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When taken by mouth: Safflower oil is LIKELY SAFE for most people when taken by mouth.
When applied to the skin: Safflower oil is POSSIBLY SAFE when applied to the skin.
When given by IV: Safflower oil is POSSIBLY SAFE when a specific safflower oil emulsion (Liposyn) is administered by a healthcare professional. Safflower yellow, a component of safflower flower, is POSSIBLY SAFE when administered by a healthcare professional.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Don't take safflower flower during pregnancy. Safflower flower is
LIKELY UNSAFE. It can bring on menstrual periods, make the uterus contract, and cause miscarriages.
There isn't enough reliable information to know if safflower oil or flower is safe to use when breast-feeding. Stay on the safe side and avoid use.
Children: Safflower oil is
POSSIBLY SAFE in children when a specific safflower oil emulsion (Liposyn) is administered IV (intravenously) by a healthcare professional. There isn't enough reliable information to know if safflower flower is safe for children or what the side effects might be.
Bleeding problems (hemorrhagic diseases, stomach or intestinal ulcers, or clotting disorders): Safflower can slow blood clotting and might increase the risk of bleeding in people with bleeding disorders.
Allergy to ragweed and related plants: Safflower may cause an allergic reaction in people who are sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking safflower.
Diabetes: Safflower oil might increase blood sugar. There is concern that safflower oil might interfere with blood sugar control in people with diabetes.
Surgery: Since safflower might slow blood clotting, there is a concern that it could increase the risk of bleeding during and after surgery. Stop using safflower at least 2 weeks before a scheduled surgery.
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