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Allergy to green coffee bean extract, the natural source of chlorogenic acid, has been reported. Symptoms were primarily asthma attacks. However, coffee compounds other than chlorogenic acid seem to be responsible for this effec.
Because green coffee bean extract contains caffeine, it may cause some of its unwanted effects. You may want to avoid it late in the evening to prevent sleep disturbances.
Drug Interactions
Supplement/Herb/Nutrient-drug interactions can be dangerous and, in rare cases, even life-threatening. Always consult your doctor before supplementing and let them know about all drugs and supplements you are using or considering.
Due to its potential blood pressure-lowering effect, chlorogenic acid may cause blood pressure to drop too low in people already taking medication with this effect.
Chlorogenic acid may enhance the effects of metformin, a medication used to treat high blood sugar levels. However, this effect was only observed at much higher concentrations than those achieved by human blood after chlorogenic acid consumption.
Consult your doctor if you are taking any drugs (especially blood pressure-lowering and antidiabetic drugs) before supplementing with chlorogenic acid. *
