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Excess Vitamin K
Excess of vitamin K can cause problems in people on blood-thinning medications like warfarin. Excess of lettuce may decrease the effectiveness of warfarin. Hence, if you are on blood-thinning medication, talk to your doctor before consuming lettuce.
Issues During Pregnancy And Breastfeeding
Lettuce is safe in normal amounts. But there is no information on what would happen if taken in excess. Hence, avoid excess intake.
Issues With Prostate And Vision (Wild Lettuce)
Wild lettuce is another variety of lettuce, but it is very less commonly consumed. It must not be taken during pregnancy and breastfeeding (it can lead to complications; more research is warranted). It also can lead to an enlarged prostate and narrow-angle glaucoma. Hence, avoid consuming it. More research is needed in this aspect, however. *
