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The US Food and Drug Administration has established that rutin supplements are generally safe to use. In a small number of people, it may produce side effects such as light-headedness, nervousness, flushing, minor stomach upset, blurred vision, headache, rash, muscle stiffness and fluid accumulation in the knees.
A small number of people may be allergic to rutin. Symptoms of an allergic reaction may include hives, breathing difficulties, chest pain or swelling of the face, lips, tongue or throat. Report serious symptoms to a doctor as soon as possible.
People taking blood thinners or any other medication should speak to their doctors before taking rutin. Pregnant or nursing women shouldn’t take it, and it shouldn’t be used over the long term without a doctor’s approval. *