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A 2016 review on the safety and toxicity of E. longifolia reported that it does not seem to have detrimental effects on sperm in test tubes when the scientists used it in therapeutic doses. However, animal studies show that in higher concentrations, it may be toxic.
The same review concluded that scientists consider E. longifolia safe as long as people do not take it in high doses. The authors recommend taking 200–400 milligrams daily with caution, especially if the person is an older adult.
People who have hormonal cancers should be cautious of taking E. longifolia, as it may increase testosterone levels. Although laboratory studies have indicated beneficial effects, these effects may not be the same in the human body.
People taking medications to lower their blood glucose should speak to their doctor before taking E. longifolia, as it may increase the effects of these medications.
According to the review, some sources advise people with certain conditions to avoid E. longifolia. These conditions include cancer, heart disease, and kidney disease. People with weakened immune systems should also be cautious. *
