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Taking supplemental form of emodin in higher doses or using it for an extended duration of time can cause diarrhea. So the very purpose of using emodin may actually become a problem if it is not taken in the right amounts. Emodin can also negatively affect the digestive system and cause nausea, vomiting, and stomach upset. Taking emodin for prolonged duration can have a major impact on the health. For instance, chronic use can increase the risk of liver or kidney problems. So monitoring the function of these organs is necessary when taking emodin for an extended duration.
An important point to note here is that medical uses of emodin are not backed by the FDA. The medical advantages of emodin are lacking in extensive clinical research. So before taking emodin supplements for medical purposes, make sure you consult with your health care provider. *