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Sage is LIKELY SAFE in amounts typically used in foods. It is POSSIBLY SAFE when taken by mouth or applied to the skin in medicinal amounts, for up to 4 months.
However, sage is POSSIBLY UNSAFE when taken by mouth in high doses or for a long time. Some species of sage, such as common sage (Salvia officinalis), contain a chemical called thujone. Thujone can be poisonous if you take too much. This chemical can cause seizures and damage the liver and nervous system. The amount of thujone varies with the species of sage, the time of harvest, growing conditions, and other factors.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Taking sage during pregnancy is
LIKELY UNSAFE because of the possibility of consuming thujone, a chemical found in some sage. Thujone can bring on a woman's menstrual period, and this could cause a miscarriage. Avoid sage if you are breast-feeding, too. There is some evidence that thujone might reduce the supply of mother's milk.
Diabetes: Sage might lower blood sugar levels in people with diabetes. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use sage. The dose of your diabetes medications may need to be adjusted by your healthcare provider.
Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Spanish sage (Salvia lavandulaefolia) might have the same effects as the female hormone estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use Spanish sage.
High blood pressure, low blood pressure: Spanish sage (Salvia lavandulaefolia) might increase blood pressure in some people with high blood pressure. On the other hand, common sage (Salvia officinalis) might lower blood pressure in people with blood pressure that is already low. Be sure to monitor your blood pressure.
Seizure disorders: One species of sage (Salvia officinalis) contains significant amounts of thujone, a chemical that can trigger seizures. If you have a seizure disorder, don't take sage in amounts higher than those typically found in food.
Surgery: Common sage might affect blood sugar levels. There is a concern that it might interfere with blood sugar control during and after surgery. Stop using common sage as a medicine at least 2 weeks before a scheduled surgery.
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