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When taken by mouth: Coenzyme Q10 is LIKELY SAFE for most adults. While most people tolerate coenzyme Q10 well, it can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, and diarrhea. It can cause allergic skin rashes in some people. It also might lower blood pressure, so check your blood pressure carefully if you have very low blood pressure. Dividing the total daily dose by taking smaller amounts two or three times daily instead of a large amount all at once can help reduce side effects.
When applied to the skin: Coenzyme Q10 is LIKELY SAFE for most adults when applied directly to the gums.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Coenzyme Q10 is
POSSIBLY SAFE when taken by mouth appropriately during pregnancy. Coenzyme Q10 has been used safely when taken twice daily starting at 20 weeks until delivery. Not enough is known about the use of coenzyme Q10 during breast-feeding. Stay on the safe side and avoid use.
Children: Coenzyme Q10 is
POSSIBLY SAFE for children when taken by mouth. However, coenzyme Q10 should not be used in children without medical supervision.
Chemotherapy: People undergoing chemotherapy with a class of drugs called alkylating agents should use coenzyme Q10 with caution. There is some concern that coenzyme Q10 might lower the effectiveness of these drugs. Some alkylating agents include busulfan, carboplatin, cisplatin, cyclophosphamide (Cytoxan), dacarbazine, thiotepa, and many others.
High blood pressure or low blood pressure: Coenzyme Q10 might lower blood pressure. It can increase the effects of medications used to lower blood pressure. Discuss your use of coenzyme Q10 with your healthcare provider if you have blood pressure problems.
Smoking: Cigarette smoking depletes the amount of coenzyme Q10 stored by the body.
Surgery: Coenzyme Q10 might interfere with blood pressure control during and after surgery. Stop using coenzyme Q10 at least two weeks before a scheduled surgery.
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