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Most people taking DMAE do not experience side-effects. However, isolated adverse reactions have cropped up in different studies. Drowsiness, confusion, and high blood pressure have occurred in people with Alzheimer's who were taking this supplement, particularly when high doses were used. DMAE can be over-stimulating for some people. Headaches, irritability, and tense muscles may result, including tightness in the jaw, neck, or shoulders. Weight loss and insomnia may also occur. Lucid dreams have also been reported. These effects should disappear when intake is lowered or stopped.
At the time of writing, there were no well-known drug interactions with DMAE.
DMAE should not be used by epileptics or those with bipolar disorder (manic depression). Maximum safe dosages for children or for pregnant or nursing mothers have not been established.
If you have kidney or liver disease, consult your doctor before taking DMAE. These conditions can affect levels of the supplement in your body. *