatment? |
| Docosahexaenoic Acid | Alzheimer's Disease | 2 | PM | 32486013 | 📋 | Omega-3 Fatty Acid-Type Docosahexaenoic Acid Protects Against Aβ-Mediated Mitochondrial Deficits and Pathomechanisms in Alzheimer's Disease-Related Animal Model |
| Docosahexaenoic Acid | Alzheimer's Disease | 1 | PM | 29695154 | 📋 | Effects of Astaxanthin and Docosahexaenoic-Acid-Acylated Astaxanthin on Alzheimer's Disease in APP/PS1 Double-Transgenic Mice |
| Docosahexaenoic Acid | Alzheimer's Disease | 8 | PM | 27825512 | 📋 | The pleiotropic effects of omega-3 docosahexaenoic acid on the hallmarks of Alzheimer's disease |
| Docosahexaenoic Acid | Alzheimer's Disease | 6 | PM | 27532692 | 📋 | Association of Serum Docosahexaenoic Acid With Cerebral Amyloidosis |
| Docosahexaenoic Acid | Alzheimer's Disease | 5 | PM | 26606074 | 📋 | Protective Effects of Dietary Supplementation with a Combination of Nutrients in a Transgenic Mouse Model of Alzheimer's Disease |
| Docosahexaenoic Acid | Alzheimer's Disease | 7 | PM | 19686246 | 📋 | Mechanism of docosahexaenoic acid-induced inhibition of in vitro Abeta1-42 fibrillation and Abeta1-42-induced toxicity in SH-S5Y5 cells |
| Docosahexaenoic Acid | Hypertension | 1 | PM | 37051424 | 📋 | Investigating the Role of EPA and DHA on Cellular Oxidative Stress; Profiling Antidiabetic and Antihypertensive Potential |
| Docosahexaenoic Acid | Muscle Atrophy | 2 | PM | 34620362 | 📋 | Preventive effect of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) against endotoxin-induced muscle atrophy |
| Docosahexaenoic Acid | Muscle Atrophy | 1 | PM | 27239420 | 📋 | Docosahexaenoic acid-supplementation prior to fasting prevents muscle atrophy in mice |
| Docosahexaenoic Acid | Osteoarthritis | 1 | PM | 37450265 | 📋 | DHA attenuates cartilage degeneration by mediating apoptosis and autophagy in human chondrocytes and rat models of osteoarthritis |
| Docosahexaenoic Acid | Osteoporosis | 3 | PM | 35222712 | 📋 | Docosahexaenoic acid improves altered mineralization proteins, the decreased quality of hydroxyapatite crystals and suppresses oxidative stress induced by high glucose |
| Docosahexaenoic Acid | Osteoporosis | 1 | PM | 27836739 | 📋 | Docosahexaenoic acid signaling attenuates the proliferation and differentiation of bone marrow-derived osteoclast precursors and promotes apoptosis in mature osteoclasts |
| Docosahexaenoic Acid | Osteoporosis | 2 | PM | 17929247 | 📋 | Docosahexaenoic acid is more potent inhibitor of osteoclast differentiation in RAW 264.7 cells than eicosapentaenoic acid |
| Docosahexaenoic Acid | Oxidative Stress | 6 | PM | 37372014 | 📋 | Docosahexaenoic Acid as Master Regulator of Cellular Antioxidant Defenses: A Systematic Review |
| Docosahexaenoic Acid | Oxidative Stress | 5 | PM | 34118075 | 📋 | Synergistic effect of docosahexaenoic acid or conjugated linoleic acid with caffeic acid on ameliorating oxidative stress of HepG2 cells |
| Docosahexaenoic Acid | Oxidative Stress | 4 | PM | 33497204 | 📋 | Antioxidant Activity of Docosahexaenoic Acid (DHA) and Its Regulatory Roles in Mitochondria |
| Docosahexaenoic Acid | Oxidative Stress | 1 | PM | 33218112 | 📋 | Oxidative Stress in Endurance Cycling Is Reduced Dose-Dependently after One Month of Re-Esterified DHA Supplementation |
| Docosahexaenoic Acid | Oxidative Stress | 2 | PM | 25503390 | 📋 | Docosahexaenoic acid supplementation promotes erythrocyte antioxidant defense and reduces protein nitrosative damage in male athletes |
| Docosahexaenoic Acid | Oxidative Stress | 3 | PM | 16353135 | 📋 | Neuroblastoma cell death in response to docosahexaenoic acid: sensitization to chemotherapy and arsenic-induced oxidative stress |
| Docosahexaenoic Acid | Parkinson's Disease | 4 | PM | 38819068 | 📋 | Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson's disease |
| Docosahexaenoic Acid | Parkinson's Disease | 3 | PM | 33279658 | 📋 | Contribution of DHA diols (19,20-DHDP) produced by cytochrome P450s and soluble epoxide hydrolase to the beneficial effects of DHA supplementation in the brains of rotenone-induced rat models of Parkinson's disease |
| Docosahexaenoic Acid | Parkinson's Disease | 1 | PM | 32001239 | 📋 | Docosahexaenoic acid protects motor function and increases dopamine synthesis in a rat model of Parkinson's disease via mechanisms associated with increased protein kinase activity in the striatum |
| Docosahexaenoic Acid | Parkinson's Disease | 2 | PM | 28276272 | 📋 | Gut-brain and brain-gut axis in Parkinson's disease models: Effects of a uridine and fish oil diet |
| Docosahexaenoic Acid | Postmenopausal Disorders | 1 | PM | 32944877 | 📋 | Supplementation of fenugreek with choline-docosahexaenoic acid attenuates menopause induced memory loss, BDNF and dendritic arborization in ovariectomized rats |
| Docosahexaenoic Acid | Postmenopausal Osteoporosis | 1 | PM | 34464107 | 📋 | Comparative Study of DHA with Different Molecular Forms for Ameliorating Osteoporosis by Promoting Chondrocyte-to-Osteoblast Transdifferentiation in the Growth Plate of Ovariectomized Mice |
| Docosahexaenoic Acid | Sarcopenia | 1 | PM | 33759678 | 📋 | Effects of a Long Chain n-3 Polyunsaturated Fatty Acid-rich Multi-ingredient Nutrition Supplement on Body Composition and Physical Function in Older Adults with Low Skeletal Muscle Mass |
| Docosahexaenoic Acid | Sleep Quality | 1 | PM | 36235788 | 📋 | Effect of Docosahexaenoic Acid and Eicosapentaenoic Acid Supplementation on Sleep Quality in Healthy Subjects: A Randomized, Double-Blinded, Placebo-Controlled Trial |
| Docosahexaenoic Acid | Stroke | 1 | PM | 32964457 | 📋 | Dietary docosahexaenoic acid inhibits neurodegeneration and prevents stroke |
| Docosahexaenoic Acid | Telomere Dysfunction and Attrition | 2 | PM | 36859557 | 📋 | Long-term dietary DHA intervention prevents telomere attrition and lipid disturbance in telomerase-deficient male mice |
| Docosahexaenoic Acid | Telomere Dysfunction and Attrition | 1 | PM | 36130216 | 📋 | Association of omega-3 and omega-6 fatty acid intake with leukocyte telomere length in US males |
