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When taken by mouth: Noni is POSSIBLY SAFE for most adults. Consuming dried noni fruit might cause some stomach discomfort. There are also several reports of liver damage in people who consumed noni tea or juice for several weeks. It isn't clear if noni was the cause of these side effects.
When applied to the skin: Noni is POSSIBLY SAFE for most adults when used in an ointment.
Pregnancy and breast-feeding: There isn’t enough reliable information to know if noni is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Kidney disease: Noni contains large amounts of potassium. This can be a problem, especially for people with kidney disease. Don't use noni in large amounts if you have kidney problems.
High potassium levels: Drinking noni fruit juice might increase potassium levels in the blood and make them too high, especially in people who already have high levels.
Liver disease: Noni has been linked to several cases of liver damage. Avoid using noni if you have liver disease.
Interactions
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Medications for high blood pressure (ACE inhibitors) interacts with NONI
Some medications for high blood pressure can increase potassium levels in the blood. Consuming noni juice along with these medications for high blood pressure might cause too much potassium in the blood.
Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others.
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Medications for high blood pressure (Angiotensin receptor blockers (ARBs)) interacts with NONI
Some medications for high blood pressure can increase potassium levels in the blood. Consuming noni juice along with these medications for high blood pressure might cause too much potassium to be in the blood.
Some medications for high blood pressure include losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), candesartan (Atacand), telmisartan (Micardis), eprosartan (Teveten), and others.
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Medications that can harm the liver (Hepatotoxic drugs) interacts with NONI
Noni might harm the liver. Taking noni along with medication that might also harm the liver can increase the risk of liver damage. Do not take noni if you are taking a medication that can harm the liver.
Some medications that can harm the liver include acetaminophen (Tylenol and others), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporanox), erythromycin (Erythrocin, Ilosone, others), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), and many others.
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Warfarin (Coumadin) interacts with NONI
Warfarin (Coumadin) is used to slow blood clotting. Taking noni juice might decrease how well warfarin (Coumadin) works to slow blood clotting. This could increase the chance of blood clotting.
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Water pills (Potassium-sparing diuretics) interacts with NONI
Noni contains large amounts of potassium. Some "water pills" can also increase potassium levels in the body. Taking some "water pills" along with noni might cause too much potassium to be in the body.
Some "water pills" that increase potassium in the body include amiloride (Midamor), spironolactone (Aldactone), and triamterene (Dyrenium). *
