Keep in mind that the safety profile of benfotiamine is relatively unknown, given the lack of well-designed clinical studies. The list of side effects below is not a definite one and you should consult your doctor about other potential side effects based on your health condition and possible drug or supplement interactions.
There have not been any adverse effects from benfotiamine alone reported in the scientific literature. However, there is anecdotal evidence of nausea, dizziness, and low blood pressure in some cases.
Drug Interactions
Supplement/Herb/Nutrient-drug interactions can be dangerous and, in rare cases, even life-threatening. Always consult your doctor before supplementing and let them know about all drugs and supplements you are using or considering.
Research on interactions involving benfotiamine and thiamine is lacking. Benfotiamine may be useful when taking medication or supplements that lower blood levels of vitamin B1, such as diuretics and certain heart medications.
Benfotiamine contains sulfur and is therefore not recommended for people with sulfur sensitivity. *
