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Collagen is a protein, individuals predisposed to kidney trouble like kidney stones should use caution when taking a collagen supplement. Consult a doctor to decide if a collagen supplement is safe for your situation. Collagen may also interfere with certain medications, ask your pharmacist for potential interactions.
Individuals with metabolic disorders may want to consult their doctor as well before adding collagen powder to their diet. Also, Individuals that are allergic to fish should be careful to avoid marine collagen.
However, The University of California study noted no adverse side effects associated with oral collagen. *