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Increased Risk of Lung Cancer with Supplements
Many studies have shown that high intake of carotenoids (beta-carotene) in supplement form significantly increases the risk of developing lung cancer in current and former smokers. One study, in particular, gave current smokers 20 milligrams per day of beta-carotene supplements for five to eight years.
The results showed a higher incidence in lung cancer in those receiving the supplement. However, the incidence of other major cancers wasn't affected. A similar study conducted with asbestos workers showed that they, too, may have a higher risk of developing lung cancer with high intake of carotenoid supplements.
However, remember that consuming ample fruits and vegetablesas part of an overall healthy diet has many benefits. In fact, dietary intake of carotenoids—as opposed to in supplement form—is associated with lower lung cancer risk.
Carotenemia
This is a condition in which the skin becomes yellowish because of a high amount of beta-carotene in the body.
Carotenemia is reversible, and while it is usually caused by intake through food, excessive intake via supplements can cause it, too.
Canthaxanthin Retinopathy
This condition is characterized by yellow-golden flecks in the eye, and sometimes vision field defects and problems with vision clarity. It is caused by taking high doses of a carotenoid called canthaxanthin. Fortunately, it is reversible: your eyes and vision will go back to normal once you stop consuming canthaxanthin.
Lycopenodermia
Taking high amounts of lycopene can cause your skin to temporarily become a deep orange color.
Allergic Reaction
As with many other substances, it is possible to have an allergic reaction to carotenoid supplements. You should see your physician immediately if you suspect you are having an allergic reaction. Itching, swelling, and rashes are typical signs of this.
Interactions with Medications
If you’re currently taking any medication, it’s best to consult with your physician before starting carotenoid supplements. Beta-carotene supplements, in particular, may have negative interactions with cholesterol-lowering drugs. *