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The most obvious downside of gallic acid is the lack of human research behind its use.
Gallic acid is best consumed through natural food sources, especially considering the lack of approved and well-studied supplements on the market.
That said, one dated animal study concluded that gallic acid is nontoxic up to a dose of 2.3 grams per pound (5 grams per kg) of body weight when taken by mouth.
Another animal study found that gallic acid given in doses of 0.4 mg per pound (0.9 grams per kg) of body weight per day for 28 days showed no signs of toxicity in mice.
Ultimately, further studies are needed to determine the best uses and dosages for humans. *
